Genome Biology | Volume 6 Issue 1

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	Volume 6 Issue 1
	Comment
	Editorial Editorial Genome Biology 2004, 6:101 (23 December 2004) Full text \| PDF \| PubMed
	Comment Identity crisis Gregory A Petsko Genome Biology 2004, 6:102 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary What we scientists need is a new name for ourselves, something that would give us the proper air of glamour, intrigue, and fascination.
	Opinion Gene Ontology: looking backwards and forwards Suzanna E Lewis Genome Biology 2004, 6:103 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Gene Ontology consortium began six years ago with a group of scientists who decided to connect our data by sharing the same language for describing it. Its most significant achievement lies in uniting many independent biological database efforts into a cooperative force.
	Review
	Protein family review The MAP2/Tau family of microtubule-associated proteins Leif Dehmelt, Shelley Halpain Genome Biology 2004, 6:204 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Microtubule-associated proteins (MAPs) of the MAP2/Tau family include the vertebrate proteins MAP2, MAP4, and Tau and homologs in other animals. They are best known for their microtubule-stabilizing activity roles regulating microtubule networks but, accumulating evidence suggests a much broader range of functions. regulation of microtubule-mediated transport. Tau is also implicated in Alzheimer’s disease and other dementias.
	Minireview Profiling gene expression in growth-arrested mouse embryos in diapause Eiichi Hondo, Colin L Stewart Genome Biology 2004, 6:202 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A recent report has identified changes in embryonic gene expression that are associated with, and may halt, embryonic cell proliferation during diapause.
	Minireview The latest buzz in comparative genomics Rob J Kulathinal, Daniel L Hartl Genome Biology 2005, 6:201 (4 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The publication of the Drosophila pseudoobscura sequence provides a snapshot of how genomes have changed over tens of millions of years.
	Report
	Paper report Articles selected by Faculty of 1000: the Methanococcus maripaludis genome; recombination in animal mitochondria; modulating cell cycle progression; gene silencing by microRNA directed methylation; yeast DNA breakage and repair Genome Biology 2004, 6:304 (8 December 2004) Abstract \| Full text \| Editor’s summary A selection of evaluations from Faculty of 1000 covering the Methanococcus maripaludis genome; recombination in animal mitochondria; modulating cell cycle progression; gene silencing by microRNA directed methylation; yeast DNA breakage and repair.
	Paper report Articles selected by Faculty of 1000: a TATA-box binding protein survey; Arabidopsis enzyme-activity profiling; cis-regulatory systems in Ascomycetes; Candida comparative genomics; a functional genomics pipeline Genome Biology 2004, 6:305 (21 December 2004) Abstract \| Full text \| Editor’s summary A selection of evaluations from Faculty of 1000 covering a TATA-box binding protein survey; Arabidopsis enzyme-activity profiling; cis-regulatory systems in Ascomycetes; Candida comparative genomics; a functional genomics pipeline.
	Meeting report Genome informatics: taming the avalanche of genomic data Erik LL Sonnhammer Genome Biology 2004, 6:301 (17 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A report on the fourth Cold Spring Harbor Laboratory/Wellcome Trust Conference on Genome Informatics, Hinxton, UK, 22-26 September 2004.
	Meeting report 'Horizontal' plant biology on the rise Yves Van de Peer Genome Biology 2004, 6:302 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the Plant Genomics European Meeting (Plant-GEMS2004), Lyon, France, 22-25 September 2004.
	Meeting report New animal models for evolution and development Kristin Tessmar-Raible, Detlev Arendt Genome Biology 2004, 6:303 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the annual UK Evolutionary Developmental Biology meeting, Oxford, UK, 13 September 2004.
	Tutorial Patenting inventions arising from biological research Matthew T Latimer Genome Biology 2004, 6:203 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This article describes the steps involved and the considerations needed for successful granting of a patent for biological ideas and technologies.
	Deposited research article Tracking the genetic imprints of lost Jewish tribes among the gene pool of Kuki-Chin-Mizo population of India Bhaswar Maity, T Sitalaximi, R Trivedi, VK Kashyap Genome Biology 2004, 6:P1 (2 December 2004) Abstract \| Full text \| PDF \| Editor’s summary DNA markers from the Kuki-Chin-Mizo population of Mizoram, India, who claim their descent from the ten lost tribes of Israel that were exiled by the Assyrians, show no evidence of Cohanim origin but some genetic relatedness to Near Eastern lineages.
