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Flipping the doublesex switch with a piRNA

Cale Whitworth* and Brian Oliver

Author Affiliations

Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 50 South Drive, Bethesda, MD 20892, USA

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Genome Biology 2014, 15:118  doi:10.1186/gb4181

Published: 24 June 2014

Abstract

Recent work in the silkworm Bombyx mori has uncovered a novel Piwi-interacting RNA regulator of the sex determination switch doublesex.