Open Access Highly Accessed Method

MOABS: model based analysis of bisulfite sequencing data

Deqiang Sun12, Yuanxin Xi12, Benjamin Rodriguez12, Hyun Jung Park12, Pan Tong12, Mira Meong3, Margaret A Goodell3 and Wei Li12*

Author Affiliations

1 Division of Biostatistics, Dan L. Duncan Cancer Center, Houston, TX 77030, USA

2 Department of Molecular and Cellular Biology, Houston, TX 77030, USA

3 Department of Pediatrics and Molecular & Human Genetics, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77030, USA

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Genome Biology 2014, 15:R38  doi:10.1186/gb-2014-15-2-r38

Published: 24 February 2014

Additional files

Additional file 1:

The source code for the software MOABS. This version is for archive purpose only. Please download the latest version from website.

Format: ZIP Size: 708KB Download file

Open Data

Additional file 2: Table S1:

Benchmark for performance of MOABS and BSmooth for reads alignment, methylation call, and differential methylation.

Format: XLSX Size: 51KB Download file

Open Data

Additional file 3:

The Additional Figures S1 to S5.

Format: PDF Size: 6.7MB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 4:

The testing data used for the Credible Difference method validation.

Format: DOCX Size: 47KB Download file

Open Data

Additional file 5: Table S2:

List of known imprinting DMRs with experimental validation references.

Format: XLS Size: 38KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 6: Table S3:

List of genes with decreased 5hmc and genes with increased 5hmc.

Format: XLSX Size: 45KB Download file

Open Data

Additional file 7:

This file is the section of additional method.

Format: DOCX Size: 1.5MB Download file

Open Data