(17 March 2010)

Transcriptional profiling of Dictyostelium development reveals significant conservation of transcriptional profiles between evolutionarily divergent species.

(17 March 2010)

SplitSeek can be used to detect novel splicing events in SOLiD RNA-seq data without the need for a pre-defined library.

(16 March 2010)

New roles for the cytidine deaminase AID and elongator-complex proteins in DNA demethylation.

(16 March 2010)

The heat-shock protein Hsp90 has been shown to be involved in the repression of de novo transposon-mediated mutagenesis.

(15 March 2010)

Genome-wide mapping of the human TFIIB and NC2 transcription factor binding sites reveals insights into the formation of the pre-initiation complex.

(15 March 2010)

Pathicular a Cytoscape plugin for analysing cellular responses to transcription factor perturbations is presented

(15 March 2010)

The discovery of several new structured non-coding RNAs in bacterial and archaeal genomes and metagenomes raises burning questions about their biological and biochemical functions.

(15 March 2010)

Novel motifs identified in a comparative genomic analysis of bacterial, archaeal and metagenomic data reveals over 100 candidate structured RNAs.

(12 March 2010)

The of the relationship between co-fitness and co-inhibition of genes in chemicogenomic yeast screens provides insights into drug target prediction

(11 March 2010)

Genes with short 5'UTR introns have higher expression than genes with no or long 5'UTR introns. Complex evolutionary forces act on these introns.

(10 March 2010)

A method for determining false segmental duplications in vertebrate genomes, thus correcting mis-assemblies and providing more accurate estimates of duplications.

(9 March 2010)

XGAP, a software platform for the integration and analysis of genotype and phenotype data.

(8 March 2010)

Novel human pseudogenes are identified that had previous functionality and their age is estimated. The rate of loss-of-function occurred uniformly.

(2 March 2010)

A novel and empirical method for normalization of RNA-seq data is presented

(1 March 2010)

A high resolution strand-specific transcriptional atlas of the budding yeast mitotic cell cycle, including both mRNA and non-coding RNA profiles.

(26 February 2010)

Recent studies of the nematode dauer state provide new insights into epigenetic processes that underlie cellular memory.

(26 February 2010)

Objections to dividing biomedical research into 'translational' and 'basic' are not just a matter of semantics.

(26 February 2010)

Recent work shows that the histone methyltransferase PRDM9 determines the nonrandom genomic distribution of meiotic recombination hotspots.

(26 February 2010)

A gene set enrichment analysis method for including network topology in the identification of genes involved in phenotypic alterations is described. Classifications: Genome studies, Methods

(25 February 2010)

ChIA-PET Tool can be used to process long-range chromatin interaction data. Results are visualized on a user-friendly genome browser.