SUMO-specific proteases/isopeptidases: SENPs and beyond
Institute of Biochemistry II, Goethe University, Faculty of Medicine, Theodor-Stern-Kai 7, Frankfurt, 60590, Germany
Genome Biology 2014, 15:422 doi:10.1186/s13059-014-0422-2Published: 31 July 2014
We summarize the evolutionary relationship, structure and subcellular distribution of SUMO proteases (or SUMO isopeptidases). We also discuss their functions and allude to their involvement in human disease.