	Deposited research article A tool for comparing different statistical methods on identifying differentially expressed genes Paul Fogel, Li Liu, Bruno Dumas, Nanxiang Ge Genome Biology 2004, 6:P2 (8 December 2004) Abstract \| Full text \| PDF \| Editor’s summary The authors have developed a procedure (a visualization method and associated variability conformation rate (VCR) criterion) that allows viewing and quantifying differences between method-dependent selections.
	Research news Maclyn McCarty dies Anne Harding Genome Biology 2004, 6:spotlight-20050111-01 (11 January 2005) Abstract \| Full text \| Editor’s summary Scientist who helped prove DNA is carrier of genetic information was 93
	Research news RNAi active in the nucleus? Cathy Holding Genome Biology 2004, 6:spotlight-20050112-01 (12 January 2005) Abstract \| Full text \| Editor’s summary US group says RNA interference takes place in the nucleus, but one expert is unconvinced
	Research news Fungus report stirs debate Charles Q Choi Genome Biology 2004, 6:spotlight-20050117-01 (17 January 2005) Abstract \| Full text \| Editor’s summary A paper suggesting ancient asexual fungi have more than one genome reignites controversy
	Research news Natural selection in humans Charles Q Choi Genome Biology 2004, 6:spotlight-20050118-01 (18 January 2005) Abstract \| Full text \| Editor’s summary A chromosomal inversion conveys a reproductive advantage in Iceland, researchers report
	Research news Pokemon's cancer role revealed Marta Paterlini Genome Biology 2004, 6:spotlight-20050120-01 (20 January 2005) Abstract \| Full text \| Editor’s summary Important new insights into neoplastic development provided by report in
	Research news Giardia's sex life revealed Charles Q Choi Genome Biology 2004, 6:spotlight-20050127-01 (27 January 2005) Abstract \| Full text \| Editor’s summary The protist has homologs of proteins with crucial roles in meiosis, researchers show
	Research news How RNA polymerase moves Charles Q Choi Genome Biology 2004, 6:spotlight-20050128-01 (28 January 2005) Abstract \| Full text \| Editor’s summary The molecule appears to shift along nucleic acid using a ratchet system, researchers report
	Research
	Research Global expression changes resulting from loss of telomeric DNA in fission yeast Jeffrey G Mandell, Jürg Bähler, Thomas A Volpe, Robert A Martienssen, Thomas R Cech Genome Biology 2004, 6:R1 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Gene expression profiling of the response of Schizosaccharomyces pombe cells to loss of the catalytic subunit of telomerase (trt1⁺) identified two waves of altered gene expression and a continued up-regulation of Core Environmental stress Response (CESR) genes.
	Research Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels Asba Tasneem, Lakshminarayan M Iyer, Eric Jakobsson, L Aravind Genome Biology 2004, 6:R4 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Acetylcholine receptor type ligand-gated ion channels are well known in animals. Homologs are identified in prokaryotes that may act as chemotactic receptors.
	Research Computational prediction of human metabolic pathways from the complete human genome Pedro Romero, Jonathan Wagg, Michelle L Green, Dale Kaiser, Markus Krummenacker, Peter D Karp Genome Biology 2004, 6:R2 (22 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A computation pathway analysis of the human genome is presented that assigns enzymes encoded by the genome to predicted metabolic pathways. This analysis provides a genome-based view of human nutrition.
	Research Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease Maho Niwa, Christopher K Patil, Joe DeRisi, Peter Walter Genome Biology 2004, 6:R3 (22 December 2004) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology \| Editor’s summary Three different genome-scale screens indicate that the HAC1 mRNA is the only substrate for the Ire1 nuclease in yeast.
	Research Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice Lisa Cooper, Claire Johnson, Frank Burslem, Paul Martin Genome Biology 2004, 6:R5 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary To define the events in wound healing that are independent of inflammation, gene expression during wound healing was profiled in wild-type mice and PU.1 null mice, which cannot raise the standard inflammatory response but which can repair skin wounds rapidly.
