rank gene gband SNV.Indel HLAMP AMP HOMD HETD covered_events node_degree p.value CGC.status percentage.event as.character(p.way) 1 PLCG2 16q23.2 0 0 1 12 520 45446 2455 0 0 0.535678391959799 B cell receptor signaling pathway(K)(0.9941778)-Calcium signaling pathway(K)(0.9987394)-EGF receptor signaling pathway(P)(0.9927392)-EGFR1(C)(0.9992476)-EPO signaling pathway(N)(0.9888032)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9937572)-ErbB signaling pathway(K)(0.9964746)-FGF signaling pathway(P)(0.9933178)-Fc epsilon RI signaling pathway(K)(0.9853508)-Fc gamma R-mediated phagocytosis(K)(0.9979204)-Formation of Platelet plug(R)(0.9989208)-Glypican pathway(N)(0.997813)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9962668)-Inositol phosphate metabolism(K)(0.9879412)-Leukocyte transendothelial migration(K)(0.9986518)-Metabolic pathways(K)(0.9978396)-Natural killer cell mediated cytotoxicity(K)(0.9962686)-Neurotrophin signaling pathway(K)(0.9968264)-Pathways in cancer(K)(0.9976192)-TRAIL signaling pathway(N)(0.9978864)-VEGF signaling pathway(K)(0.9885698)-Vibrio cholerae infection(K)(0.9945038) 2 ARRB2 17p13.2 0 0 1 5 407 27755 2176 0 0 0.415075376884422 Chemokine signaling pathway(K)(0.9973044)-Endocytosis(K)(0.9989852)-Glypican pathway(N)(0.991399)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9975316)-IFN-gamma pathway(N)(0.9966282)-IL1-mediated signaling events(N)(0.9898302)-IL12-mediated signaling events(N)(0.9958796)-IL2-mediated signaling events(N)(0.9892804)-IL23-mediated signaling events(N)(0.9759978)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.994729)-LPA receptor mediated events(N)(0.9844532)-MAPK signaling pathway(K)(0.9980374)-Olfactory transduction(K)(0.9990116)-Phototransduction(K)(0.9902474)-Plasma membrane estrogen receptor signaling(N)(0.9694834)-Proteogylcan syndecan-mediated signaling events(N)(0.996071)-Signaling by Aurora kinases(N)(0.9638732)-Signaling events mediated by the Hedgehog family(N)(0.996227)-Signaling events regulated by Ret tyrosine kinase(N)(0.9854112)-TCR signaling in naive CD4+ T cells(N)(0.9695054)-TGFBR(C)(0.9971468)-TNF receptor signaling pathway(N)(0.988841)-TRAIL signaling pathway(N)(0.9865256)-Thromboxane A2 receptor signaling(N)(0.9853746)-Wnt signaling pathway(P)(0.9990316)-Wnt(C)(0.9949798)-p75(NTR)-mediated signaling(N)(0.997903) 3 POLR2A 17p13.1 0 0 0 6 409 16504 1654 0 0 0.417085427135678 DNA Repair(R)(0.9979398)-Formation and Maturation of mRNA Transcript(R)(0.9968528)-HIV Life Cycle(R)(0.9943234)-Huntington's disease(K)(0.9994318)-Influenza Life Cycle(R)(0.997504)-Metabolic pathways(K)(0.9993666)-Purine metabolism(K)(0.9949088)-Pyrimidine metabolism(K)(0.9880374)-Regulatory RNA pathways(R)(0.9894544)-Transcription(R)(0.9970592)-mRNA Processing(R)(0.99157)-repression of pain sensation by the transcriptional regulator dream(B)(0.9914216)-telomeres telomerase cellular aging and immortality(B)(0.996261) 4 MAPK1 22q11.22 0 0 4 1 276 12792 2676 0 0 0.282412060301508 Adherens junction(K)(0.990368)-Aldosterone-regulated sodium reabsorption(K)(0.9952032)-Alzheimer disease-amyloid secretase pathway(P)(0.9924664)-Alzheimer's disease(K)(0.997926)-AndrogenReceptor(C)(0.9954544)-Angiogenesis(P)(0.8593094)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9890588)-Apoptosis signaling pathway(P)(0.9514604)-Axon guidance(K)(0.9992612)-B cell receptor signaling pathway(K)(0.9807652)-BMP receptor signaling(N)(0.9837792)-Cellular roles of Anthrax toxin(N)(0.9503844)-Chagas disease(K)(0.9774318)-Chemokine signaling pathway(K)(0.9986258)-Dorso-ventral axis formation(K)(0.9914778)-EGF receptor signaling pathway(P)(0.9429194)-EGFR1(C)(0.9964966)-Endothelins(N)(0.983486)-ErbB signaling pathway(K)(0.951607)-Fc gamma R-mediated phagocytosis(K)(0.9958764)-Fc-epsilon receptor I signaling in mast cells(N)(0.978953)-Focal adhesion(K)(0.994805)-Gap junction(K)(0.997138)-Glypican pathway(N)(0.9903816)-GnRH signaling pathway(K)(0.9885704)-IFN-gamma pathway(N)(0.905315)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9622198)-Insulin signaling pathway(K)(0.9991592)-Integrin signalling pathway(P)(0.9974522)-Integrins in angiogenesis(N)(0.9910072)-Interleukin signaling pathway(P)(0.9446114)-KitReceptor(C)(0.975265)-Leishmaniasis(K)(0.9670582)-Long-term depression(K)(0.9842626)-Long-term potentiation(K)(0.9015424)-MAPK signaling pathway(K)(0.9984752)-NOD-like receptor signaling pathway(K)(0.992984)-NOTCH(C)(0.9956056)-Natural killer cell mediated cytotoxicity(K)(0.9973038)-Neurotrophin signaling pathway(K)(0.9706914)-Oocyte meiosis(K)(0.995191)-Parkinson disease(P)(0.9918716)-Pathways in cancer(K)(0.998661)-Plasma membrane estrogen receptor signaling(N)(0.933641)-Prion diseases(K)(0.9726556)-Progesterone-mediated oocyte maturation(K)(0.9689568)-Prostate cancer(K)(0.9533748)-Proteogylcan syndecan-mediated signaling events(N)(0.9965754)-Regulation of Telomerase(N)(0.9980226)-Regulation of actin cytoskeleton(K)(0.9983526)-Retinoic acid receptors-mediated signaling(N)(0.9751046)-Shigellosis(K)(0.966426)-Signaling by EGFR(R)(0.9328576)-Signaling events mediated by PRL(N)(0.9832576)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9567814)-Signaling events regulated by Ret tyrosine kinase(N)(0.9781376)-Signalling by NGF(R)(0.99645)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9853904)-T cell receptor signaling pathway(K)(0.8474184)-TCR signaling in naive CD4+ T cells(N)(0.972817)-TGF-beta signaling pathway(K)(0.9948986)-TGF-beta signaling pathway(P)(0.9942308)-TNF receptor signaling pathway(N)(0.9757912)-Toll-like receptor signaling pathway(K)(0.995839)-Type II diabetes mellitus(K)(0.9795708)-Vascular smooth muscle contraction(K)(0.9972752)-agrin in postsynaptic differentiation(B)(0.9888436)-how progesterone initiates the oocyte maturation(B)(0.9456906)-il-10 anti-inflammatory signaling pathway(B)(0.9567476)-il-2 receptor beta chain in t cell activation(B)(0.9260244)-lectin induced complement pathway(B)(0.9674)-mTOR signaling pathway(K)(0.9865906)-mcalpain and friends in cell motility(B)(0.9158328)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9910608)-p38 mapk signaling pathway(B)(0.9679714)-p75(NTR)-mediated signaling(N)(0.9974754)-role of erbb2 in signal transduction and oncology(B)(0.952085)-t cell receptor signaling pathway(B)(0.8972232)-tpo signaling pathway(B)(0.9214364) 5 PPP3CC 8p21.3 0 0 1 35 373 8487 1612 0 0 0.41105527638191 Alzheimer's disease(K)(0.9975386)-Amyotrophic lateral sclerosis (ALS)(K)(0.9954096)-Apoptosis(K)(0.9912952)-Apoptosis(R)(0.9959744)-Axon guidance(K)(0.999173)-B cell receptor signaling pathway(K)(0.9921726)-Calcium signaling pathway(K)(0.997052)-Glypican pathway(N)(0.9969508)-Long-term potentiation(K)(0.950342)-MAPK signaling pathway(K)(0.9995258)-Natural killer cell mediated cytotoxicity(K)(0.9950922)-Oocyte meiosis(K)(0.9949282)-Opioid Signalling(R)(0.9967446)-T cell receptor signaling pathway(K)(0.9902944)-TRAIL signaling pathway(N)(0.9949078)-VEGF signaling pathway(K)(0.9936232)-Wnt signaling pathway(K)(0.997862)-Wnt signaling pathway(P)(0.9990276) 6 HSPA8 11q24.1 0 0 1 15 375 6213 1264 0 0 0.392964824120603 Antigen processing and presentation(K)(0.9963)-Endocytosis(K)(0.9971962)-Glypican pathway(N)(0.998081)-IFN-gamma pathway(N)(0.9980426)-MAPK signaling pathway(K)(0.9994098)-Membrane Trafficking(R)(0.9944866)-Parkinson disease(P)(0.9950058)-Protein processing in endoplasmic reticulum(K)(0.9976768)-Spliceosome(K)(0.9973212)-TGFBR(C)(0.9969814) 7 EP300 22q13.2 0 0 0 4 323 5734 2220 0 1 0.328643216080402 Adherens junction(K)(0.9969694)-Androgen-mediated signaling(N)(0.9304016)-AndrogenReceptor(C)(0.9938088)-BMP receptor signaling(N)(0.9891484)-Cell cycle(K)(0.9985796)-Endothelins(N)(0.9879058)-FOXA transcription factor networks(N)(0.9855734)-FOXM1 transcription factor network(N)(0.9919486)-FoxO family signaling(N)(0.9747876)-Glypican pathway(N)(0.996392)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9976134)-Huntington disease(P)(0.9977248)-Huntington's disease(K)(0.998797)-Hypoxia response via HIF activation(P)(0.9350116)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9866874)-IFN-gamma pathway(N)(0.9972602)-IL1-mediated signaling events(N)(0.9917778)-Jak-STAT signaling pathway(K)(0.9983948)-KitReceptor(C)(0.9769084)-Long-term potentiation(K)(0.9942374)-Melanogenesis(K)(0.9572064)-NOTCH(C)(0.9945796)-Notch signaling pathway(K)(0.9925866)-Pathways in cancer(K)(0.9992486)-Plasma membrane estrogen receptor signaling(N)(0.9913664)-Prostate cancer(K)(0.9755406)-Regulation of retinoblastoma protein(N)(0.990932)-Renal cell carcinoma(K)(0.9770832)-Retinoic acid receptors-mediated signaling(N)(0.962063)-Signaling events mediated by HDAC Class I(N)(0.9963868)-TGF-beta signaling pathway(K)(0.994832)-TGF-beta signaling pathway(P)(0.9916406)-TGFBR(C)(0.9953582)-TNF receptor signaling pathway(N)(0.9928482)-TRAIL signaling pathway(N)(0.9901366)-Wnt signaling pathway(K)(0.9949936)-Wnt signaling pathway(P)(0.9969232)-Wnt(C)(0.9930666)-cell cycle: g2/m checkpoint(B)(0.9484236)-granzyme a mediated apoptosis pathway(B)(0.9691056)-hypoxia and p53 in the cardiovascular system(B)(0.9707392)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9927224)-nfat and hypertrophy of the heart (B)(0.9945626)-p53 pathway(P)(0.883945)-regulation of transcriptional activity by pml(B)(0.9412346)-role of erbb2 in signal transduction and oncology(B)(0.9662866)-the information processing pathway at the ifn beta enhancer(B)(0.985192) 8 ASAH1 8p22 0 2 3 31 347 5394 1650 0 0 0.384924623115578 Lysosome(K)(0.998375)-Metabolic pathways(K)(0.9989978)-Sphingolipid metabolism(K)(0.9982836)-Sphingosine 1-phosphate (S1P) pathway(N)(0.998406)-TNF receptor signaling pathway(N)(0.9965388)-TRAIL signaling pathway(N)(0.9986508)-phospholipids as signalling intermediaries(B)(0.9973596) 9 PIK3R1 5q13.1 0 0 0 2 129 4331 2377 0 1 0.131658291457286 Aldosterone-regulated sodium reabsorption(K)(0.9954958)-Alpha6Beta4Integrin(C)(0.9843938)-Amoebiasis(K)(0.9969912)-Androgen-mediated signaling(N)(0.965761)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9670606)-Apoptosis(K)(0.9829252)-B cell receptor signaling pathway(K)(0.990215)-Bacterial invasion of epithelial cells(K)(0.873816)-Cell surface interactions at the vascular wall(R)(0.9976786)-Chagas disease(K)(0.9932274)-Chemokine signaling pathway(K)(0.9965442)-EGFR1(C)(0.9981308)-Endothelins(N)(0.9876962)-EphrinB-EPHB pathway(N)(0.9666916)-ErbB signaling pathway(K)(0.972852)-Fc gamma R-mediated phagocytosis(K)(0.9943758)-Fc-epsilon receptor I signaling in mast cells(N)(0.979996)-Focal adhesion(K)(0.9963398)-Glypican pathway(N)(0.9961882)-Hypoxia response via HIF activation(P)(0.9593542)-IFN-gamma pathway(N)(0.9842468)-IL1-mediated signaling events(N)(0.9773908)-IL12-mediated signaling events(N)(0.9856526)-IL23-mediated signaling events(N)(0.9486728)-IL6-mediated signaling events(N)(0.9880482)-Insulin signaling pathway(K)(0.9969328)-Integrin signalling pathway(P)(0.9971678)-Jak-STAT signaling pathway(K)(0.9941378)-LPA receptor mediated events(N)(0.987337)-Leukocyte transendothelial migration(K)(0.9962492)-NOTCH(C)(0.9982136)-Natural killer cell mediated cytotoxicity(K)(0.9940688)-Nectin adhesion pathway(N)(0.9989052)-Neurotrophin signaling pathway(K)(0.9356714)-Pathways in cancer(K)(0.9985708)-Phosphatidylinositol signaling system(K)(0.9973432)-Plasma membrane estrogen receptor signaling(N)(0.9390422)-Progesterone-mediated oocyte maturation(K)(0.9953276)-Prostate cancer(K)(0.992806)-Proteogylcan syndecan-mediated signaling events(N)(0.9951898)-Reelin signaling pathway(N)(0.9855118)-Regulation of actin cytoskeleton(K)(0.9987564)-Signaling by Aurora kinases(N)(0.9498358)-Signaling by EGFR(R)(0.9625534)-Signaling by PDGF(R)(0.9341574)-Signaling events mediated by PTP1B(N)(0.9800586)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9088802)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9871012)-Signaling events mediated by the Hedgehog family(N)(0.9969844)-Signaling events regulated by Ret tyrosine kinase(N)(0.9917976)-Signalling by NGF(R)(0.997924)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9751954)-TCR signaling in naive CD4+ T cells(N)(0.9888564)-TGFBR(C)(0.9973872)-TNF receptor signaling pathway(N)(0.9951714)-Toll-like receptor signaling pathway(K)(0.9974948)-Type II diabetes mellitus(K)(0.9932052)-a6b1 and a6b4 Integrin signaling(N)(0.8834926)-actions of nitric oxide in the heart(B)(0.9937038)-b cell survival pathway(B)(0.9683524)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9453772)-ctcf: first multivalent nuclear factor(B)(0.9398286)-erk and pi-3 kinase are necessary for collagen binding in corneal epithelia(B)(0.8836224)-il-2 receptor beta chain in t cell activation(B)(0.9795104)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9534088)-mTOR signaling pathway(K)(0.9854046)-nfat and hypertrophy of the heart (B)(0.99367)-p75(NTR)-mediated signaling(N)(0.9971346)-rho cell motility signaling pathway(B)(0.8871858)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.98375)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9733788)-the co-stimulatory signal during t-cell activation(B)(0.8905806)-the igf-1 receptor and longevity(B)(0.977664)-thrombin signaling and protease-activated receptors(B)(0.9758772)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9574888) 10 CDH1 16q22.1 0 0 1 16 498 3930 1411 0 1 0.517587939698492 Adherens junction(K)(0.9973796)-Alzheimer disease-presenilin pathway(P)(0.997487)-Apoptosis(R)(0.9988512)-Bacterial invasion of epithelial cells(K)(0.9933744)-Cell adhesion molecules (CAMs)(K)(0.998923)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9932994)-Integrin cell surface interactions(R)(0.9984092)-Melanoma(K)(0.9800914)-Nectin adhesion pathway(N)(0.9624102)-Pathogenic Escherichia coli infection(K)(0.9964944)-Pathways in cancer(K)(0.998126)-Plasma membrane estrogen receptor signaling(N)(0.9979502)-Proteogylcan syndecan-mediated signaling events(N)(0.9990046)-Wnt signaling pathway(P)(0.9976318)-Wnt(C)(0.9976028)-a6b1 and a6b4 Integrin signaling(N)(0.9920294)-downregulated of mta-3 in er-negative breast tumors(B)(0.9966546)-tgf beta signaling pathway(B)(0.9910992) 11 ADRA1A 8p21.2 0 0 0 29 371 3800 662 0 0 0.402010050251256 Calcium signaling pathway(K)(0.9981202)-Class A/1 (Rhodopsin-like receptors)(R)(0.9988126)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9984312)-Neuroactive ligand-receptor interaction(K)(0.9995572)-Receptor-ligand complexes bind G proteins(R)(0.9918248)-Salivary secretion(K)(0.9979866)-Vascular smooth muscle contraction(K)(0.9967532) 12 CNGB1 16q13 0 0 1 11 472 3663 421 0 0 0.48643216080402 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.9980624)-Olfactory transduction(K)(0.999333)-Phototransduction(K)(0.9976946)-Visual signal transduction: Rods(N)(0.981607) 13 ACAT1 11q22.3 0 0 0 14 373 3424 1292 0 0 0.38894472361809 Butanoate metabolism(K)(0.806623)-Fatty acid metabolism(K)(0.995218)-Lysine degradation(K)(0.9979304)-Metabolic pathways(K)(0.999761)-Metabolism of amino acids(R)(0.9990072)-Metabolism of lipids and lipoproteins(R)(0.998426)-Pyruvate metabolism(K)(0.9973944)-Terpenoid backbone biosynthesis(K)(0.992716)-Tryptophan metabolism(K)(0.9961594) 14 TP53 17p13.1 0 0 0 7 411 3120 1976 0 1 0.420100502512563 () 15 POLR2C 16q13 0 0 2 10 480 2718 1635 0 0 0.494472361809045 DNA Repair(R)(0.9971662)-Formation and Maturation of mRNA Transcript(R)(0.99731)-HIV Life Cycle(R)(0.9977408)-Huntington's disease(K)(0.9990048)-Influenza Life Cycle(R)(0.997468)-Metabolic pathways(K)(0.9982384)-Purine metabolism(K)(0.9982178)-Pyrimidine metabolism(K)(0.9881194)-Regulatory RNA pathways(R)(0.9943654)-Transcription(R)(0.99484)-mRNA Processing(R)(0.9892928) 16 CDC42 1p36.12 0 0 0 2 257 2599 1987 0 0 0.260301507537688 Adherens junction(K)(0.9849092)-Axon guidance(K)(0.9981532)-Chemokine signaling pathway(K)(0.9981512)-EGFR1(C)(0.9985406)-Endocytosis(K)(0.9989804)-EphrinB-EPHB pathway(N)(0.9285934)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9930716)-Fc gamma R-mediated phagocytosis(K)(0.9937146)-Focal adhesion(K)(0.993893)-Glypican pathway(N)(0.999093)-GnRH signaling pathway(K)(0.9952552)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9897292)-Integrin signalling pathway(P)(0.9973726)-Leukocyte transendothelial migration(K)(0.9942318)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9922324)-MAPK signaling pathway(K)(0.9984442)-Nectin adhesion pathway(N)(0.9791684)-Neurotrophin signaling pathway(K)(0.9877526)-Pathogenic Escherichia coli infection(K)(0.9950394)-Pathways in cancer(K)(0.9972786)-Proteogylcan syndecan-mediated signaling events(N)(0.994908)-Regulation of actin cytoskeleton(K)(0.9981732)-Shigellosis(K)(0.9846614)-Signaling by EGFR(R)(0.972169)-Signaling by Rho GTPases(R)(0.9966886)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9611676)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9962848)-T cell receptor signaling pathway(K)(0.9727424)-TCR signaling in naive CD4+ T cells(N)(0.9884446)-Tight junction(K)(0.9986624)-p75(NTR)-mediated signaling(N)(0.9965528) 17 BIRC2 11q22.2 0 0 2 11 330 2379 1403 0 0 0.344723618090452 Apoptosis(K)(0.9955446)-Apoptosis(R)(0.9949044)-Focal adhesion(K)(0.9971292)-Glypican pathway(N)(0.9954206)-IL1-mediated signaling events(N)(0.9942484)-IL12-mediated signaling events(N)(0.9968776)-IL2-mediated signaling events(N)(0.993818)-IL23-mediated signaling events(N)(0.9911182)-LPA receptor mediated events(N)(0.9987806)-NOD-like receptor signaling pathway(K)(0.9961148)-Pathways in cancer(K)(0.9984198)-Signaling by Aurora kinases(N)(0.9625166)-Signaling events regulated by Ret tyrosine kinase(N)(0.992822)-TCR signaling in naive CD4+ T cells(N)(0.9891028)-TNF alpha/NF-kB(C)(0.9988978)-TNF receptor signaling pathway(N)(0.9958188)-Ubiquitin mediated proteolysis(K)(0.9989672)-keratinocyte differentiation(B)(0.9857642)-p75(NTR)-mediated signaling(N)(0.9976294) 18 PRKACB 1p31.1 0 0 0 3 175 2240 1927 0 0 0.178894472361809 Amoebiasis(K)(0.9965162)-Apoptosis(K)(0.9888504)-Calcium signaling pathway(K)(0.997514)-Chemokine signaling pathway(K)(0.9988556)-Dilated cardiomyopathy(K)(0.8761078)-Gap junction(K)(0.9938558)-Gastric acid secretion(K)(0.9916928)-GnRH signaling pathway(K)(0.986001)-Hedgehog signaling pathway(K)(0.9950692)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9972788)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.968475)-Insulin signaling pathway(K)(0.9982566)-Long-term potentiation(K)(0.9681902)-MAPK signaling pathway(K)(0.9989858)-Melanogenesis(K)(0.9797516)-Metabolism of lipids and lipoproteins(R)(0.9990934)-Olfactory transduction(K)(0.9975028)-Oocyte meiosis(K)(0.9927552)-Opioid Signalling(R)(0.9783744)-Prion diseases(K)(0.9876448)-Progesterone-mediated oocyte maturation(K)(0.9886812)-Salivary secretion(K)(0.9927462)-Signalling by NGF(R)(0.9973672)-Taste transduction(K)(0.9919846)-Vascular smooth muscle contraction(K)(0.9957924)-Vasopressin-regulated water reabsorption(K)(0.990323)-Vibrio cholerae infection(K)(0.9968134)-Wnt signaling pathway(K)(0.9968028)-p75(NTR)-mediated signaling(N)(0.9972444) 19 PAFAH1B1 17p13.3 0 0 2 9 432 2019 1328 2e-04 0 0.445226130653266 Ether lipid metabolism(K)(0.9805622)-G2/M Transition(R)(0.9973044)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9953418)-M Phase(R)(0.9982692)-Metabolic pathways(K)(0.998792)-Reelin signaling pathway(N)(0.9967802) 20 CX3CL1 16q13 0 0 2 10 481 1889 593 0.0015 0 0.495477386934673 Chemokine signaling pathway(K)(0.9984622)-Class A/1 (Rhodopsin-like receptors)(R)(0.9991914)-Cytokine-cytokine receptor interaction(K)(0.9983816)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9974792) 21 CTNNB1 3p22.1 0 0 0 0 165 1823 1767 0.0039 1 0.165829145728643 Adherens junction(K)(0.9939056)-Alzheimer disease-presenilin pathway(P)(0.9970372)-Androgen-mediated signaling(N)(0.947867)-AndrogenReceptor(C)(0.994798)-Angiogenesis(P)(0.9883404)-Apoptosis(R)(0.9976148)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.991535)-Bacterial invasion of epithelial cells(K)(0.9926324)-Focal adhesion(K)(0.9978536)-FoxO family signaling(N)(0.9915314)-Glypican pathway(N)(0.9920548)-IFN-gamma pathway(N)(0.9957926)-Leukocyte transendothelial migration(K)(0.9950944)-Melanogenesis(K)(0.9857958)-Nectin adhesion pathway(N)(0.991961)-Pathogenic Escherichia coli infection(K)(0.9927604)-Pathways in cancer(K)(0.998927)-Plasma membrane estrogen receptor signaling(N)(0.9850306)-Presenilin action in Notch and Wnt signaling(N)(0.9539824)-Prostate cancer(K)(0.9866906)-Proteogylcan syndecan-mediated signaling events(N)(0.9970422)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9804306)-TGFBR(C)(0.9977478)-Tight junction(K)(0.9993428)-Wnt signaling pathway(K)(0.9949056)-Wnt signaling pathway(P)(0.9973692)-Wnt(C)(0.9948154)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9825088)-multi-step regulation of transcription by pitx2(B)(0.9780572)-p53 pathway feedback loops 2(P)(0.9655014)-segmentation clock(B)(0.9850228) 22 TUBB3 16q24.3 0 0 1 11 459 1716 557 0.0066 0 0.473366834170854 Gap junction(K)(0.9948054)-Huntington disease(P)(0.9984782)-Metabolism of proteins(R)(0.9990428)-Pathogenic Escherichia coli infection(K)(0.9954284)-Phagosome(K)(0.9993598) 23 ENO1 1p36.23 0 0 0 1 241 1681 1340 0.0078 0 0.24321608040201 Glucose Regulation of Insulin Secretion(R)(0.997668)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9979738)-Metabolic pathways(K)(0.998407)-Metabolism of carbohydrates(R)(0.9983442)-RNA degradation(K)(0.9982668) 24 SNRPD3 22q11.23 0 0 2 0 262 1585 502 0.018 0 0.265326633165829 Formation and Maturation of mRNA Transcript(R)(0.9985614)-Influenza Life Cycle(R)(0.9987702)-Metabolism of non-coding RNA(R)(0.996969)-Spliceosome(K)(0.9988902)-Systemic lupus erythematosus(K)(0.999557) 25 MAP2K4 17p12 0 0 0 26 448 1554 1407 0.0201 1 0.476381909547739 BMP receptor signaling(N)(0.995036)-Cellular roles of Anthrax toxin(N)(0.9852768)-Chagas disease(K)(0.9970044)-EphrinB-EPHB pathway(N)(0.9851722)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.997381)-ErbB signaling pathway(K)(0.9940844)-FAS signaling pathway (CD95)(N)(0.9758102)-FAS signaling pathway(P)(0.9911726)-Fc epsilon RI signaling pathway(K)(0.9787938)-Fc-epsilon receptor I signaling in mast cells(N)(0.9862812)-Glypican pathway(N)(0.9975426)-GnRH signaling pathway(K)(0.9954632)-IFN-gamma pathway(N)(0.9929)-IL1-mediated signaling events(N)(0.9913128)-IL6-mediated signaling events(N)(0.995266)-Integrin signalling pathway(P)(0.9984392)-MAPK signaling pathway(K)(0.9992908)-Oxidative stress response(P)(0.9747418)-Plasma membrane estrogen receptor signaling(N)(0.9920014)-Proteogylcan syndecan-mediated signaling events(N)(0.998976)-Sphingosine 1-phosphate (S1P) pathway(N)(0.994611)-TCR signaling in naive CD4+ T cells(N)(0.9948234)-TNF receptor signaling pathway(N)(0.9973604)-TRAIL signaling pathway(N)(0.9903062)-Toll-like receptor signaling pathway(K)(0.9989236)-VEGFR3 signaling in lymphatic endothelium(N)(0.9827992)-keratinocyte differentiation(B)(0.9846296)-map kinase inactivation of smrt corepressor(B)(0.9893108)-p38 mapk signaling pathway(B)(0.9891976)-t cell receptor signaling pathway(B)(0.9947656)-toll-like receptor pathway(B)(0.9761684) 26 UBE2G1 17p13.2 0 0 0 6 429 1511 408 0.0256 0 0.437185929648241 Parkinson's disease(K)(0.9972154)-Protein processing in endoplasmic reticulum(K)(0.998764)-Ubiquitin mediated proteolysis(K)(0.9978786) 27 ADCY7 16q12.1 0 0 2 9 438 1402 1202 0.0418 0 0.451256281407035 5HT3 type receptor mediated signaling pathway(P)(0.895392)-Calcium signaling pathway(K)(0.9984632)-Chemokine signaling pathway(K)(0.9986142)-Dilated cardiomyopathy(K)(0.995439)-Endothelin signaling pathway(P)(0.9449706)-Endothelins(N)(0.9950704)-Gap junction(K)(0.995647)-Gastric acid secretion(K)(0.99121)-GnRH signaling pathway(K)(0.9941502)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.998245)-LPA receptor mediated events(N)(0.9943408)-Melanogenesis(K)(0.9935794)-Oocyte meiosis(K)(0.9956814)-Opioid Signalling(R)(0.9825892)-Pancreatic secretion(K)(0.998082)-Progesterone-mediated oocyte maturation(K)(0.997058)-Purine metabolism(K)(0.9964048)-Salivary secretion(K)(0.9913158)-Signalling by NGF(R)(0.9993192)-Vascular smooth muscle contraction(K)(0.9983104) 28 AKT1 14q32.33 0 0 4 0 151 1276 2455 0.0676 1 0.155778894472362 Adipocytokine signaling pathway(K)(0.9939484)-Alpha6Beta4Integrin(C)(0.9807912)-Androgen-mediated signaling(N)(0.9538924)-AndrogenReceptor(C)(0.9967436)-Angiogenesis(P)(0.9648246)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9796914)-Apoptosis(K)(0.9835996)-Apoptosis(R)(0.9989482)-B cell receptor signaling pathway(K)(0.9784736)-Chagas disease(K)(0.9840258)-Chemokine signaling pathway(K)(0.9952116)-EGFR1(C)(0.9976858)-Endothelins(N)(0.9867452)-ErbB signaling pathway(K)(0.985904)-FAS signaling pathway(P)(0.9376538)-FOXA transcription factor networks(N)(0.9651204)-Fc gamma R-mediated phagocytosis(K)(0.9959132)-Fc-epsilon receptor I signaling in mast cells(N)(0.9824452)-Focal adhesion(K)(0.9986446)-FoxO family signaling(N)(0.9648274)-Glypican pathway(N)(0.9914112)-Huntington disease(P)(0.9969292)-Hypoxia response via HIF activation(P)(0.9443724)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9877176)-IFN-gamma pathway(N)(0.958046)-IL2-mediated signaling events(N)(0.9203214)-IL6-mediated signaling events(N)(0.979733)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9640012)-Insulin signaling pathway(K)(0.997165)-Integrins in angiogenesis(N)(0.985346)-Jak-STAT signaling pathway(K)(0.995664)-MAPK signaling pathway(K)(0.9978872)-Metabolism of nitric oxide(R)(0.9703502)-Nectin adhesion pathway(N)(0.9865108)-Neurotrophin signaling pathway(K)(0.9428166)-Pathways in cancer(K)(0.9997586)-Plasma membrane estrogen receptor signaling(N)(0.9671338)-Progesterone-mediated oocyte maturation(K)(0.9891708)-Prostate cancer(K)(0.9865386)-Proteogylcan syndecan-mediated signaling events(N)(0.997432)-Reelin signaling pathway(N)(0.9565542)-Regulation of Telomerase(N)(0.9953896)-Regulation of beta-cell development(R)(0.9912334)-Retinoic acid receptors-mediated signaling(N)(0.9415496)-Signaling by Wnt(R)(0.8947518)-Signaling events mediated by PTP1B(N)(0.9572576)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9041758)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9553902)-Signaling events mediated by the Hedgehog family(N)(0.9946856)-Signalling by NGF(R)(0.9947238)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9859076)-TCR signaling in naive CD4+ T cells(N)(0.971477)-TNF alpha/NF-kB(C)(0.9978568)-TNF receptor signaling pathway(N)(0.9842132)-Thromboxane A2 receptor signaling(N)(0.9870914)-Tight junction(K)(0.9976506)-Toll-like receptor signaling pathway(K)(0.9945348)-Wnt(C)(0.9979582)-a6b1 and a6b4 Integrin signaling(N)(0.9459554)-hypoxia and p53 in the cardiovascular system(B)(0.9737014)-mTOR signaling pathway(K)(0.9782782)-p53 pathway(P)(0.9633046)-p75(NTR)-mediated signaling(N)(0.9983048)-regulation of eif2(B)(0.9888324) 29 CCNH 5q14.3 0 0 0 1 157 1236 668 0.0751 0 0.158793969849246 AndrogenReceptor(C)(0.9976178)-Cell cycle(K)(0.9988024)-DNA Repair(R)(0.9991294)-Formation and Maturation of mRNA Transcript(R)(0.99913)-G1/S Transition(R)(0.9934938)-G2/M Transition(R)(0.998511)-HIV Life Cycle(R)(0.9930374)-Nucleotide excision repair(K)(0.9898934)-Retinoic acid receptors-mediated signaling(N)(0.993994)-S Phase(R)(0.8653288)-Transcription(R)(0.99445)-il-2 receptor beta chain in t cell activation(B)(0.9944354)-mRNA Processing(R)(0.983051) 30 PNMT 17q12 0 80 33 1 140 1224 1128 0.0759 0 0.255276381909548 Metabolic pathways(K)(0.9992132)-Tyrosine metabolism(K)(0.9977466) 31 FYN 6q21 0 0 5 5 227 1169 1620 0.0857 0 0.238190954773869 Adherens junction(K)(0.9963836)-Alpha-synuclein signaling(N)(0.962813)-Alpha6Beta4Integrin(C)(0.9923674)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9551912)-Axon guidance(K)(0.9982964)-BMP receptor signaling(N)(0.9959888)-Cell surface interactions at the vascular wall(R)(0.9961404)-Fc epsilon RI signaling pathway(K)(0.983781)-Fc-epsilon receptor I signaling in mast cells(N)(0.9673376)-Focal adhesion(K)(0.9970924)-Glypican pathway(N)(0.9922202)-Host Interactions of HIV factors(R)(0.9982856)-IFN-gamma pathway(N)(0.9933118)-IL1-mediated signaling events(N)(0.9944146)-IL2-mediated signaling events(N)(0.989188)-Integrin signalling pathway(P)(0.9976374)-KitReceptor(C)(0.9802518)-Natural killer cell mediated cytotoxicity(K)(0.996296)-Nectin adhesion pathway(N)(0.97719)-Parkinson disease(P)(0.9943264)-Pathogenic Escherichia coli infection(K)(0.9974272)-Plasma membrane estrogen receptor signaling(N)(0.987666)-Prion diseases(K)(0.9968352)-Proteogylcan syndecan-mediated signaling events(N)(0.9974098)-Reelin signaling pathway(N)(0.9867436)-Signaling events mediated by PTP1B(N)(0.9930608)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9895868)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9774438)-T cell receptor signaling pathway(K)(0.9832994)-TCR signaling in naive CD4+ T cells(N)(0.9738682)-TNF receptor signaling pathway(N)(0.9922852)-TRAIL signaling pathway(N)(0.9597566)-Thromboxane A2 receptor signaling(N)(0.989814)-Viral myocarditis(K)(0.9931036) 32 EPHX2 8p21.1 0 0 1 30 348 1100 1176 0.1019 0 0.380904522613065 Arachidonic acid metabolism(K)(0.998311)-Metabolic pathways(K)(0.9989218)-Peroxisome(K)(0.9984946) 33 DRD2 11q23.2 0 0 0 14 359 1031 554 0.1179 0 0.374874371859297 Class A/1 (Rhodopsin-like receptors)(R)(0.9980602)-Gap junction(K)(0.9962054)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9973752)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9967274)-Neuroactive ligand-receptor interaction(K)(0.9982454)-Receptor-ligand complexes bind G proteins(R)(0.9952892)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9932128) 34 H2AFX 11q23.3 0 0 2 12 349 990 236 0.1269 0 0.364824120603015 DNA Repair(R)(0.9976758)-Systemic lupus erythematosus(K)(0.9981514)-Telomere Maintenance(R)(0.9982194) 35 PRKX 23p22.33 0 0 0 6 168 967 1639 0.1309 0 0.174874371859296 Amoebiasis(K)(0.9979076)-Apoptosis(K)(0.9976066)-Calcium signaling pathway(K)(0.997528)-Chemokine signaling pathway(K)(0.9969762)-Dilated cardiomyopathy(K)(0.8680316)-Gap junction(K)(0.995164)-Gastric acid secretion(K)(0.992861)-GnRH signaling pathway(K)(0.9877068)-Hedgehog signaling pathway(K)(0.991205)-Insulin signaling pathway(K)(0.9977106)-Long-term potentiation(K)(0.9766052)-MAPK signaling pathway(K)(0.9989386)-Melanogenesis(K)(0.9836738)-Olfactory transduction(K)(0.9995194)-Oocyte meiosis(K)(0.997315)-Prion diseases(K)(0.9868736)-Progesterone-mediated oocyte maturation(K)(0.9841818)-Salivary secretion(K)(0.9984076)-Taste transduction(K)(0.9969598)-Vascular smooth muscle contraction(K)(0.997501)-Vasopressin-regulated water reabsorption(K)(0.9956478)-Vibrio cholerae infection(K)(0.996215)-Wnt signaling pathway(K)(0.998838) 36 AP1G1 16q22.3 0 0 0 17 534 956 264 0.131 0 0.553768844221106 Host Interactions of HIV factors(R)(0.9988036)-Lysosome(K)(0.9991354)-Membrane Trafficking(R)(0.9970952) 37 INS 11p15.5 0 0 0 0 172 945 1454 0.131 0 0.17286432160804 Aldosterone-regulated sodium reabsorption(K)(0.9932228)-Endothelins(N)(0.9900878)-FOXA transcription factor networks(N)(0.9754412)-Glucose Regulation of Insulin Secretion(R)(0.9974976)-Glypican pathway(N)(0.9983314)-IFN-gamma pathway(N)(0.9964292)-Insulin Synthesis and Secretion(R)(0.9982766)-Insulin signaling pathway(K)(0.996885)-Maturity onset diabetes of the young(K)(0.9857078)-Oocyte meiosis(K)(0.9979322)-Plasma membrane estrogen receptor signaling(N)(0.9947108)-Progesterone-mediated oocyte maturation(K)(0.9884454)-Prostate cancer(K)(0.9954134)-Proteogylcan syndecan-mediated signaling events(N)(0.9982116)-Regulation of actin cytoskeleton(K)(0.999301)-Regulation of autophagy(K)(0.9978702)-Regulation of beta-cell development(R)(0.9816416)-Signaling by Insulin receptor(R)(0.9713956)-Signaling events mediated by PTP1B(N)(0.9967502)-TRAIL signaling pathway(N)(0.9978178)-Type I diabetes mellitus(K)(0.990261)-Type II diabetes mellitus(K)(0.9839308)-growth hormone signaling pathway(B)(0.9856294)-mTOR signaling pathway(K)(0.9912084) 38 PPP2CB 8p12 0 2 3 32 334 934 1342 0.1317 0 0.37286432160804 Chagas disease(K)(0.9977488)-EGF receptor signaling pathway(P)(0.9953772)-FGF signaling pathway(P)(0.9928214)-Glypican pathway(N)(0.9966958)-IFN-gamma pathway(N)(0.9990852)-Long-term depression(K)(0.997301)-M Phase(R)(0.9991426)-Oocyte meiosis(K)(0.9890678)-Opioid