Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Research highlight

Target competition: transcription factors enter the limelight

Florian A Karreth12, Yvonne Tay1 and Pier Paolo Pandolfi1*

Author Affiliations

1 Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

2 Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10021, USA

For all author emails, please log on.

Genome Biology 2014, 15:114  doi:10.1186/gb4174

Published: 28 April 2014

Abstract

Transcription factor binding sites compete for a limited pool of bioavailable transcription factor molecules to fine tune gene expression.