	Method Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry Frank Desiere, Eric W Deutsch, Alexey I Nesvizhskii, Parag Mallick, Nichole L King, Jimmy K Eng, Alan Aderem, Rose Boyle, Erich Brunner, Samuel Donohoe, Nelson Fausto, Ernst Hafen, Lee Hood, Michael G Katze, Kathleen A Kennedy, Floyd Kregenow, Hookeun Lee, Biaoyang Lin, Dan Martin, Jeffrey A Ranish, David J Rawlings, Lawrence E Samelson, Yuzuru Shiio, Julian D Watts, Bernd Wollscheid, Michael E Wright, Wei Yan, Lihong Yang, Eugene C Yi, Hui Zhang, Ruedi Aebersold et al. Genome Biology 2004, 6:R9 (10 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Peptides derived from protein tandem mass spectrometry data have been mapped to the human genome sequence forming an expandable resource for the proteomic data.
	Method The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information Cynthia L Smith, Carroll-Ann W Goldsmith, Janan T Eppig Genome Biology 2004, 6:R7 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Mammalian Phenotype (MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and disease.
	Method Microarray-based resequencing of multiple Bacillus anthracis isolates Michael E Zwick, Farrell Mcafee, David J Cutler, Timothy D Read, Jacques Ravel, Gregory R Bowman, Darrell R Galloway, Alfred Mateczun Genome Biology 2004, 6:R10 (17 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Custom-designed resequencing arrays were used to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication and by comparison to independently generated shotgun sequence
	Method Using ontologies to describe mouse phenotypes Georgios V Gkoutos, Eain CJ Green, Ann-Marie Mallon, John M Hancock, Duncan Davidson Genome Biology 2004, 6:R8 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary By combining ontologies from different sources the authors developed a novel approach to describing phenotypes of mutant mice in a standard, structured manner.
	Method Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis Randolph B Caldwell, Andrzej M Kierzek, Hiroshi Arakawa, Yuri Bezzubov, Jolanta Zaim, Petra Fiedler, Stefan Kutter, Artem Blagodatski, Diyana Kostovska, Marek Koter, Jiri Plachy, Piero Carninci, Yoshihide Hayashizaki, Jean-Marie Buerstedde Genome Biology 2004, 6:R6 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This article reports a cDNA collection representing more than 2000 new, full-length transcripts from a high-quality cDNA library.

	Volume 6 Issue 1
	Comment
	Editorial Editorial Genome Biology 2004, 6:101 (23 December 2004) Full text \| PDF \| PubMed
	Comment Identity crisis Gregory A Petsko Genome Biology 2004, 6:102 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary What we scientists need is a new name for ourselves, something that would give us the proper air of glamour, intrigue, and fascination.
	Opinion Gene Ontology: looking backwards and forwards Suzanna E Lewis Genome Biology 2004, 6:103 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Gene Ontology consortium began six years ago with a group of scientists who decided to connect our data by sharing the same language for describing it. Its most significant achievement lies in uniting many independent biological database efforts into a cooperative force.
	Review
	Protein family review The MAP2/Tau family of microtubule-associated proteins Leif Dehmelt, Shelley Halpain Genome Biology 2004, 6:204 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Microtubule-associated proteins (MAPs) of the MAP2/Tau family include the vertebrate proteins MAP2, MAP4, and Tau and homologs in other animals. They are best known for their microtubule-stabilizing activity roles regulating microtubule networks but, accumulating evidence suggests a much broader range of functions. regulation of microtubule-mediated transport. Tau is also implicated in Alzheimer’s disease and other dementias.
	Minireview Profiling gene expression in growth-arrested mouse embryos in diapause Eiichi Hondo, Colin L Stewart Genome Biology 2004, 6:202 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A recent report has identified changes in embryonic gene expression that are associated with, and may halt, embryonic cell proliferation during diapause.
	Minireview The latest buzz in comparative genomics Rob J Kulathinal, Daniel L Hartl Genome Biology 2005, 6:201 (4 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The publication of the Drosophila pseudoobscura sequence provides a snapshot of how genomes have changed over tens of millions of years.
	Report
	Paper report Articles selected by Faculty of 1000: the Methanococcus maripaludis genome; recombination in animal mitochondria; modulating cell cycle progression; gene silencing by microRNA directed methylation; yeast DNA breakage and repair Genome Biology 2004, 6:304 (8 December 2004) Abstract \| Full text \| Editor’s summary A selection of evaluations from Faculty of 1000 covering the Methanococcus maripaludis genome; recombination in animal mitochondria; modulating cell cycle progression; gene silencing by microRNA directed methylation; yeast DNA breakage and repair.