Signalling(R)(0.995475)-Signaling by Wnt(R)(0.984556)-Signalling by NGF(R)(0.999236)-TGF-beta signaling pathway(K)(0.9982036)-Tight junction(K)(0.998878)-Wnt signaling pathway(K)(0.996413)-Wnt signaling pathway(P)(0.9982816) 39 RHOBTB2 8p21.3 0 0 1 32 368 886 261 0.1438 0 0.403015075376884 Signaling by Rho GTPases(R)(0.9984696)-Ubiquitin mediated proteolysis(K)(0.9994074) 40 ENO3 17p13.2 0 0 0 5 407 862 1275 0.1492 0 0.414070351758794 Glucose Regulation of Insulin Secretion(R)(0.9967352)-Metabolic pathways(K)(0.9992618)-Metabolism of carbohydrates(R)(0.9980888)-RNA degradation(K)(0.997622) 41 KRAS 12p12.1 0 3 4 1 84 835 1948 0.1563 1 0.0924623115577889 Aldosterone-regulated sodium reabsorption(K)(0.9910378)-Axon guidance(K)(0.9978568)-B cell receptor signaling pathway(K)(0.980909)-Cell surface interactions at the vascular wall(R)(0.9980888)-Chemokine signaling pathway(K)(0.997319)-Dorso-ventral axis formation(K)(0.99252)-EGF receptor signaling pathway(P)(0.9307666)-EGFR1(C)(0.995979)-EphrinB-EPHB pathway(N)(0.928476)-ErbB signaling pathway(K)(0.9864224)-FGF signaling pathway(P)(0.9161716)-Gap junction(K)(0.9938634)-Glypican pathway(N)(0.9975818)-GnRH signaling pathway(K)(0.9917984)-IL2-mediated signaling events(N)(0.9953778)-Insulin signaling pathway(K)(0.9976284)-Integrin signalling pathway(P)(0.9976398)-Long-term depression(K)(0.9898916)-Long-term potentiation(K)(0.9810384)-MAPK signaling pathway(K)(0.9984156)-Natural killer cell mediated cytotoxicity(K)(0.9947438)-Neurotrophin signaling pathway(K)(0.9949662)-Pathways in cancer(K)(0.9993742)-Plasma membrane estrogen receptor signaling(N)(0.9981088)-Progesterone-mediated oocyte maturation(K)(0.989749)-Prostate cancer(K)(0.9818426)-Regulation of actin cytoskeleton(K)(0.9981374)-Signaling by EGFR(R)(0.985331)-Signaling by PDGF(R)(0.9875146)-Signalling by NGF(R)(0.9975704)-T cell receptor signaling pathway(K)(0.9777864)-TCR signaling in naive CD4+ T cells(N)(0.9882712)-TRAIL signaling pathway(N)(0.9938828)-Tight junction(K)(0.998464)-VEGF signaling pathway(K)(0.9691234)-p53 pathway feedback loops 2(P)(0.9786268)-p75(NTR)-mediated signaling(N)(0.9946556)-telomeres telomerase cellular aging and immortality(B)(0.9787526) 42 IKBKB 8p11.21 0 9 33 6 120 778 1785 0.1708 0 0.168844221105528 Adipocytokine signaling pathway(K)(0.9978166)-Apoptosis signaling pathway(P)(0.8842778)-Apoptosis(K)(0.9856688)-B cell receptor signaling pathway(K)(0.9799248)-Chagas disease(K)(0.9906886)-Chemokine signaling pathway(K)(0.9986402)-Cytosolic DNA-sensing pathway(K)(0.9938866)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9974148)-Fc-epsilon receptor I signaling in mast cells(N)(0.9871214)-Glypican pathway(N)(0.9984382)-IL1-mediated signaling events(N)(0.96399)-IL12-mediated signaling events(N)(0.9932278)-IL2-mediated signaling events(N)(0.9937862)-IL23-mediated signaling events(N)(0.9867878)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.996688)-Insulin signaling pathway(K)(0.997126)-Interleukin signaling pathway(P)(0.9850382)-LPA receptor mediated events(N)(0.9964172)-MAPK signaling pathway(K)(0.9975188)-NOD-like receptor signaling pathway(K)(0.9912434)-Neurotrophin signaling pathway(K)(0.9802282)-Pathways in cancer(K)(0.9990298)-Prostate cancer(K)(0.9925602)-RIG-I-like receptor signaling pathway(K)(0.9971576)-Shigellosis(K)(0.99633)-Signaling by Aurora kinases(N)(0.954217)-Signaling events regulated by Ret tyrosine kinase(N)(0.989294)-Signalling by NGF(R)(0.997149)-T cell receptor signaling pathway(K)(0.9922314)-TCR signaling in naive CD4+ T cells(N)(0.9840386)-TNF alpha/NF-kB(C)(0.9980388)-TNF receptor signaling pathway(N)(0.9899358)-Toll-like receptor signaling pathway(K)(0.991143)-Type II diabetes mellitus(K)(0.9785222)-bone remodeling(B)(0.9299414)-double stranded rna induced gene expression(B)(0.978008)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9751588)-keratinocyte differentiation(B)(0.9645516)-lectin induced complement pathway(B)(0.9746494)-p75(NTR)-mediated signaling(N)(0.9977576)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9549292)-trefoil factors initiate mucosal healing(B)(0.9665148) 43 OR10S1 11q24.1 0 0 0 12 362 771 413 0.1708 0 0.375879396984925 Olfactory transduction(K)(0.9988398) 44 KARS 16q23.1 0 0 1 8 498 762 44 0.1708 0 0.509547738693467 Aminoacyl-tRNA biosynthesis(K)(0.9996512)-tRNA Aminoacylation(R)(0.9964748) 45 CASP3 4q35.1 0 0 0 3 148 759 1908 0.1708 0 0.151758793969849 Alpha6Beta4Integrin(C)(0.9931204)-Alzheimer's disease(K)(0.9935534)-Amoebiasis(K)(0.9954484)-Amyotrophic lateral sclerosis (ALS)(K)(0.9940132)-Apoptosis signaling pathway(P)(0.9695724)-Apoptosis(K)(0.9878322)-Apoptosis(R)(0.9982042)-BMP receptor signaling(N)(0.9937174)-Endothelins(N)(0.9892302)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9938792)-FAS signaling pathway (CD95)(N)(0.973324)-FAS signaling pathway(P)(0.9879606)-Glypican pathway(N)(0.9988876)-Huntington disease(P)(0.9977224)-Huntington's disease(K)(0.9984518)-IFN-gamma pathway(N)(0.9947516)-IL1-mediated signaling events(N)(0.9888982)-LPA receptor mediated events(N)(0.990004)-MAPK signaling pathway(K)(0.9981156)-Natural killer cell mediated cytotoxicity(K)(0.9970264)-Parkinson's disease(K)(0.9963966)-Pathways in cancer(K)(0.9987906)-Plasma membrane estrogen receptor signaling(N)(0.9902474)-Proteogylcan syndecan-mediated signaling events(N)(0.9972842)-Signalling by NGF(R)(0.9978066)-TNF alpha/NF-kB(C)(0.9990136)-TNF receptor signaling pathway(N)(0.9935256)-Viral myocarditis(K)(0.9975172)-a6b1 and a6b4 Integrin signaling(N)(0.9748766)-b cell survival pathway(B)(0.9810546)-granzyme a mediated apoptosis pathway(B)(0.9752088)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9559594)-internal ribosome entry pathway(B)(0.9800156)-p53 signaling pathway(K)(0.997149)-p75(NTR)-mediated signaling(N)(0.9964542)-trefoil factors initiate mucosal healing(B)(0.8749376) 46 PTEN 10q23.31 0 0 0 16 145 704 1456 0.1869 1 0.161809045226131 Endothelins(N)(0.995834)-Focal adhesion(K)(0.996704)-Glypican pathway(N)(0.9943558)-IFN-gamma pathway(N)(0.9982426)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.99655)-Inositol phosphate metabolism(K)(0.991249)-Insulin/IGF pathway-protein kinase B signaling cascade(P)(0.8070242)-Nectin adhesion pathway(N)(0.9971452)-PI3 kinase pathway(P)(0.9643476)-Pathways in cancer(K)(0.9980162)-Phosphatidylinositol signaling system(K)(0.9984036)-Prostate cancer(K)(0.995049)-Proteogylcan syndecan-mediated signaling events(N)(0.9980214)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9913416)-Signalling by NGF(R)(0.9989078)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9936224)-TCR signaling in naive CD4+ T cells(N)(0.9963958)-TCR signaling(R)(0.9037024)-TRAIL signaling pathway(N)(0.9969244)-Tight junction(K)(0.999012)-ctcf: first multivalent nuclear factor(B)(0.9934376)-p53 pathway(P)(0.8611332)-p53 signaling pathway(K)(0.9973122)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9928064) 47 ALDH3A1 17p11.2 0 0 5 4 336 698 1169 0.1869 0 0.346733668341709 Drug metabolism - cytochrome P450(K)(0.9987932)-Histidine metabolism(K)(0.9978406)-Metabolic pathways(K)(0.999608)-Metabolism of xenobiotics by cytochrome P450(K)(0.9988016) 48 GALNTL6 4q34.1 0 0 1 4 161 688 1121 0.1869 0 0.166834170854271 Metabolic pathways(K)(0.9985838) 49 MYH3 17p13.1 0 0 2 7 440 677 513 0.1869 0 0.451256281407035 Muscle contraction(R)(0.9953982)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9969986)-Tight junction(K)(0.9986188)-Viral myocarditis(K)(0.9978764)-Wnt signaling pathway(P)(0.99823) 50 RPA1 17p13.3 0 0 0 8 427 676 298 0.1869 0 0.437185929648241 Cell Cycle Checkpoints(R)(0.9984392)-DNA Repair(R)(0.9987776)-DNA replication(K)(0.979966)-G1/S Transition(R)(0.9918904)-Homologous recombination(K)(0.9948076)-Mismatch repair(K)(0.994041)-Nucleotide excision repair(K)(0.995791)-S Phase(R)(0.9910268)-Telomere Maintenance(R)(0.9991624)-atm signaling pathway(B)(0.9856702)-hypoxia and p53 in the cardiovascular system(B)(0.9964164) 51 BCAR1 16q23.1 0 0 1 12 494 665 1128 0.1886 0 0.509547738693467 Bacterial invasion of epithelial cells(K)(0.9915436)-Chemokine signaling pathway(K)(0.9979746)-EGFR1(C)(0.997856)-Endothelins(N)(0.9956014)-EphrinA-EPHA pathway(N)(0.9663414)-Focal adhesion(K)(0.9961982)-Formation of Platelet plug(R)(0.994874)-Integrin cell surface interactions(R)(0.9937904)-Integrin signalling pathway(P)(0.9991912)-Integrins in angiogenesis(N)(0.9934252)-LPA receptor mediated events(N)(0.9965296)-Leukocyte transendothelial migration(K)(0.9972536)-Nectin adhesion pathway(N)(0.9939746)-Plasma membrane estrogen receptor signaling(N)(0.999195)-Regulation of actin cytoskeleton(K)(0.9977042)-Signaling by PDGF(R)(0.9942198)-Signaling events mediated by PRL(N)(0.990367)-Signaling events mediated by PTP1B(N)(0.99689)-Signaling events regulated by Ret tyrosine kinase(N)(0.9936524)-Sphingosine 1-phosphate (S1P) pathway(N)(0.997725)-integrin signaling pathway(B)(0.9919952)-vegf hypoxia and angiogenesis(B)(0.9851234) 52 GNB1 1p36.33 0 0 0 2 199 647 1721 0.1927 0 0.202010050251256 Androgen-mediated signaling(N)(0.9635244)-Chemokine signaling pathway(K)(0.9981498)-Formation of Platelet plug(R)(0.9991362)-Glypican pathway(N)(0.9990144)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9966948)-LPA receptor mediated events(N)(0.9892304)-Olfactory Signaling Pathway(R)(0.9990996)-Opioid Signalling(R)(0.9954774)-Phototransduction(K)(0.9940712)-Plasma membrane estrogen receptor signaling(N)(0.9901376)-Proteogylcan syndecan-mediated signaling events(N)(0.999461)-Receptor-ligand complexes bind G proteins(R)(0.9972028)-Signaling events mediated by HDAC Class I(N)(0.9968424)-Signaling events mediated by the Hedgehog family(N)(0.9962876)-Taste transduction(K)(0.9956418)-Thromboxane A2 receptor signaling(N)(0.9938582)-Visual signal transduction: Rods(N)(0.9683674)-Wnt signaling pathway(P)(0.9977866)-actions of nitric oxide in the heart(B)(0.994914)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9213398)-bioactive peptide induced signaling pathway(B)(0.9494586)-chrebp regulation by carbohydrates and camp(B)(0.992637)-corticosteroids and cardioprotection(B)(0.9720662)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9806118)-how progesterone initiates the oocyte maturation(B)(0.9910964)-ion channels and their functional role in vascular endothelium(B)(0.992199)-phospholipids as signalling intermediaries(B)(0.9902292)-pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase(B)(0.9905686)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.963686)-regulation of spermatogenesis by crem(B)(0.9683342)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9739594)-thrombin signaling and protease-activated receptors(B)(0.9885796)-visual signal transduction(B)(0.9666482) 53 SNW1 14q24.3 0 0 0 2 207 629 366 0.195 0 0.210050251256281 Generic Transcription Pathway(R)(0.9979922)-NOTCH(C)(0.9976464)-Notch signaling pathway(K)(0.997764)-Spliceosome(K)(0.9992752)-TGFBR(C)(0.9983158)-control of gene expression by vitamin d receptor(B)(0.9929016) 54 EIF4EBP1 8p12 0 39 39 8 168 628 1149 0.195 0 0.255276381909548 Acute myeloid leukemia(K)(0.9963028)-BMP receptor signaling(N)(0.9973528)-Endothelins(N)(0.9943478)-ErbB signaling pathway(K)(0.9957458)-Glypican pathway(N)(0.9932298)-IFN-gamma pathway(N)(0.9993018)-IL1-mediated signaling events(N)(0.9974142)-Insulin signaling pathway(K)(0.9978574)-Metabolism of proteins(R)(0.9976762)-Plasma membrane estrogen receptor signaling(N)(0.9939446)-Proteogylcan syndecan-mediated signaling events(N)(0.9990878)-Signaling by Insulin receptor(R)(0.9776478)-TNF receptor signaling pathway(N)(0.9980178)-TRAIL signaling pathway(N)(0.9952588)-mTOR signaling pathway(K)(0.9936938)-p53 pathway by glucose deprivation(P)(0.9885476)-regulation of eif-4e and p70s6 kinase(B)(0.9585306) 55 LPL 8p21.3 0 1 2 30 354 611 385 0.1981 0 0.38894472361809 Alzheimer's disease(K)(0.9988614)-Glycerolipid metabolism(K)(0.9992392)-Metabolism of lipids and lipoproteins(R)(0.998831)-PPAR signaling pathway(K)(0.9983966)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9972814) 56 CSF2RA 23p22.33 0 0 1 10 233 594 644 0.203 0 0.245226130653266 Cytokine-cytokine receptor interaction(K)(0.998679)-Hematopoietic cell lineage(K)(0.997646)-Jak-STAT signaling pathway(K)(0.9976204)-Pathways in cancer(K)(0.9996504) 57 RB1 13q14.2 0 0 1 16 310 573 1060 0.2095 1 0.328643216080402 AndrogenReceptor(C)(0.9965036)-Bladder cancer(K)(0.9745534)-Cell cycle(K)(0.9980458)-DNA Replication(R)(0.962279)-FAS signaling pathway (CD95)(N)(0.9831288)-FOXM1 transcription factor network(N)(0.9949978)-G1/S Transition(R)(0.9910938)-Glioma(K)(0.9940174)-ID(C)(0.995856)-Pathways in cancer(K)(0.9969366)-Prostate cancer(K)(0.9954982)-Regulation of retinoblastoma protein(N)(0.9962854)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9984368)-TGFBR(C)(0.9981448)-TNF receptor signaling pathway(N)(0.9971056)-TRAIL signaling pathway(N)(0.996355)-il-2 receptor beta chain in t cell activation(B)(0.9943902)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.996517)-rb tumor suppressor/checkpoint signaling in response to dna damage(B)(0.8509722)-regulation of transcriptional activity by pml(B)(0.9848562)-telomeres telomerase cellular aging and immortality(B)(0.9922462)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9880252) 58 PRSS1 7q34 0 0 4 1 127 564 367 0.2098 0 0.132663316582915 Neuroactive ligand-receptor interaction(K)(0.9993614)-Pancreatic secretion(K)(0.9978004) 59 PAK1 11q14.1 0 27 43 5 123 555 1656 0.2112 0 0.198994974874372 Alpha6Beta4Integrin(C)(0.9950152)-Angiogenesis(P)(0.9906574)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9880156)-Axon guidance(K)(0.9987018)-BMP receptor signaling(N)(0.998239)-Chemokine signaling pathway(K)(0.9965)-EGFR1(C)(0.997753)-EphrinB-EPHB pathway(N)(0.9533724)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9971486)-ErbB signaling pathway(K)(0.9840466)-Fc gamma R-mediated phagocytosis(K)(0.9975538)-Focal adhesion(K)(0.9981066)-Glypican pathway(N)(0.996503)-IFN-gamma pathway(N)(0.9977154)-IL1-mediated signaling events(N)(0.9935182)-MAPK signaling pathway(K)(0.999158)-Natural killer cell mediated cytotoxicity(K)(0.9986326)-Plasma membrane estrogen receptor signaling(N)(0.9879818)-Proteogylcan syndecan-mediated signaling events(N)(0.995196)-Regulation of actin cytoskeleton(K)(0.997761)-Renal cell carcinoma(K)(0.9933802)-Signaling by Aurora kinases(N)(0.9783736)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9513186)-Sphingosine 1-phosphate (S1P) pathway(N)(0.99584)-T cell receptor signaling pathway(K)(0.9944796)-TNF receptor signaling pathway(N)(0.9960876)-agrin in postsynaptic differentiation(B)(0.9907502)-fas signaling pathway (cd95)(B)(0.9436578)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9874594)-influence of ras and rho proteins on g1 to s transition(B)(0.9643594)-rac1 cell motility signaling pathway(B)(0.8902994)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.984175) 60 ABCC11 16q12.1 0 1 1 10 426 540 44 0.2161 0 0.440201005025126 ABC transporters(K)(0.9986698) 61 STX8 17p13.1 0 0 1 11 478 530 73 0.2181 0 0.492462311557789 Botulinum neurotoxicity(R)(0.9959524)-Membrane Trafficking(R)(0.998934)-SNARE interactions in vesicular transport(K)(0.9971412) 62 NCOR1 17p11.2 0 0 0 14 433 497 772 0.2329 0 0.449246231155779 Glypican pathway(N)(0.9973194)-Huntington disease(P)(0.9991102)-IFN-gamma pathway(N)(0.998559)-NOTCH(C)(0.997359)-NR transcription pathway(R)(0.9968304)-Signaling events mediated by HDAC Class I(N)(0.9968352)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9915504) 63 ERBB2 17q12 0 83 35 1 143 485 739 0.2341 1 0.263316582914573 Adherens junction(K)(0.9990918)-Alpha6Beta4Integrin(C)(0.997947)-Bladder cancer(K)(0.9759026)-Calcium signaling pathway(K)(0.9990682)-EGF receptor signaling pathway(P)(0.9969408)-ErbB signaling pathway(K)(0.997149)-Focal adhesion(K)(0.997417)-Pathways in cancer(K)(0.9994742)-Prostate cancer(K)(0.9979654)-a6b1 and a6b4 Integrin signaling(N)(0.995837) 64 PLG 6q26 0 0 0 2 208 480 854 0.2341 0 0.21105527638191 Angiopoietin receptor Tie2-mediated signaling(N)(0.9956436)-Complement and coagulation cascades(K)(0.9972246)-Formation of Platelet plug(R)(0.998128)-Neuroactive ligand-receptor interaction(K)(0.9986064)-Proteogylcan syndecan-mediated signaling events(N)(0.9954988)-Regulation of IGF Activity by IGFBP(R)(0.9940818)-Signaling by PDGF(R)(0.9971028)-amb2 Integrin signaling(N)(0.996094)-fibrinolysis pathway(B)(0.932221)-p75(NTR)-mediated signaling(N)(0.9966342) 65 GTF2E2 8p12 0 2 3 33 338 474 254 0.2341 0 0.377889447236181 Basal transcription factors(K)(0.9971404)-Formation and Maturation of mRNA Transcript(R)(0.9976136)-HIV Life Cycle(R)(0.9976872)-Transcription(R)(0.9991612) 66 CD40LG 23q26.3 0 1 3 5 153 469 1409 0.2341 0 0.162814070351759 Asthma(K)(0.9902578)-Autoimmune thyroid disease(K)(0.9850066)-BMP receptor signaling(N)(0.9918134)-Cell adhesion molecules (CAMs)(K)(0.9978986)-Cytokine-cytokine receptor interaction(K)(0.998632)-Endothelins(N)(0.9952746)-Glypican pathway(N)(0.9989418)-Graft-versus-host disease(K)(0.9793104)-IFN-gamma pathway(N)(0.9925178)-IL1-mediated signaling events(N)(0.9877044)-Malaria(K)(0.9957888)-Plasma membrane estrogen receptor signaling(N)(0.9982924)-Primary immunodeficiency(K)(0.9951154)-Systemic lupus erythematosus(K)(0.9989286)-T cell receptor signaling pathway(K)(0.9942284)-TCR signaling in naive CD4+ T cells(N)(0.9943718)-TNF receptor signaling pathway(N)(0.9954942)-TRAIL signaling pathway(N)(0.972611)-Viral myocarditis(K)(0.9984382) 67 RBX1 22q13.2 0 0 0 4 294 464 1053 0.2341 0 0.299497487437186 Cell cycle(K)(0.9958118)-Circadian rhythm - mammal(K)(0.9951918)-Host Interactions of HIV factors(R)(0.9987652)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9928228)-Nucleotide excision repair(K)(0.9969542)-Oocyte meiosis(K)(0.998504)-Pathways in cancer(K)(0.998765)-Protein processing in endoplasmic reticulum(K)(0.9992564)-Renal cell carcinoma(K)(0.9959172)-TGF-beta signaling pathway(K)(0.997162)-Ubiquitin mediated proteolysis(K)(0.9990714)-Wnt signaling pathway(K)(0.997601) 68 CAMK2A 5q33.1 0 0 1 0 101 454 1686 0.2341 0 0.10251256281407 Calcium signaling pathway(K)(0.9980234)-EGFR1(C)(0.9984892)-ErbB signaling pathway(K)(0.9930838)-Gastric acid secretion(K)(0.995423)-Glioma(K)(0.9750472)-Glypican pathway(N)(0.9948666)-GnRH signaling pathway(K)(0.9938432)-IFN-gamma pathway(N)(0.9976176)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9975028)-Long-term potentiation(K)(0.9792922)-Melanogenesis(K)(0.991265)-Neurotrophin signaling pathway(K)(0.994323)-Olfactory transduction(K)(0.9992858)-Oocyte meiosis(K)(0.996457)-Proteogylcan syndecan-mediated signaling events(N)(0.9984952)-TGFBR(C)(0.9980338)-Wnt signaling pathway(K)(0.9981624)-Wnt(C)(0.9959988)-p75(NTR)-mediated signaling(N)(0.9981834)-regulation of pgc-1a(B)(0.9879306)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9913326) 69 PSMD7 16q22.3 0 0 0 11 525 452 501 0.2341 0 0.538693467336683 APC/C-mediated degradation of cell cycle proteins(R)(0.9884946)-Apoptosis(R)(0.9986116)-Cell Cycle Checkpoints(R)(0.9993268)-G1/S Transition(R)(0.9914348)-Host Interactions of HIV factors(R)(0.996189)-Metabolism of amino acids(R)(0.9974072)-Proteasome(K)(0.9909752)-S Phase(R)(0.9938116)-Signaling by Wnt(R)(0.9950754)-TNF alpha/NF-kB(C)(0.9984756) 70 ATP6V1E1 22q11.21 0 0 2 4 288 447 1330 0.2341 0 0.295477386934673 Collecting duct acid secretion(K)(0.9975832)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9980526)-Metabolic pathways(K)(0.9985596)-Oxidative phosphorylation(K)(0.9969884)-Phagosome(K)(0.9983164)-Vibrio cholerae infection(K)(0.9970842) 71 RHOA 3p21.31 0 0 0 0 203 426 2226 0.2397 0 0.204020100502513 Adherens junction(K)(0.9881958)-Alpha6Beta4Integrin(C)(0.9880208)-Angiogenesis(P)(0.9765236)-Axon guidance(K)(0.998472)-Chemokine signaling pathway(K)(0.9974828)-Endocytosis(K)(0.998929)-Focal adhesion(K)(0.9807032)-Glypican pathway(N)(0.9957948)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9976888)-IL2-mediated signaling events(N)(0.9844706)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.988688)-Integrin signalling pathway(P)(0.9973838)-Integrins in angiogenesis(N)(0.9849462)-LPA receptor mediated events(N)(0.9784202)-Leukocyte transendothelial migration(K)(0.9921038)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9906018)-Nectin adhesion pathway(N)(0.9704816)-Neurotrophin signaling pathway(K)(0.9902494)-Pancreatic secretion(K)(0.9967234)-Pathogenic Escherichia coli infection(K)(0.9909842)-Pathways in cancer(K)(0.9994682)-Plasma membrane estrogen receptor signaling(N)(0.976714)-Proteogylcan syndecan-mediated signaling events(N)(0.996779)-Regulation of actin cytoskeleton(K)(0.9929784)-Signaling by Aurora kinases(N)(0.9662668)-Signaling by Rho GTPases(R)(0.9991766)-Signaling events mediated by PRL(N)(0.9817824)-Signaling events mediated by PTP1B(N)(0.992824)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9506636)-Signaling events regulated by Ret tyrosine kinase(N)(0.9855352)-Signalling by NGF(R)(0.99559)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9791896)-T cell receptor signaling pathway(K)(0.9903994)-TGF-beta signaling pathway(K)(0.99816)-TRAIL signaling pathway(N)(0.990416)-Thromboxane A2 receptor signaling(N)(0.9784502)-Tight junction(K)(0.998183)-Vascular smooth muscle contraction(K)(0.9990614)-Wnt signaling pathway(K)(0.998109)-Wnt(C)(0.9964284)-amb2 Integrin signaling(N)(0.9922224)-integrin signaling pathway(B)(0.9461842)-p75(NTR)-mediated signaling(N)(0.9959628)-protein kinase a at the centrosome(B)(0.9253888)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.834681)-thrombin signaling and protease-activated receptors(B)(0.9743842)-trefoil factors initiate mucosal healing(B)(0.9690154) 72 NUP43 6q25.1 0 0 4 4 230 426 512 0.2397 0 0.239195979899497 HIV Life Cycle(R)(0.998153)-Host Interactions of HIV factors(R)(0.9991508)-Influenza Life Cycle(R)(0.998872)-M Phase(R)(0.996604)-Metabolism of carbohydrates(R)(0.9972018)-Metabolism of non-coding RNA(R)(0.9888546)-Transport of Mature Transcript to Cytoplasm(R)(0.9928918) 73 TRA@ NA 0 1 3 5 210 414 91 0.2453 1 0.220100502512563 T cell activation(P)(0.9990272) 74 IFNA1 9p21.3 0 0 3 12 198 394 629 0.2548 0 0.214070351758794 Autoimmune thyroid disease(K)(0.9853642)-Cytokine-cytokine receptor interaction(K)(0.9978662)-Cytosolic DNA-sensing pathway(K)(0.9977356)-Jak-STAT signaling pathway(K)(0.9990106)-Natural killer cell mediated cytotoxicity(K)(0.9988574)-RIG-I-like receptor signaling pathway(K)(0.9978898)-Regulation of autophagy(K)(0.994848)-TCR signaling in naive CD8+ T cells(N)(0.9979508)-Toll-like receptor signaling pathway(K)(0.9952794)-double stranded rna induced gene expression(B)(0.9894226)-signal transduction through il1r(B)(0.994471) 75 STT3A 11q24.2 0 0 0 11 368 387 1310 0.2551 0 0.380904522613065 Insulin Synthesis and Secretion(R)(0.9981082)-Metabolic pathways(K)(0.9985542)-N-Glycan biosynthesis(K)(0.9946006)-Protein processing in endoplasmic reticulum(K)(0.9986788) 76 HDAC2 6q22.1 0 1 3 3 223 363 1507 0.2677 0 0.231155778894472 Cell cycle(K)(0.9945022)-Chronic myeloid leukemia(K)(0.9880538)-Glypican pathway(N)(0.9983232)-Huntington's disease(K)(0.9979584)-IFN-gamma pathway(N)(0.9976592)-NOTCH(C)(0.9972236)-Notch signaling pathway(K)(0.9952036)-Pathways in cancer(K)(0.9986112)-Regulation of Telomerase(N)(0.9984438)-Signaling events mediated by HDAC Class I(N)(0.996062)-Signaling events mediated by the Hedgehog family(N)(0.9970114)-Signalling by NGF(R)(0.9984552)-TNF alpha/NF-kB(C)(0.9983892)-Wnt signaling pathway(P)(0.9989314)-mets affect on macrophage differentiation(B)(0.9925334)-role of mef2d in t-cell apoptosis(B)(0.9764644) 77 FBXL3 13q22.3 0 0 1 5 265 349 223 0.2677 0 0.272361809045226 Circadian rhythm - mammal(K)(0.998356)-Metabolism of proteins(R)(0.9988936) 78 MMP1 11q22.2 0 1 1 12 329 348 690 0.2677 0 0.344723618090452 Alzheimer disease-presenilin pathway(P)(0.9985942)-Bladder cancer(K)(0.9965242)-Cell surface interactions at the vascular wall(R)(0.9983858)-Endothelins(N)(0.9974106)-PPAR signaling pathway(K)(0.9971782)-Pathways in cancer(K)(0.998012)-Plasminogen activating cascade(P)(0.9906764)-Regulation of IGF Activity by IGFBP(R)(0.9932608) 79 CLTC 17q23.1 0 16 38 0 92 341 1324 0.2677 1 0.146733668341709 Bacterial invasion of epithelial cells(K)(0.997779)-Endocytosis(K)(0.9987084)-Gap junction trafficking and regulation(R)(0.989072)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9985854)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9951874)-Huntington's disease(K)(0.9972108)-Influenza Life Cycle(R)(0.9980546)-KitReceptor(C)(0.9975274)-Lysosome(K)(0.9971682)-Membrane Trafficking(R)(0.9966074)-Plasma membrane estrogen receptor signaling(N)(0.997033)-Proteogylcan syndecan-mediated signaling events(N)(0.9987102)-Signaling by EGFR(R)(0.9849506)-Signalling by NGF(R)(0.9983382) 80 ABCD4 14q24.3 0 0 0 1 190 339 118 0.2677 0 0.191959798994975 ABC transporters(K)(0.9988674)-Peroxisome(K)(0.9988912) 81 LCAT 16q22.1 0 0 1 10 454 324 180 0.2677 0 0.467336683417085 Glycerophospholipid metabolism(K)(0.998037)-Metabolism of lipids and lipoproteins(R)(0.9983222) 82 MAOA 23p11.3 0 0 1 5 150 322 1213 0.2677 0 0.15678391959799 Biological oxidations(R)(0.9978632)-Drug metabolism - cytochrome P450(K)(0.9987658)-Glycine, serine and threonine metabolism(K)(0.9976332)-Histidine metabolism(K)(0.9970132)-Metabolic pathways(K)(0.9986328)-Synaptic Transmission(R)(0.9989288)-Tryptophan metabolism(K)(0.9889862) 83 ADORA2B 17p12 0 0 1 10 423 321 549 0.2677 0 0.436180904522613 Calcium signaling pathway(K)(0.9974176)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9977206)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9947984)-Neuroactive ligand-receptor interaction(K)(0.9986588)-Vascular smooth muscle contraction(K)(0.9979934) 84 ALDH3A2 17p11.2 0 0 5 4 332 313 1184 0.2677 0 0.342713567839196 Fatty acid metabolism(K)(0.9959646)-Glycerolipid metabolism(K)(0.9836024)-Histidine metabolism(K)(0.9975676)-Lysine degradation(K)(0.9987714)-Metabolic pathways(K)(0.9980832)-Pyruvate metabolism(K)(0.9983164)-Tryptophan metabolism(K)(0.9956102) 85 DHX38 16q22.3 0 0 0 10 506 313 306 0.2677 0 0.518592964824121 Formation and Maturation of mRNA Transcript(R)(0.9922894)-Spliceosome(K)(0.9982908)-Transcription(R)(0.9977518)-Transport of Mature Transcript to Cytoplasm(R)(0.998016) 86 PANK4 1p36.32 0 0 0 2 210 312 1122 0.2677 0 0.213065326633166 Metabolic pathways(K)(0.9990052)-Pantothenate and CoA biosynthesis(K)(0.9523658) 87 MEF2C 5q14.3 0 0 0 1 158 310 1170 0.2677 0 0.159798994974874 BMP receptor signaling(N)(0.9953948)-Glypican pathway(N)(0.9977568)-IFN-gamma pathway(N)(0.9968256)-IL1-mediated signaling events(N)(0.9939524)-MAPK signaling pathway(K)(0.9973274)-NOTCH(C)(0.9976836)-Oxidative stress response(P)(0.9860518)-Plasma membrane estrogen receptor signaling(N)(0.9963546)-Regulation of retinoblastoma protein(N)(0.9972608)-Signaling events mediated by HDAC Class I(N)(0.9970602)-Signalling by NGF(R)(0.9980366)-TGFBR(C)(0.9968968)-TNF receptor signaling pathway(N)(0.9987454)-alk in cardiac myocytes(B)(0.9911028)-angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling(B)(0.9294686)-carm1 and regulation of the estrogen receptor(B)(0.9920874)-nfat and hypertrophy of the heart (B)(0.9943086)-p38 mapk signaling pathway(B)(0.9923016)-p75(NTR)-mediated signaling(N)(0.9967138)-regulation of pgc-1a(B)(0.9914506) 88 GNAO1 16q13 0 0 2 9 473 310 935 0.2677 0 0.48643216080402 Androgen-mediated signaling(N)(0.9687722)-Chagas disease(K)(0.9971458)-Endothelins(N)(0.9954714)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9935218)-LPA receptor mediated events(N)(0.9948654)-Long-term depression(K)(0.99725)-Melanogenesis(K)(0.9935462)-Opioid Signalling(R)(0.9968916)-Plasma membrane estrogen receptor signaling(N)(0.9930774)-Receptor-ligand complexes bind G proteins(R)(0.9954188)-Signaling events mediated by the Hedgehog family(N)(0.997589)-Sphingosine 1-phosphate (S1P) pathway(N)(0.997756) 89 FXYD2 11q23.3 0 0 0 10 343 309 274 0.2677 0 0.354773869346734 Aldosterone-regulated sodium reabsorption(K)(0.9970868)-Cardiac muscle contraction(K)(0.9992392)-Pancreatic secretion(K)(0.9970494)-Proximal tubule bicarbonate reclamation(K)(0.9973694)-Salivary secretion(K)(0.998273)-oxidative stress induced gene expression via nrf2(B)(0.9970374) 90 IL18 11q23.1 0 0 0 13 368 306 509 0.2677 0 0.382914572864322 Cellular roles of Anthrax toxin(N)(0.993462)-Cytokine-cytokine receptor interaction(K)(0.9998254)-Cytosolic DNA-sensing pathway(K)(0.9972918)-IL12-mediated signaling events(N)(0.9983864)-IL23-mediated signaling events(N)(0.9948766)-Interleukin signaling pathway(P)(0.9955678)-Malaria(K)(0.998922)-NOD-like receptor signaling pathway(K)(0.9984564)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.997171) 91 ETS1 11q24.3 0 0 0 11 362 302 974 0.2677 0 0.374874371859297 Angiogenesis(P)(0.9975048)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9935438)-Dorso-ventral axis formation(K)(0.997576)-Glypican pathway(N)(0.9946234)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9968124)-IFN-gamma pathway(N)(0.9982208)-Pathways in cancer(K)(0.998912)-Ras Pathway(P)(0.9934392)-Renal cell carcinoma(K)(0.9925466)-TGFBR(C)(0.9981812)-TRAIL signaling pathway(N)(0.9989846)-keratinocyte differentiation(B)(0.989331)-mets affect on macrophage differentiation(B)(0.9942906) 92 PIK3CA 3q26.32 0 2 8 0 30 299 2397 0.2677 1 0.0402010050251256 Aldosterone-regulated sodium reabsorption(K)(0.9881668)-Alpha6Beta4Integrin(C)(0.9844532)-Amoebiasis(K)(0.9943116)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9835086)-Apoptosis(K)(0.9513812)-B cell receptor signaling pathway(K)(0.9759068)-Cell surface interactions at the vascular wall(R)(0.9961828)-Chemokine signaling pathway(K)(0.998838)-EGF receptor signaling pathway(P)(0.8876184)-EGFR1(C)(0.997763)-Endothelins(N)(0.992047)-ErbB signaling pathway(K)(0.8276936)-FGF signaling pathway(P)(0.971095)-Fc gamma R-mediated phagocytosis(K)(0.9938676)-Fc-epsilon receptor I signaling in mast cells(N)(0.9383526)-Focal adhesion(K)(0.9043642)-Glypican pathway(N)(0.9980924)-Hypoxia response via HIF activation(P)(0.9184976)-IFN-gamma pathway(N)(0.9741254)-IL12-mediated signaling events(N)(0.9921074)-IL6-mediated signaling events(N)(0.9843124)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9606372)-Inositol phosphate metabolism(K)(0.9839024)-Insulin signaling pathway(K)(0.997672)-Integrin signalling pathway(P)(0.9979676)-Jak-STAT signaling pathway(K)(0.9992066)-LPA receptor mediated events(N)(0.9899086)-Leukocyte transendothelial migration(K)(0.9953494)-Natural killer cell mediated cytotoxicity(K)(0.9878308)-Nectin adhesion pathway(N)(0.988334)-Neurotrophin signaling pathway(K)(0.9610808)-Pathways in cancer(K)(0.9998304)-Phosphatidylinositol signaling system(K)(0.9890352)-Progesterone-mediated oocyte maturation(K)(0.9929086)-Prostate cancer(K)(0.9857042)-Proteogylcan syndecan-mediated signaling events(N)(0.9985448)-Reelin signaling pathway(N)(0.9876728)-Regulation of actin cytoskeleton(K)(0.9987708)-Signaling by Aurora kinases(N)(0.9844078)-Signaling by EGFR(R)(0.917387)-Signaling events mediated by PTP1B(N)(0.8429672)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9360024)-Signaling events mediated by the Hedgehog family(N)(0.9947098)-Signaling events regulated by Ret tyrosine kinase(N)(0.9679358)-Signalling by NGF(R)(0.9969806)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9846832)-TCR signaling in naive CD4+ T cells(N)(0.9955034)-TNF receptor signaling pathway(N)(0.9786258)-Toll-like receptor signaling pathway(K)(0.997437)-Type II diabetes mellitus(K)(0.9916646)-actions of nitric oxide in the heart(B)(0.9936856)-b cell survival pathway(B)(0.9691248)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.94738)-ctcf: first multivalent nuclear factor(B)(0.9808602)-il-2 receptor beta chain in t cell activation(B)(0.9837858)-mTOR signaling pathway(K)(0.9897602)-nfat and hypertrophy of the heart (B)(0.9924602)-p53 pathway(P)(0.988964)-p75(NTR)-mediated signaling(N)(0.9980766)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.990232)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9875122)-the igf-1 receptor and longevity(B)(0.9766706)-thrombin signaling and protease-activated receptors(B)(0.9871802)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9736232) 93 SHC2 19p13.3 0 0 2 3 210 