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Seq and CLIP through the miRNA world

Nitish Mittal and Mihaela Zavolan*

Author Affiliations

Biozentrum, University of Basel, Klingelbergstrasse 50-70, Basel, Switzerland

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Genome Biology 2014, 15:202  doi:10.1186/gb4151

Published: 25 January 2014


High-throughput sequencing of RNAs crosslinked to Argonaute proteins reveals not only a multitude of atypical miRNA binding sites but also of miRNA targets with atypical functions, and can be used to infer quantitative models of miRNA-target interaction strength.