Table 2

GO analysis with hypomethylated tDMRs
Tissue GO term Genes (n) P value
Adipose tissue (abdominal, subcutaneous) Lipid homeostasis 5 0.0096
White fat cell differentiation 3 0.0172
Fat cell differentiation 4 0.0532
Artery (coronary, splenic) Blood vessel morphogenesis 12 3.24E-04
Angiogenesis 10 4.25E-04
Blood vessel development 13 4.60E-04
Aorta (thoracic, abdominal) Cardiac muscle tissue development 11 5.91E-04
Muscle organ development 24 8.21E-04
Striated muscle tissue development 16 9.72E-04
Bone, joint cartilage Chondrocyte differentiation 3 0.0067
Cartilage development 4 0.0253
Skeletal system development 7 0.0553
Bone marrow (red, yellow) Cell activation 41 5.07E-07
Leukocyte activation 33 7.98E-06
Immune response 62 1.97E-05
Lymph node -
Tonsils Immune response 59 7.00E-06
Regulation of T cell activation 17 4.38E-05
Defense response 50 7.22E-05
Gastric mucosa Regulation of pH 2 0.0530
Monovalent inorganic cation homeostasis 2 0.0677
Bladder Muscle contraction 14 0.0034
Excretion 7 0.0266
Secretion 17 0.0379
Gall bladder Negative regulation of granulocyte differentiation 2 0.0417
Negative regulation of immune system process 3 0.0496
Regulation of granulocyte differentiation 2 0.0519
Medulla oblongata Homophilic cell adhesion 15 8.78E-06
Cell-cell adhesion 18 5.00E-04
Cell adhesion 25 0.0151
Ischiatic nerve Filopodium assembly 5 0.0023
Regulation of action potential in neuron 10 0.0036
Negative regulation of neurogenesis 7 0.0074

Lokk et al.

Lokk et al. Genome Biology 2014 15:r54   doi:10.1186/gb-2014-15-4-r54

Open Data