292 881 0.2677 0 0.21608040201005 Angiogenesis(P)(0.9953948)-Bacterial invasion of epithelial cells(K)(0.9979644)-Chemokine signaling pathway(K)(0.9984258)-Chronic myeloid leukemia(K)(0.9972406)-ErbB signaling pathway(K)(0.9874892)-Focal adhesion(K)(0.998119)-Insulin signaling pathway(K)(0.9995086)-Natural killer cell mediated cytotoxicity(K)(0.9982008)-Neurotrophin signaling pathway(K)(0.9983978)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9962388)-Signalling by NGF(R)(0.9967118)-VEGF signaling pathway(K)(0.9960006)-p75(NTR)-mediated signaling(N)(0.9983016) 94 FUK 16q22.1 0 0 1 8 474 290 1134 0.2677 0 0.485427135678392 Amino sugar and nucleotide sugar metabolism(K)(0.9982894)-Fructose and mannose metabolism(K)(0.998127)-Metabolic pathways(K)(0.9993896) 95 NFATC3 16q22.1 0 0 0 11 483 290 1280 0.2677 0 0.496482412060302 Axon guidance(K)(0.9985394)-B cell receptor signaling pathway(K)(0.9916234)-BMP receptor signaling(N)(0.9980446)-Endothelins(N)(0.9937374)-Glypican pathway(N)(0.9964388)-IFN-gamma pathway(N)(0.9993318)-IL1-mediated signaling events(N)(0.9943082)-Natural killer cell mediated cytotoxicity(K)(0.9974322)-Plasma membrane estrogen receptor signaling(N)(0.996247)-T cell receptor signaling pathway(K)(0.9777462)-TCR signaling in naive CD4+ T cells(N)(0.9925944)-TNF receptor signaling pathway(N)(0.9952456)-TRAIL signaling pathway(N)(0.973142)-VEGF signaling pathway(K)(0.994127)-Wnt signaling pathway(K)(0.9973032)-Wnt signaling pathway(P)(0.997835) 96 BCL2 18q21.33 0 0 2 1 203 285 1450 0.2677 1 0.207035175879397 Amyotrophic lateral sclerosis (ALS)(K)(0.9925314)-Apoptosis(K)(0.9958436)-Apoptosis(R)(0.9965804)-BMP receptor signaling(N)(0.996412)-Endothelins(N)(0.9972628)-FAS signaling pathway (CD95)(N)(0.9921594)-Focal adhesion(K)(0.9968488)-Glypican pathway(N)(0.9968546)-IFN-gamma pathway(N)(0.9969128)-IL1-mediated signaling events(N)(0.9946822)-IL2-mediated signaling events(N)(0.9954434)-Neurotrophin signaling pathway(K)(0.9983722)-Oxidative stress response(P)(0.9972648)-Pathways in cancer(K)(0.9985016)-Plasma membrane estrogen receptor signaling(N)(0.9980728)-Prostate cancer(K)(0.9924754)-Protein processing in endoplasmic reticulum(K)(0.998226)-Retinoic acid receptors-mediated signaling(N)(0.9974046)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.993683)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9978318)-TNF receptor signaling pathway(N)(0.9960634)-il-2 receptor beta chain in t cell activation(B)(0.9671386)-keratinocyte differentiation(B)(0.9827454)-prion pathway(B)(0.9872578)-telomeres telomerase cellular aging and immortality(B)(0.9921542)-transcription regulation by methyltransferase of carm1(B)(0.950789) 97 FCGR2B 1q23.3 0 0 10 0 49 281 979 0.2677 1 0.0592964824120603 B cell receptor signaling pathway(K)(0.9948518)-Fc gamma R-mediated phagocytosis(K)(0.9972236)-Fc-epsilon receptor I signaling in mast cells(N)(0.9958364)-Glypican pathway(N)(0.9977822)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.996799)-Phagosome(K)(0.9986094)-Systemic lupus erythematosus(K)(0.9985816)-TRAIL signaling pathway(N)(0.9970814) 98 CYLD 16q12.1 0 0 1 7 463 279 880 0.2677 1 0.473366834170854 Glypican pathway(N)(0.9964098)-IL1-mediated signaling events(N)(0.9972782)-IL12-mediated signaling events(N)(0.998104)-IL2-mediated signaling events(N)(0.993389)-IL23-mediated signaling events(N)(0.9880498)-LPA receptor mediated events(N)(0.9950542)-RIG-I-like receptor signaling pathway(K)(0.9981676)-Signaling by Aurora kinases(N)(0.9777068)-Signaling events regulated by Ret tyrosine kinase(N)(0.9938528)-TCR signaling in naive CD4+ T cells(N)(0.995795)-TNF receptor signaling pathway(N)(0.9975772)-TRAIL signaling pathway(N)(0.9905594)-p75(NTR)-mediated signaling(N)(0.9984066) 99 CYP2A6 19q13.2 0 0 2 1 67 275 1168 0.2677 0 0.0703517587939698 Biological oxidations(R)(0.998276)-Drug metabolism - cytochrome P450(K)(0.9967936)-Drug metabolism - other enzymes(K)(0.9749886)-Metabolic pathways(K)(0.997819)-Retinol metabolism(K)(0.9967774) 100 C1QA 1p36.12 0 0 0 2 231 268 371 0.2677 0 0.234170854271357 Chagas disease(K)(0.9988576)-Complement and coagulation cascades(K)(0.9984906)-Innate Immunity Signaling(R)(0.9936312)-Prion diseases(K)(0.9959598)-Systemic lupus erythematosus(K)(0.9981564) 101 OR3A3 17p13.3 0 0 0 7 426 266 413 0.2677 0 0.435175879396985 Olfactory transduction(K)(0.9996266) 102 GGT6 17p13.2 0 0 0 5 404 261 1162 0.2677 0 0.41105527638191 Arachidonic acid metabolism(K)(0.9829276)-Glutathione metabolism(K)(0.9985464)-Metabolic pathways(K)(0.9993192)-Selenoamino acid metabolism(K)(0.9972422) 103 CLTCL1 22q11.21 0 0 3 1 264 256 720 0.2677 1 0.269346733668342 Bacterial invasion of epithelial cells(K)(0.9980952)-Endocytosis(K)(0.9988976)-Gap junction trafficking and regulation(R)(0.9952216)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9990682)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9970018)-Huntington's disease(K)(0.9976862)-Lysosome(K)(0.9966532) 104 MLYCD 16q23.3 0 0 1 8 498 251 1167 0.2677 0 0.509547738693467 Metabolic pathways(K)(0.9989724)-Peroxisome(K)(0.999235) 105 PLCB2 15q15.1 0 0 1 3 182 250 2547 0.2677 0 0.186934673366834 Alpha-synuclein signaling(N)(0.984635)-Alzheimer's disease(K)(0.9958316)-Amoebiasis(K)(0.9985174)-Calcium signaling pathway(K)(0.9988508)-Chagas disease(K)(0.9961066)-Chemokine signaling pathway(K)(0.9979636)-Endothelin signaling pathway(P)(0.9841158)-Endothelins(N)(0.9910152)-Gap junction(K)(0.9954236)-Gastric acid secretion(K)(0.992733)-GnRH signaling pathway(K)(0.9812934)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9972976)-Huntington's disease(K)(0.9974312)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.995563)-Inositol phosphate metabolism(K)(0.9735732)-Long-term depression(K)(0.986078)-Long-term potentiation(K)(0.9862998)-Melanogenesis(K)(0.967889)-Metabolic pathways(K)(0.9995004)-Pancreatic secretion(K)(0.996049)-Plasma membrane estrogen receptor signaling(N)(0.996148)-Salivary secretion(K)(0.9974356)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9973308)-Taste transduction(K)(0.995677)-Thromboxane A2 receptor signaling(N)(0.9833048)-Vascular smooth muscle contraction(K)(0.996174)-Wnt signaling pathway(K)(0.9966196)-Wnt signaling pathway(P)(0.9984746) 106 MAPK8 10q11.22 0 0 3 1 96 247 2330 0.2677 0 0.100502512562814 Adipocytokine signaling pathway(K)(0.9971086)-Alzheimer disease-amyloid secretase pathway(P)(0.9909616)-Angiogenesis(P)(0.9850376)-Angiopoietin receptor Tie2-mediated signaling(N)(0.957965)-Apoptosis(R)(0.9957898)-BMP receptor signaling(N)(0.986483)-Chagas disease(K)(0.997541)-EGF receptor signaling pathway(P)(0.9593754)-EGFR1(C)(0.9940742)-Endothelins(N)(0.9899646)-EphrinB-EPHB pathway(N)(0.931963)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9922916)-ErbB signaling pathway(K)(0.943221)-FAS signaling pathway (CD95)(N)(0.9128856)-FAS signaling pathway(P)(0.97953)-Fc-epsilon receptor I signaling in mast cells(N)(0.9802584)-Focal adhesion(K)(0.9991976)-FoxO family signaling(N)(0.9794844)-Glypican pathway(N)(0.9858832)-GnRH signaling pathway(K)(0.9810582)-IFN-gamma pathway(N)(0.9275546)-IL1-mediated signaling events(N)(0.9644278)-IL12-mediated signaling events(N)(0.9950582)-IL2-mediated signaling events(N)(0.9796968)-Insulin signaling pathway(K)(0.998394)-Integrin signalling pathway(P)(0.994423)-Integrins in angiogenesis(N)(0.988985)-MAPK signaling pathway(K)(0.9975546)-NOD-like receptor signaling pathway(K)(0.9914462)-Neurotrophin signaling pathway(K)(0.9678476)-Pathways in cancer(K)(0.99945)-Plasma membrane estrogen receptor signaling(N)(0.9530324)-Progesterone-mediated oocyte maturation(K)(0.994602)-Protein processing in endoplasmic reticulum(K)(0.9989914)-Proteogylcan syndecan-mediated signaling events(N)(0.9970798)-RIG-I-like receptor signaling pathway(K)(0.9975066)-Reelin signaling pathway(N)(0.9730144)-Retinoic acid receptors-mediated signaling(N)(0.9871252)-Shigellosis(K)(0.9875926)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9789724)-Signaling events regulated by Ret tyrosine kinase(N)(0.9798718)-Signalling by NGF(R)(0.9968208)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9934468)-TCR signaling in naive CD4+ T cells(N)(0.9767228)-TGF-beta signaling pathway(P)(0.9952974)-TGFBR(C)(0.9963738)-TNF receptor signaling pathway(N)(0.9719964)-TRAIL signaling pathway(N)(0.9869232)-Toll-like receptor signaling pathway(K)(0.9941168)-Type II diabetes mellitus(K)(0.9708932)-Wnt signaling pathway(K)(0.9972252)-Wnt(C)(0.9958586)-agrin in postsynaptic differentiation(B)(0.9860306)-how progesterone initiates the oocyte maturation(B)(0.9465048)-il-10 anti-inflammatory signaling pathway(B)(0.9360068)-lectin induced complement pathway(B)(0.9854134)-p75(NTR)-mediated signaling(N)(0.9982648) 107 B3GAT1 11q25 0 1 0 13 334 246 1139 0.2677 0 0.349748743718593 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9967792)-Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9980372)-Metabolic pathways(K)(0.9986938) 108 MRE11A 11q21 0 0 6 10 306 246 187 0.2677 0 0.323618090452261 BARD1 signaling events(N)(0.9979654)-DNA Repair(R)(0.9983062)-Homologous recombination(K)(0.9966974)-Non-homologous end-joining(K)(0.995323)-Regulation of Telomerase(N)(0.9979014)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.8585218) 109 ENPP1 6q23.2 0 1 6 2 194 239 1216 0.2677 0 0.204020100502513 Metabolic pathways(K)(0.999746)-Metabolism of vitamins and cofactors(R)(0.9947086)-Nicotinate and nicotinamide metabolism(K)(0.8959026)-Purine metabolism(K)(0.9968954)-Riboflavin metabolism(K)(0.9940724)-Starch and sucrose metabolism(K)(0.997581)-regulators of bone mineralization(B)(0.99597) 110 CNOT7 8p22 0 1 4 28 347 239 59 0.2677 0 0.381909547738693 RNA degradation(K)(0.9992726) 111 PARK2 6q26 0 0 0 12 261 237 468 0.2677 0 0.274371859296482 Alpha-synuclein signaling(N)(0.995871)-Parkinson disease(P)(0.997425)-Parkinson's disease(K)(0.9956254)-Protein processing in endoplasmic reticulum(K)(0.9983928)-Ubiquitin mediated proteolysis(K)(0.997782) 112 GRB7 17q12 0 81 34 0 137 235 500 0.2677 0 0.253266331658291 Angiogenesis(P)(0.9973226)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9899604)-Cell surface interactions at the vascular wall(R)(0.9971466)-EGFR1(C)(0.9985672)-EphrinB-EPHB pathway(N)(0.979581)-KitReceptor(C)(0.9948198)-Nectin adhesion pathway(N)(0.9957524)-Signaling by PDGF(R)(0.9967396)-Signaling events regulated by Ret tyrosine kinase(N)(0.9983766)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9968428) 113 HARS2 NA 0 0 2 0 150 235 44 0.2677 0 0.152763819095477 Aminoacyl-tRNA biosynthesis(K)(0.9978986)-tRNA Aminoacylation(R)(0.9933034) 114 PPAP2C 19p13.3 0 0 0 2 220 232 1228 0.2677 0 0.223115577889447 Ether lipid metabolism(K)(0.9786428)-Fc gamma R-mediated phagocytosis(K)(0.9989612)-Glycerophospholipid metabolism(K)(0.9975122)-Metabolic pathways(K)(0.9996956)-Sphingolipid metabolism(K)(0.9952502) 115 PDX1 13q12.2 0 0 4 3 247 231 182 0.2677 0 0.255276381909548 FOXA transcription factor networks(N)(0.9849034)-Insulin Synthesis and Secretion(R)(0.9982222)-Maturity onset diabetes of the young(K)(0.989296)-Regulation of beta-cell development(R)(0.9957958)-Type II diabetes mellitus(K)(0.9978722) 116 HTR2C 23q23 0 0 1 9 186 230 650 0.2677 0 0.196984924623116 Calcium signaling pathway(K)(0.9976792)-Class A/1 (Rhodopsin-like receptors)(R)(0.9972582)-Gap junction(K)(0.999168)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9967958)-Neuroactive ligand-receptor interaction(K)(0.9984722)-Receptor-ligand complexes bind G proteins(R)(0.9952308)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.995052)-chrebp regulation by carbohydrates and camp(B)(0.9947672)-ion channels and their functional role in vascular endothelium(B)(0.9955018)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9760862)-ß-arrestins in gpcr desensitization(B)(0.987055) 117 ATP6V1B2 8p21.3 0 1 3 28 363 230 1330 0.2677 0 0.396984924623116 Collecting duct acid secretion(K)(0.9908996)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9978506)-Metabolic pathways(K)(0.9990752)-Oxidative phosphorylation(K)(0.9963458)-Phagosome(K)(0.9986244)-Vibrio cholerae infection(K)(0.9976764) 118 JAM3 11q25 0 1 0 13 345 226 475 0.2695 0 0.360804020100502 Cell adhesion molecules (CAMs)(K)(0.9990136)-Cell surface interactions at the vascular wall(R)(0.9972568)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9987348)-Integrin cell surface interactions(R)(0.997537)-Leukocyte transendothelial migration(K)(0.9965148)-Tight junction(K)(0.9995186)-amb2 Integrin signaling(N)(0.9964242) 119 CSNK1E 22q13.1 0 1 2 2 279 221 569 0.273 0 0.285427135678392 Circadian rhythm - mammal(K)(0.9940252)-Circadian rhythm pathway(N)(0.971338)-FoxO family signaling(N)(0.9917448)-G2/M Transition(R)(0.9992932)-Hedgehog signaling pathway(K)(0.996811)-Signaling events mediated by the Hedgehog family(N)(0.9980612)-Wnt signaling pathway(K)(0.997994)-Wnt signaling pathway(P)(0.9983878)-Wnt(C)(0.9954434) 120 SMAD2 18q21.1 0 0 0 5 218 216 1261 0.2761 0 0.224120603015075 Adherens junction(K)(0.9960272)-Alpha6Beta4Integrin(C)(0.9936852)-Cell cycle(K)(0.998229)-Chagas disease(K)(0.9978614)-EGFR1(C)(0.9986602)-Endocytosis(K)(0.999261)-Glypican pathway(N)(0.9950964)-IFN-gamma pathway(N)(0.9944916)-Pathways in cancer(K)(0.99759)-TGF-beta signaling pathway(K)(0.997329)-TGF-beta signaling pathway(P)(0.995339)-TGFBR(C)(0.996855)-Wnt signaling pathway(K)(0.9970428)-tgf beta signaling pathway(B)(0.9919882) 121 PAPSS2 10q23.2 0 0 1 7 141 211 1199 0.2777 0 0.149748743718593 Metabolic pathways(K)(0.9993196)-Purine metabolism(K)(0.9994136)-Selenoamino acid metabolism(K)(0.9962898)-Sulfur metabolism(K)(0.997582) 122 SIAH1 16q12.1 0 1 1 11 426 208 576 0.2777 0 0.441206030150754 Ubiquitin mediated proteolysis(K)(0.997796)-Wnt signaling pathway(K)(0.9983626)-Wnt signaling pathway(P)(0.999138)-p53 pathway feedback loops 2(P)(0.9989202)-p53 pathway(P)(0.9909486)-p53 signaling pathway(K)(0.9991126) 123 ATP6V0A4 7q34 0 0 4 5 108 208 1416 0.2777 0 0.117587939698492 Collecting duct acid secretion(K)(0.9932648)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9970564)-Lysosome(K)(0.9997896)-Metabolic pathways(K)(0.9985358)-Oxidative phosphorylation(K)(0.9961116)-Phagosome(K)(0.9987132)-Vibrio cholerae infection(K)(0.9958874) 124 RPS23 5q14.2 0 0 1 1 145 207 313 0.2777 0 0.147738693467337 Influenza Life Cycle(R)(0.9977584)-Metabolism of proteins(R)(0.997794) 125 PPYR1 10q11.22 0 0 0 3 162 199 371 0.2805 0 0.165829145728643 Class A/1 (Rhodopsin-like receptors)(R)(0.9981688)-Neuroactive ligand-receptor interaction(K)(0.9976888)-akap95 role in mitosis and chromosome dynamics(B)(0.9948882)-regulation of eif2(B)(0.99796) 126 CA7 16q22.1 0 0 0 10 506 198 23 0.2805 0 0.518592964824121 Nitrogen metabolism(K)(0.998592) 127 ARHGEF12 11q23.3 0 0 1 13 360 197 512 0.2805 1 0.375879396984925 Axon guidance(K)(0.9963326)-Regulation of actin cytoskeleton(K)(0.9992664)-Signaling by Rho GTPases(R)(0.9982936)-Vascular smooth muscle contraction(K)(0.9990436) 128 NUP210 3p25.1 0 0 5 0 100 196 520 0.2805 0 0.105527638190955 HIV Life Cycle(R)(0.9955134)-Host Interactions of HIV factors(R)(0.9969154)-Influenza Life Cycle(R)(0.996445)-Metabolism of carbohydrates(R)(0.9977752)-Metabolism of non-coding RNA(R)(0.9951904)-Signaling events mediated by HDAC Class I(N)(0.998217)-Transport of Mature Transcript to Cytoplasm(R)(0.9935856)-mechanism of protein import into the nucleus(B)(0.8693816) 129 MAML2 11q21 0 0 2 10 312 194 70 0.2805 1 0.325628140703518 Generic Transcription Pathway(R)(0.9982204)-Notch signaling pathway(K)(0.9994222) 130 CENPN 16q23.2 0 0 0 10 511 190 96 0.2805 0 0.523618090452261 M Phase(R)(0.9994238) 131 GOT2 16q21 0 0 0 11 495 188 1252 0.2805 0 0.508542713567839 Alanine, aspartate and glutamate metabolism(K)(0.99638)-Metabolic pathways(K)(0.99878)-Metabolism of amino acids(R)(0.9992962)-Metabolism of carbohydrates(R)(0.9994598)-Tyrosine metabolism(K)(0.9787098) 132 CCND1 11q13.2 0 23 77 0 46 188 1735 0.2805 1 0.146733668341709 Androgen-mediated signaling(N)(0.9712528)-AndrogenReceptor(C)(0.993487)-BMP receptor signaling(N)(0.9958172)-Cell cycle(K)(0.9941456)-FOXM1 transcription factor network(N)(0.9941088)-Focal adhesion(K)(0.9986392)-Glioma(K)(0.9832352)-Glypican pathway(N)(0.9972346)-IFN-gamma pathway(N)(0.995068)-Jak-STAT signaling pathway(K)(0.9994022)-Nectin adhesion pathway(N)(0.9984614)-Pathways in cancer(K)(0.9971494)-Presenilin action in Notch and Wnt signaling(N)(0.9891508)-Prostate cancer(K)(0.9902736)-Regulation of Telomerase(N)(0.9948238)-Regulation of retinoblastoma protein(N)(0.9945016)-S Phase(R)(0.9910546)-TGFBR(C)(0.997911)-Viral myocarditis(K)(0.994695)-Wnt signaling pathway(K)(0.995848)-Wnt signaling pathway(P)(0.998833)-il-2 receptor beta chain in t cell activation(B)(0.9463362)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9892228)-p53 signaling pathway(K)(0.9960758)-p75(NTR)-mediated signaling(N)(0.9986086) 133 UGT2A1 4q13.3 0 0 4 1 87 188 1192 0.2805 0 0.0924623115577889 Drug metabolism - cytochrome P450(K)(0.9953366)-Drug metabolism - other enzymes(K)(0.9889044)-Metabolic pathways(K)(0.998889)-Metabolism of xenobiotics by cytochrome P450(K)(0.9948922)-Porphyrin and chlorophyll metabolism(K)(0.9923552)-Retinol metabolism(K)(0.9969914)-Starch and sucrose metabolism(K)(0.9975896)-Steroid hormone biosynthesis(K)(0.9968266) 134 MTHFD1L 6q25.1 0 1 3 4 209 186 1124 0.2805 0 0.218090452261307 Metabolic pathways(K)(0.9970312)-One carbon pool by folate(K)(0.9960202) 135 PANX1 11q21 0 0 3 10 292 184 42 0.2805 0 0.306532663316583 Synaptic Transmission(R)(0.999217) 136 RPS6KB1 17q23.1 0 18 41 0 84 182 1278 0.2805 0 0.143718592964824 Acute myeloid leukemia(K)(0.991977)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9947788)-Endothelins(N)(0.9983516)-ErbB signaling pathway(K)(0.996463)-Fc gamma R-mediated phagocytosis(K)(0.9983074)-Glypican pathway(N)(0.9992044)-IFN-gamma pathway(N)(0.9983112)-IL2-mediated signaling events(N)(0.9924204)-Insulin signaling pathway(K)(0.9978206)-Integrins in angiogenesis(N)(0.9967914)-Plasma membrane estrogen receptor signaling(N)(0.994619)-Proteogylcan syndecan-mediated signaling events(N)(0.9969062)-Regulation of Telomerase(N)(0.9967828)-Retinoic acid receptors-mediated signaling(N)(0.9935808)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9927664)-TGF-beta signaling pathway(K)(0.9983412)-TNF alpha/NF-kB(C)(0.9987644)-TRAIL signaling pathway(N)(0.9946582)-a6b1 and a6b4 Integrin signaling(N)(0.9955148)-ctcf: first multivalent nuclear factor(B)(0.9538546)-il-2 receptor beta chain in t cell activation(B)(0.9906522)-mTOR signaling pathway(K)(0.9959344)-nfat and hypertrophy of the heart (B)(0.9954424)-p53 pathway by glucose deprivation(P)(0.9813426)-phosphoinositides and their downstream targets(B)(0.9900934)-rac1 cell motility signaling pathway(B)(0.994689)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9732296) 137 SNRPD1 18q11.2 0 0 2 2 175 182 502 0.2805 0 0.179899497487437 Formation and Maturation of mRNA Transcript(R)(0.9969608)-Influenza Life Cycle(R)(0.99537)-Metabolism of non-coding RNA(R)(0.9913408)-Spliceosome(K)(0.9982684)-Systemic lupus erythematosus(K)(0.9992516) 138 BMPR2 2q33.1 0 0 2 3 157 180 548 0.2805 0 0.162814070351759 BMP receptor signaling(N)(0.998178)-Cytokine-cytokine receptor interaction(K)(0.9989884)-Signaling by BMP(R)(0.9961956)-TGF-beta signaling pathway(K)(0.9979506)-TGF-beta signaling pathway(P)(0.9981354) 139 CD3E 11q23.3 0 0 1 10 363 179 586 0.2805 0 0.375879396984925 Chagas disease(K)(0.9986244)-Hematopoietic cell lineage(K)(0.9990238)-IL12-mediated signaling events(N)(0.9963404)-IL23-mediated signaling events(N)(0.9964034)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9975728)-Primary immunodeficiency(K)(0.9988252)-T cell receptor signaling pathway(K)(0.9961228)-TCR signaling in naive CD4+ T cells(N)(0.9987298)-TCR signaling(R)(0.9967306)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9796172)-role of mef2d in t-cell apoptosis(B)(0.9949626)-t cell receptor signaling pathway(B)(0.9922038) 140 HEXB 5q13.3 0 0 0 3 146 179 1228 0.2805 0 0.149748743718593 Amino sugar and nucleotide sugar metabolism(K)(0.9976778)-Lysosome(K)(0.9994688)-Metabolic pathways(K)(0.9986138)-Other glycan degradation(K)(0.9967588) 141 BAAT 9q31.1 0 0 0 1 160 175 1185 0.2835 0 0.161809045226131 Biosynthesis of unsaturated fatty acids(K)(0.9985222)-Metabolic pathways(K)(0.9987948)-Peroxisome(K)(0.9988634)-Primary bile acid biosynthesis(K)(0.9973932) 142 PAK2 3q29 0 0 2 0 73 174 1389 0.2835 0 0.0753768844221105 Apoptosis(R)(0.9971056)-Axon guidance(K)(0.996996)-BMP receptor signaling(N)(0.9947662)-ErbB signaling pathway(K)(0.9920668)-FAS signaling pathway (CD95)(N)(0.9897884)-Fc-epsilon receptor I signaling in mast cells(N)(0.99586)-Focal adhesion(K)(0.9964014)-Glypican pathway(N)(0.9966438)-Host Interactions of HIV factors(R)(0.9991206)-IFN-gamma pathway(N)(0.9975314)-IL1-mediated signaling events(N)(0.9946738)-MAPK signaling pathway(K)(0.9979978)-Plasma membrane estrogen receptor signaling(N)(0.9991952)-Regulation of actin cytoskeleton(K)(0.9990244)-Renal cell carcinoma(K)(0.9953466)-T cell receptor signaling pathway(K)(0.994627)-TNF receptor signaling pathway(N)(0.9973404)-agrin in postsynaptic differentiation(B)(0.9894422)-mapkinase signaling pathway(B)(0.9851332) 143 OR2A7 6q23.2 0 1 4 2 188 172 389 0.2847 0 0.195979899497487 Olfactory transduction(K)(0.9965938) 144 MAP3K7 6q15 0 0 0 1 240 170 1587 0.2855 0 0.242211055276382 Adherens junction(K)(0.9977736)-BMP receptor signaling(N)(0.9948236)-EphrinB-EPHB pathway(N)(0.9484038)-FAS signaling pathway (CD95)(N)(0.9659406)-Glypican pathway(N)(0.9970828)-IFN-gamma pathway(N)(0.9951516)-IL1-mediated signaling events(N)(0.9358852)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9974278)-Interleukin signaling pathway(P)(0.9905924)-Leishmaniasis(K)(0.9916652)-MAPK signaling pathway(K)(0.9986464)-NOD-like receptor signaling pathway(K)(0.9974314)-Presenilin action in Notch and Wnt signaling(N)(0.9875338)-Proteogylcan syndecan-mediated signaling events(N)(0.9965748)-RIG-I-like receptor signaling pathway(K)(0.9971282)-T cell receptor signaling pathway(K)(0.9944042)-TCR signaling in naive CD4+ T cells(N)(0.9892974)-TNF receptor signaling pathway(N)(0.9903538)-TRAIL signaling pathway(N)(0.9914726)-Toll-like receptor signaling pathway(K)(0.9952972)-Wnt signaling pathway(K)(0.9980322)-Wnt signaling pathway(P)(0.9993078)-alk in cardiac myocytes(B)(0.9887588)-classical complement pathway(B)(0.9609794)-lectin induced complement pathway(B)(0.9694756)-mapkinase signaling pathway(B)(0.9791152)-signal transduction through il1r(B)(0.9789914)-tgf beta signaling pathway(B)(0.9825372)-thrombin signaling and protease-activated receptors(B)(0.9939018)-toll-like receptor pathway(B)(0.966992) 145 NNMT 11q23.2 0 0 1 11 357 165 1144 0.2915 0 0.370854271356784 Biological oxidations(R)(0.997873)-Metabolic pathways(K)(0.9986674) 146 MAPK9 5q35.3 0 0 4 1 73 161 2023 0.2932 0 0.078391959798995 Adipocytokine signaling pathway(K)(0.9967066)-Alzheimer disease-amyloid secretase pathway(P)(0.9955516)-BMP receptor signaling(N)(0.984126)-Chagas disease(K)(0.9905118)-EGF receptor signaling pathway(P)(0.9736708)-Endothelins(N)(0.9788008)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9922336)-ErbB signaling pathway(K)(0.9737528)-FAS signaling pathway(P)(0.9829398)-Focal adhesion(K)(0.9992262)-FoxO family signaling(N)(0.9893906)-Glypican pathway(N)(0.9963502)-GnRH signaling pathway(K)(0.9947932)-Huntington disease(P)(0.9976522)-IFN-gamma pathway(N)(0.9927818)-IL1-mediated signaling events(N)(0.965114)-IL12-mediated signaling events(N)(0.9909434)-IL2-mediated signaling events(N)(0.9817018)-Insulin signaling pathway(K)(0.9980784)-Integrin signalling pathway(P)(0.9983202)-MAPK signaling pathway(K)(0.996215)-NOD-like receptor signaling pathway(K)(0.99321)-Neurotrophin signaling pathway(K)(0.9705364)-Oxidative stress response(P)(0.9527128)-Pathways in cancer(K)(0.9996228)-Plasma membrane estrogen receptor signaling(N)(0.9954896)-Progesterone-mediated oocyte maturation(K)(0.9955114)-Protein processing in endoplasmic reticulum(K)(0.9988712)-RIG-I-like receptor signaling pathway(K)(0.9951418)-Regulation of retinoblastoma protein(N)(0.994592)-Shigellosis(K)(0.9902474)-T cell receptor signaling pathway(K)(0.9556478)-TCR signaling in naive CD8+ T cells(N)(0.9883634)-TGF-beta signaling pathway(P)(0.9959732)-TNF receptor signaling pathway(N)(0.9663282)-TRAIL signaling pathway(N)(0.994384)-Toll-like receptor signaling pathway(K)(0.9931536)-Type II diabetes mellitus(K)(0.9657178)-Wnt signaling pathway(K)(0.9994084)-p75(NTR)-mediated signaling(N)(0.9982046) 147 PLD1 3q26.31 0 1 10 0 14 160 2094 0.2932 0 0.0251256281407035 Alpha-synuclein signaling(N)(0.984222)-Angiogenesis(P)(0.9903174)-EGFR1(C)(0.9983348)-Endocytosis(K)(0.9989682)-Ether lipid metabolism(K)(0.9644508)-Fc gamma R-mediated phagocytosis(K)(0.9957364)-Glycerophospholipid metabolism(K)(0.9923698)-GnRH signaling pathway(K)(0.9975356)-Metabolic pathways(K)(0.9993038)-Pathways in cancer(K)(0.9987304)-Plasma membrane estrogen receptor signaling(N)(0.9966874)-Proteogylcan syndecan-mediated signaling events(N)(0.9996008)-Ras Pathway(P)(0.9881474)-rac1 cell motility signaling pathway(B)(0.9825982) 148 MBTPS1 16q24.1 0 0 1 8 489 160 167 0.2932 0 0.500502512562814 Protein processing in endoplasmic reticulum(K)(0.9987638) 149 PARD6A 16q22.1 0 0 1 10 456 155 795 0.2979 0 0.469346733668342 Endocytosis(K)(0.9991108)-Glypican pathway(N)(0.99637)-IFN-gamma pathway(N)(0.9991062)-Tight junction(K)(0.9978234) 150 ABCG4 11q23.3 0 0 2 12 349 155 44 0.2979 0 0.364824120603015 ABC transporters(K)(0.9986274) 151 CTNNA3 10q21.3 0 0 3 7 149 152 886 0.3009 0 0.159798994974874 Adherens junction(K)(0.9933652)-Alzheimer disease-presenilin pathway(P)(0.9978634)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.99834)-Bacterial invasion of epithelial cells(K)(0.9961654)-Endometrial cancer(K)(0.9844654)-Leukocyte transendothelial migration(K)(0.997791)-Pathways in cancer(K)(0.9983206)-Tight junction(K)(0.9985294)-Wnt signaling pathway(P)(0.9986112) 152 RPL19 17q12 0 27 37 2 162 151 313 0.3009 0 0.229145728643216 Influenza Life Cycle(R)(0.997939)-Metabolism of proteins(R)(0.998252) 153 TGFB3 14q24.3 0 0 0 1 176 149 1395 0.3026 0 0.177889447236181 Amoebiasis(K)(0.997559)-Cell cycle(K)(0.9975002)-Chagas disease(K)(0.995753)-Chronic myeloid leukemia(K)(0.9831248)-Cytokine-cytokine receptor interaction(K)(0.9981676)-Dilated cardiomyopathy(K)(0.9894104)-Endocytosis(K)(0.9992764)-Formation of Platelet plug(R)(0.9990032)-Hypertrophic cardiomyopathy (HCM)(K)(0.9907002)-Leishmaniasis(K)(0.9958538)-MAPK signaling pathway(K)(0.9990188)-Malaria(K)(0.9962182)-Pathways in cancer(K)(0.998876)-Renal cell carcinoma(K)(0.9883838)-TGF-beta signaling pathway(K)(0.995693)-TGF-beta signaling pathway(P)(0.9971204)-TGFBR(C)(0.9973804)-alk in cardiac myocytes(B)(0.984042)-ctcf: first multivalent nuclear factor(B)(0.9898508)-signal transduction through il1r(B)(0.9898856)-tgf beta signaling pathway(B)(0.9812626) 154 MADCAM1 19p13.3 0 0 3 3 204 146 316 0.3045 0 0.21105527638191 Cell adhesion molecules (CAMs)(K)(0.9985274)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9977446)-Integrin cell surface interactions(R)(0.9984008)-Intestinal immune network for IgA production(K)(0.9984668)-a4b1 and a4b7 Integrin signaling(N)(0.9732832) 155 POLD3 11q13.4 0 6 19 3 128 142 1407 0.3045 0 0.15678391959799 Base excision repair(K)(0.9970604)-DNA Repair(R)(0.998592)-DNA Replication(R)(0.991504)-DNA replication(K)(0.9867248)-Homologous recombination(K)(0.9969012)-Metabolic pathways(K)(0.9987518)-Mismatch repair(K)(0.9939702)-Nucleotide excision repair(K)(0.9906144)-Purine metabolism(K)(0.9983828)-Pyrimidine metabolism(K)(0.9895518)-S Phase(R)(0.9974966)-Telomere Maintenance(R)(0.9973518) 156 RBL2 16q12.2 0 1 3 9 458 142 314 0.3045 0 0.473366834170854 Cell cycle(K)(0.9989496)-FoxO family signaling(N)(0.997306)-TGF-beta signaling pathway(K)(0.9977914)-TGFBR(C)(0.9984286)-mets affect on macrophage differentiation(B)(0.9981964) 157 DYNC2H1 11q22.3 0 1 1 14 348 142 304 0.3045 0 0.365829145728643 Huntington disease(P)(0.998414)-Phagosome(K)(0.9975476)-Vasopressin-regulated water reabsorption(K)(0.996887) 158 GSR 8p12 0 2 3 33 334 141 102 0.3045 0 0.373869346733668 Glutathione metabolism(K)(0.9974508)-Metablism of nucleotides(R)(0.9985714) 159 PDGFA 7p22.3 0 0 7 0 62 140 1362 0.3045 0 0.0693467336683417 Angiogenesis(P)(0.99731)-Cytokine-cytokine receptor interaction(K)(0.9986958)-Focal adhesion(K)(0.9965098)-Formation of Platelet plug(R)(0.9973806)-Gap junction(K)(0.9984624)-Glioma(K)(0.9873096)-MAPK signaling pathway(K)(0.99646)-Pathways in cancer(K)(0.99928)-Prostate cancer(K)(0.9927368)-Regulation of actin cytoskeleton(K)(0.9982582)-Signaling by PDGF(R)(0.993313)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9974624)-TNF receptor signaling pathway(N)(0.997223)-TRAIL signaling pathway(N)(0.9968636)-phospholipids as signalling intermediaries(B)(0.99245) 160 NOTCH1 9q34.3 0 0 5 1 141 139 376 0.3045 1 0.147738693467337 Alzheimer disease-presenilin pathway(P)(0.9983502)-Angiogenesis(P)(0.99844)-Dorso-ventral axis formation(K)(0.995101)-Generic Transcription Pathway(R)(0.9950422)-NOTCH(C)(0.9977946)-Notch signaling pathway(K)(0.9937824)-Presenilin action in Notch and Wnt signaling(N)(0.99741)-Prion diseases(K)(0.9952306)-Regulation of beta-cell development(R)(0.9980396) 161 OR4F21 8p23.3 0 0 0 17 322 139 211 0.3045 0 0.34070351758794 Olfactory Signaling Pathway(R)(0.9987978) 162 PCM1 8p22 0 1 4 31 356 137 83 0.3045 1 0.393969849246231 G2/M Transition(R)(0.998463) 163 MMP2 16q12.2 0 1 3 5 436 136 933 0.3045 0 0.447236180904523 Alzheimer disease-presenilin pathway(P)(0.9988622)-FOXM1 transcription factor network(N)(0.9965236)-GnRH signaling pathway(K)(0.9984222)-Integrins in angiogenesis(N)(0.9965948)-LPA receptor mediated events(N)(0.9985012)-Leukocyte transendothelial migration(K)(0.9975598)-Pathways in cancer(K)(0.9992056)-Plasma membrane estrogen receptor signaling(N)(0.9972876)-Proteogylcan syndecan-mediated signaling events(N)(0.996055)-Regulation of IGF Activity by IGFBP(R)(0.9939672)-amb2 Integrin signaling(N)(0.9960368) 164 BCMO1 16q23.2 0 0 2 17 514 136 1130 0.3045 0 0.535678391959799 Metabolic pathways(K)(0.9990222)-Retinol metabolism(K)(0.9992776) 165 COX10 17p12 0 0 2 4 435 135 1143 0.3045 0 0.44321608040201 Metabolic pathways(K)(0.999025)-Oxidative phosphorylation(K)(0.9977658)-Porphyrin and chlorophyll metabolism(K)(0.997668) 166 CDKN1B 12p13.1 0 1 3 5 115 134 1217 0.3045 0 0.124623115577889 Cell Cycle Checkpoints(R)(0.9930118)-Cell cycle(K)(0.9977618)-DNA Replication(R)(0.948938)-ErbB signaling pathway(K)(0.9970216)-FOXA transcription factor networks(N)(0.9699414)-FoxO family signaling(N)(0.9907548)-G1/S Transition(R)(0.9927824)-Glypican pathway(N)(0.9947022)-Integrins in angiogenesis(N)(0.996662)-Interleukin signaling pathway(P)(0.9953342)-Pathways in cancer(K)(0.9982564)-Prostate cancer(K)(0.9959392)-Regulation of Telomerase(N)(0.9977472)-Regulation of retinoblastoma protein(N)(0.9934928)-Signalling by NGF(R)(0.998867)-TRAIL signaling pathway(N)(0.995706)-ctcf: first multivalent nuclear factor(B)(0.9907868) 167 GABARAP 17p13.1 0 0 0 4 395 134 46 0.3045 0 0.401005025125628 Regulation of autophagy(K)(0.9974724)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9983892) 168 ITGA1 5q11.2 0 0 1 0 121 131 720 0.3083 0 0.122613065326633 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9966714)-Dilated cardiomyopathy(K)(0.9977382)-ECM-receptor interaction(K)(0.9960286)-Focal adhesion(K)(0.9979444)-Hematopoietic cell lineage(K)(0.9981582)-Hypertrophic cardiomyopathy (HCM)(K)(0.9951468)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9960328)-Integrin cell surface interactions(R)(0.9979864)-Integrin signalling pathway(P)(0.9984474)-Regulation of actin cytoskeleton(K)(0.9985454)-Signaling events mediated by PRL(N)(0.9964262)-VEGFR3 signaling in lymphatic endothelium(N)(0.9810578)-agrin in postsynaptic differentiation(B)(0.9962708)-b cell survival pathway(B)(0.987802)-integrin signaling pathway(B)(0.9852402)-mcalpain and friends in cell motility(B)(0.9863614) 169 CNOT1 16q21 0 0 0 12 494 130 59 0.3083 0 0.508542713567839 RNA degradation(K)(0.999138) 170 MAP2K3 17p11.2 0 1 7 5 309 129 1380 0.3089 0 0.323618090452261 Amyotrophic lateral sclerosis (ALS)(K)(0.9965532)-Apoptosis signaling