	Paper report Articles selected by Faculty of 1000: a TATA-box binding protein survey; Arabidopsis enzyme-activity profiling; cis-regulatory systems in Ascomycetes; Candida comparative genomics; a functional genomics pipeline Genome Biology 2004, 6:305 (21 December 2004) Abstract \| Full text \| Editor’s summary A selection of evaluations from Faculty of 1000 covering a TATA-box binding protein survey; Arabidopsis enzyme-activity profiling; cis-regulatory systems in Ascomycetes; Candida comparative genomics; a functional genomics pipeline.
	Meeting report Genome informatics: taming the avalanche of genomic data Erik LL Sonnhammer Genome Biology 2004, 6:301 (17 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A report on the fourth Cold Spring Harbor Laboratory/Wellcome Trust Conference on Genome Informatics, Hinxton, UK, 22-26 September 2004.
	Meeting report 'Horizontal' plant biology on the rise Yves Van de Peer Genome Biology 2004, 6:302 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the Plant Genomics European Meeting (Plant-GEMS2004), Lyon, France, 22-25 September 2004.
	Meeting report New animal models for evolution and development Kristin Tessmar-Raible, Detlev Arendt Genome Biology 2004, 6:303 (21 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the annual UK Evolutionary Developmental Biology meeting, Oxford, UK, 13 September 2004.
	Tutorial Patenting inventions arising from biological research Matthew T Latimer Genome Biology 2004, 6:203 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary This article describes the steps involved and the considerations needed for successful granting of a patent for biological ideas and technologies.
	Deposited research article Tracking the genetic imprints of lost Jewish tribes among the gene pool of Kuki-Chin-Mizo population of India Bhaswar Maity, T Sitalaximi, R Trivedi, VK Kashyap Genome Biology 2004, 6:P1 (2 December 2004) Abstract \| Full text \| PDF \| Editor’s summary DNA markers from the Kuki-Chin-Mizo population of Mizoram, India, who claim their descent from the ten lost tribes of Israel that were exiled by the Assyrians, show no evidence of Cohanim origin but some genetic relatedness to Near Eastern lineages.
	Deposited research article A tool for comparing different statistical methods on identifying differentially expressed genes Paul Fogel, Li Liu, Bruno Dumas, Nanxiang Ge Genome Biology 2004, 6:P2 (8 December 2004) Abstract \| Full text \| PDF \| Editor’s summary The authors have developed a procedure (a visualization method and associated variability conformation rate (VCR) criterion) that allows viewing and quantifying differences between method-dependent selections.
	Research news Maclyn McCarty dies Anne Harding Genome Biology 2004, 6:spotlight-20050111-01 (11 January 2005) Abstract \| Full text \| Editor’s summary Scientist who helped prove DNA is carrier of genetic information was 93
	Research news RNAi active in the nucleus? Cathy Holding Genome Biology 2004, 6:spotlight-20050112-01 (12 January 2005) Abstract \| Full text \| Editor’s summary US group says RNA interference takes place in the nucleus, but one expert is unconvinced
	Research news Fungus report stirs debate Charles Q Choi Genome Biology 2004, 6:spotlight-20050117-01 (17 January 2005) Abstract \| Full text \| Editor’s summary A paper suggesting ancient asexual fungi have more than one genome reignites controversy
	Research news Natural selection in humans Charles Q Choi Genome Biology 2004, 6:spotlight-20050118-01 (18 January 2005) Abstract \| Full text \| Editor’s summary A chromosomal inversion conveys a reproductive advantage in Iceland, researchers report
	Research news Pokemon's cancer role revealed Marta Paterlini Genome Biology 2004, 6:spotlight-20050120-01 (20 January 2005) Abstract \| Full text \| Editor’s summary Important new insights into neoplastic development provided by report in
	Research news Giardia's sex life revealed Charles Q Choi Genome Biology 2004, 6:spotlight-20050127-01 (27 January 2005) Abstract \| Full text \| Editor’s summary The protist has homologs of proteins with crucial roles in meiosis, researchers show
	Research news How RNA polymerase moves Charles Q Choi Genome Biology 2004, 6:spotlight-20050128-01 (28 January 2005) Abstract \| Full text \| Editor’s summary The molecule appears to shift along nucleic acid using a ratchet system, researchers report
	Research
	Research Global expression changes resulting from loss of telomeric DNA in fission yeast Jeffrey G Mandell, Jürg Bähler, Thomas A Volpe, Robert A Martienssen, Thomas R Cech Genome Biology 2004, 6:R1 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Gene expression profiling of the response of Schizosaccharomyces pombe cells to loss of the catalytic subunit of telomerase (trt1⁺) identified two waves of altered gene expression and a continued up-regulation of Core Environmental stress Response (CESR) genes.
