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Research
 A critical assessment of Mus musculus gene function prediction using integrated genomic evidence Lourdes Peña-Castillo, Murat Tasan, Chad L Myers, Hyunju Lee, Trupti Joshi, Chao Zhang, Yuanfang Guan, Michele Leone, Andrea Pagnani, Wan Kyu Kim, Chase Krumpelman, Weidong Tian, Guillaume Obozinski, Yanjun Qi, Sara Mostafavi, Guan Ning Lin, Gabriel F Berriz, Francis D Gibbons, Gert Lanckriet, Jian Qiu, Charles Grant, Zafer Barutcuoglu, David P Hill, David Warde-Farley, Chris Grouios, Debajyoti Ray, Judith A Blake, Minghua Deng, Michael I Jordan, William S Noble, Quaid Morris, Judith Klein-Seetharaman, Ziv Bar-Joseph, Ting Chen, Fengzhu Sun, Olga G Troyanskaya, Edward M Marcotte, Dong Xu, Timothy R Hughes, Frederick P Roth Genome Biology 2008, 9(Suppl 1):S2 (27 June 2008) [Full text] [PDF]
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What makes pathogens pathogenic Garth D Ehrlich, N Luisa Hiller, Fen Ze Hu Genome Biology 2008, 9(6):225  (24 June 2008)
A review of the evolution of microbial pathogenicity in the context of the 'symbiome' of microbes and their multicellular hosts.
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Circular reasoning rather than cyclic expression Lars Juhl Jensen, Ulrik de Lichtenberg, Thomas Skøt Jensen, Søren Brunak, Peer Bork Genome Biology 2008, 9(6):403
 (23 June 2008)
A response to Combined analysis reveals a core set of cycling genes by Y Lu, S Mahony, PV Benos, R Rosenfeld, I Simon, LL Breeden and Z Bar-Joseph. Genome Biol 2007, 8:R146.
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It is alive Gregory A Petsko Genome Biology 2008, 9(6):106  (23 June 2008)
We need to familiarize ourselves with the facts of evolution, so that we can mount a spirited defense against creationism and the forces of ignorance.
[Abstract] [Full text] [PDF] [1 comment]
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Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype Edward K Lobenhofer, J Todd Auman, Pamela E Blackshear, Gary A Boorman, Pierre R Bushel, Michael L Cunningham, Jennifer M Fostel, Kevin Gerrish, Alexandra N Heinloth, Richard D Irwin, David E Malarkey, B Alex Merrick, Stella O Sieber, Charles J Tucker, Sandra M Ward, Ralph E Wilson, Patrick Hurban, Raymond W Tennant, Richard S Paules Genome Biology 2008, 9(6):R100
  (20 June 2008)
Histopathology, clinical chemistry, hematology and gene expression data were collected from the rat liver and blood after treatment with eight known hepatotoxins.
[Abstract] [Full text] [PDF] [PubMed] [Related articles]
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Sequencing the regulatory genome Stein Aerts, Stefanie Butland Genome Biology 2008, 9(6):313  (19 June 2008)
A report on the Cold Spring Harbor Laboratory meeting 'Systems Biology: Global Regulation of Gene Expression', Cold Spring Harbor, USA, 27-30 March 2008.
[Abstract] [Full text] [PDF]
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