pathway(P)(0.9934592)-BMP receptor signaling(N)(0.9930014)-Cellular roles of Anthrax toxin(N)(0.9885662)-EGF receptor signaling pathway(P)(0.9936424)-EGFR1(C)(0.99899)-FGF signaling pathway(P)(0.9924212)-Fc epsilon RI signaling pathway(K)(0.9912216)-Glypican pathway(N)(0.9969178)-GnRH signaling pathway(K)(0.9971134)-IFN-gamma pathway(N)(0.9961764)-IL1-mediated signaling events(N)(0.9844622)-IL12-mediated signaling events(N)(0.996426)-Integrin signalling pathway(P)(0.9988518)-MAPK signaling pathway(K)(0.9987152)-Oxidative stress response(P)(0.9813034)-Plasma membrane estrogen receptor signaling(N)(0.9982422)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9943434)-TGFBR(C)(0.9976368)-TNF receptor signaling pathway(N)(0.9963756)-Toll-like receptor signaling pathway(K)(0.9990448)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9906598)-keratinocyte differentiation(B)(0.9880722)-mapkinase signaling pathway(B)(0.9748484)-p75(NTR)-mediated signaling(N)(0.9982912)-the 41bb-dependent immune response(B)(0.9799724) 171 COX4I1 16q24.1 0 0 2 11 493 124 1371 0.3155 0 0.508542713567839 Alzheimer's disease(K)(0.9983026)-Cardiac muscle contraction(K)(0.9984812)-Glucose Regulation of Insulin Secretion(R)(0.9978414)-Huntington's disease(K)(0.9987066)-Metabolic pathways(K)(0.9990242)-Oxidative phosphorylation(K)(0.9967496)-Parkinson's disease(K)(0.997411) 172 CRK 17p13.3 0 0 2 10 407 124 1575 0.3155 0 0.421105527638191 Angiogenesis(P)(0.9810108)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9901268)-Bacterial invasion of epithelial cells(K)(0.9740266)-Chemokine signaling pathway(K)(0.9989066)-EGFR1(C)(0.9972742)-Endothelins(N)(0.991328)-EphrinB-EPHB pathway(N)(0.9487986)-ErbB signaling pathway(K)(0.980401)-Fc gamma R-mediated phagocytosis(K)(0.997098)-Focal adhesion(K)(0.996554)-Formation of Platelet plug(R)(0.9980688)-Insulin signaling pathway(K)(0.9972938)-Integrin cell surface interactions(R)(0.9951184)-Integrin signalling pathway(P)(0.9978332)-KitReceptor(C)(0.9782952)-LPA receptor mediated events(N)(0.9862566)-MAPK signaling pathway(K)(0.9985568)-Nectin adhesion pathway(N)(0.9968996)-Neurotrophin signaling pathway(K)(0.9941378)-Pathways in cancer(K)(0.9996934)-Plasma membrane estrogen receptor signaling(N)(0.9983314)-Proteogylcan syndecan-mediated signaling events(N)(0.995342)-Regulation of actin cytoskeleton(K)(0.9986896)-Shigellosis(K)(0.9907674)-Signaling by PDGF(R)(0.9709416)-Signaling events mediated by PTP1B(N)(0.9963258)-Signaling events regulated by Ret tyrosine kinase(N)(0.9916374)-Signalling by NGF(R)(0.9976476)-TCR signaling in naive CD4+ T cells(N)(0.9952374)-p75(NTR)-mediated signaling(N)(0.998799) 173 RARS2 6q15 0 0 0 4 264 122 41 0.3155 0 0.269346733668342 Aminoacyl-tRNA biosynthesis(K)(0.9980322) 174 HSD17B2 16q23.3 0 0 0 6 520 122 1132 0.3155 0 0.528643216080402 Metabolic pathways(K)(0.9987064)-Steroid hormone biosynthesis(K)(0.998561) 175 CTDSPL 3p22.2 0 0 0 0 148 122 551 0.3155 0 0.148743718592965 BMP receptor signaling(N)(0.9973656)-Glypican pathway(N)(0.9986826)-IFN-gamma pathway(N)(0.9975806) 176 CACNA1B 9q34.3 0 0 2 1 170 120 597 0.3161 0 0.173869346733668 Calcium signaling pathway(K)(0.9993548)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.998668)-MAPK signaling pathway(K)(0.9966346)-Synaptic Transmission(R)(0.997836)-Taste transduction(K)(0.9979376)-Type II diabetes mellitus(K)(0.9952378) 177 ARRB1 11q13.4 0 8 25 6 116 119 1284 0.3161 0 0.155778894472362 Chemokine signaling pathway(K)(0.9984328)-Endocytosis(K)(0.9988732)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9987526)-MAPK signaling pathway(K)(0.9995218)-Membrane Trafficking(R)(0.9982154)-Phototransduction(K)(0.9954408)-Plasma membrane estrogen receptor signaling(N)(0.997734)-Proteogylcan syndecan-mediated signaling events(N)(0.9981026)-Wnt signaling pathway(P)(0.9985212)-Wnt(C)(0.9971446)-visual signal transduction(B)(0.9952344)-ß-arrestins in gpcr desensitization(B)(0.9517002) 178 F2R 5q13.3 0 0 0 2 148 119 995 0.3161 0 0.150753768844221 Calcium signaling pathway(K)(0.9982708)-Class A/1 (Rhodopsin-like receptors)(R)(0.9959322)-Complement and coagulation cascades(K)(0.9977296)-Endocytosis(K)(0.9985394)-Formation of Platelet plug(R)(0.9979348)-Neuroactive ligand-receptor interaction(K)(0.9990554)-Regulation of actin cytoskeleton(K)(0.9983648)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9874428)-fibrinolysis pathway(B)(0.9900752)-intrinsic prothrombin activation pathway(B)(0.995614)-thrombin signaling and protease-activated receptors(B)(0.9958836) 179 HSD17B4 5q23.1 0 0 0 0 132 118 1259 0.3161 0 0.132663316582915 Metabolic pathways(K)(0.9971924)-Metabolism of lipids and lipoproteins(R)(0.9988394)-Peroxisome(K)(0.9977934)-Primary bile acid biosynthesis(K)(0.8634178)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9969902) 180 PRKG1 10q11.23 0 0 1 3 131 117 1348 0.3161 0 0.135678391959799 BMP receptor signaling(N)(0.9968926)-Endothelin signaling pathway(P)(0.9834694)-Gap junction(K)(0.9957446)-Glypican pathway(N)(0.997912)-IFN-gamma pathway(N)(0.9965426)-IL1-mediated signaling events(N)(0.9952996)-Long-term depression(K)(0.9931354)-Olfactory transduction(K)(0.9981358)-Plasma membrane estrogen receptor signaling(N)(0.993915)-Salivary secretion(K)(0.9969624)-TNF receptor signaling pathway(N)(0.99607)-Thromboxane A2 receptor signaling(N)(0.992861)-Vascular smooth muscle contraction(K)(0.9989764)-actions of nitric oxide in the heart(B)(0.9907258)-ion channels and their functional role in vascular endothelium(B)(0.993377) 181 BRCA1 17q21.31 0 2 2 3 233 116 535 0.3161 1 0.241206030150754 Androgen-mediated signaling(N)(0.9749702)-AndrogenReceptor(C)(0.9961716)-BARD1 signaling events(N)(0.9977128)-DNA Repair(R)(0.9986938)-FOXA transcription factor networks(N)(0.9494472)-Signaling by Aurora kinases(N)(0.9818262)-Ubiquitin mediated proteolysis(K)(0.9982458)-atm signaling pathway(B)(0.9869774)-cell cycle: g2/m checkpoint(B)(0.9948674)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.996819) 182 NUP98 11p15.4 0 0 1 8 180 116 512 0.3161 1 0.189949748743719 HIV Life Cycle(R)(0.993835)-Host Interactions of HIV factors(R)(0.9986124)-Influenza Life Cycle(R)(0.9983658)-M Phase(R)(0.9973836)-Metabolism of carbohydrates(R)(0.9969046)-Metabolism of non-coding RNA(R)(0.9939696)-Transport of Mature Transcript to Cytoplasm(R)(0.9938342) 183 LAMA2 6q22.33 0 2 7 1 208 115 775 0.3161 0 0.219095477386935 Amoebiasis(K)(0.9988548)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9985326)-Dilated cardiomyopathy(K)(0.9962124)-ECM-receptor interaction(K)(0.995769)-Focal adhesion(K)(0.9989062)-Hypertrophic cardiomyopathy (HCM)(K)(0.9907014)-Integrin cell surface interactions(R)(0.9971874)-Integrin signalling pathway(P)(0.9992916)-Pathways in cancer(K)(0.998594)-Viral myocarditis(K)(0.997328)-a6b1 and a6b4 Integrin signaling(N)(0.9957204)-agrin in postsynaptic differentiation(B)(0.9965774)-prion pathway(B)(0.9862776) 184 POLR3D 8p21.3 0 1 1 29 357 114 1344 0.3161 0 0.389949748743719 Cytosolic DNA-sensing pathway(K)(0.9959138)-Metabolic pathways(K)(0.9990568)-Purine metabolism(K)(0.997529)-Pyrimidine metabolism(K)(0.9974128)-Transcription(R)(0.998199) 185 NCOR2 12q24.31 0 0 7 0 114 113 447 0.3161 0 0.121608040201005 AndrogenReceptor(C)(0.9985958)-Huntington disease(P)(0.9993116)-NOTCH(C)(0.997084)-NR transcription pathway(R)(0.9972304)-Notch signaling pathway(K)(0.9963934)-Notch signaling pathway(P)(0.8114146)-Retinoic acid receptors-mediated signaling(N)(0.9944868)-Signaling events mediated by HDAC Class I(N)(0.9979826)-map kinase inactivation of smrt corepressor(B)(0.9898776)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9963488)-mets affect on macrophage differentiation(B)(0.9935404)-nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells(B)(0.9947404) 186 CHEK1 11q24.2 0 0 0 11 368 111 247 0.3161 0 0.380904522613065 Cell Cycle Checkpoints(R)(0.9964172)-Cell cycle(K)(0.999541)-Circadian rhythm pathway(N)(0.9950586)-p53 signaling pathway(K)(0.998694) 187 PRKCZ 1p36.33 0 0 1 2 208 111 1772 0.3161 0 0.212060301507538 Alzheimer disease-amyloid secretase pathway(P)(0.9937082)-BMP receptor signaling(N)(0.9956902)-Chemokine signaling pathway(K)(0.9977238)-EGF receptor signaling pathway(P)(0.9886486)-EGFR1(C)(0.9983114)-Endocytosis(K)(0.9969594)-Endothelin signaling pathway(P)(0.963587)-Endothelins(N)(0.9908838)-FGF signaling pathway(P)(0.994525)-Glypican pathway(N)(0.997846)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9957988)-IFN-gamma pathway(N)(0.9965352)-IL1-mediated signaling events(N)(0.9927876)-IL2-mediated signaling events(N)(0.9812044)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.996361)-Insulin signaling pathway(K)(0.9962606)-Plasma membrane estrogen receptor signaling(N)(0.9669896)-Proteogylcan syndecan-mediated signaling events(N)(0.9977932)-Sphingosine 1-phosphate (S1P) pathway(N)(0.992189)-TNF alpha/NF-kB(C)(0.9988128)-TNF receptor signaling pathway(N)(0.9938582)-TRAIL signaling pathway(N)(0.991022)-Thromboxane A2 receptor signaling(N)(0.9906722)-Tight junction(K)(0.9986172)-Type II diabetes mellitus(K)(0.9878608)-Wnt signaling pathway(P)(0.9993904)-p75(NTR)-mediated signaling(N)(0.9978878) 188 PIGK 1p31.1 0 1 1 1 154 111 1304 0.3161 0 0.157788944723618 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.962168)-Metabolic pathways(K)(0.998853)-Metabolism of proteins(R)(0.998175) 189 ATP5C1 10p14 0 0 12 1 59 111 1338 0.3161 0 0.0723618090452261 Alzheimer's disease(K)(0.9986276)-Glucose Regulation of Insulin Secretion(R)(0.9970736)-Huntington's disease(K)(0.9988172)-Metablism of nucleotides(R)(0.9969116)-Metabolic pathways(K)(0.9980648)-Oxidative phosphorylation(K)(0.9980148)-Parkinson's disease(K)(0.9976852) 190 HRAS 11p15.5 0 0 1 1 160 109 2199 0.3161 1 0.162814070351759 Axon guidance(K)(0.9992082)-B cell receptor signaling pathway(K)(0.9845984)-Cell surface interactions at the vascular wall(R)(0.9981678)-Chemokine signaling pathway(K)(0.997837)-EGFR1(C)(0.9943064)-Endocytosis(K)(0.9994724)-Endothelins(N)(0.9921856)-ErbB signaling pathway(K)(0.9854016)-Fc-epsilon receptor I signaling in mast cells(N)(0.9875848)-Focal adhesion(K)(0.9981994)-Gap junction(K)(0.99684)-Glypican pathway(N)(0.9883062)-GnRH signaling pathway(K)(0.9900792)-IL2-mediated signaling events(N)(0.9663504)-Insulin signaling pathway(K)(0.9949986)-Integrin signalling pathway(P)(0.9988544)-KitReceptor(C)(0.9671808)-LPA receptor mediated events(N)(0.9800764)-Long-term depression(K)(0.9926482)-Long-term potentiation(K)(0.9876846)-MAPK signaling pathway(K)(0.9989424)-Natural killer cell mediated cytotoxicity(K)(0.9971758)-Nectin adhesion pathway(N)(0.9941886)-Neurotrophin signaling pathway(K)(0.9941354)-Pathways in cancer(K)(0.9981748)-Plasma membrane estrogen receptor signaling(N)(0.944373)-Prostate cancer(K)(0.9815786)-Proteogylcan syndecan-mediated signaling events(N)(0.9956918)-Regulation of actin cytoskeleton(K)(0.9975396)-Signaling by EGFR(R)(0.9742758)-Signaling by PDGF(R)(0.846051)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9877846)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9382086)-Signaling events regulated by Ret tyrosine kinase(N)(0.9938058)-Signalling by NGF(R)(0.9967836)-Sphingosine 1-phosphate (S1P) pathway(N)(0.987953)-T cell receptor signaling pathway(K)(0.9015788)-TCR signaling in naive CD4+ T cells(N)(0.9913884)-TRAIL signaling pathway(N)(0.98653)-Tight junction(K)(0.9962464)-a6b1 and a6b4 Integrin signaling(N)(0.95945)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9589612)-how progesterone initiates the oocyte maturation(B)(0.976866)-il-2 receptor beta chain in t cell activation(B)(0.9917324)-integrin signaling pathway(B)(0.9881336)-map kinase inactivation of smrt corepressor(B)(0.9703706)-mets affect on macrophage differentiation(B)(0.9941768)-nfat and hypertrophy of the heart (B)(0.9957654)-p38 mapk signaling pathway(B)(0.9814578)-p75(NTR)-mediated signaling(N)(0.9949446)-role of erbb2 in signal transduction and oncology(B)(0.9667688)-t cell receptor signaling pathway(B)(0.9373142)-the igf-1 receptor and longevity(B)(0.978901)-tpo signaling pathway(B)(0.9508294)-trefoil factors initiate mucosal healing(B)(0.8070224) 191 MAN1B1 9q34.3 0 0 5 0 138 109 1281 0.3161 0 0.143718592964824 Metabolic pathways(K)(0.9981702)-N-Glycan biosynthesis(K)(0.9982934)-Protein processing in endoplasmic reticulum(K)(0.9986226)-er associated degradation (erad) pathway(B)(0.996002) 192 CSF3 17q21.1 0 40 39 2 152 109 413 0.3161 0 0.234170854271357 Cytokine-cytokine receptor interaction(K)(0.9989938)-Hematopoietic cell lineage(K)(0.9970598)-Jak-STAT signaling pathway(K)(0.9988348)-Malaria(K)(0.9983104) 193 ACOT7 1p36.31 0 0 0 2 230 108 21 0.317 0 0.233165829145729 Biosynthesis of unsaturated fatty acids(K)(0.9994016) 194 PDGFRB 5q33.1 0 0 1 0 102 105 1235 0.3212 1 0.103517587939698 Angiogenesis(P)(0.9963786)-Calcium signaling pathway(K)(0.9978128)-Cytokine-cytokine receptor interaction(K)(0.9984676)-Focal adhesion(K)(0.996494)-Gap junction(K)(0.998107)-MAPK signaling pathway(K)(0.9985298)-Nectin adhesion pathway(N)(0.9939054)-Pathways in cancer(K)(0.9978616)-Prostate cancer(K)(0.9940808)-Regulation of actin cytoskeleton(K)(0.9980284)-Signaling by PDGF(R)(0.9944638)-Signaling events mediated by PTP1B(N)(0.9956292)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9971084) 195 CDC40 6q21 0 0 2 4 224 105 306 0.3212 0 0.231155778894472 Formation and Maturation of mRNA Transcript(R)(0.9948698)-Spliceosome(K)(0.9973276)-Transcription(R)(0.9981232)-Transport of Mature Transcript to Cytoplasm(R)(0.9947026) 196 ME1 6q14.2 0 1 1 3 253 103 1198 0.3225 0 0.25929648241206 Metabolic pathways(K)(0.9991792)-PPAR signaling pathway(K)(0.9989392)-Pyruvate metabolism(K)(0.9972322)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.996071) 197 XIAP 23q25 0 0 2 10 206 102 1232 0.3225 0 0.219095477386935 Apoptosis(K)(0.99747)-Apoptosis(R)(0.999333)-BMP receptor signaling(N)(0.9952688)-Focal adhesion(K)(0.9982594)-Glypican pathway(N)(0.9977254)-IFN-gamma pathway(N)(0.9929866)-NOD-like receptor signaling pathway(K)(0.9963764)-Pathways in cancer(K)(0.9977884)-TNF receptor signaling pathway(N)(0.9941786)-Ubiquitin mediated proteolysis(K)(0.9987264)-p75(NTR)-mediated signaling(N)(0.996983) 198 P2RY8 23p22.33 0 0 2 11 234 102 272 0.3225 1 0.248241206030151 Neuroactive ligand-receptor interaction(K)(0.99744) 199 F7 13q34 0 1 3 6 250 101 272 0.3225 0 0.261306532663317 Complement and coagulation cascades(K)(0.9989056)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.996988)-Metabolism of proteins(R)(0.9993366) 200 HSPA5 9q33.3 0 0 2 0 154 101 418 0.3225 0 0.15678391959799 Antigen processing and presentation(K)(0.9978056)-Apoptosis signaling pathway(P)(0.99839)-Further platelet releasate(R)(0.9867318)-Parkinson disease(P)(0.9973834)-Prion diseases(K)(0.9973268)-Protein export(K)(0.9952334)-Protein processing in endoplasmic reticulum(K)(0.998905)-prion pathway(B)(0.9977056) 201 HS3ST3A1 17p12 0 0 1 8 439 100 26 0.3225 0 0.450251256281407 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9981752) 202 IGKC NA 0 0 0 0 75 100 178 0.3225 0 0.0753768844221105 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.999451)-Innate Immunity Signaling(R)(0.99809) 203 ALDH7A1 5q23.2 0 0 1 2 147 99 1188 0.3225 0 0.150753768844221 Fatty acid metabolism(K)(0.9961856)-Glycerolipid metabolism(K)(0.9737988)-Glycine, serine and threonine metabolism(K)(0.9969092)-Histidine metabolism(K)(0.9944366)-Lysine degradation(K)(0.999459)-Metabolic pathways(K)(0.9991984)-Pyruvate metabolism(K)(0.9978304)-Tryptophan metabolism(K)(0.9964208) 204 ST3GAL2 16q22.1 0 0 1 8 477 99 1128 0.3225 0 0.488442211055276 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.9978594)-Glycosphingolipid biosynthesis - globo series(K)(0.9640858)-Metabolic pathways(K)(0.998755) 205 FAS 10q23.31 0 0 0 2 137 98 1232 0.3225 0 0.139698492462312 Alzheimer's disease(K)(0.998128)-Apoptosis signaling pathway(P)(0.993773)-Apoptosis(K)(0.995518)-Apoptosis(R)(0.9983734)-Autoimmune thyroid disease(K)(0.992176)-Chagas disease(K)(0.9969912)-Cytokine-cytokine receptor interaction(K)(0.9990916)-FAS signaling pathway (CD95)(N)(0.9929826)-FAS signaling pathway(P)(0.990487)-MAPK signaling pathway(K)(0.9981)-Natural killer cell mediated cytotoxicity(K)(0.9977778)-Pathways in cancer(K)(0.996418)-Type I diabetes mellitus(K)(0.995842)-il-2 receptor beta chain in t cell activation(B)(0.9931496)-keratinocyte differentiation(B)(0.9970876)-p53 pathway(P)(0.9847036)-p53 signaling pathway(K)(0.9979636) 206 MYO6 6q14.1 0 0 0 2 233 98 166 0.3225 0 0.236180904522613 Gap junction trafficking and regulation(R)(0.997144)-Nectin adhesion pathway(N)(0.9982464)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9992) 207 SSTR3 22q13.1 0 1 0 2 289 97 490 0.3236 0 0.293467336683417 Class A/1 (Rhodopsin-like receptors)(R)(0.997562)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.999099)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9978286)-Neuroactive ligand-receptor interaction(K)(0.9989642)-Receptor-ligand complexes bind G proteins(R)(0.997856) 208 NDUFC2 11q14.1 0 30 38 5 134 95 1332 0.3279 0 0.208040201005025 Alzheimer's disease(K)(0.9984476)-Glucose Regulation of Insulin Secretion(R)(0.9968594)-Huntington's disease(K)(0.9989286)-Metabolic pathways(K)(0.9976762)-Oxidative phosphorylation(K)(0.991478)-Parkinson's disease(K)(0.9974612) 209 ZFPM1 16q24.2 0 0 2 12 475 94 97 0.328 0 0.491457286432161 Signaling events mediated by HDAC Class I(N)(0.9988228) 210 BCAT1 12p12.1 0 3 4 1 76 93 1223 0.328 0 0.0844221105527638 Metabolic pathways(K)(0.9995212)-Metabolism of amino acids(R)(0.997829)-Pantothenate and CoA biosynthesis(K)(0.9766054)-Synaptic Transmission(R)(0.9992694)-Valine, leucine and isoleucine biosynthesis(K)(0.9969742) 211 PIGX 3q29 0 0 2 0 58 93 1304 0.328 0 0.0603015075376884 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.9628706)-Metabolic pathways(K)(0.9985828)-Metabolism of proteins(R)(0.9992962) 212 PGR 11q22.1 0 1 3 11 328 92 193 0.328 0 0.344723618090452 NR transcription pathway(R)(0.9962068)-Oocyte meiosis(K)(0.9992288)-Progesterone-mediated oocyte maturation(K)(0.9989468)-how progesterone initiates the oocyte maturation(B)(0.9975184) 213 GTF2A1 14q31.1 0 0 0 2 174 91 288 0.328 0 0.176884422110553 Basal transcription factors(K)(0.9972278)-Formation and Maturation of mRNA Transcript(R)(0.997527)-HIV Life Cycle(R)(0.9973934)-Transcription(R)(0.9992196)-carm1 and regulation of the estrogen receptor(B)(0.9954566)-nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells(B)(0.9924188)-the information processing pathway at the ifn beta enhancer(B)(0.9977942) 214 TNF 6p21.33 0 0 3 1 76 90 2409 0.328 0 0.0804020100502513 Adipocytokine signaling pathway(K)(0.9957918)-Alzheimer's disease(K)(0.9984456)-Amoebiasis(K)(0.9964694)-Amyotrophic lateral sclerosis (ALS)(K)(0.9944224)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9788502)-Antigen processing and presentation(K)(0.993088)-Apoptosis signaling pathway(P)(0.9532908)-Apoptosis(K)(0.9870186)-Apoptosis(R)(0.998643)-Asthma(K)(0.9732542)-BMP receptor signaling(N)(0.992168)-Chagas disease(K)(0.9766938)-Cytokine-cytokine receptor interaction(K)(0.9985842)-Dilated cardiomyopathy(K)(0.9828876)-Endothelins(N)(0.9879844)-Glypican pathway(N)(0.9952846)-Hematopoietic cell lineage(K)(0.9950508)-IFN-gamma pathway(N)(0.9942358)-IL1-mediated signaling events(N)(0.95923)-IL12-mediated signaling events(N)(0.982899)-IL2-mediated signaling events(N)(0.9906114)-LPA receptor mediated events(N)(0.9790446)-Leishmaniasis(K)(0.963053)-MAPK signaling pathway(K)(0.9982236)-Malaria(K)(0.9885002)-NOD-like receptor signaling pathway(K)(0.9911802)-Natural killer cell mediated cytotoxicity(K)(0.997486)-Plasma membrane estrogen receptor signaling(N)(0.989274)-RIG-I-like receptor signaling pathway(K)(0.9951078)-Retinoic acid receptors-mediated signaling(N)(0.9874788)-Signaling by Aurora kinases(N)(0.9750994)-Signaling events mediated by HDAC Class I(N)(0.9964094)-Signaling events regulated by Ret tyrosine kinase(N)(0.9801298)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9974616)-Systemic lupus erythematosus(K)(0.9975708)-T cell receptor signaling pathway(K)(0.9882486)-TCR signaling in naive CD4+ T cells(N)(0.9833572)-TGF-beta signaling pathway(K)(0.997628)-TNF alpha/NF-kB(C)(0.9979444)-TNF receptor signaling pathway(N)(0.9896352)-Toll-like receptor signaling pathway(K)(0.9936564)-Type I diabetes mellitus(K)(0.9792776)-Type II diabetes mellitus(K)(0.9893208)-Wnt signaling pathway(P)(0.9977042)-amb2 Integrin signaling(N)(0.9927364)-il-10 anti-inflammatory signaling pathway(B)(0.9639818)-keratinocyte differentiation(B)(0.9589776)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9923406)-nfat and hypertrophy of the heart (B)(0.9845858)-p75(NTR)-mediated signaling(N)(0.9973246) 215 DGKH 13q14.11 0 0 1 9 298 90 1164 0.328 0 0.309547738693467 Glycerolipid metabolism(K)(0.974557)-Glycerophospholipid metabolism(K)(0.9966632)-Metabolic pathways(K)(0.9993392)-Phosphatidylinositol signaling system(K)(0.9984624) 216 GBE1 3p12.2 0 0 2 0 146 90 1183 0.328 0 0.148743718592965 Metabolic pathways(K)(0.999582)-Metabolism of carbohydrates(R)(0.999094)-Starch and sucrose metabolism(K)(0.996025) 217 ARHGEF7 13q34 0 0 3 6 250 90 902 0.328 0 0.260301507537688 Glypican pathway(N)(0.996788)-Regulation of actin cytoskeleton(K)(0.997536)-Signaling by Aurora kinases(N)(0.9898008)-Signaling by EGFR(R)(0.9929518)-Signaling by Rho GTPases(R)(0.99897)-TRAIL signaling pathway(N)(0.9988678)-agrin in postsynaptic differentiation(B)(0.9976098) 218 NEIL2 8p23.1 0 0 1 25 347 89 34 0.3281 0 0.374874371859297 Base excision repair(K)(0.9992036) 219 PSD3 8p22 0 0 3 33 368 88 204 0.3281 0 0.406030150753769 Endocytosis(K)(0.998358) 220 GUCY1A2 11q22.3 0 0 0 12 355 87 430 0.3281 0 0.368844221105528 Gap junction(K)(0.9984382)-Long-term depression(K)(0.9967876)-Purine metabolism(K)(0.9993382)-Salivary secretion(K)(0.9980436)-Vascular smooth muscle contraction(K)(0.9992592)-actions of nitric oxide in the heart(B)(0.997011)-ion channels and their functional role in vascular endothelium(B)(0.9969692) 221 C8G 9q34.3 0 0 5 0 141 86 380 0.3281 0 0.146733668341709 Amoebiasis(K)(0.9986808)-Complement and coagulation cascades(K)(0.9987458)-Innate Immunity Signaling(R)(0.9979272)-Prion diseases(K)(0.9971444)-Systemic lupus erythematosus(K)(0.999324) 222 APC 5q22.2 0 0 0 2 145 86 1228 0.3281 1 0.147738693467337 Angiogenesis(P)(0.9970772)-Apoptosis(R)(0.9979246)-Glypican pathway(N)(0.9977484)-Pathways in cancer(K)(0.998309)-Presenilin action in Notch and Wnt signaling(N)(0.9967336)-Regulation of actin cytoskeleton(K)(0.9985104)-Wnt signaling pathway(K)(0.9950432)-Wnt signaling pathway(P)(0.998037)-Wnt(C)(0.9972652) 223 OR13D1 9q31.1 0 0 0 1 162 86 389 0.3281 0 0.163819095477387 Olfactory transduction(K)(0.9973752) 224 SLC2A4 17p13.1 0 0 0 4 395 85 637 0.3281 0 0.401005025125628 Adipocytokine signaling pathway(K)(0.997434)-Insulin signaling pathway(K)(0.9978886)-Metabolism of carbohydrates(R)(0.9986902)-Metabolism of vitamins and cofactors(R)(0.9950254)-Plasma membrane estrogen receptor signaling(N)(0.9992676)-Proteogylcan syndecan-mediated signaling events(N)(0.9963842)-Type II diabetes mellitus(K)(0.995106) 225 RAD50 5q31.1 0 0 0 1 120 85 187 0.3281 0 0.121608040201005 BARD1 signaling events(N)(0.998389)-DNA Repair(R)(0.9987164)-Homologous recombination(K)(0.9991552)-Non-homologous end-joining(K)(0.9957296)-Regulation of Telomerase(N)(0.998341)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9055488) 226 AMT 3p21.31 0 0 0 0 196 85 1142 0.3281 0 0.196984924623116 Glycine, serine and threonine metabolism(K)(0.9968752)-Metabolic pathways(K)(0.9975204)-Nitrogen metabolism(K)(0.9970386)-One carbon pool by folate(K)(0.9968026) 227 PIGQ 16p13.3 0 0 12 1 46 85 1304 0.3281 0 0.0592964824120603 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.958862)-Metabolic pathways(K)(0.998947)-Metabolism of proteins(R)(0.998842) 228 PCSK1 5q15 0 0 0 1 136 84 207 0.3299 0 0.137688442211055 Alzheimer disease-amyloid secretase pathway(P)(0.9992132)-Alzheimer disease-presenilin pathway(P)(0.9993938)-Insulin Synthesis and Secretion(R)(0.9993006) 229 ATP1B2 17p13.1 0 0 0 7 411 82 374 0.3352 0 0.420100502512563 Aldosterone-regulated sodium reabsorption(K)(0.9970436)-Cardiac muscle contraction(K)(0.9980618)-Cell surface interactions at the vascular wall(R)(0.9977518)-Gastric acid secretion(K)(0.997624)-Pancreatic secretion(K)(0.9988728)-Proximal tubule bicarbonate reclamation(K)(0.9900858)-Salivary secretion(K)(0.997069) 230 PGD 1p36.22 0 0 0 1 251 80 1211 0.3358 0 0.253266331658291 Glutathione metabolism(K)(0.9981316)-Metabolic pathways(K)(0.9984766)-Metabolism of carbohydrates(R)(0.9986814)-Pentose phosphate pathway(K)(0.9754724) 231 IL2RA 10p15.1 0 0 9 0 63 80 1302 0.3358 0 0.0723618090452261 BMP receptor signaling(N)(0.995859)-Cytokine-cytokine receptor interaction(K)(0.9986358)-Endocytosis(K)(0.9981558)-Endothelins(N)(0.9956248)-Glypican pathway(N)(0.9972138)-Hematopoietic cell lineage(K)(0.9970396)-IFN-gamma pathway(N)(0.9984028)-IL1-mediated signaling events(N)(0.9960756)-IL12-mediated signaling events(N)(0.989237)-IL2-mediated signaling events(N)(0.9585174)-Jak-STAT signaling pathway(K)(0.9984454)-Plasma membrane estrogen receptor signaling(N)(0.9976188)-Proteogylcan syndecan-mediated signaling events(N)(0.9985608)-TCR signaling in naive CD4+ T cells(N)(0.9930078)-TNF receptor signaling pathway(N)(0.996278)-TRAIL signaling pathway(N)(0.973671)-il-2 receptor beta chain in t cell activation(B)(0.9945418) 232 PTK2B 8p21.2 0 0 1 29 349 80 1219 0.3358 0 0.380904522613065 Alpha-synuclein signaling(N)(0.9911166)-Calcium signaling pathway(K)(0.997939)-Chemokine signaling pathway(K)(0.99946)-EGFR1(C)(0.9983232)-Endothelins(N)(0.9980128)-GnRH signaling pathway(K)(0.994419)-IL2-mediated signaling events(N)(0.9936446)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9894378)-Integrin signalling pathway(P)(0.997797)-Integrins in angiogenesis(N)(0.99665)-LPA receptor mediated events(N)(0.9942188)-Leukocyte transendothelial migration(K)(0.9974896)-Natural killer cell mediated cytotoxicity(K)(0.9968168)-Proteogylcan syndecan-mediated signaling events(N)(0.998233)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9954152) 233 JUN 1p32.1 0 0 1 1 129 79 2127 0.3358 1 0.131658291457286 AndrogenReceptor(C)(0.9961714)-Angiogenesis(P)(0.9885356)-Apoptosis signaling pathway(P)(0.9745088)-B cell receptor signaling pathway(K)(0.9833342)-BMP receptor signaling(N)(0.989815)-Chagas disease(K)(0.9956488)-EGFR1(C)(0.996779)-Endothelins(N)(0.987469)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9935726)-ErbB signaling pathway(K)(0.9787608)-FAS signaling pathway(P)(0.9760426)-FOXA transcription factor networks(N)(0.9527096)-Fc-epsilon receptor I signaling in mast cells(N)(0.9818976)-Focal adhesion(K)(0.9994204)-Glypican pathway(N)(0.9970552)-GnRH signaling pathway(K)(0.994251)-Huntington disease(P)(0.9978612)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9985806)-IFN-gamma pathway(N)(0.9103822)-IL1-mediated signaling events(N)(0.974888)-IL12-mediated signaling events(N)(0.9874486)-IL2-mediated signaling events(N)(0.9878768)-IL6-mediated signaling events(N)(0.9914388)-Integrins in angiogenesis(N)(0.9938358)-LPA receptor mediated events(N)(0.9877562)-Leishmaniasis(K)(0.9856486)-MAPK signaling pathway(K)(0.9988982)-Neurotrophin signaling pathway(K)(0.9957816)-Oxidative stress response(P)(0.9494308)-Pathways in cancer(K)(0.9982456)-Plasma membrane estrogen receptor signaling(N)(0.9632132)-Presenilin action in Notch and Wnt signaling(N)(0.9408958)-Proteogylcan syndecan-mediated signaling events(N)(0.9983268)-Regulation of Telomerase(N)(0.996421)-Regulation of retinoblastoma protein(N)(0.992074)-Signaling events regulated by Ret tyrosine kinase(N)(0.979089)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9911838)-T cell receptor signaling pathway(K)(0.9519498)-TCR signaling in naive CD4+ T cells(N)(0.9880828)-TGF-beta signaling pathway(P)(0.9960626)-TGFBR(C)(0.9975656)-TNF receptor signaling pathway(N)(0.9843986)-TRAIL signaling pathway(N)(0.9820196)-Toll-like receptor signaling pathway(K)(0.9964928)-Wnt signaling pathway(K)(0.9976366)-agrin in postsynaptic differentiation(B)(0.9887788)-atm signaling pathway(B)(0.9549504)-erythropoietin mediated neuroprotection through nf-kb(B)(0.9282102)-keratinocyte differentiation(B)(0.9431184)-lectin induced complement pathway(B)(0.9765252)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9911628)-mets affect on macrophage differentiation(B)(0.9737386)-oxidative stress induced gene expression via nrf2(B)(0.985276)-repression of pain sensation by the transcriptional regulator dream(B)(0.9714878)-t cell receptor signaling pathway(B)(0.9801612)-the information processing pathway at the ifn beta enhancer(B)(0.9877908)-tpo signaling pathway(B)(0.9466682) 234 LIPF 10q23.31 0 0 0 4 147 79 1122 0.3358 0 0.151758793969849 Glycerolipid metabolism(K)(0.948785)-Metabolic pathways(K)(0.9996718) 235 TIAM2 6q25.2 0 0 0 5 224 79 469 0.3358 0 0.230150753768844 Chemokine signaling pathway(K)(0.9969596)-Regulation of actin cytoskeleton(K)(0.9997)-Signaling by Rho GTPases(R)(0.9995836) 236 MED31 17p13.2 0 0 0 4 414 77 33 0.3388 0 0.420100502512563 Generic Transcription Pathway(R)(0.9991492) 237 VAMP3 1p36.23 0 0 0 1 217 76 612 0.3388 0 0.219095477386935 5HT2 type receptor mediated signaling pathway(P)(0.9938468)-PNAT(P)(0.994387)-Phagosome(K)(0.9978976)-Plasma membrane estrogen receptor signaling(N)(0.9993754)-Proteogylcan syndecan-mediated signaling events(N)(0.9987332)-SNARE interactions in vesicular transport(K)(0.9971264) 238 ASMT 23p22.33 0 0 2 9 222 76 1126 0.3388 0 0.234170854271357 Metabolic pathways(K)(0.9985282)-Tryptophan metabolism(K)(0.99855) 239 JAK2 9p24.1 0 0 5 7 212 76 1036 0.3388 1 0.225125628140704 Adipocytokine signaling pathway(K)(0.9996168)-Chemokine signaling pathway(K)(0.9988024)-EGFR1(C)(0.9973836)-Endothelins(N)(0.9959928)-IFN-gamma pathway(N)(0.9980336)-IL12-mediated signaling events(N)(0.9984624)-IL23-mediated signaling events(N)(0.9899994)-IL6-mediated signaling events(N)(0.9948024)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9979794)-Jak-STAT signaling pathway(K)(0.9981512)-KitReceptor(C)(0.9876048)-Leishmaniasis(K)(0.9968018)-NOTCH(C)(0.9991402)-Signaling events mediated by PTP1B(N)(0.9963472)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9925544)-Sphingosine 1-phosphate (S1P) pathway(N)(0.996468)-a4b1 and a4b7 Integrin signaling(N)(0.9634842)-role of erbb2 in signal transduction and oncology(B)(0.9914344) 240 FOS 14q24.3 0 0 1 1 181 76 1881 0.3388 0 0.18391959798995 Androgen-mediated signaling(N)(0.9541586)-Angiogenesis(P)(0.9926674)-B cell receptor signaling pathway(K)(0.9792182)-BMP receptor signaling(N)(0.9937464)-Chagas disease(K)(0.9929504)-EGFR1(C)(0.9963308)-Endothelins(N)(0.9936132)-FOXA transcription factor networks(N)(0.950039)-FOXM1 transcription factor network(N)(0.9965458)-Fc-epsilon receptor I signaling in mast cells(N)(0.9925876)-Glypican pathway(N)(0.9942952)-Huntington disease(P)(0.9980034)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9859206)-IFN-gamma pathway(N)(0.9838304)-IL1-mediated signaling events(N)(0.9571464)-IL12-mediated signaling events(N)(0.9933674)-IL2-mediated signaling events(N)(0.9902314)-IL6-mediated signaling events(N)(0.9915296)-Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade(P)(0.9650936)-Integrins in angiogenesis(N)(0.9941208)-LPA receptor mediated events(N)(0.993167)-Leishmaniasis(K)(0.9897186)-MAPK signaling pathway(K)(0.9991698)-Pathways in cancer(K)(0.9993792)-Plasma membrane estrogen receptor signaling(N)(0.975692)-Presenilin action in Notch and Wnt signaling(N)(0.982013)-Proteogylcan syndecan-mediated signaling events(N)(0.9988944)-Regulation of Telomerase(N)(0.9963266)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9931476)-T cell receptor signaling pathway(K)(0.9819632)-TCR signaling in naive CD4+ T cells(N)(0.9926514)-TGF-beta signaling pathway(P)(0.995762)-TGFBR(C)(0.9971418)-TNF receptor signaling pathway(N)(0.9894376)-TRAIL signaling pathway(N)(0.9763672)-Toll-like receptor signaling pathway(K)(0.9985932)-bone remodeling(B)(0.9601242)-il-2 receptor beta chain in t cell activation(B)(0.9718312)-keratinocyte differentiation(B)(0.9698646)-mets affect on macrophage differentiation(B)(0.9795782)-oxidative stress induced gene expression via