Methods for comprehensive experimental identification of RNA-protein interactions
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA
Genome Biology 2014, 15:203 doi:10.1186/gb4152Published: 27 January 2014
The importance of RNA-protein interactions in controlling mRNA regulation and non-coding RNA function is increasingly appreciated. A variety of methods exist to comprehensively define RNA-protein interactions. We describe these methods and the considerations required for designing and interpreting these experiments.