Target competition: transcription factors enter the limelight
1 Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
2 Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10021, USA
Genome Biology 2014, 15:114 doi:10.1186/gb4174Published: 28 April 2014
Transcription factor binding sites compete for a limited pool of bioavailable transcription factor molecules to fine tune gene expression.