nrf2(B)(0.9917404)-p75(NTR)-mediated signaling(N)(0.9982324)-repression of pain sensation by the transcriptional regulator dream(B)(0.9758438)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.8079318)-t cell receptor signaling pathway(B)(0.9894154)-toll-like receptor pathway(B)(0.9635134)-tpo signaling pathway(B)(0.968194) 241 ALDH1A1 9q21.13 0 0 2 1 143 75 1151 0.3396 0 0.146733668341709 Biological oxidations(R)(0.9988252)-Metabolic pathways(K)(0.998678)-Retinol metabolism(K)(0.9974174) 242 SMPD3 16q22.1 0 0 0 9 485 75 1558 0.3396 0 0.496482412060302 Metabolic pathways(K)(0.998448)-Sphingolipid metabolism(K)(0.99634)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9977204)-TNF receptor signaling pathway(N)(0.9985172)-TRAIL signaling pathway(N)(0.9984792) 243 POLR3C 1q21.1 0 0 17 2 8 74 1229 0.3402 0 0.0271356783919598 Cytosolic DNA-sensing pathway(K)(0.998941)-Metabolic pathways(K)(0.9985704)-Purine metabolism(K)(0.9989328)-Pyrimidine metabolism(K)(0.9927056) 244 PHKB 16q12.1 0 0 3 10 448 74 491 0.3402 0 0.463316582914573 Calcium signaling pathway(K)(0.9985418)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9977604)-Insulin signaling pathway(K)(0.9962582)-Metabolism of carbohydrates(R)(0.9976662) 245 PSMD3 17q12 0 50 36 1 150 73 394 0.3413 0 0.238190954773869 APC/C-mediated degradation of cell cycle proteins(R)(0.9975566)-Apoptosis(R)(0.9990982)-Cell Cycle Checkpoints(R)(0.998111)-Cell cycle(P)(0.9761818)-G1/S Transition(R)(0.9963366)-Host Interactions of HIV factors(R)(0.9988746)-Metabolism of amino acids(R)(0.9983692)-Proteasome(K)(0.9938196)-S Phase(R)(0.9914086)-Signaling by Wnt(R)(0.9962392) 246 DYNC1LI2 16q22.1 0 0 0 12 509 73 304 0.3413 0 0.523618090452261 Huntington disease(P)(0.9981758)-Phagosome(K)(0.9993134)-Vasopressin-regulated water reabsorption(K)(0.9980218) 247 PRIM2 6p11.2 0 0 2 0 102 72 1321 0.3416 0 0.104522613065327 DNA replication(K)(0.994617)-G1/S Transition(R)(0.9982948)-Metabolic pathways(K)(0.9989748)-Purine metabolism(K)(0.9991392)-Pyrimidine metabolism(K)(0.9978232)-S Phase(R)(0.9881164)-Telomere Maintenance(R)(0.9980458) 248 CACNB1 17q12 0 26 36 2 163 72 435 0.3416 0 0.228140703517588 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.996341)-Cardiac muscle contraction(K)(0.995702)-Dilated cardiomyopathy(K)(0.9954542)-Hypertrophic cardiomyopathy (HCM)(K)(0.9964462)-MAPK signaling pathway(K)(0.9991814)-Synaptic Transmission(R)(0.996734) 249 CPT1B 22q13.33 0 0 2 3 276 71 290 0.3416 0 0.282412060301508 Activated AMPK stimulates fatty-acid oxidation in muscle(R)(0.9884262)-Adipocytokine signaling pathway(K)(0.9979504)-FOXA transcription factor networks(N)(0.964031)-Fatty acid metabolism(K)(0.9965186)-Metabolism of lipids and lipoproteins(R)(0.998129)-PPAR signaling pathway(K)(0.9976252) 250 SAP18 13q12.11 0 0 0 7 263 71 660 0.3416 0 0.271356783919598 Glypican pathway(N)(0.9994744)-Hedgehog signaling pathway(P)(0.906135)-Hedgehog(C)(0.99251)-IFN-gamma pathway(N)(0.9981054)-Regulation of Telomerase(N)(0.9966046)-Signaling events mediated by HDAC Class I(N)(0.9973062)-Signaling events mediated by the Hedgehog family(N)(0.995117) 251 MAS1 6q25.3 0 0 0 4 209 71 285 0.3416 0 0.214070351758794 Neuroactive ligand-receptor interaction(K)(0.9979962)-Renin-angiotensin system(K)(0.9981484) 252 CDKN2B 9p21.3 0 0 3 17 184 70 877 0.3419 0 0.205025125628141 Cell cycle(K)(0.9969964)-Glypican pathway(N)(0.9993678)-IFN-gamma pathway(N)(0.9978862)-Pathways in cancer(K)(0.9993434)-TGF-beta signaling pathway(K)(0.9977866) 253 NKD1 16q12.1 0 0 2 8 431 70 783 0.3419 0 0.44321608040201 Glypican pathway(N)(0.9960184)-Wnt signaling pathway(K)(0.9978456)-Wnt signaling pathway(P)(0.9981816)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9963098)-multi-step regulation of transcription by pitx2(B)(0.9838432)-segmentation clock(B)(0.9975698) 254 CTSD 11p15.5 0 0 0 0 172 69 574 0.3419 0 0.17286432160804 Lysosome(K)(0.9989424)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9979638)-TNF receptor signaling pathway(N)(0.998979)-TRAIL signaling pathway(N)(0.9978306)-downregulated of mta-3 in er-negative breast tumors(B)(0.9972866) 255 GP1BB 22q11.21 0 0 3 0 252 69 273 0.3419 0 0.256281407035176 ECM-receptor interaction(K)(0.9984986)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9979284)-Formation of Platelet plug(R)(0.9971662)-Hematopoietic cell lineage(K)(0.9991806) 256 TUSC3 8p22 0 2 4 34 352 69 1277 0.3419 0 0.393969849246231 Metabolic pathways(K)(0.9979692)-N-Glycan biosynthesis(K)(0.9957734)-Protein processing in endoplasmic reticulum(K)(0.998023) 257 RPL13 16q24.3 0 0 2 12 479 68 313 0.3446 0 0.495477386934673 Influenza Life Cycle(R)(0.9987394)-Metabolism of proteins(R)(0.997911) 258 GALC 14q31.3 0 0 0 3 183 67 1218 0.346 0 0.186934673366834 Lysosome(K)(0.9980152)-Metabolic pathways(K)(0.9988528)-Sphingolipid metabolism(K)(0.999069) 259 APH1A 1q21.2 0 3 20 0 12 66 798 0.346 0 0.0351758793969849 Alzheimer disease-amyloid secretase pathway(P)(0.991669)-Alzheimer disease-presenilin pathway(P)(0.9986228)-Alzheimer's disease(K)(0.9961582)-NOTCH(C)(0.9982656)-Notch signaling pathway(K)(0.9884922)-Notch signaling pathway(P)(0.8387854)-Presenilin action in Notch and Wnt signaling(N)(0.9897854)-Proteogylcan syndecan-mediated signaling events(N)(0.9983084)-Signalling by NGF(R)(0.997773)-p75(NTR)-mediated signaling(N)(0.9996372) 260 ROCK1 18q11.1 0 0 2 1 176 66 1257 0.346 0 0.179899497487437 Apoptosis(R)(0.9986418)-Axon guidance(K)(0.998723)-Chemokine signaling pathway(K)(0.998082)-EphrinA-EPHA pathway(N)(0.9111534)-EphrinB-EPHB pathway(N)(0.9683212)-Focal adhesion(K)(0.9980328)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.997744)-Integrins in angiogenesis(N)(0.9968406)-Leukocyte transendothelial migration(K)(0.9964316)-Nectin adhesion pathway(N)(0.9884062)-Pathogenic Escherichia coli infection(K)(0.9968714)-Regulation of actin cytoskeleton(K)(0.998826)-Shigellosis(K)(0.9849668)-Signaling events mediated by PRL(N)(0.993633)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9976562)-TGF-beta signaling pathway(K)(0.9973708)-TGFBR(C)(0.9986264)-Thromboxane A2 receptor signaling(N)(0.9922876)-Vascular smooth muscle contraction(K)(0.9987506)-Wnt signaling pathway(K)(0.9972638)-integrin signaling pathway(B)(0.9827016)-rho cell motility signaling pathway(B)(0.989197)-role of mal in rho-mediated activation of srf(B)(0.9743502)-thrombin signaling and protease-activated receptors(B)(0.9856934) 261 ABCC4 13q32.1 0 0 0 11 284 66 44 0.346 0 0.296482412060302 ABC transporters(K)(0.9990988) 262 TRAF2 9q34.3 0 0 4 0 139 65 1385 0.346 0 0.143718592964824 Adipocytokine signaling pathway(K)(0.997279)-Apoptosis(K)(0.9963066)-Apoptosis(R)(0.9959606)-BMP receptor signaling(N)(0.9958784)-Glypican pathway(N)(0.995786)-IFN-gamma pathway(N)(0.997198)-MAPK signaling pathway(K)(0.9981886)-Pathways in cancer(K)(0.9974164)-Protein processing in endoplasmic reticulum(K)(0.9977228)-RIG-I-like receptor signaling pathway(K)(0.9974474)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9929522)-TNF alpha/NF-kB(C)(0.9966496)-TNF receptor signaling pathway(N)(0.9965866)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9812854)-keratinocyte differentiation(B)(0.9933784)-p53 pathway(P)(0.988861)-the 41bb-dependent immune response(B)(0.9781586) 263 RANGAP1 22q13.2 0 0 1 2 297 65 367 0.346 0 0.301507537688442 HIV Life Cycle(R)(0.9964162)-Host Interactions of HIV factors(R)(0.9977384)-M Phase(R)(0.9985016)-Signaling events mediated by HDAC Class I(N)(0.9991166)-role of ran in mitotic spindle regulation(B)(0.9960616) 264 QARS 3p21.31 0 0 1 0 199 65 1161 0.346 0 0.201005025125628 Aminoacyl-tRNA biosynthesis(K)(0.9985832)-Metabolic pathways(K)(0.9991686)-tRNA Aminoacylation(R)(0.9956276) 265 ARAP3 5q31.3 0 0 0 0 105 65 812 0.346 0 0.105527638190955 Endocytosis(K)(0.9976476)-Glypican pathway(N)(0.996863)-Signaling by Rho GTPases(R)(0.9987342)-TRAIL signaling pathway(N)(0.9979536) 266 PER1 17p13.1 0 0 1 7 422 64 30 0.3474 1 0.4321608040201 Circadian rhythm - mammal(K)(0.998194)-Circadian rhythm pathway(N)(0.9978514) 267 YWHAE 17p13.3 0 0 0 10 412 64 1333 0.3474 0 0.424120603015075 BMP receptor signaling(N)(0.9943606)-Cell cycle(K)(0.9977794)-EGF receptor signaling pathway(P)(0.9916486)-Endothelins(N)(0.9900764)-FGF signaling pathway(P)(0.992486)-FoxO family signaling(N)(0.978413)-G2/M Transition(R)(0.9974794)-Glypican pathway(N)(0.9961846)-IFN-gamma pathway(N)(0.9971042)-IL1-mediated signaling events(N)(0.985978)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9950918)-Neurotrophin signaling pathway(K)(0.9924796)-Oocyte meiosis(K)(0.99671)-Parkinson disease(P)(0.9958922)-Plasma membrane estrogen receptor signaling(N)(0.9893146)-Proteogylcan syndecan-mediated signaling events(N)(0.9977616)-Regulation of Telomerase(N)(0.9979458)-Signaling events mediated by HDAC Class I(N)(0.9979716)-Signalling by NGF(R)(0.9983008)-TNF receptor signaling pathway(N)(0.9952922)-TRAIL signaling pathway(N)(0.9937238)-a6b1 and a6b4 Integrin signaling(N)(0.9926638)-p75(NTR)-mediated signaling(N)(0.998324) 268 BMP1 8p21.3 0 1 1 29 352 63 196 0.3474 0 0.384924623115578 Metabolism of lipids and lipoproteins(R)(0.998619)-TGF-beta signaling pathway(P)(0.998723) 269 POLA2 11q13.1 0 0 4 1 106 63 1321 0.3474 0 0.111557788944724 DNA replication(K)(0.9974636)-G1/S Transition(R)(0.9980986)-Metabolic pathways(K)(0.9996168)-Purine metabolism(K)(0.999186)-Pyrimidine metabolism(K)(0.9935982)-S Phase(R)(0.9957332)-Telomere Maintenance(R)(0.9974466) 270 ESR1 6q25.1 0 2 9 3 189 62 1003 0.3474 0 0.204020100502513 AndrogenReceptor(C)(0.9979238)-BMP receptor signaling(N)(0.994641)-FOXA transcription factor networks(N)(0.9811328)-FOXM1 transcription factor network(N)(0.9964878)-Glypican pathway(N)(0.9979664)-IFN-gamma pathway(N)(0.996687)-IL1-mediated signaling events(N)(0.991576)-Plasma membrane estrogen receptor signaling(N)(0.996069)-Regulation of Telomerase(N)(0.9968674)-Signaling events mediated by HDAC Class I(N)(0.9975004)-TGFBR(C)(0.998613)-TNF receptor signaling pathway(N)(0.9992224)-carm1 and regulation of the estrogen receptor(B)(0.9136136)-downregulated of mta-3 in er-negative breast tumors(B)(0.9925436)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.9878768)-role of erbb2 in signal transduction and oncology(B)(0.9918354) 271 TNFSF10 3q26.31 0 2 5 0 11 62 759 0.3474 0 0.0180904522613065 Apoptosis(K)(0.999232)-Apoptosis(R)(0.997423)-Cytokine-cytokine receptor interaction(K)(0.998271)-Natural killer cell mediated cytotoxicity(K)(0.9979182)-TRAIL signaling pathway(N)(0.9990318) 272 ITGB1 10p11.22 0 0 2 0 61 62 1516 0.3474 0 0.0633165829145729 Angiopoietin receptor Tie2-mediated signaling(N)(0.984998)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.988557)-Axon guidance(K)(0.9981808)-Bacterial invasion of epithelial cells(K)(0.9871798)-Cell adhesion molecules (CAMs)(K)(0.9977518)-Cell surface interactions at the vascular wall(R)(0.999046)-Dilated cardiomyopathy(K)(0.989503)-ECM-receptor interaction(K)(0.9912008)-Focal adhesion(K)(0.9973474)-Formation of Platelet plug(R)(0.9971504)-Hypertrophic cardiomyopathy (HCM)(K)(0.9933208)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.993045)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9965012)-Integrin signalling pathway(P)(0.9990014)-Leishmaniasis(K)(0.9956746)-Leukocyte transendothelial migration(K)(0.9961034)-Pathogenic Escherichia coli infection(K)(0.9669852)-Pathways in cancer(K)(0.998897)-Phagosome(K)(0.9989278)-Proteogylcan syndecan-mediated signaling events(N)(0.997678)-Reelin signaling pathway(N)(0.9891288)-Regulation of actin cytoskeleton(K)(0.9988522)-Shigellosis(K)(0.9928318)-Signaling events mediated by PRL(N)(0.99485)-a6b1 and a6b4 Integrin signaling(N)(0.9261006)-agrin in postsynaptic differentiation(B)(0.9889172)-b cell survival pathway(B)(0.9901602)-integrin signaling pathway(B)(0.9830598)-mcalpain and friends in cell motility(B)(0.9699214) 273 GEMIN4 17p13.3 0 0 0 11 430 62 49 0.3474 0 0.44321608040201 Metabolism of non-coding RNA(R)(0.9985012) 274 MYH9 22q12.3 0 0 3 2 272 61 404 0.3474 1 0.278391959798995 Nicotinic acetylcholine receptor signaling pathway(P)(0.9979138)-Regulation of actin cytoskeleton(K)(0.9985122)-Tight junction(K)(0.9986754)-Viral myocarditis(K)(0.9969448) 275 PCSK7 11q23.3 0 0 0 14 361 61 160 0.3474 1 0.376884422110553 Alzheimer disease-amyloid secretase pathway(P)(0.9985358)-Alzheimer disease-presenilin pathway(P)(0.9989612) 276 LSS 21q22.3 0 0 5 0 69 61 1123 0.3474 0 0.0743718592964824 Metabolic pathways(K)(0.9975378)-Steroid biosynthesis(K)(0.994388) 277 TNFRSF13B 17p11.2 0 0 5 6 371 61 573 0.3474 0 0.38391959798995 Cytokine-cytokine receptor interaction(K)(0.999467)-Intestinal immune network for IgA production(K)(0.9976142)-Primary immunodeficiency(K)(0.9986)-Proteogylcan syndecan-mediated signaling events(N)(0.9983266) 278 MNAT1 14q23.1 0 0 5 0 157 60 574 0.3475 0 0.162814070351759 AndrogenReceptor(C)(0.9970046)-DNA Repair(R)(0.995629)-Formation and Maturation of mRNA Transcript(R)(0.9982722)-G1 Phase(R)(0.9871404)-G1/S Transition(R)(0.9926448)-G2/M Transition(R)(0.99872)-HIV Life Cycle(R)(0.9950254)-Nucleotide excision repair(K)(0.9946332)-Retinoic acid receptors-mediated signaling(N)(0.9979638)-S Phase(R)(0.86668)-Transcription(R)(0.9979094)-mRNA Processing(R)(0.9883622) 279 ADRB3 8p12 0 39 36 9 170 60 780 0.3475 0 0.255276381909548 Calcium signaling pathway(K)(0.9985628)-Class A/1 (Rhodopsin-like receptors)(R)(0.997849)-Endocytosis(K)(0.998839)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9931798)-Neuroactive ligand-receptor interaction(K)(0.9994988)-Receptor-ligand complexes bind G proteins(R)(0.9959544)-Salivary secretion(K)(0.9976288) 280 TXNL4A 18q23 0 0 2 1 207 60 232 0.3475 0 0.21105527638191 Formation and Maturation of mRNA Transcript(R)(0.9994124)-Spliceosome(K)(0.995838) 281 TK2 16q21 0 0 0 10 498 59 1235 0.3475 0 0.510552763819095 Drug metabolism - other enzymes(K)(0.9855414)-G1/S Transition(R)(0.9973622)-Metablism of nucleotides(R)(0.996903)-Metabolic pathways(K)(0.9991036)-Pyrimidine metabolism(K)(0.9971964) 282 MTMR7 8p22 0 1 3 28 351 59 1131 0.3475 0 0.384924623115578 Fructose and mannose metabolism(K)(0.995311)-Metabolic pathways(K)(0.9985852)-Riboflavin metabolism(K)(0.9973926) 283 TAF12 1p35.3 0 0 0 3 241 59 254 0.3475 0 0.245226130653266 Basal transcription factors(K)(0.995989)-Formation and Maturation of mRNA Transcript(R)(0.9988612)-HIV Life Cycle(R)(0.996295)-Transcription(R)(0.998969) 284 GABARAPL2 16q23.1 0 0 2 9 498 59 35 0.3475 0 0.511557788944724 Regulation of autophagy(K)(0.9993124) 285 CBL 11q23.3 0 0 2 13 353 58 1480 0.3498 0 0.369849246231156 Bacterial invasion of epithelial cells(K)(0.9909558)-EGFR1(C)(0.9973158)-Endocytosis(K)(0.9985812)-ErbB signaling pathway(K)(0.992082)-Fc-epsilon receptor I signaling in mast cells(N)(0.9915554)-IFN-gamma pathway(N)(0.9973098)-Insulin signaling pathway(K)(0.999035)-Integrins in angiogenesis(N)(0.9973718)-Jak-STAT signaling pathway(K)(0.9988902)-KitReceptor(C)(0.980002)-Nectin adhesion pathway(N)(0.9972146)-Pathways in cancer(K)(0.9989974)-Plasma membrane estrogen receptor signaling(N)(0.990219)-Proteogylcan syndecan-mediated signaling events(N)(0.9972022)-Signaling by EGFR(R)(0.9894372)-Signaling by FGFR(R)(0.9757602)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9869268)-Sphingosine 1-phosphate (S1P) pathway(N)(0.99799)-T cell receptor signaling pathway(K)(0.9970454)-TCR signaling in naive CD4+ T cells(N)(0.9935724)-Ubiquitin mediated proteolysis(K)(0.9983198)-il-2 receptor beta chain in t cell activation(B)(0.9903428) 286 PML 15q24.1 0 2 0 0 147 57 1114 0.3498 1 0.149748743718593 Acute myeloid leukemia(K)(0.9792354)-Endocytosis(K)(0.9970916)-Glypican pathway(N)(0.9965398)-IFN-gamma pathway(N)(0.99817)-Pathways in cancer(K)(0.9987846)-TNF alpha/NF-kB(C)(0.9978256)-Ubiquitin mediated proteolysis(K)(0.998275)-Vitamin D metabolism and pathway(P)(0.9945342)-p53 pathway(P)(0.9942454)-regulation of transcriptional activity by pml(B)(0.9961422) 287 CCL11 17q12 0 0 6 2 191 57 828 0.3498 0 0.2 Asthma(K)(0.996876)-Chemokine signaling pathway(K)(0.9984264)-Cytokine-cytokine receptor interaction(K)(0.9988802)-IFN-gamma pathway(N)(0.9985542)-NOD-like receptor signaling pathway(K)(0.9984218)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.991971)-ccr3 signaling in eosinophils(B)(0.9966364)-chrebp regulation by carbohydrates and camp(B)(0.9954288)-corticosteroids and cardioprotection(B)(0.991752)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9371066)-ion channels and their functional role in vascular endothelium(B)(0.9965974)-ß-arrestins in gpcr desensitization(B)(0.995568) 288 CDH13 16q23.3 0 0 0 11 540 57 299 0.3498 0 0.553768844221106 Wnt signaling pathway(P)(0.9984892) 289 ACAT2 6q25.3 0 0 0 4 212 57 1173 0.3498 0 0.217085427135678 Butanoate metabolism(K)(0.817763)-Fatty acid metabolism(K)(0.99711)-Lysine degradation(K)(0.9982526)-Metabolic pathways(K)(0.9986092)-Pyruvate metabolism(K)(0.9954088)-Terpenoid backbone biosynthesis(K)(0.995562)-Tryptophan metabolism(K)(0.9977522) 290 EIF2S1 14q23.3 0 0 0 1 192 57 448 0.3498 0 0.193969849246231 Apoptosis signaling pathway(P)(0.9969486)-Metabolism of proteins(R)(0.9992382)-Protein processing in endoplasmic reticulum(K)(0.998337)-double stranded rna induced gene expression(B)(0.9946642)-eukaryotic protein translation(B)(0.9927814)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9979064) 291 CALM1 14q32.11 0 0 0 2 169 56 2001 0.3512 0 0.171859296482412 Alzheimer's disease(K)(0.9953084)-BMP receptor signaling(N)(0.9959486)-Calcium signaling pathway(K)(0.9980368)-Endothelins(N)(0.9713536)-Further platelet releasate(R)(0.9869104)-Gastric acid secretion(K)(0.997145)-Glioma(K)(0.966698)-Glypican pathway(N)(0.994927)-GnRH signaling pathway(K)(0.98759)-IFN-gamma pathway(N)(0.997949)-IL1-mediated signaling events(N)(0.9897458)-IL2-mediated signaling events(N)(0.9882948)-Insulin signaling pathway(K)(0.9956404)-Long-term potentiation(K)(0.9617364)-Melanogenesis(K)(0.99767)-Metabolism of carbohydrates(R)(0.9986658)-Metabolism of nitric oxide(R)(0.9686998)-Neurotrophin signaling pathway(K)(0.992516)-Olfactory transduction(K)(0.9984626)-Oocyte meiosis(K)(0.9973566)-Opioid Signalling(R)(0.9906716)-Phosphatidylinositol signaling system(K)(0.9982414)-Phototransduction(K)(0.9684452)-Plasma membrane estrogen receptor signaling(N)(0.9967278)-Salivary secretion(K)(0.9950674)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9960674)-Signalling by NGF(R)(0.9976728)-TCR signaling in naive CD4+ T cells(N)(0.9799978)-TNF receptor signaling pathway(N)(0.9896202)-TRAIL signaling pathway(N)(0.9918578)-VEGF signaling pathway(K)(0.9405588)-Vascular smooth muscle contraction(K)(0.9960532) 292 RASA1 5q14.3 0 0 0 1 159 56 1275 0.3512 0 0.160804020100503 Angiogenesis(P)(0.9917018)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9888978)-Axon guidance(K)(0.9994644)-EGF receptor signaling pathway(P)(0.9947352)-EGFR1(C)(0.9970782)-FGF signaling pathway(P)(0.9909456)-Fc-epsilon receptor I signaling in mast cells(N)(0.9901038)-Glypican pathway(N)(0.9967408)-IL2-mediated signaling events(N)(0.9960368)-Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade(P)(0.9797714)-KitReceptor(C)(0.9942476)-MAPK signaling pathway(K)(0.9992322)-Nectin adhesion pathway(N)(0.9970088)-Plasma membrane estrogen receptor signaling(N)(0.9951144)-Proteogylcan syndecan-mediated signaling events(N)(0.9977924)-Signaling by Aurora kinases(N)(0.9918866)-Signaling by PDGF(R)(0.9986634)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9951998)-Signaling events regulated by Ret tyrosine kinase(N)(0.9948874)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9787112)-TRAIL signaling pathway(N)(0.9951714)-p75(NTR)-mediated signaling(N)(0.9968382)-tpo signaling pathway(B)(0.9613418) 293 ACCN1 17q12 0 6 15 3 216 56 52 0.3512 0 0.241206030150754 Taste transduction(K)(0.9989352) 294 GSTT2 22q11.23 0 0 2 2 244 55 113 0.3513 0 0.249246231155779 Drug metabolism - cytochrome P450(K)(0.995503)-Glutathione metabolism(K)(0.9983832)-Metabolism of xenobiotics by cytochrome P450(K)(0.9977778) 295 PIK3CB 3q22.3 0 1 2 0 65 55 1726 0.3513 0 0.0683417085427136 Aldosterone-regulated sodium reabsorption(K)(0.9935568)-Alpha6Beta4Integrin(C)(0.9908764)-Amoebiasis(K)(0.996082)-Apoptosis signaling pathway(P)(0.9869466)-Apoptosis(K)(0.9931768)-B cell receptor signaling pathway(K)(0.9876098)-Bacterial invasion of epithelial cells(K)(0.9822596)-Cell surface interactions at the vascular wall(R)(0.997908)-Chagas disease(K)(0.9943404)-Chemokine signaling pathway(K)(0.9974786)-EGF receptor signaling pathway(P)(0.9373958)-EGFR1(C)(0.9973586)-Endothelin signaling pathway(P)(0.9663334)-ErbB signaling pathway(K)(0.9712454)-FGF signaling pathway(P)(0.9617398)-Fc gamma R-mediated phagocytosis(K)(0.995358)-Focal adhesion(K)(0.9927388)-Hypoxia response via HIF activation(P)(0.9553608)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9777368)-Inositol phosphate metabolism(K)(0.9857184)-Insulin signaling pathway(K)(0.9988212)-Integrin signalling pathway(P)(0.9936302)-Jak-STAT signaling pathway(K)(0.998661)-LPA receptor mediated events(N)(0.9927402)-Leukocyte transendothelial migration(K)(0.99741)-Natural killer cell mediated cytotoxicity(K)(0.992432)-Neurotrophin signaling pathway(K)(0.9964524)-PI3 kinase pathway(P)(0.9149)-Pathways in cancer(K)(0.9973456)-Phosphatidylinositol signaling system(K)(0.993539)-Progesterone-mediated oocyte maturation(K)(0.996193)-Prostate cancer(K)(0.9711074)-Regulation of actin cytoskeleton(K)(0.9988064)-Signaling by Insulin receptor(R)(0.9532604)-Signaling by PDGF(R)(0.9418784)-Signalling by NGF(R)(0.9971946)-T cell receptor signaling pathway(K)(0.9825966)-TCR signaling(R)(0.9781488)-Toll-like receptor signaling pathway(K)(0.996407)-Type II diabetes mellitus(K)(0.9934486)-VEGF signaling pathway(K)(0.9208532)-mTOR signaling pathway(K)(0.9888086) 296 SEC63 6q21 0 3 8 6 234 55 184 0.3513 0 0.252261306532663 Protein export(K)(0.996749)-Protein processing in endoplasmic reticulum(K)(0.9987834) 297 ACOT4 14q24.3 0 0 0 2 200 55 21 0.3513 0 0.203015075376884 Biosynthesis of unsaturated fatty acids(K)(0.9988094) 298 ADRBK2 22q11.23 0 1 1 0 264 54 946 0.3536 0 0.267336683417085 Chemokine signaling pathway(K)(0.9984594)-Endocytosis(K)(0.9983958)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9985508)-Olfactory transduction(K)(0.9992336)-Parkinson disease(P)(0.997071)-Thromboxane A2 receptor signaling(N)(0.995196) 299 CSGALNACT1 8p21.3 0 1 3 29 362 54 1129 0.3536 0 0.396984924623116 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.997865)-Metabolic pathways(K)(0.9986636) 300 FUCA1 1p36.11 0 0 0 3 254 53 128 0.3536 0 0.258291457286432 Lysosome(K)(0.9989842)-Other glycan degradation(K)(0.9977854) 301 ADCY3 2p23.3 0 0 2 3 87 52 1621 0.3536 0 0.0924623115577889 Calcium signaling pathway(K)(0.9985422)-Chemokine signaling pathway(K)(0.999127)-Dilated cardiomyopathy(K)(0.9921666)-Endothelin signaling pathway(P)(0.8999366)-Endothelins(N)(0.993897)-Gap junction(K)(0.9948646)-Gastric acid secretion(K)(0.9889764)-GnRH signaling pathway(K)(0.983829)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9940534)-LPA receptor mediated events(N)(0.9978278)-Melanogenesis(K)(0.9976782)-Olfactory transduction(K)(0.9990108)-Oocyte meiosis(K)(0.999152)-Opioid Signalling(R)(0.9856372)-Pancreatic secretion(K)(0.996194)-Progesterone-mediated oocyte maturation(K)(0.9799852)-Purine metabolism(K)(0.9987642)-Salivary secretion(K)(0.9919638)-Signalling by NGF(R)(0.998121)-Vascular smooth muscle contraction(K)(0.994733)-Vasopressin-regulated water reabsorption(K)(0.9967396)-Vibrio cholerae infection(K)(0.9976526) 302 PIGN 18q21.33 0 0 3 1 204 52 1123 0.3536 0 0.209045226130653 Metabolic pathways(K)(0.997199) 303 FZD3 8p21.1 0 0 3 31 354 52 1176 0.3536 0 0.389949748743719 Alzheimer disease-presenilin pathway(P)(0.9969482)-Angiogenesis(P)(0.9933402)-Glypican pathway(N)(0.99893)-Melanogenesis(K)(0.996036)-Pathways in cancer(K)(0.998359)-Proteogylcan syndecan-mediated signaling events(N)(0.9989108)-Wnt signaling pathway(K)(0.9965498)-Wnt signaling pathway(P)(0.9967874) 304 MYC 8q24.21 0 10 61 0 10 52 1649 0.3536 1 0.0814070351758794 Cell cycle(K)(0.9982124)-EGFR1(C)(0.9979912)-ErbB signaling pathway(K)(0.9954098)-FOXM1 transcription factor network(N)(0.9934008)-Glypican pathway(N)(0.9958426)-IFN-gamma pathway(N)(0.9865982)-IL2-mediated signaling events(N)(0.9771998)-IL6-mediated signaling events(N)(0.99352)-Jak-STAT signaling pathway(K)(0.9963776)-MAPK signaling pathway(K)(0.9981158)-Nectin adhesion pathway(N)(0.997265)-Pathways in cancer(K)(0.9987254)-Presenilin action in Notch and Wnt signaling(N)(0.995356)-Regulation of Telomerase(N)(0.9960812)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9959326)-TGF-beta signaling pathway(K)(0.996995)-TGFBR(C)(0.9984722)-TNF receptor signaling pathway(N)(0.9966572)-TRAIL signaling pathway(N)(0.9931628)-Wnt signaling pathway(K)(0.9976906)-Wnt signaling pathway(P)(0.9982354)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9972658)-p38 mapk signaling pathway(B)(0.9889882)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.984057)-telomeres telomerase cellular aging and immortality(B)(0.9806172)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9886012) 305 CFD 19p13.3 0 0 3 1 207 52 252 0.3536 0 0.212060301507538 Complement and coagulation cascades(K)(0.9981906)-Formation of Platelet plug(R)(0.998294)-Innate Immunity Signaling(R)(0.997266) 306 NARS2 11q14.1 0 24 33 4 144 52 41 0.3536 0 0.206030150753769 Aminoacyl-tRNA biosynthesis(K)(0.9989322) 307 CYP17A1 10q24.32 0 0 4 1 162 52 1211 0.3536 0 0.167839195979899 Biological oxidations(R)(0.997615)-Metabolic pathways(K)(0.9984898)-Metabolism of lipids and lipoproteins(R)(0.9983556)-Steroid hormone biosynthesis(K)(0.997797) 308 TPO 2p25.3 0 0 4 0 93 52 1534 0.3536 0 0.0974874371859296 Autoimmune thyroid disease(K)(0.996201)-Cytokine-cytokine receptor interaction(K)(0.9983918)-Hematopoietic cell lineage(K)(0.998642)-Jak-STAT signaling pathway(K)(0.9972758)-Metabolic pathways(K)(0.997783)-Tyrosine metabolism(K)(0.995119) 309 NFATC1 18q23 0 0 3 2 222 51 1323 0.3565 0 0.228140703517588 Axon guidance(K)(0.9983622)-B cell receptor signaling pathway(K)(0.9886664)-BMP receptor signaling(N)(0.997341)-Endothelins(N)(0.998146)-Glypican pathway(N)(0.9984744)-IFN-gamma pathway(N)(0.9981118)-IL1-mediated signaling events(N)(0.9961858)-Natural killer cell mediated cytotoxicity(K)(0.9985192)-Plasma membrane estrogen receptor signaling(N)(0.9987364)-T cell receptor signaling pathway(K)(0.9953822)-TCR signaling in naive CD4+ T cells(N)(0.9935442)-TNF receptor signaling pathway(N)(0.9967736)-TRAIL signaling pathway(N)(0.9612052)-VEGF signaling pathway(K)(0.994772)-Wnt signaling pathway(K)(0.998456)-Wnt signaling pathway(P)(0.9983864)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9849814)-effects of calcineurin in keratinocyte differentiation(B)(0.9806016)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9095732)-gata3 participate in activating the th2 cytokine genes expression(B)(0.9729112)-nfat and hypertrophy of the heart (B)(0.9964634)-t cell receptor signaling pathway(B)(0.9795384) 310 MAP3K4 6q26 0 0 0 4 210 51 1023 0.3565 0 0.215075376884422 BMP receptor signaling(N)(0.9979928)-EGF receptor signaling pathway(P)(0.9950022)-EGFR1(C)(0.9987216)-FGF signaling pathway(P)(0.9924014)-Glypican pathway(N)(0.994267)-GnRH signaling pathway(K)(0.9972956)-IFN-gamma pathway(N)(0.994509)-Integrin signalling pathway(P)(0.9973678)-MAPK signaling pathway(K)(0.9991258)-Oxidative stress response(P)(0.986709)-Wnt(C)(0.998064)-mapkinase signaling pathway(B)(0.9912504) 311 DIS3 13q22.1 0 0 0 8 273 50 59 0.36 0 0.282412060301508 RNA degradation(K)(0.9984564) 312 DLAT 11q23.1 0 0 0 14 364 49 1233 0.36 0 0.379899497487437 Glucose Regulation of Insulin Secretion(R)(0.9980776)-Metabolic pathways(K)(0.9977502)-Metabolism of carbohydrates(R)(0.9995008)-Pyruvate metabolism(K)(0.9971198)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9965674) 313 FOXF1 16q24.1 0 0 1 10 490 49 75 0.36 0 0.503517587939698 FOXA transcription factor networks(N)(0.9958772) 314 EEF1A1 6q13 0 0 0 6 244 49 201 0.36 0 0.251256281407035 Metabolism of proteins(R)(0.9982462) 315 OR52W1 11p15.4 0 0 0 1 148 49 389 0.36 0 0.149748743718593 Olfactory transduction(K)(0.9987276) 316 GRIK2 6q16.3 0 0 5 2 253 49 395 0.36 0 0.261306532663317 Huntington disease(P)(0.9975578)-Neuroactive ligand-receptor interaction(K)(0.9995216) 317 SOS2 14q22.1 0 0 11 0 115 48 1506 0.36 0 0.126633165829146 B cell receptor signaling pathway(K)(0.991963)-Chemokine signaling pathway(K)(0.997987)-Dorso-ventral axis formation(K)(0.9935784)-EGF receptor signaling pathway(P)(0.920396)-EGFR1(C)(0.9989456)-ErbB signaling pathway(K)(0.986993)-FGF signaling pathway(P)(0.9909014)-Focal adhesion(K)(0.9986862)-Gap junction(K)(0.9960974)-GnRH signaling pathway(K)(0.9963742)-Insulin signaling pathway(K)(0.9986484)-Integrin signalling pathway(P)(0.9975014)-Jak-STAT signaling pathway(K)(0.999018)-MAPK signaling pathway(K)(0.9982972)-Natural killer cell mediated cytotoxicity(K)(0.998336)-Neurotrophin signaling pathway(K)(0.9940738)-Pathways in cancer(K)(0.9984972)-Prostate cancer(K)(0.9872188)-Regulation of actin cytoskeleton(K)(0.998862)-Signaling by Rho GTPases(R)(0.9989134)-T cell receptor signaling pathway(K)(0.9944716)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.9304022) 318 HNF1B 17q12 0 4 15 2 195 48 34 0.36 0 0.217085427135678 Maturity onset diabetes of the young(K)(0.9961694)-Regulation of beta-cell development(R)(0.9987636) 319 ACSL1 4q35.1 0 0 0 3 140 48 1263 0.36 0 0.143718592964824 Activated AMPK stimulates fatty-acid oxidation in muscle(R)(0.9957056)-Adipocytokine signaling pathway(K)(0.9994672)-Metabolic pathways(K)(0.998083)-PPAR signaling pathway(K)(0.9984798)-Peroxisome(K)(0.9992454) 320 CEP164 11q23.3 0 0 1 14 372 48 83 0.36 0 0.38894472361809 G2/M Transition(R)(0.9990236) 321 SNRPB 20p13 0 0 2 1 62 48 502 0.36 0 0.0653266331658292 Formation and Maturation of mRNA Transcript(R)(0.9980734)-Influenza Life Cycle(R)(0.9974464)-Metabolism of non-coding RNA(R)(0.9965644)-Spliceosome(K)(0.9985478)-Systemic lupus erythematosus(K)(0.9984456) 322 NRXN3 14q24.3 0 0 0 4 194 48 135 0.36 0 0.198994974874372 Cell adhesion molecules (CAMs)(K)(0.9980254) 323 XRCC6 22q13.2 0 0 1 2 293 47 421 0.3625 0 0.29748743718593 Androgen-mediated signaling(N)(0.9716912)-BARD1 signaling events(N)(0.997644)-DNA Repair(R)(0.997799)-HIV Life Cycle(R)(0.9982866)-Non-homologous end-joining(K)(0.9984612)-Regulation of Telomerase(N)(0.998473)-Signaling events mediated by HDAC Class I(N)(0.9986542)-telomeres telomerase cellular aging and immortality(B)(0.9973708) 324 RIMS1 6q13 0 0 1 2 221 47 47 0.3625 0 0.225125628140704 Synaptic Transmission(R)(0.9972992)-Synaptic_vesicle_trafficking(P)(0.947958) 325 MAPK11 22q13.33 0 1 5 2 267 46 1514 0.3625 0 0.276381909547739 Alzheimer disease-amyloid secretase pathway(P)(0.9946102)-Amyotrophic lateral sclerosis (ALS)(K)(0.9961958)-BMP receptor signaling(N)(0.992024)-Chagas disease(K)(0.9934154)-EGF receptor signaling pathway(P)(0.987628)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.995811)-FGF signaling pathway(P)(0.9744854)-Fc epsilon RI signaling pathway(K)(0.9493396)-Glypican pathway(N)(0.9859434)-GnRH signaling pathway(K)(0.9769118)-IFN-gamma pathway(N)(0.99369)-IL1-mediated signaling events(N)(0.971123)-IL2-mediated signaling events(N)(0.9891758)-IL6-mediated signaling events(N)(0.9921494)-Leishmaniasis(K)(0.9859734)-Leukocyte transendothelial migration(K)(0.998132)-MAPK signaling pathway(K)(0.9982506)-NOD-like receptor signaling pathway(K)(0.9956004)-Neurotrophin signaling pathway(K)(0.9940268)-Oxidative stress response(P)(0.9694464)-Plasma membrane estrogen receptor signaling(N)(0.9980146)-Progesterone-mediated oocyte maturation(K)(0.9972466)-RIG-I-like receptor signaling pathway(K)(0.995704)-Regulation of retinoblastoma protein(N)(0.9931976)-Shigellosis(K)(0.9971466)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9920644)-Signalling by NGF(R)(0.9982078)-T cell receptor signaling pathway(K)(0.9921128)-TGF-beta signaling pathway(P)(0.9980268)-TNF receptor signaling pathway(N)(0.9962826)-Thromboxane A2 receptor signaling(N)(0.9924458)-Toll-like receptor signaling pathway(K)(0.998104)-VEGFR3 signaling in lymphatic endothelium(N)(0.9793352)-mapkinase signaling pathway(B)(0.9595766)-p53 pathway feedback loops 