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2X genomes - depth does matter Michel C Milinkovitch, Raphael Helaers, Eric Depiereux, Athanasia C Tzika, Toni Gabaldon Genome Biology 2010, 11: R16
 (9 February 2010)
The use of low coverage genomes in comparative evolutionary analyses to determine gene gain and loss events skews genome estimates.
[Abstract] [Provisional PDF]
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A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454 Niall J Lennon, Robert E Lintner, Scott Anderson, Pablo Alvarez, Andrew Barry, William Brockman, Riza Daza, Rachel Erlich, Georgia Giannoukos, Lisa Green, Andrew Hollinger, Cindi A Hoover, David B Jaffe, Frank Juhn, Danielle McCarthy, Danielle Perrin, Karen Ponchner, Taryn L Powers, Kamran Rizzolo, Dana Robbins, Elizabeth Ryan, Carsten Russ, Todd Sparrow, John Stalker, Scott Steelman, Michael Weiand, Andrew Zimmer, Matthew R Henn, Chad Nusbaum, Robert Nicol Genome Biology 2010, 11: R15
 (5 February 2010)
An automated method for constructing libraries for 454 sequencing significantly reduces the cost and time required.
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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Genomic and small RNA sequencing of Miscanthus x giganteus shows the utility of sorghum as a reference genome sequence for Andropogoneae grasses Kankshita Swaminathan, Magdy Alabady, Kranthi Varala, Emanuele De Paoli, Isaac Ho, Dan S Rokhsar, Aru K Arumuganathan, Ray Ming, Pamela J Green, Blake C Meyers, Stephen P Moose, Matthew E Hudson Genome Biology 2010, 11: R12
 (3 February 2010)
Genomic data together with sequencing of tissue specific small RNA libraries reveals insights into the genome content, small RNA repertoire and evolutionary origins of the grass Miscanthus x giganteus.
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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Rising in the East Gregory A Petsko Genome Biology 2010, 11(1):102  (29 January 2010)
The genome sequence of the giant panda using next- generation sequencing marks a watershed in genome sequencing - in more ways than one.
[Abstract] [Full text] [PDF]
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Assembly of 500,000 inter-specific catfish expressed sequence tags and large scale gene-associated marker development for whole genome association studies Shaolin Wang, Eric Peatman, Jason Abernathy, Geoff Waldbieser, Erika Lindquist, Paul Richardson, Susan Lucas, Mei Wang, Ping Li, Jyothi Thimmapuram, Lei Liu, Deepika Vullaganti, Huseyin Kucuktas, Christopher Murdock, Brian C Small, Melanie Wilson, Hong Liu, Yanliang Jiang, Yoona Lee, Fei Chen, et al. Genome Biology 2010, 11: R8
 (22 January 2010)
Twelve cDNA libraries from two species of catfish have been sequenced, resulting in the generation of nearly 500,000 ESTs.
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes Andreas Ruepp, Andreas Kowarsch, Daniel Schmidl, Felix Buggenthin, Barbara Brauner, Irmtraud Dunger, Gisela Fobo, Goar Frishman, Corinna Montrone, Fabian J Theis Genome Biology 2010, 11: R6
  (20 January 2010)
PhenomiR is a comprehensive database of 542 studies reporting deregulation of miRNAs allowing large-scale statistical analysis of miRNA expression changes.
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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NetPath: a public resource of curated signal transduction pathways Kumaran Kandasamy, S Sujatha Mohan, Rajesh Raju, Shivakumar Keerthikumar, Ghantasala S Sameer Kumar, Abhilash K Venugopal, Deepthi Telikicherla, J Daniel Navarro, Suresh Mathivanan, Christian Pecquet, Sashi Kanth Gollapudi, Sudhir Gopal Tattikota, Shyam Mohan, Hariprasad Padhukasahasram, Yashwanth Subbannayya, Renu Goel, Harrys KC Jacob, Jun Zhong, Raja Sekhar, Vishalakshi Nanjappa, et al. Genome Biology 2010, 11: R3
  (12 January 2010)
NetPath, a novel community resource of curated human signaling pathways is presented and its utility demonstrated using immune signaling data.
[Abstract] [Provisional PDF] [PubMed] [Related articles]
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