Correction: Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases
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* Corresponding author: Ichizo Kobayashi ikobaya@ims.u-tokyo.ac.jp
1 Laboratory of Social Genome Sciences, Department of Medical Genome Sciences, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan
2 Graduate Program in Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan
3 International Institute of Molecular and Cell Biology, Trodena 4, 02-109 Warsaw, Poland
4 Faculty of Biology, Adam Mickiewicz University, Umultowska 89, 61-614 Poznan, Poland
5 Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan
Genome Biology 2011, 12:412 doi:10.1186/gb-2011-12-11-412
The electronic version of this article is the complete one and can be found online at: http://genomebiology.com/2012/12/11/412
| Received: | 16 November 2011 |
| Accepted: | 23 November 2011 |
| Published: | 15 January 2012 |
© 2012 BioMed Central Ltd.
Correction
We have noticed an error in the sixth paragraph of the Discussion of our article [1]. The corrected paragraph should read:
Another type IV nuclease, GmrSD, found in an E. coli strain targets glucosylated hydroxymethyl-C and may have evolved to cut T4 genome [78]. The resistance of hydroxymethyl-C-containing phage to restriction enzymes but its sensitivity to McrBC [79], the resistance of glucosylated hydroxymethyl-C to McrBC but sensitivity to GmrSD [78], and inhibition of GmrSD by T4-coded internal protein [78] suggest an evolutionary arms race (evolutionary struggle between competing sets of co-evolving genes that develop adaptations and counter-adaptations against each other) between the bacteria and the phage.
References
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Fukuda E, Kaminska KH, Bujnicki JM, Kobayashi I: Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases.
Genome Biology 2008, 9:R163. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text