2(P)(0.9599754) 326 IKBKG 23q28 0 0 7 7 141 46 1642 0.3625 0 0.155778894472362 Acute myeloid leukemia(K)(0.9700682)-Adipocytokine signaling pathway(K)(0.9968984)-Apoptosis(K)(0.9942606)-B cell receptor signaling pathway(K)(0.9875668)-Chagas disease(K)(0.997586)-Chemokine signaling pathway(K)(0.9975568)-Cytosolic DNA-sensing pathway(K)(0.996231)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9978112)-Fc-epsilon receptor I signaling in mast cells(N)(0.99144)-Glypican pathway(N)(0.9984214)-IL12-mediated signaling events(N)(0.9954038)-IL2-mediated signaling events(N)(0.9933712)-IL23-mediated signaling events(N)(0.9902244)-LPA receptor mediated events(N)(0.992698)-MAPK signaling pathway(K)(0.999276)-NOD-like receptor signaling pathway(K)(0.9942292)-Pathways in cancer(K)(0.9971852)-Primary immunodeficiency(K)(0.9958408)-Prostate cancer(K)(0.9953266)-RIG-I-like receptor signaling pathway(K)(0.9967346)-Shigellosis(K)(0.9962396)-Signaling by Aurora kinases(N)(0.9776772)-Signaling events regulated by Ret tyrosine kinase(N)(0.9934246)-T cell receptor signaling pathway(K)(0.9894666)-TCR signaling in naive CD4+ T cells(N)(0.9907578)-TNF alpha/NF-kB(C)(0.9972594)-TNF receptor signaling pathway(N)(0.9898958)-Toll-like receptor signaling pathway(K)(0.9943778)-bone remodeling(B)(0.898349)-double stranded rna induced gene expression(B)(0.9813272)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9838838)-keratinocyte differentiation(B)(0.9764592)-lectin induced complement pathway(B)(0.9827338)-p75(NTR)-mediated signaling(N)(0.9984858)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9784074)-trefoil factors initiate mucosal healing(B)(0.9668512) 327 SMARCE1 17q21.2 0 5 24 3 188 46 440 0.3625 0 0.221105527638191 Androgen-mediated signaling(N)(0.9891506)-Wnt signaling pathway(P)(0.9986862)-control of gene expression by vitamin d receptor(B)(0.9980856)-the information processing pathway at the ifn beta enhancer(B)(0.997535) 328 SRP54 14q13.2 0 0 3 4 132 46 56 0.3625 0 0.139698492462312 Insulin Synthesis and Secretion(R)(0.9990596)-Protein export(K)(0.9971516) 329 ABR 17p13.3 0 0 1 10 418 46 125 0.3625 0 0.431155778894472 Signaling by Rho GTPases(R)(0.9985284) 330 GNG2 14q22.1 0 0 14 0 102 45 1401 0.3625 0 0.116582914572864 Androgen-mediated signaling(N)(0.967175)-Beta1 adrenergic receptor signaling pathway(P)(0.8192064)-Chemokine signaling pathway(K)(0.9968872)-Formation of Platelet plug(R)(0.997571)-Glypican pathway(N)(0.997914)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.996659)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9961844)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.993936)-LPA receptor mediated events(N)(0.9962322)-Opioid Signalling(R)(0.993547)-Plasma membrane estrogen receptor signaling(N)(0.9935686)-Proteogylcan syndecan-mediated signaling events(N)(0.9983696)-Receptor-ligand complexes bind G proteins(R)(0.9983186)-Signaling events mediated by HDAC Class I(N)(0.9972088)-Signaling events mediated by the Hedgehog family(N)(0.9972952)-Thromboxane A2 receptor signaling(N)(0.9930916)-Wnt signaling pathway(P)(0.998324) 331 TERF2 16q22.1 0 0 0 13 502 45 107 0.3625 0 0.517587939698492 Regulation of Telomerase(N)(0.9987886)-Telomere Maintenance(R)(0.9986306) 332 PMVK 1q21.3 0 0 26 0 6 45 1170 0.3625 0 0.0321608040201005 Metabolic pathways(K)(0.9976388)-Peroxisome(K)(0.9993774)-Terpenoid backbone biosynthesis(K)(0.996322) 333 OR10A7 12q13.2 0 0 1 0 62 45 413 0.3625 0 0.0633165829145729 Olfactory transduction(K)(0.9987426) 334 AP3B1 5q14.1 0 0 0 1 156 45 121 0.3625 0 0.157788944723618 Lysosome(K)(0.998886) 335 TNFRSF10B 8p21.3 0 0 1 33 368 44 818 0.3625 0 0.404020100502513 Apoptosis signaling pathway(P)(0.9940582)-Apoptosis(K)(0.997987)-Apoptosis(R)(0.9987742)-Cytokine-cytokine receptor interaction(K)(0.9993152)-Natural killer cell mediated cytotoxicity(K)(0.998532)-TRAIL signaling pathway(N)(0.9970614)-p53 pathway(P)(0.9964628)-p53 signaling pathway(K)(0.9993132) 336 SNAP29 22q11.21 0 0 3 1 265 44 83 0.3625 0 0.27035175879397 5HT2 type receptor mediated signaling pathway(P)(0.9850912)-Cortocotropin releasing factor receptor signaling pathway(P)(0.993799)-Metabotropic glutamate receptor group III pathway(P)(0.998266)-PNAT(P)(0.9979992)-SNARE interactions in vesicular transport(K)(0.9988366) 337 CYB5R3 22q13.2 0 0 1 2 295 44 57 0.3625 0 0.299497487437186 Amino sugar and nucleotide sugar metabolism(K)(0.9982856)-Metabolism of vitamins and cofactors(R)(0.9986848) 338 ID3 1p36.12 0 0 1 3 244 44 106 0.3625 0 0.249246231155779 ID(C)(0.9964438)-TGF-beta signaling pathway(K)(0.99884) 339 RPA4 23q21.33 0 0 1 9 182 44 172 0.3625 0 0.192964824120603 DNA Replication(R)(0.9939608)-DNA replication(K)(0.991737)-G1/S Transition(R)(0.9972482)-Homologous recombination(K)(0.9971388)-Mismatch repair(K)(0.9944556)-Nucleotide excision repair(K)(0.997757) 340 WHSC1L1 8p12 0 45 39 10 158 44 44 0.3625 1 0.253266331658291 Lysine degradation(K)(0.997367) 341 OR7A10 19p13.12 0 0 5 1 114 44 389 0.3625 0 0.120603015075377 Olfactory transduction(K)(0.9982578) 342 SLC7A5 16q24.2 0 0 1 13 485 43 193 0.3655 0 0.501507537688442 Cell surface interactions at the vascular wall(R)(0.997812)-Metabolism of amino acids(R)(0.9992294)-Transmembrane transport of small molecules(R)(0.9990638) 343 NLN 5q12.3 0 0 1 2 146 43 17 0.3655 0 0.149748743718593 Renin-angiotensin system(K)(0.998915) 344 PIAS3 1q21.1 0 0 19 2 8 43 1120 0.3655 0 0.0291457286432161 Androgen-mediated signaling(N)(0.9605284)-AndrogenReceptor(C)(0.9983142)-Glypican pathway(N)(0.996853)-IFN-gamma pathway(N)(0.9974724)-IL6-mediated signaling events(N)(0.9972996)-Jak-STAT signaling pathway(K)(0.9977238)-Pathways in cancer(K)(0.9983878)-TNF alpha/NF-kB(C)(0.9988474)-Ubiquitin mediated proteolysis(K)(0.998641) 345 CTH 1p31.1 0 0 1 2 162 42 1148 0.3676 0 0.165829145728643 Glycine, serine and threonine metabolism(K)(0.9983636)-Metabolic pathways(K)(0.9988716)-Nitrogen metabolism(K)(0.9978904)-Selenoamino acid metabolism(K)(0.9973972) 346 FUT8 14q23.3 0 1 1 1 183 42 1128 0.3676 0 0.186934673366834 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.998421)-Metabolic pathways(K)(0.9990292)-N-Glycan biosynthesis(K)(0.9983978) 347 IL4 5q31.1 0 0 0 1 120 42 1175 0.3676 0 0.121608040201005 Asthma(K)(0.9889274)-BMP receptor signaling(N)(0.995401)-Cytokine-cytokine receptor interaction(K)(0.9986328)-Endothelins(N)(0.9972778)-Fc epsilon RI signaling pathway(K)(0.996483)-Glypican pathway(N)(0.99869)-Hematopoietic cell lineage(K)(0.9965488)-IFN-gamma pathway(N)(0.9958476)-IL1-mediated signaling events(N)(0.9951136)-IL12-mediated signaling events(N)(0.9964928)-IL2-mediated signaling events(N)(0.996909)-Intestinal immune network for IgA production(K)(0.988231)-Jak-STAT signaling pathway(K)(0.9974912)-Leishmaniasis(K)(0.9942778)-Plasma membrane estrogen receptor signaling(N)(0.9967156)-T cell receptor signaling pathway(K)(0.9943034)-TCR signaling in naive CD4+ T cells(N)(0.9978032)-TNF receptor signaling pathway(N)(0.9940816)-TRAIL signaling pathway(N)(0.9751594) 348 SLC25A17 22q13.2 0 0 0 2 298 42 169 0.3676 0 0.301507537688442 Metabolism of lipids and lipoproteins(R)(0.999736)-Peroxisome(K)(0.9980666) 349 GNG3 11q12.3 0 0 4 2 125 41 804 0.3723 0 0.131658291457286 Beta1 adrenergic receptor signaling pathway(P)(0.9037784)-Chemokine signaling pathway(K)(0.9987312)-Formation of Platelet plug(R)(0.9981898)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9982486)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.996693)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.9907002)-Opioid Signalling(R)(0.9975688)-Receptor-ligand complexes bind G proteins(R)(0.9957746)-Taste transduction(K)(0.9968338)-Wnt signaling pathway(P)(0.9991738) 350 GNGT2 17q21.32 0 11 24 1 119 41 526 0.3723 0 0.155778894472362 Beta1 adrenergic receptor signaling pathway(P)(0.8968378)-Chemokine signaling pathway(K)(0.9984238)-Formation of Platelet plug(R)(0.9983994)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9980028)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9981736)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.9148108)-Opioid Signalling(R)(0.9989982)-Receptor-ligand complexes bind G proteins(R)(0.999061)-Visual signal transduction: Cones(N)(0.9976016)-visual signal transduction(B)(0.9961448) 351 POMT2 14q24.3 0 0 3 1 175 40 3 0.375 0 0.179899497487437 O-Mannosyl glycan biosynthesis(K)(0.9978168) 352 SPIRE2 16q24.3 0 0 1 13 466 40 25 0.375 0 0.482412060301508 Dorso-ventral axis formation(K)(0.998348) 353 PSMA3 14q23.1 0 0 3 0 152 40 512 0.375 0 0.155778894472362 APC/C-mediated degradation of cell cycle proteins(R)(0.9925854)-Apoptosis(R)(0.9973404)-Cell Cycle Checkpoints(R)(0.9964764)-G1/S Transition(R)(0.9952728)-Host Interactions of HIV factors(R)(0.9982932)-Metabolism of amino acids(R)(0.9977262)-Parkinson disease(P)(0.997856)-Proteasome(K)(0.9259154)-S Phase(R)(0.991917)-Signaling by Aurora kinases(N)(0.9737746)-Signaling by Wnt(R)(0.997616) 354 PPP2R1B 11q23.1 0 0 0 15 361 40 787 0.375 0 0.377889447236181 Chagas disease(K)(0.9980662)-Long-term depression(K)(0.9981376)-M Phase(R)(0.9989734)-Oocyte meiosis(K)(0.99866)-Opioid Signalling(R)(0.9932648)-Signaling by Wnt(R)(0.9924838)-Signalling by NGF(R)(0.9994476)-TGF-beta signaling pathway(K)(0.9966412)-Tight junction(K)(0.998119)-Wnt signaling pathway(K)(0.9988708) 355 CALML5 10p15.1 0 0 12 0 65 39 1205 0.375 0 0.0773869346733668 Alzheimer's disease(K)(0.9976174)-Calcium signaling pathway(K)(0.9981418)-Gastric acid secretion(K)(0.9942172)-Glioma(K)(0.9938322)-GnRH signaling pathway(K)(0.9951654)-Insulin signaling pathway(K)(0.9982252)-Long-term potentiation(K)(0.9892636)-Melanogenesis(K)(0.9977576)-Neurotrophin signaling pathway(K)(0.9958548)-Olfactory transduction(K)(0.9974482)-Oocyte meiosis(K)(0.998281)-Phosphatidylinositol signaling system(K)(0.9961958)-Phototransduction(K)(0.9928968)-Salivary secretion(K)(0.9927908)-Vascular smooth muscle contraction(K)(0.9968374) 356 NAT1 8p22 0 1 4 26 345 39 1143 0.375 0 0.377889447236181 Biological oxidations(R)(0.9989914)-Drug metabolism - other enzymes(K)(0.9734472)-Metabolic pathways(K)(0.9987266) 357 FDX1 11q22.3 0 0 0 10 357 39 13 0.375 0 0.368844221105528 Vitamin D metabolism and pathway(P)(0.9980866) 358 POLE3 9q32 0 0 1 1 151 39 1256 0.375 0 0.153768844221106 Base excision repair(K)(0.9987952)-DNA replication(K)(0.998373)-Metabolic pathways(K)(0.999175)-Nucleotide excision repair(K)(0.9975072)-Purine metabolism(K)(0.9981244)-Pyrimidine metabolism(K)(0.9964024) 359 DIAPH2 23q21.33 0 0 2 12 206 39 215 0.375 0 0.221105527638191 Regulation of actin cytoskeleton(K)(0.9991404) 360 ABCD3 1p21.3 0 0 2 2 163 39 131 0.375 0 0.167839195979899 ABC transporters(K)(0.998607)-Peroxisome(K)(0.9983706)-Transmembrane transport of small molecules(R)(0.99452) 361 PIK3C3 18q12.3 0 0 1 3 178 39 1759 0.375 0 0.182914572864322 EGF receptor signaling pathway(P)(0.9971666)-Endothelin signaling pathway(P)(0.997126)-FGF signaling pathway(P)(0.9961694)-Hypoxia response via HIF activation(P)(0.9955532)-Innate Immunity Signaling(R)(0.9951498)-Inositol phosphate metabolism(K)(0.9952228)-Integrin signalling pathway(P)(0.998598)-Metabolic pathways(K)(0.9992404)-Phagosome(K)(0.9983324)-Phosphatidylinositol signaling system(K)(0.9953302)-Ras Pathway(P)(0.997147)-Regulation of autophagy(K)(0.9981734)-T cell activation(P)(0.9963792) 362 DMD 23p21.1 0 0 1 7 183 38 232 0.379 0 0.191959798994975 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9965982)-Dilated cardiomyopathy(K)(0.9971292)-Hypertrophic cardiomyopathy (HCM)(K)(0.9959642)-Muscle contraction(R)(0.995958)-Viral myocarditis(K)(0.9989254)-agrin in postsynaptic differentiation(B)(0.9984482) 363 LSM7 19p13.3 0 0 2 1 163 38 180 0.379 0 0.166834170854271 RNA degradation(K)(0.9977344)-Spliceosome(K)(0.9981286) 364 ITPR2 12p11.23 0 3 5 1 64 38 1144 0.379 0 0.0733668341708543 Alzheimer's disease(K)(0.997915)-B cell activation(P)(0.9886922)-Calcium signaling pathway(K)(0.9980158)-Endothelin signaling pathway(P)(0.9766556)-Gap junction(K)(0.9939166)-Gastric acid secretion(K)(0.9938704)-GnRH signaling pathway(K)(0.9952842)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9992456)-Long-term depression(K)(0.9938038)-Long-term potentiation(K)(0.9684038)-Oocyte meiosis(K)(0.9977468)-Opioid Signalling(R)(0.9920702)-Pancreatic secretion(K)(0.9970312)-Phosphatidylinositol signaling system(K)(0.9965802)-Salivary secretion(K)(0.9941038)-Signalling by NGF(R)(0.998492)-Vascular smooth muscle contraction(K)(0.9971732)-Wnt signaling pathway(P)(0.998229) 365 PI4KA 22q11.21 0 0 4 1 281 37 1223 0.3833 0 0.287437185929648 Inositol phosphate metabolism(K)(0.9944232)-Integrins in angiogenesis(N)(0.9988064)-Metabolic pathways(K)(0.9990702)-Phosphatidylinositol signaling system(K)(0.9980332)-cell cycle: g2/m checkpoint(B)(0.9968776) 366 CASP1 11q22.3 0 0 1 9 332 37 678 0.3833 0 0.343718592964824 Amyotrophic lateral sclerosis (ALS)(K)(0.9984128)-Cellular roles of Anthrax toxin(N)(0.9958472)-Cytosolic DNA-sensing pathway(K)(0.9984642)-IFN-gamma pathway(N)(0.9954648)-IL1-mediated signaling events(N)(0.9974298)-NOD-like receptor signaling pathway(K)(0.9972578)-TNF receptor signaling pathway(N)(0.99754)-TRAIL signaling pathway(N)(0.9983934)-internal ribosome entry pathway(B)(0.9946902) 367 ARAP2 4p14 0 0 0 4 157 37 390 0.3833 0 0.161809045226131 Endocytosis(K)(0.9995972)-Signaling by Rho GTPases(R)(0.9986466)-adp-ribosylation factor(B)(0.9961166)-rac1 cell motility signaling pathway(B)(0.9969418)-rho cell motility signaling pathway(B)(0.9960542)-t cell receptor signaling pathway(B)(0.9972814) 368 POLR2K 8q22.2 0 3 64 0 7 36 1635 0.3864 0 0.0743718592964824 DNA Repair(R)(0.996251)-Formation and Maturation of mRNA Transcript(R)(0.9977034)-HIV Life Cycle(R)(0.998226)-Huntington's disease(K)(0.9971158)-Influenza Life Cycle(R)(0.99772)-Metabolic pathways(K)(0.9988188)-Purine metabolism(K)(0.99763)-Pyrimidine metabolism(K)(0.9949622)-Regulatory RNA pathways(R)(0.9943968)-Transcription(R)(0.9978142)-mRNA Processing(R)(0.9945622) 369 ACOX1 17q25.1 0 3 19 0 84 36 1295 0.3864 0 0.106532663316583 Biosynthesis of unsaturated fatty acids(K)(0.9919476)-Metabolic pathways(K)(0.9979546)-Metabolism of lipids and lipoproteins(R)(0.9986294)-PPAR signaling pathway(K)(0.9974688)-Peroxisome(K)(0.996835)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9956362) 370 THOC2 23q25 0 0 2 9 201 36 128 0.3864 0 0.213065326633166 Spliceosome(K)(0.9991874) 371 UGT1A8 2q37.1 0 0 0 0 111 35 1192 0.3864 0 0.111557788944724 Drug metabolism - cytochrome P450(K)(0.9978784)-Drug metabolism - other enzymes(K)(0.9910608)-Metabolic pathways(K)(0.9987812)-Metabolism of xenobiotics by cytochrome P450(K)(0.9952772)-Porphyrin and chlorophyll metabolism(K)(0.9981192)-Retinol metabolism(K)(0.9979598)-Starch and sucrose metabolism(K)(0.997666)-Steroid hormone biosynthesis(K)(0.9977052) 372 XPO1 2p15 0 0 1 2 87 35 1339 0.3864 1 0.0904522613065327 FoxO family signaling(N)(0.9929516)-G2/M Transition(R)(0.9988084)-Glypican pathway(N)(0.9969068)-HIV Life Cycle(R)(0.997764)-Host Interactions of HIV factors(R)(0.9979284)-IL1-mediated signaling events(N)(0.9937336)-IL12-mediated signaling events(N)(0.9976872)-IL2-mediated signaling events(N)(0.9944902)-IL23-mediated signaling events(N)(0.9831224)-Influenza Life Cycle(R)(0.9984394)-LPA receptor mediated events(N)(0.9960242)-M Phase(R)(0.9969506)-Signaling by Aurora kinases(N)(0.9677186)-Signaling events mediated by HDAC Class I(N)(0.9976788)-Signaling events regulated by Ret tyrosine kinase(N)(0.9915012)-TCR signaling in naive CD4+ T cells(N)(0.9971642)-TNF receptor signaling pathway(N)(0.9957628)-TRAIL signaling pathway(N)(0.988136)-p75(NTR)-mediated signaling(N)(0.9977)-regulation of spermatogenesis by crem(B)(0.9753382) 373 RAF1 3p25.1 0 0 2 0 99 35 2064 0.3864 1 0.101507537688442 () 374 TRADD 16q22.1 0 0 1 11 485 35 721 0.3864 0 0.499497487437186 Adipocytokine signaling pathway(K)(0.9972492)-Apoptosis(K)(0.9973038)-Apoptosis(R)(0.9958856)-RIG-I-like receptor signaling pathway(K)(0.9974162)-Sphingosine 1-phosphate (S1P) pathway(N)(0.999529)-TNF alpha/NF-kB(C)(0.9989538)-TNF receptor signaling pathway(N)(0.9961968)-TRAIL signaling pathway(N)(0.9926404)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9884818) 375 GTF2F2 13q14.12 0 0 0 12 312 35 414 0.3864 0 0.325628140703518 AndrogenReceptor(C)(0.9987298)-Basal transcription factors(K)(0.9971206)-Formation and Maturation of mRNA Transcript(R)(0.9985482)-HIV Life Cycle(R)(0.9968788)-Influenza Life Cycle(R)(0.9986048)-Transcription(R)(0.9978986)-mRNA Processing(R)(0.9795564) 376 B3GAT2 6q13 0 0 2 1 196 35 1139 0.3864 0 0.2 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9977116)-Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9974012)-Metabolic pathways(K)(0.9984732) 377 PPP1R1B 17q12 0 79 32 2 140 35 89 0.3864 0 0.25427135678392 Opioid Signalling(R)(0.9986808)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9984844) 378 OR1D4 17p13.3 0 0 1 3 419 35 389 0.3864 0 0.425125628140704 Olfactory transduction(K)(0.9984906) 379 ATP6AP1 23q28 0 0 7 6 147 35 1412 0.3864 0 0.160804020100503 Epithelial cell signaling in Helicobacter pylori infection(K)(0.9969342)-Lysosome(K)(0.999097)-Metabolic pathways(K)(0.9983102)-Oxidative phosphorylation(K)(0.9981116)-Phagosome(K)(0.9994834)-Vibrio cholerae infection(K)(0.9981134) 380 NDUFB1 14q32.12 0 0 0 3 188 35 1332 0.3864 0 0.191959798994975 Alzheimer's disease(K)(0.9958972)-Glucose Regulation of Insulin Secretion(R)(0.9968418)-Huntington's disease(K)(0.998422)-Metabolic pathways(K)(0.999236)-Oxidative phosphorylation(K)(0.9932606)-Parkinson's disease(K)(0.997843) 381 IL2 4q27 0 1 1 0 116 34 1172 0.3909 1 0.118592964824121 Autoimmune thyroid disease(K)(0.98671)-BMP receptor signaling(N)(0.997611)-Chagas disease(K)(0.9975812)-Cytokine-cytokine receptor interaction(K)(0.9982338)-Endothelins(N)(0.9955208)-Glypican pathway(N)(0.9962284)-Graft-versus-host disease(K)(0.9865372)-IFN-gamma pathway(N)(0.9982498)-IL1-mediated signaling events(N)(0.9918914)-IL12-mediated signaling events(N)(0.9966944)-IL2-mediated signaling events(N)(0.9658336)-IL23-mediated signaling events(N)(0.9875616)-Intestinal immune network for IgA production(K)(0.9747546)-Jak-STAT signaling pathway(K)(0.9971166)-Plasma membrane estrogen receptor signaling(N)(0.997579)-Regulation of Telomerase(N)(0.9982188)-T cell receptor signaling pathway(K)(0.9951024)-TCR signaling in naive CD4+ T cells(N)(0.9959218)-TNF receptor signaling pathway(N)(0.9970796)-Type I diabetes mellitus(K)(0.989796)-il-2 receptor beta chain in t cell activation(B)(0.9866726) 382 NCAM1 11q23.1 0 0 1 13 374 34 417 0.3909 0 0.389949748743719 Cell adhesion molecules (CAMs)(K)(0.998143)-Prion diseases(K)(0.9966124)-Proteogylcan syndecan-mediated signaling events(N)(0.9983984) 383 MYO16 13q33.3 0 0 2 7 259 34 46 0.3909 0 0.269346733668342 Nicotinic acetylcholine receptor signaling pathway(P)(0.9988788) 384 OPRD1 1p35.3 0 0 0 3 237 34 490 0.3909 0 0.241206030150754 Class A/1 (Rhodopsin-like receptors)(R)(0.9984496)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.998441)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9981724)-Neuroactive ligand-receptor interaction(K)(0.996876)-Receptor-ligand complexes bind G proteins(R)(0.9942092) 385 PIK3CD 1p36.22 0 0 0 2 239 33 1596 0.3917 0 0.242211055276382 Aldosterone-regulated sodium reabsorption(K)(0.9954614)-Alpha6Beta4Integrin(C)(0.9920362)-Amoebiasis(K)(0.9976774)-Apoptosis signaling pathway(P)(0.9880642)-Apoptosis(K)(0.9903342)-B cell receptor signaling pathway(K)(0.9949444)-Bacterial invasion of epithelial cells(K)(0.9869436)-Chagas disease(K)(0.996617)-Chemokine signaling pathway(K)(0.998778)-EGF receptor signaling pathway(P)(0.9339848)-EGFR1(C)(0.9970624)-Endothelin signaling pathway(P)(0.9870216)-ErbB signaling pathway(K)(0.972531)-FGF signaling pathway(P)(0.9758896)-Fc gamma R-mediated phagocytosis(K)(0.9969368)-Focal adhesion(K)(0.992886)-Hypoxia response via HIF activation(P)(0.9697)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.985705)-Inositol phosphate metabolism(K)(0.9773384)-Insulin signaling pathway(K)(0.999221)-Integrin signalling pathway(P)(0.9985832)-Jak-STAT signaling pathway(K)(0.9988674)-Leukocyte transendothelial migration(K)(0.9987298)-Natural killer cell mediated cytotoxicity(K)(0.9962464)-Neurotrophin signaling pathway(K)(0.9970114)-Pathways in cancer(K)(0.9983248)-Phosphatidylinositol signaling system(K)(0.9976692)-Progesterone-mediated oocyte maturation(K)(0.9972248)-Prostate cancer(K)(0.9808286)-Regulation of actin cytoskeleton(K)(0.9996034)-T cell receptor signaling pathway(K)(0.9908296)-Toll-like receptor signaling pathway(K)(0.9974482)-Type II diabetes mellitus(K)(0.9936574)-VEGF signaling pathway(K)(0.9703766)-mTOR signaling pathway(K)(0.9908142) 386 C3 19p13.3 0 0 0 2 152 33 550 0.3917 0 0.154773869346734 Chagas disease(K)(0.9975732)-Complement and coagulation cascades(K)(0.9960956)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9968638)-Innate Immunity Signaling(R)(0.997071)-Leishmaniasis(K)(0.9952424)-Phagosome(K)(0.9975944)-Systemic lupus erythematosus(K)(0.998718) 387 SHMT1 17p11.2 0 2 6 5 366 33 1130 0.3917 0 0.380904522613065 Glycine, serine and threonine metabolism(K)(0.9977718)-Metabolic pathways(K)(0.9992412)-One carbon pool by folate(K)(0.9977874) 388 PDHA1 23p22.12 0 0 3 6 157 33 1243 0.3917 0 0.166834170854271 Glucose Regulation of Insulin Secretion(R)(0.9990728)-Metabolic pathways(K)(0.9987238)-Metabolism of carbohydrates(R)(0.9985328)-Pyruvate metabolism(K)(0.9967382)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.996977)-Valine, leucine and isoleucine biosynthesis(K)(0.9957452) 389 FCGR3A 1q23.3 0 0 11 0 44 33 575 0.3917 0 0.0552763819095477 Fc gamma R-mediated phagocytosis(K)(0.9982028)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9986172)-Leishmaniasis(K)(0.9976406)-Natural killer cell mediated cytotoxicity(K)(0.9985616)-Phagosome(K)(0.9993898)-Systemic lupus erythematosus(K)(0.9969046)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.995617) 390 ZFYVE9 1p32.3 0 0 1 1 178 33 824 0.3917 0 0.180904522613065 Endocytosis(K)(0.9986744)-Glypican pathway(N)(0.9931424)-IFN-gamma pathway(N)(0.9968524)-TGF-beta signaling pathway(K)(0.9981426)-TGF-beta signaling pathway(P)(0.9968928)-TGFBR(C)(0.9982398) 391 MVD 16q24.3 0 0 2 11 474 33 1187 0.3917 0 0.489447236180905 Metabolic pathways(K)(0.9986008)-Metabolism of lipids and lipoproteins(R)(0.9977082)-Terpenoid backbone biosynthesis(K)(0.997657) 392 RPS21 20q13.33 0 3 22 0 31 33 313 0.3917 0 0.0562814070351759 Influenza Life Cycle(R)(0.9986288)-Metabolism of proteins(R)(0.9987354) 393 MAPK14 6p21.31 0 0 1 2 80 32 2069 0.3938 0 0.0834170854271357 Alzheimer disease-amyloid secretase pathway(P)(0.9923594)-Amyotrophic lateral sclerosis (ALS)(K)(0.9941144)-Angiogenesis(P)(0.9915234)-Angiopoietin receptor Tie2-mediated signaling(N)(0.976801)-BMP receptor signaling(N)(0.9889068)-Chagas disease(K)(0.9966988)-EGF receptor signaling pathway(P)(0.9809774)-EGFR1(C)(0.9982092)-Endothelins(N)(0.9865732)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9851612)-FGF signaling pathway(P)(0.920073)-Glypican pathway(N)(0.9927068)-GnRH signaling pathway(K)(0.9929388)-IFN-gamma pathway(N)(0.983774)-IL1-mediated signaling events(N)(0.9545856)-IL12-mediated signaling events(N)(0.994946)-IL2-mediated signaling events(N)(0.9939068)-IL23-mediated signaling events(N)(0.991003)-IL6-mediated signaling events(N)(0.990445)-Leishmaniasis(K)(0.8376206)-Leukocyte transendothelial migration(K)(0.9983902)-MAPK signaling pathway(K)(0.9988328)-NOD-like receptor signaling pathway(K)(0.9927008)-Neurotrophin signaling pathway(K)(0.9870956)-Oxidative stress response(P)(0.956737)-Plasma membrane estrogen receptor signaling(N)(0.9963582)-Progesterone-mediated oocyte maturation(K)(0.993718)-RIG-I-like receptor signaling pathway(K)(0.9975842)-Regulation of retinoblastoma protein(N)(0.997347)-Retinoic acid receptors-mediated signaling(N)(0.995105)-Shigellosis(K)(0.9956306)-Signaling by Aurora kinases(N)(0.9714874)-Signaling events regulated by Ret tyrosine kinase(N)(0.9883688)-Signalling by NGF(R)(0.9983152)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9907026)-T cell receptor signaling pathway(K)(0.964233)-TCR signaling in naive CD4+ T cells(N)(0.988321)-TGF-beta signaling pathway(P)(0.9956456)-TGFBR(C)(0.997354)-TNF receptor signaling pathway(N)(0.9773414)-TRAIL signaling pathway(N)(0.9950738)-Thromboxane A2 receptor signaling(N)(0.984742)-Toll-like receptor signaling pathway(K)(0.9942582)-VEGFR3 signaling in lymphatic endothelium(N)(0.8860452)-actions of nitric oxide in the heart(B)(0.9933524)-agrin in postsynaptic differentiation(B)(0.9968688)-akap95 role in mitosis and chromosome dynamics(B)(0.9447932)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9705288)-atm signaling pathway(B)(0.9213742)-b cell survival pathway(B)(0.9644544)-bone remodeling(B)(0.9336158)-cdk regulation of dna replication(B)(0.996415)-chrebp regulation by carbohydrates and camp(B)(0.9934586)-how progesterone initiates the oocyte maturation(B)(0.9181796)-il-10 anti-inflammatory signaling pathway(B)(0.9552434)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9324848)-integrin signaling pathway(B)(0.9853858)-keratinocyte differentiation(B)(0.970745)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9947286)-multi-step regulation of transcription by pitx2(B)(0.9770788)-nfat and hypertrophy of the heart (B)(0.9971498)-p38 mapk signaling pathway(B)(0.9564784)-p53 pathway feedback loops 2(P)(0.930678)-p53 signaling pathway(B)(0.8129954)-p75(NTR)-mediated signaling(N)(0.9977452)-phosphoinositides and their downstream targets(B)(0.9831808)-phospholipase c-epsilon pathway(B)(0.9470756)-phospholipids as signalling intermediaries(B)(0.9340512)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.9762654)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9814934)-regulation of eif-4e and p70s6 kinase(B)(0.8295794)-regulation of eif2(B)(0.987048)-repression of pain sensation by the transcriptional regulator dream(B)(0.9465414)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9944124)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.9335084)-role of ran in mitotic spindle regulation(B)(0.9755092)-segmentation clock(B)(0.964102)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9709466)-telomeres telomerase cellular aging and immortality(B)(0.8723784)-the igf-1 receptor and longevity(B)(0.8519738)-tpo signaling pathway(B)(0.9346112)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.8721704)-vegf hypoxia and angiogenesis(B)(0.8687514) 394 CENPK 5q12.3 0 0 0 1 155 32 96 0.3938 0 0.15678391959799 M Phase(R)(0.9993004) 395 FGF22 19p13.3 0 0 3 2 205 32 653 0.3938 0 0.21105527638191 MAPK signaling pathway(K)(0.9995836)-Pathways in cancer(K)(0.9986716)-Regulation of actin cytoskeleton(K)(0.9979666)-Signaling by FGFR(R)(0.998481) 396 SPCS2 11q13.4 0 9 15 4 122 32 61 0.3938 0 0.150753768844221 Insulin Synthesis and Secretion(R)(0.9979472)-Protein export(K)(0.998071)-Vasopressin synthesis(P)(0.9917974) 397 NUP93 16q13 0 0 2 7 468 32 429 0.3938 0 0.479396984924623 HIV Life Cycle(R)(0.9965106)-Host Interactions of HIV factors(R)(0.998889)-Influenza Life Cycle(R)(0.9984614)-Metabolism of carbohydrates(R)(0.9962758)-Metabolism of non-coding RNA(R)(0.9946086)-Transport of Mature Transcript to Cytoplasm(R)(0.9918984) 398 GSK3B 3q13.33 0 0 0 1 47 32 2291 0.3938 0 0.0482412060301508 Alzheimer disease-presenilin pathway(P)(0.9944308)-Alzheimer's disease(K)(0.9984504)-Androgen-mediated signaling(N)(0.9605114)-Angiogenesis(P)(0.9797346)-Axon guidance(K)(0.9980358)-B cell receptor signaling pathway(K)(0.9848524)-BMP receptor signaling(N)(0.9886148)-Cell cycle(K)(0.9973558)-Chemokine signaling pathway(K)(0.9983758)-Endothelins(N)(0.9833914)-ErbB signaling pathway(K)(0.983092)-Focal adhesion(K)(0.9985196)-Glypican pathway(N)(0.9842778)-Hedgehog signaling pathway(K)(0.9782174)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9965294)-IFN-gamma pathway(N)(0.9927304)-IL1-mediated signaling events(N)(0.990153)-Insulin signaling pathway(K)(0.999129)-Interleukin signaling pathway(P)(0.985133)-LPA receptor mediated events(N)(0.988587)-NOTCH(C)(0.994274)-Neurotrophin signaling pathway(K)(0.9824174)-Pathways in cancer(K)(0.9991236)-Plasma membrane estrogen receptor signaling(N)(0.9631374)-Prostate cancer(K)(0.9890634)-Proteogylcan syndecan-mediated signaling events(N)(0.998231)-Reelin signaling pathway(N)(0.9673878)-Signaling by Aurora kinases(N)(0.9530986)-Signaling by Wnt(R)(0.9525108)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9775764)-Signaling events mediated by the Hedgehog family(N)(0.9906036)-Signalling by NGF(R)(0.9931716)-TNF alpha/NF-kB(C)(0.9980442)-TNF receptor signaling pathway(N)(0.9872192)-TRAIL signaling pathway(N)(0.9859172)-Wnt signaling pathway(K)(0.9925608)-Wnt signaling pathway(P)(0.9987292)-Wnt(C)(0.9939946)-p75(NTR)-mediated signaling(N)(0.9969362) 399 CHRNA7 15q13.3 0 0 0 8 223 32 436 0.3938 0 0.232160804020101 Alzheimer disease-amyloid secretase pathway(P)(0.9986988)-Calcium signaling pathway(K)(0.9991062)-Neuroactive ligand-receptor interaction(K)(0.9989912) 400 ANPEP 15q26.1 0 3 2 0 119 31 1251 0.3992 0 0.124623115577889 Glutathione metabolism(K)(0.998057)-Hematopoietic cell lineage(K)(0.9984252)-Metabolic pathways(K)(0.998241)-Renin-angiotensin system(K)(0.9975562) 401 RET 10q11.21 0 0 5 1 95 31 704 0.3992 1 0.101507537688442 Endocytosis(K)(0.99835)-Endothelin signaling pathway(P)(0.998924)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9983128)-Metabotropic glutamate receptor group I pathway(P)(0.9933426)-Pathways in cancer(K)(0.999028)-Signaling events regulated by Ret tyrosine kinase(N)(0.9966926) 402 POLR2D 2q14.3 0 0 0 1 118 31 1635 0.3992 0 0.119597989949749 DNA Repair(R)(0.998793)-Formation and Maturation of mRNA Transcript(R)(0.9977234)-HIV Life Cycle(R)(0.9970506)-Huntington's disease(K)(0.9982146)-Influenza Life Cycle(R)(0.998986)-Metabolic pathways(K)(0.9979246)-Purine metabolism(K)(0.9989014)-Pyrimidine metabolism(K)(0.9948534)-Regulatory RNA pathways(R)(0.9953676)-Transcription(R)(0.9987146)-mRNA Processing(R)(0.994479) 403 PGM2 4p14 0 0 0 3 154 31 1203 0.3992 0 0.157788944723618 Amino sugar and nucleotide sugar metabolism(K)(0.9969832)-Metabolic pathways(K)(0.9986414)-Pentose phosphate pathway(K)(0.9747108)-Purine metabolism(K)(0.9990418)-Starch and sucrose metabolism(K)(0.9976522) 404 MAN1A1 6q22.31 0 0 7 4 219 30 1281 0.3993 0 0.231155778894472 Metabolic pathways(K)(0.9992524)-N-Glycan biosynthesis(K)(0.9993016)-Protein processing in endoplasmic reticulum(K)(0.9990902)-er associated degradation (erad) pathway(B)(0.995949) 405 GLUD2 23q24 0 0 1 5 174 30 1153 0.3993 0 0.180904522613065 Alanine, aspartate and glutamate metabolism(K)(0.9978468)-Metabolic pathways(K)(0.9994954)-Nitrogen metabolism(K)(0.9984608)-Proximal tubule bicarbonate reclamation(K)(0.9984676) 406 FAU 11q13.1 0 0 3 1 118 30 313 0.3993 0 0.122613065326633 Influenza Life Cycle(R)(0.9984356)-Metabolism of proteins(R)(0.9993804) 407 DNM1 9q34.11 0 0 2 0 146 30 692 0.3993 0 0.148743718592965 Bacterial invasion of epithelial cells(K)(0.9975186)-EGFR1(C)(0.9992142)-Endocytosis(K)(0.9975968)-EphrinB-EPHB pathway(N)(0.9768082)-Fc gamma R-mediated phagocytosis(K)(0.9970962)-Gap junction trafficking and regulation(R)(0.9937328)-Signalling by NGF(R)(0.998346)-Thromboxane A2 receptor signaling(N)(0.9963816)-endocytotic role of ndk phosphins and dynamin(B)(0.9887288)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9965544)-p75(NTR)-mediated signaling(N)(0.9987506)-ß-arrestins in gpcr desensitization(B)(0.9689068) 408 DVL2 17p13.1 0 0 0 4 395 30 577 0.3993 0 0.401005025125628 Alzheimer disease-presenilin pathway(P)(0.9986202)-Melanogenesis(K)(0.9985358)-Notch signaling pathway(K)(0.9970286)-Pathways in cancer(K)(0.999006)-Wnt signaling pathway(K)(0.9984792)-Wnt(C)(0.9966418) 409 SMARCC1 3p21.31 0 0 0 0 210 30 440 0.3993 0 0.21105527638191 Androgen-mediated signaling(N)(0.985535)-Wnt signaling pathway(P)(0.999139)-control of gene expression by vitamin d receptor(B)(0.9965436)-the information processing pathway at the ifn beta enhancer(B)(0.9967808) 410 RFC1 4p14 0 0 1 4 170 30 277 0.3993 0 0.175879396984925 DNA Repair(R)(0.9988466)-DNA Replication(R)(0.9940498)-DNA replication(K)(0.9948544)-FAS signaling pathway (CD95)(N)(0.9971454)-Mismatch repair(K)(0.9957218)-Nucleotide excision repair(K)(0.9914692)-S