	Research Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels Asba Tasneem, Lakshminarayan M Iyer, Eric Jakobsson, L Aravind Genome Biology 2004, 6:R4 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Acetylcholine receptor type ligand-gated ion channels are well known in animals. Homologs are identified in prokaryotes that may act as chemotactic receptors.
	Research Computational prediction of human metabolic pathways from the complete human genome Pedro Romero, Jonathan Wagg, Michelle L Green, Dale Kaiser, Markus Krummenacker, Peter D Karp Genome Biology 2004, 6:R2 (22 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A computation pathway analysis of the human genome is presented that assigns enzymes encoded by the genome to predicted metabolic pathways. This analysis provides a genome-based view of human nutrition.
	Research Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease Maho Niwa, Christopher K Patil, Joe DeRisi, Peter Walter Genome Biology 2004, 6:R3 (22 December 2004) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology \| Editor’s summary Three different genome-scale screens indicate that the HAC1 mRNA is the only substrate for the Ire1 nuclease in yeast.
	Research Wound healing and inflammation genes revealed by array analysis of 'macrophageless' PU.1 null mice Lisa Cooper, Claire Johnson, Frank Burslem, Paul Martin Genome Biology 2004, 6:R5 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary To define the events in wound healing that are independent of inflammation, gene expression during wound healing was profiled in wild-type mice and PU.1 null mice, which cannot raise the standard inflammatory response but which can repair skin wounds rapidly.
	Method Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry Frank Desiere, Eric W Deutsch, Alexey I Nesvizhskii, Parag Mallick, Nichole L King, Jimmy K Eng, Alan Aderem, Rose Boyle, Erich Brunner, Samuel Donohoe, Nelson Fausto, Ernst Hafen, Lee Hood, Michael G Katze, Kathleen A Kennedy, Floyd Kregenow, Hookeun Lee, Biaoyang Lin, Dan Martin, Jeffrey A Ranish, David J Rawlings, Lawrence E Samelson, Yuzuru Shiio, Julian D Watts, Bernd Wollscheid, Michael E Wright, Wei Yan, Lihong Yang, Eugene C Yi, Hui Zhang, Ruedi Aebersold et al. Genome Biology 2004, 6:R9 (10 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Peptides derived from protein tandem mass spectrometry data have been mapped to the human genome sequence forming an expandable resource for the proteomic data.
	Method The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information Cynthia L Smith, Carroll-Ann W Goldsmith, Janan T Eppig Genome Biology 2004, 6:R7 (15 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The Mammalian Phenotype (MP) Ontology enables robust annotation of mammalian phenotypes in the context of mutations, quantitative trait loci and strains that are used as models of human biology and disease.
	Method Microarray-based resequencing of multiple Bacillus anthracis isolates Michael E Zwick, Farrell Mcafee, David J Cutler, Timothy D Read, Jacques Ravel, Gregory R Bowman, Darrell R Galloway, Alfred Mateczun Genome Biology 2004, 6:R10 (17 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Custom-designed resequencing arrays were used to generate 3.1 Mb of genomic sequence from a panel of 56 Bacillus anthracis strains. Sequence quality was shown to be very high by replication and by comparison to independently generated shotgun sequence
	Method Using ontologies to describe mouse phenotypes Georgios V Gkoutos, Eain CJ Green, Ann-Marie Mallon, John M Hancock, Duncan Davidson Genome Biology 2004, 6:R8 (20 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary By combining ontologies from different sources the authors developed a novel approach to describing phenotypes of mutant mice in a standard, structured manner.
	Method Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis Randolph B Caldwell, Andrzej M Kierzek, Hiroshi Arakawa, Yuri Bezzubov, Jolanta Zaim, Petra Fiedler, Stefan Kutter, Artem Blagodatski, Diyana Kostovska, Marek Koter, Jiri Plachy, Piero Carninci, Yoshihide Hayashizaki, Jean-Marie Buerstedde Genome Biology 2004, 6:R6 (23 December 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary This article reports a cDNA collection representing more than 2000 new, full-length transcripts from a high-quality cDNA library.

Explore Genome Biology

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Volume 6 Issue 1

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Review

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