(9 February 2010)

The use of low coverage genomes in comparative evolutionary analyses to determine gene gain and loss events skews genome estimates.

(5 February 2010)

An automated method for constructing libraries for 454 sequencing significantly reduces the cost and time required.

(4 February 2010)

GOseq is a method for Gene Ontology analysis of RNA-seq data that takes into account the length bias inherent in RNA-seq.

(3 February 2010)

An algorithm for determining networks from gene expression data enables the identification of genes potentially linked to aging in worms.

(3 February 2010)

Genomic data together with sequencing of tissue specific small RNA libraries reveals insights into the genome content, small RNA repertoire and evolutionary origins of the grass Miscanthus x giganteus.

(3 February 2010)

Transcriptional profiling of specific regions of inbred rat brains reveals genes associated with alcohol preference in a known QTL locus on chromosome 4

(29 January 2010)

The genome sequence of the giant panda using next- generation sequencing marks a watershed in genome sequencing - in more ways than one.

(29 January 2010)

Huge advances in the field of genomics along with the continued rise of open access has made the past ten years an exciting time to be a biologist.

(28 January 2010)

An analysis of X-linked genetic variation in human populations provides insights into population structure and demographic patterns.

(28 January 2010)

Short-read sequencing technology can bring gigabase genome assemblies in under a million dollars.

(28 January 2010)

A genome-wide study of X chromosome genetic diversity in human populations shows the impact of social organization and local adaptation.

(28 January 2010)

Expressed Alu repeats are a reliable, accurate and universal reference for use in RT-qPCR normalization of human genes

(26 January 2010)

An inhibitor of microRNA-122 reduces viral load in chimpanzees that are chronically infected with hepatitis C virus, suggesting that such an approach might have therapeutic potential in humans.

(22 January 2010)

A new approach for genome-wide transcription factor binding site prediction is presented that integrates sequence and chromatin modification data.

(22 January 2010)

Twelve cDNA libraries from two species of catfish have been sequenced, resulting in the generation of nearly 500,000 ESTs.

(20 January 2010)

PhenomiR is a comprehensive database of 542 studies reporting deregulation of miRNAs allowing large-scale statistical analysis of miRNA expression changes.

(13 January 2010)

Nuclear myosin 1-dependent repositioning of chromosome territories occurs within 15 minutes of serum starvation in human cells.

(12 January 2010)

A new approach to detect deletions in divergentgenomes combines short read sequencing and tilling array data. Its utility is demonstrated on Arabidopsis strains.

(12 January 2010)

NetPath, a novel community resource of curated human signaling pathways is presented and its utility demonstrated using immune signaling data.

(8 January 2010)

A phenotypic ontology that can be used for the analysis of phenotype-genotype data across multiple species, paving the way for truly cross species translational research.