Phase(R)(0.99652)-Telomere Maintenance(R)(0.9966416)-alk in cardiac myocytes(B)(0.9987998) 411 SYN3 22q12.3 0 0 5 3 321 30 42 0.3993 0 0.330653266331658 Synaptic Transmission(R)(0.9980604) 412 C17orf48 17p13.1 0 0 1 7 443 30 239 0.3993 0 0.453266331658291 Glycerophospholipid metabolism(K)(0.9980366)-Purine metabolism(K)(0.9985568) 413 OR4D2 17q22 0 3 25 0 82 30 413 0.3993 0 0.110552763819095 Olfactory transduction(K)(0.9992062) 414 PTBP1 19p13.3 0 0 3 1 206 29 291 0.3998 0 0.21105527638191 Formation and Maturation of mRNA Transcript(R)(0.9983728)-Influenza Life Cycle(R)(0.9991798)-internal ribosome entry pathway(B)(0.996594) 415 CDKN2A 9p21.3 0 0 3 16 183 29 1031 0.3998 1 0.203015075376884 Androgen-mediated signaling(N)(0.980155)-Cell cycle(K)(0.9991924)-Chronic myeloid leukemia(K)(0.8110778)-FOXM1 transcription factor network(N)(0.9945198)-Glioma(K)(0.9941202)-Glypican pathway(N)(0.9963316)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9934264)-Melanoma(K)(0.98525)-Pathways in cancer(K)(0.9981182)-Regulation of retinoblastoma protein(N)(0.9985636)-TRAIL signaling pathway(N)(0.9957782)-ctcf: first multivalent nuclear factor(B)(0.9929796)-p53 signaling pathway(K)(0.9963092)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.987327) 416 EFNA5 5q21.3 0 0 0 4 135 29 168 0.3998 0 0.139698492462312 Axon guidance(K)(0.999013)-EphrinA-EPHA pathway(N)(0.9859654)-EphrinB-EPHB pathway(N)(0.985326) 417 SMAD9 13q13.3 0 1 2 6 281 29 314 0.3998 0 0.291457286432161 BMP receptor signaling(N)(0.9984116)-Signaling by BMP(R)(0.9975338)-TGF-beta signaling pathway(K)(0.9984952)-TGF-beta signaling pathway(P)(0.9976224) 418 SYT1 12q21.2 0 0 4 0 78 29 58 0.3998 0 0.0824120603015075 Botulinum neurotoxicity(R)(0.998626)-Synaptic Transmission(R)(0.996713) 419 TCAP 17q12 0 80 33 1 140 29 31 0.3998 0 0.255276381909548 Muscle contraction(R)(0.9992598) 420 ABCA7 19p13.3 0 0 2 1 194 29 59 0.3998 0 0.197989949748744 ABC transporters(K)(0.998138)-Transmembrane transport of small molecules(R)(0.9971718) 421 GLI2 2q14.2 0 0 2 1 119 29 385 0.3998 0 0.122613065326633 Hedgehog signaling pathway(K)(0.9991218)-Hedgehog(C)(0.9956448)-Pathways in cancer(K)(0.9983034)-Signaling events mediated by the Hedgehog family(N)(0.997518) 422 ACTA2 10q23.31 0 0 0 2 136 29 620 0.3998 0 0.138693467336683 Alzheimer disease-presenilin pathway(P)(0.9989844)-Huntington disease(P)(0.9982246)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9964048)-Vascular smooth muscle contraction(K)(0.9979014)-Wnt signaling pathway(P)(0.9982466) 423 RFXAP 13q13.3 0 1 2 6 276 29 104 0.3998 0 0.28643216080402 Antigen processing and presentation(K)(0.9972692)-Primary immunodeficiency(K)(0.9981132) 424 LSP1 11p15.5 0 0 1 0 179 28 728 0.4046 0 0.180904522613065 BMP receptor signaling(N)(0.99816)-Glypican pathway(N)(0.9986256)-IFN-gamma pathway(N)(0.9976782)-IL1-mediated signaling events(N)(0.997182)-Plasma membrane estrogen receptor signaling(N)(0.99869)-TNF receptor signaling pathway(N)(0.9985136) 425 RPS6 9p22.1 0 1 2 4 210 28 1050 0.4046 0 0.218090452261307 Endothelins(N)(0.9970124)-Glypican pathway(N)(0.9985214)-IFN-gamma pathway(N)(0.996104)-IL2-mediated signaling events(N)(0.9963832)-Influenza Life Cycle(R)(0.9970064)-Insulin signaling pathway(K)(0.9990658)-Metabolism of proteins(R)(0.99817)-Signaling by Insulin receptor(R)(0.9838882)-TRAIL signaling pathway(N)(0.9977978)-mTOR signaling pathway(K)(0.9965028)-regulation of eif-4e and p70s6 kinase(B)(0.951987) 426 APP 21q21.3 0 1 3 4 78 28 1001 0.4046 0 0.0864321608040201 Alzheimer disease-amyloid secretase pathway(P)(0.9954234)-Alzheimer disease-presenilin pathway(P)(0.999173)-Alzheimer's disease(K)(0.9952122)-Formation of Platelet plug(R)(0.9990126)-Glypican pathway(N)(0.9971154)-NOTCH(C)(0.9966884)-TNF receptor signaling pathway(N)(0.9954536)-TRAIL signaling pathway(N)(0.9968254)-p75(NTR)-mediated signaling(N)(0.9983242) 427 CACNA1D 3p21.1 0 0 2 0 186 28 806 0.4046 0 0.18894472361809 5HT2 type receptor mediated signaling pathway(P)(0.9820154)-Alzheimer's disease(K)(0.9975634)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9970074)-Calcium signaling pathway(K)(0.9994408)-Cardiac muscle contraction(K)(0.9945802)-Glucose Regulation of Insulin Secretion(R)(0.9981432)-GnRH signaling pathway(K)(0.996406)-Hypertrophic cardiomyopathy (HCM)(K)(0.9984788)-MAPK signaling pathway(K)(0.9989042)-Type II diabetes mellitus(K)(0.9982724)-Vascular smooth muscle contraction(K)(0.997495) 428 A2M 12p13.31 0 2 5 2 84 28 438 0.4046 0 0.0934673366834171 Complement and coagulation cascades(K)(0.9955606)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9988658)-Formation of Platelet plug(R)(0.9983874)-IL6-mediated signaling events(N)(0.9976506)-Metabolism of lipids and lipoproteins(R)(0.9968858)-Signaling by Rho GTPases(R)(0.999074) 429 OR2AG2 11p15.4 0 0 0 0 150 28 413 0.4046 0 0.150753768844221 Olfactory transduction(K)(0.9993408) 430 GMDS 6p25.3 0 0 1 5 91 27 1134 0.406 0 0.0974874371859296 Amino sugar and nucleotide sugar metabolism(K)(0.9992928)-Fructose and mannose metabolism(K)(0.997938)-Metabolic pathways(K)(0.9988622) 431 SQLE 8q24.13 0 3 64 1 9 27 1123 0.406 0 0.0773869346733668 Metabolic pathways(K)(0.9987638)-Steroid biosynthesis(K)(0.9950942) 432 PRKACA 19p13.12 0 0 5 1 97 27 2577 0.406 0 0.103517587939698 Amoebiasis(K)(0.9951278)-Apoptosis(K)(0.981693)-BMP receptor signaling(N)(0.990333)-Calcium signaling pathway(K)(0.9985164)-Chemokine signaling pathway(K)(0.9973694)-Dilated cardiomyopathy(K)(0.862436)-Endothelins(N)(0.9765036)-G2/M Transition(R)(0.9983036)-Gap junction(K)(0.9932)-Gastric acid secretion(K)(0.9926822)-Glypican pathway(N)(0.9947942)-GnRH signaling pathway(K)(0.9844846)-Hedgehog signaling pathway(K)(0.9737794)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9945308)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.9706774)-IFN-gamma pathway(N)(0.9869354)-IL1-mediated signaling events(N)(0.9870202)-Insulin signaling pathway(K)(0.9945332)-LPA receptor mediated events(N)(0.965638)-Long-term potentiation(K)(0.957989)-MAPK signaling pathway(K)(0.9981402)-Melanogenesis(K)(0.9476036)-Metabolism of lipids and lipoproteins(R)(0.999176)-Olfactory transduction(K)(0.99924)-Oocyte meiosis(K)(0.9909674)-Opioid Signalling(R)(0.993043)-Plasma membrane estrogen receptor signaling(N)(0.9656984)-Prion diseases(K)(0.985543)-Progesterone-mediated oocyte maturation(K)(0.9505432)-Proteogylcan syndecan-mediated signaling events(N)(0.9980924)-Retinoic acid receptors-mediated signaling(N)(0.9875898)-Salivary secretion(K)(0.9925382)-Signaling by Aurora kinases(N)(0.9721258)-Signaling events mediated by HDAC Class I(N)(0.9962936)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.994316)-Signaling events mediated by the Hedgehog family(N)(0.9922902)-Signalling by NGF(R)(0.9948048)-TCR signaling in naive CD4+ T cells(N)(0.9863398)-TNF alpha/NF-kB(C)(0.9988546)-TNF receptor signaling pathway(N)(0.9802016)-Taste transduction(K)(0.9927684)-Thromboxane A2 receptor signaling(N)(0.9702234)-Vascular smooth muscle contraction(K)(0.9963166)-Vasopressin-regulated water reabsorption(K)(0.9937056)-Vibrio cholerae infection(K)(0.992198)-Wnt signaling pathway(K)(0.998577)-a4b1 and a4b7 Integrin signaling(N)(0.8987218) 433 INPP5D 2q37.1 0 0 0 0 130 27 1076 0.406 0 0.130653266331658 B cell receptor signaling pathway(K)(0.9927828)-Cell surface interactions at the vascular wall(R)(0.9983288)-EPO signaling pathway(N)(0.9582702)-Fc epsilon RI signaling pathway(K)(0.994283)-Fc gamma R-mediated phagocytosis(K)(0.9986724)-Fc-epsilon receptor I signaling in mast cells(N)(0.9914312)-Glypican pathway(N)(0.9936216)-IFN-gamma pathway(N)(0.9987672)-Insulin signaling pathway(K)(0.998331)-Phosphatidylinositol signaling system(K)(0.9985246)-Plasma membrane estrogen receptor signaling(N)(0.9946664)-Proteogylcan syndecan-mediated signaling events(N)(0.9958044)-TCR signaling in naive CD4+ T cells(N)(0.9962724)-TCR signaling(R)(0.983918)-TRAIL signaling pathway(N)(0.9987868) 434 HMBS 11q23.3 0 0 2 12 349 27 1134 0.406 0 0.364824120603015 Metabolic pathways(K)(0.9992282)-Porphyrin and chlorophyll metabolism(K)(0.9984524)-hemoglobins chaperone(B)(0.9858384) 435 TNFRSF1A 12p13.31 0 1 4 1 83 27 1594 0.406 0 0.0894472361809045 Adipocytokine signaling pathway(K)(0.9975062)-Alzheimer's disease(K)(0.9969976)-Amyotrophic lateral sclerosis (ALS)(K)(0.9958928)-Apoptosis signaling pathway(P)(0.9659558)-Apoptosis(K)(0.9885182)-Apoptosis(R)(0.9979226)-Chagas disease(K)(0.9977746)-Cytokine-cytokine receptor interaction(K)(0.9984408)-Glypican pathway(N)(0.9944974)-IL1-mediated signaling events(N)(0.992514)-IL12-mediated signaling events(N)(0.9983562)-IL2-mediated signaling events(N)(0.995151)-IL23-mediated signaling events(N)(0.9837646)-LPA receptor mediated events(N)(0.9947164)-MAPK signaling pathway(K)(0.9992848)-Signaling by Aurora kinases(N)(0.9873274)-Signaling events mediated by HDAC Class I(N)(0.9983326)-Signaling events regulated by Ret tyrosine kinase(N)(0.9940678)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9960496)-TCR signaling in naive CD4+ T cells(N)(0.9900412)-TNF alpha/NF-kB(C)(0.9991764)-TNF receptor signaling pathway(N)(0.99538)-keratinocyte differentiation(B)(0.9856644)-p75(NTR)-mediated signaling(N)(0.9970564) 436 NMBR 6q24.1 0 1 5 1 191 27 381 0.406 0 0.198994974874372 Class A/1 (Rhodopsin-like receptors)(R)(0.9989288)-Neuroactive ligand-receptor interaction(K)(0.9992084)-Receptor-ligand complexes bind G proteins(R)(0.9984612) 437 ITGA3 17q21.33 0 6 27 0 105 27 902 0.406 0 0.138693467336683 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9834178)-Cell surface interactions at the vascular wall(R)(0.9962108)-Dilated cardiomyopathy(K)(0.9971906)-ECM-receptor interaction(K)(0.9955432)-Focal adhesion(K)(0.9972902)-Hematopoietic cell lineage(K)(0.9984958)-Hypertrophic cardiomyopathy (HCM)(K)(0.992699)-IL23-mediated signaling events(N)(0.9962452)-Integrin cell surface interactions(R)(0.9960354)-Integrin signalling pathway(P)(0.998609)-Pathways in cancer(K)(0.99903)-Reelin signaling pathway(N)(0.9952204)-Regulation of actin cytoskeleton(K)(0.9986434) 438 NFAT5 16q22.1 0 0 0 14 518 27 469 0.406 0 0.534673366834171 Axon guidance(K)(0.9998574)-B cell receptor signaling pathway(K)(0.9965488)-Natural killer cell mediated cytotoxicity(K)(0.999236)-T cell receptor signaling pathway(K)(0.9935556)-VEGF signaling pathway(K)(0.998148)-Wnt signaling pathway(K)(0.997736) 439 PCDH11X 23q21.31 0 0 1 9 193 27 299 0.406 0 0.204020100502513 Wnt signaling pathway(P)(0.9992722) 440 CYP2C18 10q23.33 0 0 2 2 144 26 1243 0.4062 0 0.148743718592965 Arachidonic acid metabolism(K)(0.9948656)-Biological oxidations(R)(0.9957572)-Drug metabolism - cytochrome P450(K)(0.9953278)-FOXA transcription factor networks(N)(0.9778664)-Metabolic pathways(K)(0.9988488)-Metabolism of xenobiotics by cytochrome P450(K)(0.9974754)-Retinol metabolism(K)(0.995816) 441 F9 23q27.1 0 0 3 5 151 26 278 0.4062 0 0.159798994974874 Complement and coagulation cascades(K)(0.998892)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9964212)-Metabolism of proteins(R)(0.998982)-intrinsic prothrombin activation pathway(B)(0.987694) 442 BRCA2 13q13.1 0 0 5 8 266 26 457 0.4062 1 0.280402010050251 DNA Repair(R)(0.9975)-FOXM1 transcription factor network(N)(0.9981366)-Homologous recombination(K)(0.996428)-Pathways in cancer(K)(0.9992646)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9961324) 443 ATP6V0D1 16q22.1 0 0 1 9 476 26 1416 0.4062 0 0.488442211055276 Collecting duct acid secretion(K)(0.9873826)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9975)-Lysosome(K)(0.9989744)-Metabolic pathways(K)(0.9993576)-Oxidative phosphorylation(K)(0.9980058)-Phagosome(K)(0.9992454)-Vibrio cholerae infection(K)(0.9969648) 444 RCVRN 17p13.1 0 0 0 8 439 26 48 0.4062 0 0.449246231155779 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.997345)-Phototransduction(K)(0.9993844)-visual signal transduction(B)(0.9654714) 445 NFKBIA 14q13.2 0 0 3 0 103 26 1751 0.4062 0 0.106532663316583 Adipocytokine signaling pathway(K)(0.9973318)-Apoptosis signaling pathway(P)(0.9689228)-Apoptosis(K)(0.9888212)-B cell receptor signaling pathway(K)(0.9864838)-Chagas disease(K)(0.9855176)-Chemokine signaling pathway(K)(0.998344)-Cytosolic DNA-sensing pathway(K)(0.9939406)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9974096)-Glypican pathway(N)(0.9969952)-IL1-mediated signaling events(N)(0.967381)-IL12-mediated signaling events(N)(0.995764)-IL2-mediated signaling events(N)(0.9944988)-IL23-mediated signaling events(N)(0.9782252)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.99575)-Integrins in angiogenesis(N)(0.9967242)-LPA receptor mediated events(N)(0.9842108)-Leishmaniasis(K)(0.9924866)-NOD-like receptor signaling pathway(K)(0.989794)-NOTCH(C)(0.9971442)-Neurotrophin signaling pathway(K)(0.989441)-Pathways in cancer(K)(0.9993232)-Prostate cancer(K)(0.9895328)-RIG-I-like receptor signaling pathway(K)(0.9943142)-Shigellosis(K)(0.9921308)-Signaling by Aurora kinases(N)(0.9865656)-Signaling events mediated by HDAC Class I(N)(0.9986128)-Signaling events regulated by Ret tyrosine kinase(N)(0.9828044)-Signalling by NGF(R)(0.9987346)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9963958)-T cell receptor signaling pathway(K)(0.96954)-TCR signaling in naive CD4+ T cells(N)(0.9848068)-TNF alpha/NF-kB(C)(0.998919)-TNF receptor signaling pathway(N)(0.986818)-Toll-like receptor signaling pathway(K)(0.9915908)-lectin induced complement pathway(B)(0.9661834)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9927964)-p75(NTR)-mediated signaling(N)(0.9973516) 446 ELK1 23p11.23 0 0 0 5 157 26 1404 0.4062 0 0.162814070351759 Angiopoietin receptor Tie2-mediated signaling(N)(0.9934032)-EGFR1(C)(0.9980264)-Endometrial cancer(K)(0.9932332)-ErbB signaling pathway(K)(0.9874318)-Focal adhesion(K)(0.9986738)-Glypican pathway(N)(0.9943446)-GnRH signaling pathway(K)(0.9927984)-ID(C)(0.9966606)-Insulin signaling pathway(K)(0.997853)-Leishmaniasis(K)(0.99365)-MAPK signaling pathway(K)(0.9983586)-Oxidative stress response(P)(0.9699834)-Parkinson disease(P)(0.9950728)-Prion diseases(K)(0.9940072)-Proteogylcan syndecan-mediated signaling events(N)(0.998578)-Signalling by NGF(R)(0.998881)-Sphingosine 1-phosphate (S1P) pathway(N)(0.996803)-TCR signaling in naive CD4+ T cells(N)(0.9931202)-TRAIL signaling pathway(N)(0.9959696)-fc epsilon receptor i signaling in mast cells(B)(0.965664)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9890136)-p38 mapk signaling pathway(B)(0.9868896)-p75(NTR)-mediated signaling(N)(0.9967442)-t cell receptor signaling pathway(B)(0.9711526)-toll-like receptor pathway(B)(0.9953674)-tpo signaling pathway(B)(0.9720152) 447 BTRC 10q24.32 0 0 2 0 155 26 975 0.4062 0 0.157788944723618 APC/C-mediated degradation of cell cycle proteins(R)(0.9889676)-Circadian rhythm - mammal(K)(0.9903442)-Hedgehog signaling pathway(K)(0.9984524)-Host Interactions of HIV factors(R)(0.9982958)-Oocyte meiosis(K)(0.9984644)-Shigellosis(K)(0.996771)-TGFBR(C)(0.9977444)-TNF alpha/NF-kB(C)(0.9985622)-Ubiquitin mediated proteolysis(K)(0.9988082)-Wnt signaling pathway(K)(0.996207)-Wnt signaling pathway(P)(0.9986264)-Wnt(C)(0.9963578)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9923056)-wnt signaling pathway(B)(0.9890586) 448 POLR2F 22q13.1 0 1 3 2 284 26 1635 0.4062 0 0.291457286432161 DNA Repair(R)(0.9981116)-Formation and Maturation of mRNA Transcript(R)(0.9985758)-HIV Life Cycle(R)(0.993923)-Huntington's disease(K)(0.998661)-Influenza Life Cycle(R)(0.9985656)-Metabolic pathways(K)(0.9993726)-Purine metabolism(K)(0.9979784)-Pyrimidine metabolism(K)(0.98877)-Regulatory RNA pathways(R)(0.9939372)-Transcription(R)(0.9977184)-mRNA Processing(R)(0.9882898) 449 KLHL9 9p21.3 0 0 3 11 196 26 223 0.4062 0 0.21105527638191 Signaling by Aurora kinases(N)(0.9965648)-Ubiquitin mediated proteolysis(K)(0.9976614) 450 CCNC 6q16.3 0 0 2 5 252 26 33 0.4062 0 0.260301507537688 Generic Transcription Pathway(R)(0.9984966) 451 CLN5 13q22.3 0 0 1 5 264 26 121 0.4062 0 0.271356783919598 Lysosome(K)(0.9980502) 452 PREP 6q21 0 1 9 4 226 25 9 0.4089 0 0.241206030150754 Vasopressin synthesis(P)(0.9985716) 453 SNAP23 15q15.1 0 0 0 7 191 25 106 0.4089 0 0.198994974874372 5HT2 type receptor mediated signaling pathway(P)(0.99428)-Cortocotropin releasing factor receptor signaling pathway(P)(0.9975308)-Membrane Trafficking(R)(0.9965244)-PNAT(P)(0.9966518)-SNARE interactions in vesicular transport(K)(0.9982136) 454 C8A 1p32.2 0 1 1 1 130 25 380 0.4089 0 0.133668341708543 Amoebiasis(K)(0.9984672)-Complement and coagulation cascades(K)(0.997321)-Innate Immunity Signaling(R)(0.9962638)-Prion diseases(K)(0.9964462)-Systemic lupus erythematosus(K)(0.997589) 455 DDX5 17q24.1 0 3 36 0 75 25 139 0.4089 1 0.114572864321608 Spliceosome(K)(0.9985262)-akap95 role in mitosis and chromosome dynamics(B)(0.9986614) 456 PIK3R5 17p13.1 0 0 0 7 434 25 1374 0.4089 0 0.44321608040201 Aldosterone-regulated sodium reabsorption(K)(0.997538)-Amoebiasis(K)(0.9964358)-Apoptosis(K)(0.992653)-B cell receptor signaling pathway(K)(0.9904328)-Bacterial invasion of epithelial cells(K)(0.9865326)-Chagas disease(K)(0.9937914)-Chemokine signaling pathway(K)(0.9952664)-ErbB signaling pathway(K)(0.9921226)-Fc gamma R-mediated phagocytosis(K)(0.9972484)-Focal adhesion(K)(0.9984758)-Insulin signaling pathway(K)(0.9991174)-Jak-STAT signaling pathway(K)(0.9987354)-Leukocyte transendothelial migration(K)(0.9971674)-Natural killer cell mediated cytotoxicity(K)(0.998104)-Neurotrophin signaling pathway(K)(0.9985)-Pathways in cancer(K)(0.9981742)-Phosphatidylinositol signaling system(K)(0.998308)-Progesterone-mediated oocyte maturation(K)(0.9974012)-Prostate cancer(K)(0.9930616)-Regulation of actin cytoskeleton(K)(0.999113)-T cell receptor signaling pathway(K)(0.9925898)-Toll-like receptor signaling pathway(K)(0.9959646)-Type II diabetes mellitus(K)(0.9921296)-VEGF signaling pathway(K)(0.9863322)-mTOR signaling pathway(K)(0.9897562) 457 WNT7A 3p25.1 0 0 3 0 79 25 785 0.4089 0 0.0824120603015075 Alzheimer disease-presenilin pathway(P)(0.997929)-Angiogenesis(P)(0.997173)-Hedgehog signaling pathway(K)(0.9967338)-Melanogenesis(K)(0.9976956)-Pathways in cancer(K)(0.9991986)-Wnt signaling pathway(K)(0.998261)-Wnt signaling pathway(P)(0.9989638)-Wnt(C)(0.9969328) 458 SSRP1 11q12.1 0 1 4 3 143 25 240 0.4089 0 0.151758793969849 Formation and Maturation of mRNA Transcript(R)(0.9987216)-HIV Life Cycle(R)(0.998532)-Transcription(R)(0.9988368) 459 GRIN3A 9q31.1 0 0 0 1 169 25 395 0.4089 0 0.170854271356784 Huntington disease(P)(0.9974432)-Neuroactive ligand-receptor interaction(K)(0.9986194) 460 USP8 15q21.2 0 0 1 2 186 25 204 0.4089 0 0.189949748743719 Endocytosis(K)(0.9990108) 461 OR52B4 11p15.4 0 0 0 1 161 25 389 0.4089 0 0.162814070351759 Olfactory transduction(K)(0.9985676) 462 HDAC1 1p35.1 0 0 2 0 181 24 1704 0.4129 0 0.18391959798995 Androgen-mediated signaling(N)(0.9608338)-AndrogenReceptor(C)(0.996049)-Cell cycle(K)(0.9992492)-EGFR1(C)(0.9977868)-Glypican pathway(N)(0.9954988)-Huntington's disease(K)(0.9993)-IFN-gamma pathway(N)(0.9960786)-NOTCH(C)(0.9974666)-Notch signaling pathway(K)(0.9917808)-Pathways in cancer(K)(0.9987658)-Regulation of Telomerase(N)(0.9966354)-Regulation of retinoblastoma protein(N)(0.996984)-Retinoic acid receptors-mediated signaling(N)(0.9942162)-Signaling events mediated by HDAC Class I(N)(0.9978702)-Signaling events mediated by the Hedgehog family(N)(0.9958684)-Signalling by NGF(R)(0.998552)-TGFBR(C)(0.9956208)-TNF alpha/NF-kB(C)(0.9980026)-Wnt signaling pathway(P)(0.9985272)-downregulated of mta-3 in er-negative breast tumors(B)(0.9930802)-multi-step regulation of transcription by pitx2(B)(0.9793222)-p53 pathway(P)(0.9834016)-role of mef2d in t-cell apoptosis(B)(0.9734938) 463 RAC2 22q13.1 0 1 0 2 293 24 1546 0.4129 0 0.29748743718593 Adherens junction(K)(0.9962622)-Axon guidance(K)(0.998436)-B cell receptor signaling pathway(K)(0.9930062)-Chemokine signaling pathway(K)(0.9983378)-EGF receptor signaling pathway(P)(0.9913048)-FGF signaling pathway(P)(0.9888212)-Fc epsilon RI signaling pathway(K)(0.9882886)-Fc gamma R-mediated phagocytosis(K)(0.996843)-Focal adhesion(K)(0.994421)-Huntington disease(P)(0.9984016)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9967006)-Integrin signalling pathway(P)(0.996384)-Leukocyte transendothelial migration(K)(0.9975682)-MAPK signaling pathway(K)(0.9975042)-Natural killer cell mediated cytotoxicity(K)(0.9968802)-Pathways in cancer(K)(0.9989698)-Regulation of actin cytoskeleton(K)(0.9981568)-Signaling by Rho GTPases(R)(0.9973204)-VEGF signaling pathway(K)(0.9717224)-Viral myocarditis(K)(0.9969566)-Wnt signaling pathway(K)(0.9974982) 464 HGF 7q21.11 0 0 1 1 68 24 1064 0.4129 0 0.0703517587939698 Cytokine-cytokine receptor interaction(K)(0.9971224)-FAS signaling pathway (CD95)(N)(0.995572)-Focal adhesion(K)(0.9983232)-Formation of Platelet plug(R)(0.9991086)-Malaria(K)(0.9963514)-Pathways in cancer(K)(0.998435)-Plasma membrane estrogen receptor signaling(N)(0.998026)-Proteogylcan syndecan-mediated signaling events(N)(0.9976914) 465 HIST3H3 1q42.13 0 1 21 0 7 24 436 0.4129 0 0.0291457286432161 EGFR1(C)(0.9989668)-Systemic lupus erythematosus(K)(0.997834)-TNF alpha/NF-kB(C)(0.9980952)-Telomere Maintenance(R)(0.997567) 466 TRPV1 17p13.3 0 0 0 6 417 24 444 0.4129 0 0.425125628140704 Neuroactive ligand-receptor interaction(K)(0.997938)-p75(NTR)-mediated signaling(N)(0.9980368) 467 EXTL3 8p21.1 0 0 3 28 345 24 1130 0.4129 0 0.377889447236181 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.997621)-Metabolic pathways(K)(0.9981822) 468 ATG12 5q23.1 0 0 0 1 130 24 91 0.4129 0 0.131658291457286 RIG-I-like receptor signaling pathway(K)(0.9978746)-Regulation of autophagy(K)(0.9983788) 469 NDUFA1 23q24 0 0 1 11 194 24 1332 0.4129 0 0.207035175879397 Alzheimer's disease(K)(0.99809)-Glucose Regulation of Insulin Secretion(R)(0.9965342)-Huntington's disease(K)(0.9990934)-Metabolic pathways(K)(0.9978024)-Oxidative phosphorylation(K)(0.9968614)-Parkinson's disease(K)(0.9949334) 470 RRM1 11p15.4 0 0 0 2 166 24 1222 0.4129 0 0.168844221105528 Glutathione metabolism(K)(0.9971414)-Metablism of nucleotides(R)(0.9974772)-Metabolic pathways(K)(0.9989768)-Purine metabolism(K)(0.9972138)-Pyrimidine metabolism(K)(0.997448) 471 CREB1 2q33.3 0 0 2 0 84 23 1538 0.4152 1 0.0864321608040201 Androgen-mediated signaling(N)(0.9433086)-Antigen processing and presentation(K)(0.9952354)-BMP receptor signaling(N)(0.9945162)-EGFR1(C)(0.9985468)-FOXA transcription factor networks(N)(0.9585584)-Glypican pathway(N)(0.998041)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9996238)-Huntington's disease(K)(0.998858)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9970816)-IFN-gamma pathway(N)(0.9962146)-IL1-mediated signaling events(N)(0.9915626)-LPA receptor mediated events(N)(0.9884014)-Melanogenesis(K)(0.9941324)-Opioid Signalling(R)(0.9918422)-Plasma membrane estrogen receptor signaling(N)(0.9944844)-Prostate cancer(K)(0.9963188)-Signaling events regulated by Ret tyrosine kinase(N)(0.9865728)-Signalling by NGF(R)(0.9983306)-TNF receptor signaling pathway(N)(0.9982474)-VEGFR3 signaling in lymphatic endothelium(N)(0.990453)-Vasopressin-regulated water reabsorption(K)(0.9940742)-hypoxia-inducible factor in the cardivascular system(B)(0.9814932)-oxidative stress induced gene expression via nrf2(B)(0.9946704)-p38 mapk signaling pathway(B)(0.9871502)-p75(NTR)-mediated signaling(N)(0.998358) 472 ALDH3B1 11q13.2 0 2 21 1 72 23 1168 0.4152 0 0.0964824120603015 Drug metabolism - cytochrome P450(K)(0.9978458)-Histidine metabolism(K)(0.9979622)-Metabolic pathways(K)(0.9988672)-Metabolism of xenobiotics by cytochrome P450(K)(0.9979104) 473 KPNB1 17q21.32 0 0 3 0 153 23 1104 0.4152 0 0.15678391959799 Apoptosis(R)(0.9987114)-BMP receptor signaling(N)(0.9931748)-Endothelins(N)(0.9948772)-Glypican pathway(N)(0.9976548)-Host Interactions of HIV factors(R)(0.9968768)-IFN-gamma pathway(N)(0.9965356)-IL1-mediated signaling events(N)(0.9944078)-Influenza Life Cycle(R)(0.9992964)-Plasma membrane estrogen receptor signaling(N)(0.9978404)-TGFBR(C)(0.9983072)-TNF receptor signaling pathway(N)(0.996564)-TRAIL signaling pathway(N)(0.9841688)-role of ran in mitotic spindle regulation(B)(0.9822638) 474 PPARGC1A 4p15.2 0 0 0 2 153 23 1061 0.4152 0 0.155778894472362 Adipocytokine signaling pathway(K)(0.9968736)-BMP receptor signaling(N)(0.9957052)-Glypican pathway(N)(0.9969406)-Huntington's disease(K)(0.9972094)-IFN-gamma pathway(N)(0.9975316)-IL1-mediated signaling events(N)(0.9962722)-Insulin signaling pathway(K)(0.9990154)-Plasma membrane estrogen receptor signaling(N)(0.9963142)-Signaling events mediated by HDAC Class I(N)(0.998019)-TNF receptor signaling pathway(N)(0.9948484)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.992256)-regulation of pgc-1a(B)(0.9862094) 475 NUDT12 5q21.2 0 0 0 1 146 23 101 0.4152 0 0.147738693467337 Nicotinate and nicotinamide metabolism(K)(0.9984156)-Peroxisome(K)(0.9990688) 476 RPA2 1p35.3 0 0 0 2 233 23 276 0.4152 0 0.236180904522613 Cell Cycle Checkpoints(R)(0.9989342)-DNA Repair(R)(0.9989714)-DNA replication(K)(0.9884188)-G1/S Transition(R)(0.9956152)-Homologous recombination(K)(0.9973084)-Mismatch repair(K)(0.9960146)-Nucleotide excision repair(K)(0.9969842)-S Phase(R)(0.9948172)-Telomere Maintenance(R)(0.9988052) 477 MNX1 7q36.3 0 0 2 1 110 23 25 0.4152 0 0.11356783919598 Maturity onset diabetes of the young(K)(0.9978252) 478 ITGA10 1q21.1 0 0 20 2 7 23 527 0.4152 0 0.0291457286432161 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9963498)-Dilated cardiomyopathy(K)(0.9959166)-ECM-receptor interaction(K)(0.9975282)-Focal adhesion(K)(0.9984548)-Hypertrophic cardiomyopathy (HCM)(K)(0.9935154)-Integrin cell surface interactions(R)(0.9957886)-Integrin signalling pathway(P)(0.9982048)-Regulation of actin cytoskeleton(K)(0.9988318) 479 MYO5B 18q21.1 0 0 1 1 222 23 46 0.4152 0 0.225125628140704 Nicotinic acetylcholine receptor signaling pathway(P)(0.9991334) 480 OR8B8 11q24.2 0 0 0 11 359 23 389 0.4152 0 0.371859296482412 Olfactory transduction(K)(0.9987318) 481 POLG2 17q24.1 0 3 36 0 74 23 1120 0.4152 0 0.11356783919598 Metabolic pathways(K)(0.9992152) 482 LIPA 10q23.31 0 0 1 0 141 22 137 0.4152 0 0.142713567839196 Lysosome(K)(0.997805)-Steroid biosynthesis(K)(0.9968404) 483 PFN1 17p13.2 0 0 0 5 407 22 285 0.4152 0 0.414070351758794 Further platelet releasate(R)(0.9971164)-Regulation of actin cytoskeleton(K)(0.9988114)-Shigellosis(K)(0.9989654)-erk and pi-3 kinase are necessary for collagen binding in corneal epithelia(B)(0.9959176)-rho cell motility signaling pathway(B)(0.9984104) 484 PRKAR2A 3p21.31 0 0 0 1 200 22 731 0.4152 0 0.202010050251256 Apoptosis(K)(0.9983976)-Endothelin signaling pathway(P)(0.9977234)-Hedgehog signaling pathway(P)(0.996402)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9988704)-Insulin signaling pathway(K)(0.996889)-Opioid Signalling(R)(0.9986696)-Signalling by NGF(R)(0.9995572)-TGFBR(C)(0.9987156)-actions of nitric oxide in the heart(B)(0.9979406)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9948674)-akap95 role in mitosis and chromosome dynamics(B)(0.9955824)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9706018)-gata3 participate in activating the th2 cytokine genes expression(B)(0.9945248)-how progesterone initiates the oocyte maturation(B)(0.9922528)-mcalpain and friends in cell motility(B)(0.9937706)-nitric oxide signaling pathway(B)(0.9916922)-phospholipase c-epsilon pathway(B)(0.9865318)-protein kinase a at the centrosome(B)(0.9644802)-regulation of bad phosphorylation(B)(0.986593)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9908816)-repression of pain sensation by the transcriptional regulator dream(B)(0.974474)-rho-selective guanine exchange factor akap13 mediates stress fiber formation(B)(0.995194)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9963494)-transcription regulation by methyltransferase of carm1(B)(0.9883624) 485 RARA 17q21.2 0 18 27 1 166 22 370 0.4152 1 0.213065326633166 Acute myeloid leukemia(K)(0.995084)-Pathways in cancer(K)(0.9983148)-Retinoic acid receptors-mediated signaling(N)(0.9987628)-Vitamin D metabolism and pathway(P)(0.9975946) 486 PSMB1 6q27 0 0 1 4 200 22 450 0.4152 0 0.206030150753769 APC/C-mediated degradation of cell cycle proteins(R)(0.99575)-Apoptosis(R)(0.9993444)-Cell Cycle Checkpoints(R)(0.995584)-G1/S Transition(R)(0.9944538)-Host Interactions of HIV factors(R)(0.999089)-Metabolism of amino acids(R)(0.9980656)-Parkinson disease(P)(0.9986622)-Proteasome(K)(0.9191202)-S Phase(R)(0.9982396)-Signaling by Wnt(R)(0.9938104)-y branching of actin filaments(B)(0.9963284) 487 GZMA 5q11.2 0 0 1 0 125 22 392 0.4152 0 0.126633165829146 IL12-mediated signaling events(N)(0.9980338)-Neuroactive ligand-receptor interaction(K)(0.9989334)-granzyme a mediated apoptosis pathway(B)(0.9936958) 488 LIG4 13q33.3 0 0 1 7 243 22 166 0.4152 0 0.252261306532663 DNA Repair(R)(0.9979582)-HIV Life Cycle(R)(0.9980216)-Non-homologous end-joining(K)(0.9966746) 489 VAV2 9q34.2 0 0 3 1 163 22 1352 0.4152 0 0.167839195979899 B cell receptor signaling pathway(K)(0.9877758)-Chemokine signaling pathway(K)(0.9970606)-EGFR1(C)(0.999046)-EPO signaling pathway(N)(0.9050114)-Fc epsilon RI signaling pathway(K)(0.995008)-Fc gamma R-mediated phagocytosis(K)(0.998101)-Focal adhesion(K)(0.9991658)-Glypican pathway(N)(0.9977754)-KitReceptor(C)(0.9956314)-Leukocyte transendothelial migration(K)(0.9981796)-Natural killer cell mediated cytotoxicity(K)(0.9981848)-Nectin adhesion pathway(N)(0.9955928)-Regulation of actin cytoskeleton(K)(0.9983658)-Signaling by Rho GTPases(R)(0.9989302)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9964142)-T cell receptor signaling pathway(K)(0.995059)-TRAIL signaling pathway(N)(0.9878948)-phosphoinositides and their downstream targets(B)(0.993203) 490 SEPSECS 4p15.2 0 0 0 2 158 22 41 0.4152 0 0.160804020100503 Aminoacyl-tRNA biosynthesis(K)(0.9992648) 491 EIF4A1 17p13.1 0 0 0 7 409 22 833 0.4152 0 0.418090452261307 Endothelins(N)(0.9977926)-Glypican pathway(N)(0.9984886)-IFN-gamma pathway(N)(0.9984406)-Metabolism of proteins(R)(0.9981282)-TRAIL signaling pathway(N)(0.9982572)-internal ribosome entry pathway(B)(0.9963388)-regulation of eif-4e and p70s6 kinase(B)(0.9784848) 492 TARSL2 15q26.3 0 2 5 5 113 22 41 0.4152 0 0.125628140703518 Aminoacyl-tRNA biosynthesis(K)(0.9982366) 493 PGM1 1p31.3 0 1 3 1 141 22 1322 0.4152 0 0.146733668341709 Amino sugar and nucleotide sugar metabolism(K)(0.9979568)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9970794)-Metabolic pathways(K)(0.9987568)-Metabolism of carbohydrates(R)(0.9985288)-Pentose phosphate pathway(K)(0.9905692)-Purine metabolism(K)(0.9982924)-Starch and sucrose metabolism(K)(0.998735) 494 CA4 17q23.1 0 13 38 0 76 22 40 0.4152 0 0.127638190954774 Nitrogen metabolism(K)(0.9949932)-Proximal tubule bicarbonate reclamation(K)(0.998424) 495 MAPK7 17p11.2 0 1 5 5 328 22 730 0.4152 0 0.34070351758794 Alzheimer disease-amyloid secretase pathway(P)(0.9977222)-EGFR1(C)(0.9989786)-Gap junction(K)(0.9979502)-GnRH signaling pathway(K)(0.9941406)-Interleukin signaling pathway(P)(0.9971808)-MAPK signaling pathway(K)(0.9987146)-Neurotrophin signaling pathway(K)(0.9992466)-Parkinson disease(P)(0.9975246)-Signalling by NGF(R)(0.9994264)-p75(NTR)-mediated signaling(N)(0.9975808) 496 CCKAR 4p15.2 0 0 0 3 165 22 531 0.4152 0 0.168844221105528 Calcium signaling pathway(K)(0.9986904)-Class A/1 (Rhodopsin-like receptors)(R)(0.9994238)-Neuroactive ligand-receptor interaction(K)(0.9978294)-Pancreatic secretion(K)(0.9968024) 497 KISS1R 19p13.3 0 0 3 1 202 22 351 0.4152 0 0.207035175879397 Class A/1 (Rhodopsin-like receptors)(R)(0.9978766)-Neuroactive ligand-receptor interaction(K)(0.999484) 498 POLR1D 13q12.2 0 1 4 1 236 21 1506 0.4152 0 0.24321608040201 Cytosolic DNA-sensing pathway(K)(0.998844)-Metabolic pathways(K)(0.999684)-Purine metabolism(K)(0.9982098)-Pyrimidine metabolism(K)(0.9934906)-TNF alpha/NF-kB(C)(0.9971234)-Transcription(R)(0.9993524)-carm1 and regulation of the estrogen receptor(B)(0.9948506)-nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells(B)(0.9851686)-the information processing pathway at the ifn beta enhancer(B)(0.9972532)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9932028) 499 NR1D1 17q21.1 0 35 33 1 156 21 59 0.4152 0 0.226130653266332 Circadian rhythm - mammal(K)(0.9969328)-Circadian rhythm pathway(N)(0.995232)-NR transcription