|
Top 25 performing SeqFEATURE models |
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| Model name |
AUC |
Z-cutoff-100 |
Sens-100 |
Z-cutoff-99 |
Sens-99 |
Z-cutoff-95 |
Sens-95 |
No. of examples |
|
|
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| ADH_ZINC.2.HIS.ND1 |
1.0000 |
3.4172 |
1.0000 |
2.4184 |
1.0000 |
1.7128 |
1.0000 |
6 |
| CARBOXYLESTERASE_B_1.11.SER.OG |
1.0000 |
5.2823 |
1.0000 |
2.5415 |
1.0000 |
1.7047 |
1.0000 |
6 |
| GLYCOSYL_HYDROL_F5.7.GLU.OE1 |
1.0000 |
3.8385 |
1.0000 |
2.7188 |
1.0000 |
1.8787 |
1.0000 |
6 |
| HIPIP.7.CYS.SG |
1.0000 |
4.8473 |
1.0000 |
2.7401 |
1.0000 |
1.7795 |
1.0000 |
5 |
| RNASE_T2_1.4.HIS.NE2 |
1.0000 |
4.0910 |
1.0000 |
2.6209 |
1.0000 |
1.6521 |
1.0000 |
5 |
| THIOL_PROTEASE_ASN.6.ASN.ND2 |
1.0000 |
3.8379 |
1.0000 |
2.5982 |
1.0000 |
1.8237 |
1.0000 |
5 |
| THIOL_PROTEASE_ASN.6.ASN.OD1 |
1.0000 |
4.1252 |
1.0000 |
2.6255 |
1.0000 |
1.7985 |
1.0000 |
5 |
| TYR_PHOSPHATASE_1.3.CYS.SG |
1.0000 |
5.4246 |
1.0000 |
2.7473 |
1.0000 |
1.7596 |
1.0000 |
8 |
| CYTOCHROME_P450.8.CYS.SG |
1.0000 |
4.1254 |
0.8333 |
2.4019 |
1.0000 |
1.7526 |
1.0000 |
12 |
| PEROXIDASE_2.8.HIS.ND1 |
0.9999 |
3.6628 |
0.8000 |
2.6225 |
1.0000 |
1.7515 |
1.0000 |
5 |
| BPTI_KUNITZ_1.8.CYS.SG |
0.9999 |
3.5059 |
0.8333 |
2.2843 |
1.0000 |
1.7820 |
1.0000 |
6 |
| 4FE4S_FERREDOXIN.5.CYS.SG |
0.9999 |
2.7500 |
0.4000 |
1.5623 |
1.0000 |
1.2660 |
1.0000 |
17 |
| ADH_SHORT.3.TYR.OH |
0.9999 |
5.0745 |
0.1176 |
2.2891 |
1.0000 |
1.6249 |
1.0000 |
20 |
| TRYPSIN_SER.6.SER.OG |
0.9998 |
5.4646 |
0.0000 |
2.1696 |
1.0000 |
1.6085 |
1.0000 |
17 |
| GLYCOSYL_HYDROL_F5.7.GLU.OE2 |
0.9998 |
3.9203 |
0.8333 |
2.6280 |
1.0000 |
1.8757 |
1.0000 |
6 |
| 4FE4S_FERREDOXIN.1.CYS.SG |
0.9998 |
3.1084 |
0.1000 |
2.0501 |
1.0000 |
1.5589 |
1.0000 |
20 |
| PEROXIDASE_2.8.HIS.NE2 |
0.9997 |
3.9233 |
0.6000 |
2.5753 |
1.0000 |
1.8144 |
1.0000 |
5 |
| BETA_LACTAMASE_B_1.6.HIS.ND1 |
0.9997 |
5.3466 |
0.8000 |
2.7205 |
1.0000 |
1.7821 |
1.0000 |
5 |
| ADH_ZINC.2.HIS.NE2 |
0.9996 |
3.8970 |
0.6667 |
2.4840 |
1.0000 |
1.7499 |
1.0000 |
6 |
| LIPASE_SER.7.SER.OG |
0.9995 |
4.7293 |
0.6250 |
2.5387 |
1.0000 |
1.7350 |
1.0000 |
8 |
| ASP_PROTEASE.4.ASP.OD2 |
0.9994 |
3.7837 |
0.4706 |
2.2973 |
1.0000 |
1.7238 |
1.0000 |
17 |
| IMP_1.4.ASP.OD2 |
0.9994 |
3.9608 |
0.6000 |
2.5508 |
1.0000 |
1.8129 |
1.0000 |
5 |
| BETA_LACTAMASE_B_1.4.HIS.ND1 |
0.9993 |
3.8683 |
0.8000 |
2.6032 |
1.0000 |
1.8239 |
1.0000 |
5 |
| BETA_LACTAMASE_B_1.8.ASP.OD1 |
0.9991 |
4.6363 |
0.6000 |
2.9202 |
1.0000 |
1.8558 |
1.0000 |
5 |
| 4FE4S_FERREDOXIN.3.CYS.SG |
0.9991 |
3.4191 |
0.0000 |
2.0044 |
0.9500 |
1.4919 |
1.0000 |
20 |
|
For each model, we report (from left to right) the AUC, the Z-score for which all negatives are correctly predicted, the sensitivity (Sens) at this Z-score, the Z-score for which 99% of negatives are correctly predicted, the associated sensitivity, and the Z-score and associated sensitivity for 95%. The final column reports the number of positive examples of the one-dimensional motif found in the ASTRAL40 compendium of the PDB. | ||||||||
Wu et al. Genome Biology 2008 9:R8 doi:10.1186/gb-2008-9-1-r8 |
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