pathway(R)(0.9983156) 500 PLA2G3 22q12.2 0 0 3 1 276 21 1602 0.4152 0 0.281407035175879 Arachidonic acid metabolism(K)(0.9942764)-Fc epsilon RI signaling pathway(K)(0.9972642)-Glycerophospholipid metabolism(K)(0.9968212)-GnRH signaling pathway(K)(0.9969044)-Long-term depression(K)(0.9972488)-MAPK signaling pathway(K)(0.9984042)-Metabolic pathways(K)(0.9991788)-Pancreatic secretion(K)(0.9982158)-VEGF signaling pathway(K)(0.9966792)-Vascular smooth muscle contraction(K)(0.997958) 501 NOTCH3 19p13.12 0 2 8 0 83 21 236 0.4152 0 0.0934673366834171 Alzheimer disease-presenilin pathway(P)(0.9990732)-Dorso-ventral axis formation(K)(0.9973976)-Generic Transcription Pathway(R)(0.994354)-NOTCH(C)(0.9984518)-Notch signaling pathway(K)(0.9959942)-Notch signaling pathway(P)(0.9791222) 502 NEGR1 1p31.1 0 1 0 12 185 21 135 0.4152 0 0.198994974874372 Cell adhesion molecules (CAMs)(K)(0.9985406) 503 ITGA8 10p13 0 0 5 1 78 21 636 0.4152 0 0.0844221105527638 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9964666)-Cell adhesion molecules (CAMs)(K)(0.999131)-Dilated cardiomyopathy(K)(0.9984522)-ECM-receptor interaction(K)(0.9957032)-Focal adhesion(K)(0.997115)-Hypertrophic cardiomyopathy (HCM)(K)(0.9848782)-Integrin cell surface interactions(R)(0.995612)-Integrin signalling pathway(P)(0.9981898)-Regulation of actin cytoskeleton(K)(0.9986764) 504 E2F4 16q22.1 0 0 1 10 483 21 323 0.4152 0 0.496482412060302 Cell cycle(K)(0.9980762)-Regulation of retinoblastoma protein(N)(0.9966222)-TGF-beta signaling pathway(K)(0.9984176)-TGFBR(C)(0.9982886)-mets affect on macrophage differentiation(B)(0.9962644) 505 B3GALT6 1p36.33 0 0 2 2 181 21 1139 0.4152 0 0.185929648241206 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.996661)-Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.998035)-Metabolic pathways(K)(0.9989056) 506 CAV1 7q31.2 0 0 0 0 86 21 1569 0.4152 0 0.0864321608040201 AndrogenReceptor(C)(0.9978948)-Bacterial invasion of epithelial cells(K)(0.98806)-Cell surface interactions at the vascular wall(R)(0.9973066)-EGFR1(C)(0.9992126)-Endocytosis(K)(0.9992874)-Focal adhesion(K)(0.9969488)-Glypican pathway(N)(0.9970384)-IFN-gamma pathway(N)(0.9918966)-Integrin signalling pathway(P)(0.998399)-Metabolism of lipids and lipoproteins(R)(0.9985278)-Metabolism of nitric oxide(R)(0.9825006)-Plasma membrane estrogen receptor signaling(N)(0.9946334)-Proteogylcan syndecan-mediated signaling events(N)(0.997407)-Signaling events mediated by PTP1B(N)(0.9960358)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9924744)-TGFBR(C)(0.9977192)-TNF alpha/NF-kB(C)(0.9978874)-TNF receptor signaling pathway(N)(0.999189)-Viral myocarditis(K)(0.9961756)-actions of nitric oxide in the heart(B)(0.9959096)-corticosteroids and cardioprotection(B)(0.9720242)-integrin signaling pathway(B)(0.983627)-ion channels and their functional role in vascular endothelium(B)(0.9931362) 507 GSTZ1 14q24.3 0 0 3 1 180 21 1173 0.4152 0 0.184924623115578 Drug metabolism - cytochrome P450(K)(0.9976802)-Glutathione metabolism(K)(0.9973126)-Metabolic pathways(K)(0.998933)-Metabolism of xenobiotics by cytochrome P450(K)(0.9971678)-Tyrosine metabolism(K)(0.9979548) 508 GUCA1C 3q13.13 0 0 2 0 41 21 416 0.4152 0 0.04321608040201 Olfactory transduction(K)(0.9983734)-Phototransduction(K)(0.997932)-Visual signal transduction: Cones(N)(0.9826892) 509 ABCA10 17q24.3 0 3 21 0 74 21 44 0.4152 0 0.0984924623115578 ABC transporters(K)(0.9983548) 510 FGFR1 8p12 0 41 44 9 156 21 1123 0.4152 1 0.251256281407035 Adherens junction(K)(0.995727)-Angiogenesis(P)(0.9963292)-FGF signaling pathway(P)(0.9939684)-Glypican pathway(N)(0.9969078)-MAPK signaling pathway(K)(0.9981356)-Pathways in cancer(K)(0.995103)-Prostate cancer(K)(0.9957724)-Proteogylcan syndecan-mediated signaling events(N)(0.9985276)-Regulation of actin cytoskeleton(K)(0.9993782) 511 DDX6 11q23.3 0 0 1 11 349 21 59 0.4152 1 0.362814070351759 RNA degradation(K)(0.999426) 512 SYVN1 11q13.1 0 0 3 1 117 21 285 0.4152 0 0.121608040201005 Protein processing in endoplasmic reticulum(K)(0.9976714)-Ubiquitin mediated proteolysis(K)(0.998127) 513 PRPF8 17p13.3 0 0 1 9 419 21 232 0.4152 0 0.431155778894472 Formation and Maturation of mRNA Transcript(R)(0.9990642)-Spliceosome(K)(0.9967696) 514 RASGRF2 5q14.1 0 0 1 1 147 21 384 0.4152 0 0.149748743718593 MAPK signaling pathway(K)(0.9990786)-Signaling by Rho GTPases(R)(0.9977186) 515 GJA3 13q12.11 0 0 0 4 244 20 20 0.4179 0 0.249246231155779 Gap junction trafficking and regulation(R)(0.9994062) 516 NR2E1 6q21 0 2 7 7 230 20 30 0.4179 0 0.247236180904523 NR transcription pathway(R)(0.9972746) 517 WNT5A 3p14.3 0 0 0 0 170 20 1206 0.4179 0 0.170854271356784 Alzheimer disease-presenilin pathway(P)(0.9983028)-Angiogenesis(P)(0.9954962)-Glypican pathway(N)(0.9954114)-Hedgehog signaling pathway(K)(0.9955164)-Melanogenesis(K)(0.9934358)-Pathways in cancer(K)(0.9987722)-Proteogylcan syndecan-mediated signaling events(N)(0.998538)-Wnt signaling pathway(K)(0.9968178)-Wnt signaling pathway(P)(0.998299)-Wnt(C)(0.9970094) 518 FANCA 16q24.3 0 0 1 13 474 20 36 0.4179 1 0.490452261306533 BARD1 signaling events(N)(0.9984188)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9992038) 519 MTMR6 13q12.13 0 0 3 3 240 20 1131 0.4179 0 0.247236180904523 Fructose and mannose metabolism(K)(0.9970684)-Metabolic pathways(K)(0.998568)-Riboflavin metabolism(K)(0.9974604) 520 LAMA5 20q13.33 0 3 23 0 31 20 814 0.4179 0 0.057286432160804 Amoebiasis(K)(0.9991176)-ECM-receptor interaction(K)(0.996508)-Focal adhesion(K)(0.9980418)-Integrin cell surface interactions(R)(0.9981826)-Integrin signalling pathway(P)(0.9991224)-Pathways in cancer(K)(0.9989772)-Proteogylcan syndecan-mediated signaling events(N)(0.9980392)-a6b1 and a6b4 Integrin signaling(N)(0.9951168)-agrin in postsynaptic differentiation(B)(0.9960016)-prion pathway(B)(0.9961366) 521 IDO2 8p11.21 0 13 42 11 167 20 1126 0.4179 0 0.234170854271357 Metabolic pathways(K)(0.9992366)-Tryptophan metabolism(K)(0.9978842) 522 TRPC6 11q22.1 0 0 5 11 328 20 206 0.4179 0 0.34572864321608 Endothelins(N)(0.9989498)-ion channels and their functional role in vascular endothelium(B)(0.9989112) 523 ATG5 6q21 0 3 12 6 225 20 138 0.4179 0 0.247236180904523 RIG-I-like receptor signaling pathway(K)(0.998439)-Regulation of autophagy(K)(0.9981718)-Shigellosis(K)(0.998078) 524 ACOX2 3p14.3 0 0 0 0 162 20 1261 0.4179 0 0.162814070351759 Metabolic pathways(K)(0.9992182)-Metabolism of lipids and lipoproteins(R)(0.9989038)-PPAR signaling pathway(K)(0.9966028)-Peroxisome(K)(0.9982996)-Primary bile acid biosynthesis(K)(0.9982026) 525 MAP4K1 19q13.2 0 0 4 1 82 20 888 0.4179 0 0.0874371859296482 Glypican pathway(N)(0.9985794)-MAPK signaling pathway(K)(0.9991472)-Proteogylcan syndecan-mediated signaling events(N)(0.9982106)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9975126)-TCR signaling in naive CD4+ T cells(N)(0.9969424)-TRAIL signaling pathway(N)(0.9979834)-mapkinase signaling pathway(B)(0.9963444) 526 CTSB 8p23.1 0 0 2 26 342 20 195 0.4179 0 0.371859296482412 Antigen processing and presentation(K)(0.9978672)-Lysosome(K)(0.9986472) 527 WNT8A 5q31.2 0 0 0 2 133 20 720 0.4179 0 0.135678391959799 Alzheimer disease-presenilin pathway(P)(0.998849)-Hedgehog signaling pathway(K)(0.9980764)-Melanogenesis(K)(0.9984678)-Pathways in cancer(K)(0.9994678)-Wnt signaling pathway(K)(0.9982062)-Wnt signaling pathway(P)(0.9982422) 528 OR4K2 14q11.2 0 0 1 0 56 20 413 0.4179 0 0.057286432160804 Olfactory transduction(K)(0.9988194) 529 IL20RA 6q23.3 0 1 1 4 196 20 363 0.4179 0 0.203015075376884 Cytokine-cytokine receptor interaction(K)(0.9989706)-Interleukin signaling pathway(P)(0.9993758)-Jak-STAT signaling pathway(K)(0.9989018) 530 BSG 19p13.3 0 0 3 2 205 19 503 0.4211 0 0.21105527638191 Cell surface interactions at the vascular wall(R)(0.9968848)-Integrin cell surface interactions(R)(0.9976214)-Metabolism of carbohydrates(R)(0.9993498)-Proteogylcan syndecan-mediated signaling events(N)(0.9993394)-Pyruvate metabolism and TCA cycle(R)(0.9932788) 531 STX5 11q12.3 0 0 6 2 129 19 40 0.4211 0 0.137688442211055 Botulinum neurotoxicity(R)(0.9941082)-SNARE interactions in vesicular transport(K)(0.9990366) 532 RELA 11q13.1 0 0 5 2 91 19 1910 0.4211 0 0.0984924623115578 Adipocytokine signaling pathway(K)(0.998249)-Amoebiasis(K)(0.9982716)-AndrogenReceptor(C)(0.9958332)-Angiopoietin receptor Tie2-mediated signaling(N)(0.992481)-Apoptosis(K)(0.9876042)-B cell receptor signaling pathway(K)(0.9888266)-Chagas disease(K)(0.9962866)-Chemokine signaling pathway(K)(0.9988376)-Cytosolic DNA-sensing pathway(K)(0.9960046)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.996852)-Fc-epsilon receptor I signaling in mast cells(N)(0.9848098)-Glypican pathway(N)(0.995242)-IL1-mediated signaling events(N)(0.9694156)-IL12-mediated signaling events(N)(0.9964526)-IL2-mediated signaling events(N)(0.9960096)-IL23-mediated signaling events(N)(0.9823028)-Integrins in angiogenesis(N)(0.995871)-LPA receptor mediated events(N)(0.9793676)-Leishmaniasis(K)(0.9860238)-MAPK signaling pathway(K)(0.9984232)-NOD-like receptor signaling pathway(K)(0.9925586)-NOTCH(C)(0.9966574)-Neurotrophin signaling pathway(K)(0.9798874)-Pathways in cancer(K)(0.9978914)-Prostate cancer(K)(0.986392)-RIG-I-like receptor signaling pathway(K)(0.9949358)-Shigellosis(K)(0.9951)-Signaling by Aurora kinases(N)(0.9857514)-Signaling events mediated by HDAC Class I(N)(0.9971806)-Signaling events regulated by Ret tyrosine kinase(N)(0.988648)-Signalling by NGF(R)(0.9975818)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9936366)-T cell receptor signaling pathway(K)(0.9810068)-TCR signaling in naive CD4+ T cells(N)(0.9888806)-TNF alpha/NF-kB(C)(0.9991018)-TNF receptor signaling pathway(N)(0.9909182)-Toll-like receptor signaling pathway(K)(0.9954528)-bone remodeling(B)(0.9032236)-corticosteroids and cardioprotection(B)(0.9782264)-double stranded rna induced gene expression(B)(0.9697622)-erythropoietin mediated neuroprotection through nf-kb(B)(0.9527928)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9524608)-keratinocyte differentiation(B)(0.9714076)-lectin induced complement pathway(B)(0.9808732)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9928644)-p75(NTR)-mediated signaling(N)(0.9953604)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9742396)-t cell receptor signaling pathway(B)(0.9792174)-the information processing pathway at the ifn beta enhancer(B)(0.9913144)-trefoil factors initiate mucosal healing(B)(0.9360278) 533 SEC11A 15q25.3 0 1 2 0 124 19 61 0.4211 0 0.127638190954774 Insulin Synthesis and Secretion(R)(0.9989832)-Protein export(K)(0.997581)-Vasopressin synthesis(P)(0.9965046) 534 AGTR2 23q23 0 0 1 7 168 19 488 0.4211 0 0.176884422110553 Class A/1 (Rhodopsin-like receptors)(R)(0.9992252)-Neuroactive ligand-receptor interaction(K)(0.9980288)-Receptor-ligand complexes bind G proteins(R)(0.9985716)-Renin-angiotensin system(K)(0.9955678)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9960046)-bioactive peptide induced signaling pathway(B)(0.9947212)-chrebp regulation by carbohydrates and camp(B)(0.9940278)-ion channels and their functional role in vascular endothelium(B)(0.9987874)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.995576)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9842316)-ß-arrestins in gpcr desensitization(B)(0.9908108) 535 PIPOX 17q11.2 0 5 23 0 132 19 1198 0.4211 0 0.160804020100503 Glycine, serine and threonine metabolism(K)(0.996336)-Lysine degradation(K)(0.9972788)-Metabolic pathways(K)(0.9989146)-Peroxisome(K)(0.9983622) 536 IL11RA 9p13.3 0 0 4 0 174 19 419 0.4211 0 0.178894472361809 Cytokine-cytokine receptor interaction(K)(0.9976914)-Hematopoietic cell lineage(K)(0.9990082)-Interleukin signaling pathway(P)(0.9983248)-Jak-STAT signaling pathway(K)(0.9973246) 537 GYPB NA 0 0 0 1 119 19 51 0.4211 0 0.120603015075377 Malaria(K)(0.9984948) 538 CDH15 16q24.3 0 0 2 13 490 19 428 0.4211 0 0.507537688442211 Cell adhesion molecules (CAMs)(K)(0.997852)-Wnt signaling pathway(P)(0.9989444) 539 PARD3 10p11.21 0 0 1 3 99 19 896 0.4211 0 0.103517587939698 Adherens junction(K)(0.997393)-Chemokine signaling pathway(K)(0.9982002)-Endocytosis(K)(0.9984002)-Neuroactive ligand-receptor interaction(K)(0.9997896)-TGFBR(C)(0.9979736)-Tight junction(K)(0.9950056) 540 NEDD4L 18q21.31 0 0 3 1 204 19 908 0.4211 0 0.209045226130653 Aldosterone-regulated sodium reabsorption(K)(0.9969106)-Endocytosis(K)(0.998451)-Glypican pathway(N)(0.9977)-IFN-gamma pathway(N)(0.997454)-Ubiquitin mediated proteolysis(K)(0.99802)-p75(NTR)-mediated signaling(N)(0.997837) 541 CDH23 10q22.1 0 0 10 1 127 19 299 0.4211 0 0.138693467336683 Wnt signaling pathway(P)(0.9982098) 542 PDE4D 5q12.1 0 0 2 3 153 19 223 0.4211 0 0.158793969849246 Opioid Signalling(R)(0.9987314)-Purine metabolism(K)(0.9985702) 543 GABRR1 6q15 0 0 0 5 259 19 272 0.4211 0 0.265326633165829 Neuroactive ligand-receptor interaction(K)(0.9996804) 544 OR7C1 19p13.12 0 0 5 1 116 19 389 0.4211 0 0.122613065326633 Olfactory transduction(K)(0.998418) 545 HMGB1 13q12.3 0 0 6 4 232 18 101 0.4218 0 0.24321608040201 Base excision repair(K)(0.997806)-amb2 Integrin signaling(N)(0.9991152)-the information processing pathway at the ifn beta enhancer(B)(0.9969292) 546 SH3GL2 9p22.2 0 0 4 4 206 18 493 0.4218 0 0.215075376884422 EGFR1(C)(0.9992228)-Endocytosis(K)(0.9990682)-Membrane Trafficking(R)(0.998261)-Signaling by EGFR(R)(0.9973324)-Signalling by NGF(R)(0.998927) 547 TP73 1p36.32 0 0 0 2 228 18 469 0.4218 0 0.231155778894472 Alpha6Beta4Integrin(C)(0.9971936)-Huntington disease(P)(0.998757)-Neurotrophin signaling pathway(K)(0.998186)-TGFBR(C)(0.9974738)-atm signaling pathway(B)(0.9979768)-p53 pathway by glucose deprivation(P)(0.9968184)-p53 pathway(P)(0.9966254)-p53 signaling pathway(K)(0.9976198) 548 PICALM 11q14.2 0 2 6 5 253 18 13 0.4218 1 0.267336683417085 endocytotic role of ndk phosphins and dynamin(B)(0.9982468) 549 PSEN1 14q24.2 0 0 0 2 196 18 891 0.4218 0 0.198994974874372 Alzheimer disease-amyloid secretase pathway(P)(0.997173)-Alzheimer disease-presenilin pathway(P)(0.9988242)-Alzheimer's disease(K)(0.9986148)-NOTCH(C)(0.995013)-Neurotrophin signaling pathway(K)(0.9971602)-Notch signaling pathway(K)(0.9939666)-Presenilin action in Notch and Wnt signaling(N)(0.9821328)-Proteogylcan syndecan-mediated signaling events(N)(0.9987206)-Signalling by NGF(R)(0.9977302)-Wnt signaling pathway(K)(0.9991336)-g-secretase mediated erbb4 signaling pathway(B)(0.9931184)-p75(NTR)-mediated signaling(N)(0.9990746)-segmentation clock(B)(0.9804856) 550 CTBP1 4p16.3 0 1 1 1 130 18 1074 0.4218 0 0.133668341708543 Chronic myeloid leukemia(K)(0.9951988)-Glypican pathway(N)(0.9989602)-IFN-gamma pathway(N)(0.9970446)-Notch signaling pathway(K)(0.9975174)-Pathways in cancer(K)(0.999022)-Regulation of retinoblastoma protein(N)(0.9945794)-Wnt signaling pathway(K)(0.997388)-Wnt signaling pathway(P)(0.9975722)-Wnt(C)(0.9984358) 551 EGFR 7p11.2 0 3 5 1 47 18 1700 0.4218 1 0.0562814070351759 Adherens junction(K)(0.9941354)-Alpha6Beta4Integrin(C)(0.9943166)-Calcium signaling pathway(K)(0.9985638)-Cytokine-cytokine receptor interaction(K)(0.9991952)-Dorso-ventral axis formation(K)(0.9961684)-EGF receptor signaling pathway(P)(0.98825)-EGFR1(C)(0.997225)-Endocytosis(K)(0.9982958)-Endothelins(N)(0.9934526)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9985262)-ErbB signaling pathway(K)(0.986063)-Focal adhesion(K)(0.9944042)-Gap junction(K)(0.9958228)-GnRH signaling pathway(K)(0.990885)-LPA receptor mediated events(N)(0.9944284)-MAPK signaling pathway(K)(0.9979814)-Pathways in cancer(K)(0.9987466)-Plasma membrane estrogen receptor signaling(N)(0.9916736)-Prostate cancer(K)(0.9915532)-Proteogylcan syndecan-mediated signaling events(N)(0.994675)-Regulation of Telomerase(N)(0.997042)-Regulation of actin cytoskeleton(K)(0.997248)-Signaling by EGFR(R)(0.9827058)-Signaling events mediated by PTP1B(N)(0.989657)-Thromboxane A2 receptor signaling(N)(0.9838316)-a6b1 and a6b4 Integrin signaling(N)(0.9583316)-role of erbb2 in signal transduction and oncology(B)(0.9804018) 552 ALPL 1p36.12 0 0 2 2 244 18 1258 0.4218 0 0.249246231155779 Metabolic pathways(K)(0.9989218)-TNF alpha/NF-kB(C)(0.9993598)-regulators of bone mineralization(B)(0.99758) 553 LDHD 16q23.1 0 0 1 8 496 18 40 0.4218 0 0.507537688442211 Pyruvate metabolism(K)(0.9993078) 554 HMOX1 22q12.3 0 0 1 2 270 18 144 0.4218 0 0.274371859296482 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.998157)-Porphyrin and chlorophyll metabolism(K)(0.9968132)-il-10 anti-inflammatory signaling pathway(B)(0.9974992)-oxidative stress induced gene expression via nrf2(B)(0.996812) 555 CAMKK1 17p13.2 0 0 0 6 411 18 130 0.4218 0 0.419095477386935 Adipocytokine signaling pathway(K)(0.9973262)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.996518)-nfat and hypertrophy of the heart (B)(0.9980652)-regulation of pgc-1a(B)(0.9983654) 556 FUCA2 6q24.2 0 0 3 1 197 18 16 0.4218 0 0.202010050251256 Other glycan degradation(K)(0.9989888) 557 SRPR 11q24.2 0 0 0 14 343 18 56 0.4218 0 0.358793969849246 Insulin Synthesis and Secretion(R)(0.9997078)-Protein export(K)(0.9970024) 558 ARFGEF2 20q13.13 0 5 20 0 36 18 248 0.4218 0 0.0613065326633166 Metabolism of proteins(R)(0.9994234)-adp-ribosylation factor(B)(0.9975638)-thrombin signaling and protease-activated receptors(B)(0.9986442) 559 ASH1L 1q22 0 0 28 0 12 18 176 0.4218 0 0.0402010050251256 Lysine degradation(K)(0.9988316)-Tight junction(K)(0.9980586) 560 NTN1 17p13.1 0 0 1 11 459 18 129 0.4218 0 0.473366834170854 Axon guidance(K)(0.9982154) 561 BCL9 1q21.1 0 3 23 1 5 18 346 0.4218 1 0.0321608040201005 Wnt signaling pathway(P)(0.9992564)-Wnt(C)(0.9949782) 562 CALML6 1p36.33 0 0 0 2 197 18 1205 0.4218 0 0.2 Alzheimer's disease(K)(0.9980086)-Calcium signaling pathway(K)(0.9990992)-Gastric acid secretion(K)(0.996626)-Glioma(K)(0.9891702)-GnRH signaling pathway(K)(0.9960856)-Insulin signaling pathway(K)(0.997308)-Long-term potentiation(K)(0.9862232)-Melanogenesis(K)(0.9943842)-Neurotrophin signaling pathway(K)(0.9979378)-Olfactory transduction(K)(0.9962412)-Oocyte meiosis(K)(0.9948806)-Phosphatidylinositol signaling system(K)(0.995946)-Phototransduction(K)(0.9941546)-Salivary secretion(K)(0.9954724)-Vascular smooth muscle contraction(K)(0.998101) 563 CCR6 6q27 0 0 1 3 210 18 602 0.4218 0 0.215075376884422 Chemokine signaling pathway(K)(0.9990614)-Class A/1 (Rhodopsin-like receptors)(R)(0.9967604)-Cytokine-cytokine receptor interaction(K)(0.9987316)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.998559)-Receptor-ligand complexes bind G proteins(R)(0.997288) 564 CDH20 18q21.33 0 0 2 1 205 18 299 0.4218 0 0.209045226130653 Wnt signaling pathway(P)(0.9972754) 565 DDO 6q21 0 0 2 4 223 17 108 0.4269 0 0.230150753768844 Alanine, aspartate and glutamate metabolism(K)(0.9971108)-Peroxisome(K)(0.9995146) 566 HMHA1 19p13.3 0 0 2 1 193 17 125 0.4269 0 0.196984924623116 Signaling by Rho GTPases(R)(0.9983392) 567 CHEK2 22q12.1 0 0 2 4 292 17 276 0.4269 1 0.299497487437186 Cell Cycle Checkpoints(R)(0.9980808)-Cell cycle(K)(0.99953)-FOXM1 transcription factor network(N)(0.994256)-p53 pathway(P)(0.992205)-p53 signaling pathway(K)(0.9977148) 568 NEU3 11q13.4 0 9 16 4 122 17 51 0.4269 0 0.151758793969849 Other glycan degradation(K)(0.9978622)-Sphingolipid metabolism(K)(0.9984196) 569 SKI 1p36.33 0 0 1 2 207 17 666 0.4269 0 0.21105527638191 BMP receptor signaling(N)(0.995447)-Glypican pathway(N)(0.9973526)-Hedgehog(C)(0.996334)-IFN-gamma pathway(N)(0.9987472)-Signaling by BMP(R)(0.985367)-TGF-beta signaling pathway(P)(0.998305)-TGFBR(C)(0.9982588) 570 RAD51 15q15.1 0 0 1 6 188 17 450 0.4269 0 0.195979899497487 BARD1 signaling events(N)(0.998357)-DNA Repair(R)(0.998772)-Homologous recombination(K)(0.9978884)-Pathways in cancer(K)(0.9996306)-atm signaling pathway(B)(0.9949342)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9974466) 571 PRKCA 17q24.2 0 8 21 1 87 17 2422 0.4269 0 0.117587939698492 Aldosterone-regulated sodium reabsorption(K)(0.9851644)-Alpha6Beta4Integrin(C)(0.9877174)-Alzheimer disease-amyloid secretase pathway(P)(0.9933994)-Amoebiasis(K)(0.9929122)-Apoptosis signaling pathway(P)(0.9769534)-BMP receptor signaling(N)(0.9951568)-Calcium signaling pathway(K)(0.9988802)-EGF receptor signaling pathway(P)(0.8270252)-EGFR1(C)(0.9958968)-Endothelins(N)(0.9472904)-ErbB signaling pathway(K)(0.9828828)-Fc epsilon RI signaling pathway(K)(0.9445764)-Fc gamma R-mediated phagocytosis(K)(0.9961386)-Focal adhesion(K)(0.9973204)-Formation of Platelet plug(R)(0.9978204)-Gastric acid secretion(K)(0.995881)-Glypican pathway(N)(0.987856)-GnRH signaling pathway(K)(0.9886884)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9963596)-IFN-gamma pathway(N)(0.9937912)-IL1-mediated signaling events(N)(0.9839466)-IL12-mediated signaling events(N)(0.9916164)-IL2-mediated signaling events(N)(0.990019)-IL23-mediated signaling events(N)(0.9852142)-KitReceptor(C)(0.9784164)-LPA receptor mediated events(N)(0.9834048)-Leukocyte transendothelial migration(K)(0.9929864)-Long-term depression(K)(0.9836244)-MAPK signaling pathway(K)(0.9976594)-Melanogenesis(K)(0.9733382)-Natural killer cell mediated cytotoxicity(K)(0.998296)-Pancreatic secretion(K)(0.9958154)-Pathogenic Escherichia coli infection(K)(0.993198)-Pathways in cancer(K)(0.999311)-Phosphatidylinositol signaling system(K)(0.9952326)-Plasma membrane estrogen receptor signaling(N)(0.9582206)-Proteogylcan syndecan-mediated signaling events(N)(0.9969758)-Retinoic acid receptors-mediated signaling(N)(0.9922502)-Salivary secretion(K)(0.9968458)-Signaling by Aurora kinases(N)(0.9792528)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9867888)-Signaling events regulated by Ret tyrosine kinase(N)(0.9841718)-TCR signaling in naive CD4+ T cells(N)(0.9708284)-TNF receptor signaling pathway(N)(0.9832894)-Thromboxane A2 receptor signaling(N)(0.9744844)-Tight junction(K)(0.9984268)-Vascular smooth muscle contraction(K)(0.995741)-Vibrio cholerae infection(K)(0.9951528)-Wnt signaling pathway(K)(0.9927932)-Wnt signaling pathway(P)(0.9962886)-Wnt(C)(0.997165)-a6b1 and a6b4 Integrin signaling(N)(0.8779698)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9450004)-keratinocyte differentiation(B)(0.9570666)-oxidative stress induced gene expression via nrf2(B)(0.9922924)-p75(NTR)-mediated signaling(N)(0.9979368)-regulation of eif-4e and p70s6 kinase(B)(0.9192786)-tpo signaling pathway(B)(0.9421274) 572 HMGCR 5q13.3 0 0 1 1 154 17 1187 0.4269 0 0.15678391959799 Metabolic pathways(K)(0.9990202)-Metabolism of lipids and lipoproteins(R)(0.999096)-Terpenoid backbone biosynthesis(K)(0.9968956) 573 ACVR2B 3p22.2 0 0 0 0 141 17 380 0.4269 0 0.141708542713568 Cytokine-cytokine receptor interaction(K)(0.998231)-Signaling by BMP(R)(0.9964576)-TGF-beta signaling pathway(K)(0.9977482)-TGF-beta signaling pathway(P)(0.9987342) 574 SERPINF2 17p13.3 0 0 0 10 422 17 169 0.4269 0 0.434170854271357 Complement and coagulation cascades(K)(0.9983512)-Formation of Platelet plug(R)(0.9992052) 575 CARS 11p15.4 0 0 1 0 182 17 41 0.4269 1 0.18391959798995 Aminoacyl-tRNA biosynthesis(K)(0.9985316) 576 PSMD8 19q13.2 0 0 5 1 76 17 392 0.4269 0 0.0824120603015075 APC/C-mediated degradation of cell cycle proteins(R)(0.9914728)-Apoptosis(R)(0.9985892)-Cell Cycle Checkpoints(R)(0.9970918)-G1/S Transition(R)(0.993463)-Host Interactions of HIV factors(R)(0.999306)-Metabolism of amino acids(R)(0.9992352)-Proteasome(K)(0.9875002)-S Phase(R)(0.9911176)-Signaling by Wnt(R)(0.9962554) 577 NUPL1 13q12.13 0 0 3 3 238 17 429 0.4269 0 0.245226130653266 HIV Life Cycle(R)(0.996192)-Host Interactions of HIV factors(R)(0.996599)-Influenza Life Cycle(R)(0.9987884)-Metabolism of carbohydrates(R)(0.9993626)-Metabolism of non-coding RNA(R)(0.9932252)-Transport of Mature Transcript to Cytoplasm(R)(0.9971614) 578 CTSS 1q21.2 0 4 21 0 12 17 311 0.4269 0 0.0371859296482412 Antigen processing and presentation(K)(0.9986624)-Lysosome(K)(0.999069)-Phagosome(K)(0.9964828) 579 DNASE2B 1p31.1 0 0 0 1 164 17 121 0.4269 0 0.165829145728643 Lysosome(K)(0.9993552) 580 OR6Y1 1q23.1 0 0 20 0 7 17 389 0.4269 0 0.0271356783919598 Olfactory transduction(K)(0.9987882) 581 SEC61A2 10p14 0 2 8 0 79 16 377 0.4303 0 0.0894472361809045 Insulin Synthesis and Secretion(R)(0.9955408)-Phagosome(K)(0.9993206)-Protein export(K)(0.99613)-Protein processing in endoplasmic reticulum(K)(0.9989896)-Vibrio cholerae infection(K)(0.996051) 582 RNGTT 6q15 0 0 1 4 268 16 244 0.4303 0 0.274371859296482 Formation and Maturation of mRNA Transcript(R)(0.999239)-HIV Life Cycle(R)(0.9984602)-Transcription(R)(0.998804)-mRNA Processing(R)(0.9970812) 583 C5 9q33.2 0 0 0 1 146 16 505 0.4303 0 0.147738693467337 Class A/1 (Rhodopsin-like receptors)(R)(0.9980552)-Complement and coagulation cascades(K)(0.996339)-Innate Immunity Signaling(R)(0.9957808)-Prion diseases(K)(0.9990178)-Receptor-ligand complexes bind G proteins(R)(0.9982276)-Systemic lupus erythematosus(K)(0.9984136) 584 ALDOB 9q31.1 0 0 0 1 165 16 1281 0.4303 0 0.166834170854271 FOXA transcription factor networks(N)(0.984239)-Glucose Regulation of Insulin Secretion(R)(0.9990278)-Metabolic pathways(K)(0.9986738)-Metabolism of carbohydrates(R)(0.9989794)-Pentose phosphate pathway(K)(0.9820962) 585 CCNE1 19q12 0 6 7 1 65 16 877 0.4303 1 0.0793969849246231 AndrogenReceptor(C)(0.9986982)-BARD1 signaling events(N)(0.9958498)-Cell Cycle Checkpoints(R)(0.9919994)-Cell cycle(K)(0.9860732)-FOXM1 transcription factor network(N)(0.994109)-G1/S Transition(R)(0.986677)-ID(C)(0.9950002)-Oocyte meiosis(K)(0.9967608)-Parkinson disease(P)(0.9950296)-Pathways in cancer(K)(0.9988052)-Prostate cancer(K)(0.99577)-Regulation of retinoblastoma protein(N)(0.9979846)-S Phase(R)(0.8984394)-Signaling events mediated by PRL(N)(0.9943928)-TGFBR(C)(0.9976184)-il-2 receptor beta chain in t cell activation(B)(0.9955588)-p53 signaling pathway(K)(0.997175) 586 WARS2 1p12 0 0 5 0 100 16 82 0.4303 0 0.105527638190955 Aminoacyl-tRNA biosynthesis(K)(0.9981586)-Tryptophan metabolism(K)(0.998473)-tRNA Aminoacylation(R)(0.9967788) 587 CDH22 20q13.12 0 0 12 0 29 16 299 0.4303 0 0.0412060301507538 Wnt signaling pathway(P)(0.9992928) 588 DCTN3 9p13.3 0 0 4 0 174 16 98 0.4303 0 0.178894472361809 G2/M Transition(R)(0.9986428)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9976052) 589 MTHFD1 14q23.2 0 1 1 1 181 16 1133 0.4303 0 0.184924623115578 Metabolic pathways(K)(0.9984564)-Metabolism of vitamins and cofactors(R)(0.9981564)-One carbon pool by folate(K)(0.9981196) 590 PLOD1 1p36.22 0 0 0 1 237 16 44 0.4303 0 0.239195979899497 Lysine degradation(K)(0.999199) 591 ATP5J 21q21.3 0 1 3 3 75 16 1393 0.4303 0 0.0824120603015075 Alzheimer's disease(K)(0.998867)-FOXA transcription factor networks(N)(0.9862074)-Glucose Regulation of Insulin Secretion(R)(0.9967366)-Huntington's disease(K)(0.998225)-Metablism of nucleotides(R)(0.9948706)-Metabolic pathways(K)(0.9987026)-Oxidative phosphorylation(K)(0.9963036)-Parkinson's disease(K)(0.9980672) 592 ST3GAL4 11q24.2 0 0 1 13 339 16 1122 0.4303 0 0.354773869346734 Metabolic pathways(K)(0.9994312) 593 STX7 6q23.2 0 0 4 0 191 16 284 0.4303 0 0.195979899497487 Botulinum neurotoxicity(R)(0.9010384)-Membrane Trafficking(R)(0.9972486)-Parkinson disease(P)(0.997961)-Phagosome(K)(0.998775)-SNARE interactions in vesicular transport(K)(0.9964434) 594 RAB5A 3p24.3 0 0 0 0 120 16 1171 0.4303 0 0.120603015075377 Amoebiasis(K)(0.9983378)-Amyotrophic lateral sclerosis (ALS)(K)(0.990749)-BMP receptor signaling(N)(0.997433)-EGFR1(C)(0.9986312)-Endocytosis(K)(0.9988606)-Glypican pathway(N)(0.9977418)-IFN-gamma pathway(N)(0.9946516)-IL1-mediated signaling events(N)(0.9909646)-Phagosome(K)(0.9986984)-Plasma membrane estrogen receptor signaling(N)(0.9927458)-TNF receptor signaling pathway(N)(0.997473)-Vasopressin-regulated water reabsorption(K)(0.9958924)-phosphoinositides and their downstream targets(B)(0.9866798) 595 CD226 18q22.2 0 1 1 1 201 16 220 0.4303 0 0.205025125628141 Cell adhesion molecules (CAMs)(K)(0.9990644)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9988996) 596 MED13 17q23.2 0 12 24 0 107 16 33 0.4303 0 0.143718592964824 Generic Transcription Pathway(R)(0.9990466) 597 APPBP2 17q23.2 0 20 39 0 99 16 125 0.4303 0 0.158793969849246 Androgen-mediated signaling(N)(0.990591) 598 ITPR3 6p21.31 0 0 5 0 79 16 1177 0.4303 0 0.0844221105527638 Alzheimer's disease(K)(0.9953092)-B cell activation(P)(0.9642946)-Calcium signaling pathway(K)(0.9983336)-Endothelin signaling pathway(P)(0.9823878)-Gap junction(K)(0.9989702)-Gastric acid secretion(K)(0.9922154)-GnRH signaling pathway(K)(0.9902446)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9978324)-Long-term depression(K)(0.9856106)-Long-term potentiation(K)(0.9679638)-Oocyte meiosis(K)(0.9981836)-Opioid Signalling(R)(0.9927516)-Pancreatic secretion(K)(0.9985004)-Phosphatidylinositol signaling system(K)(0.9968284)-Salivary secretion(K)(0.9925606)-Signalling by NGF(R)(0.9982566)-Taste transduction(K)(0.9966332)-Vascular smooth muscle contraction(K)(0.9962664)-Wnt signaling pathway(P)(0.9972302) 599 GSTM5 1p13.3 0 0 1 0 153 16 145 0.4303 0 0.154773869346734 Biological oxidations(R)(0.9972806)-Drug metabolism - cytochrome P450(K)(0.9946448)-Glutathione metabolism(K)(0.998238)-Metabolism of xenobiotics by cytochrome P450(K)(0.9995534) 600 CTNS 17p13.3 0 0 0 9 415 16 121 0.4303 0 0.426130653266332 Lysosome(K)(0.9989) 601 EIF2S3 23p22.11 0 0 1 9 183 15 232 0.4329 0 0.193969849246231 Metabolism of proteins(R)(0.9985476)-double stranded rna induced gene expression(B)(0.998425)-eukaryotic protein translation(B)(0.9933364)-regulation of eif2(B)(0.9967498)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9990802) 602 LAMB1 7q31.1 0 0 1 2 98 15 665 0.4329 0 0.101507537688442 Amoebiasis(K)(0.9980602)-ECM-receptor interaction(K)(0.9967876)-Focal adhesion(K)(0.9975402)-Integrin cell surface interactions(R)(0.9969698)-Integrin signalling pathway(P)(0.9984388)-Pathways in cancer(K)(0.9986612)-a6b1 and a6b4 Integrin signaling(N)(0.9959748)-agrin in postsynaptic differentiation(B)(0.9976768)-prion pathway(B)(0.9935818) 603 CDC2 10q21.2 0 0 2 0 104 15 489 0.4329 0 0.106532663316583 APC/C-mediated degradation of cell cycle proteins(R)(0.9837408)-AndrogenReceptor(C)(0.9985464)-Cell Cycle Checkpoints(R)(0.997748)-FOXM1 transcription factor network(N)(0.995954)-G1/S Transition(R)(0.9977184)-G2/M Transition(R)(0.9968664)-Hedgehog(C)(0.987811)-Retinoic acid receptors-mediated signaling(N)(0.9978038)-TGFBR(C)(0.9984454)-Wnt(C)(0.998187)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.9909918) 604 AR 23q12 0 2 2 4 136 15 1028 0.4329 0 0.144723618090452 Alpha6Beta4Integrin(C)(0.99582)-Androgen-mediated signaling(N)(0.979998)-AndrogenReceptor(C)(0.9959768)-FOXA transcription factor networks(N)(0.9841036)-Glypican pathway(N)(0.9980242)-IFN-gamma pathway(N)(0.9935338)-Oocyte meiosis(K)(0.9996924)-Pathways in cancer(K)(0.9985622)-Prostate cancer(K)(0.9946388)-TGFBR(C)(0.9967428) 605 OR2F2 7q35 0 0 1 0 79 15 413 0.4329 0 0.0804020100502513 Olfactory transduction(K)(0.9990474) 606 WASF2 1p36.11 0 0 0 2 227 15 420 0.4329 0 0.230150753768844 Adherens junction(K)(0.9980668)-Bacterial invasion of epithelial cells(K)(0.9971714)-Fc gamma R-mediated phagocytosis(K)(0.99768)-Nectin adhesion pathway(N)(0.9982944)-Regulation of actin cytoskeleton(K)(0.9992476)-Shigellosis(K)(0.9978514)-y branching of actin filaments(B)(0.9965558) 607 STX1A 7q11.23 0 0 5 1 66 15 282 0.4329 0 0.0723618090452261 Glucose Regulation of Insulin Secretion(R)(0.9988148)-Insulin Synthesis and Secretion(R)(0.9986)-Metabotropic glutamate receptor group II pathway(P)(0.9944628)-Metabotropic glutamate receptor group III pathway(P)(0.9965728)-SNARE interactions in vesicular transport(K)(0.9969964)-Synaptic Transmission(R)(0.997404) 608 IL2RG 23q13.1 0 0 1 8 171 15 914 0.4329 0 0.180904522613065 Cytokine-cytokine receptor interaction(K)(0.9981132)-Endocytosis(K)(0.9983542)-IFN-gamma pathway(N)(0.998373)-IL12-mediated signaling events(N)(0.9979778)-IL2-mediated signaling events(N)(0.9965774)-Jak-STAT signaling pathway(K)(0.9986272)-Primary immunodeficiency(K)(0.9984474)-TCR signaling in naive CD8+ T cells(N)(0.9982456)-il-2 receptor beta chain in t cell activation(B)(0.9958216) 609 CTTN 11q13.3 0 16 75 0 57 15 553 0.4329 0 0.148743718592965 Bacterial invasion of epithelial cells(K)(0.9972702)-Nectin adhesion pathway(N)(0.9965614)-Pathogenic Escherichia coli infection(K)(0.9971636)-Proteogylcan syndecan-mediated signaling events(N)(0.998102)-Shigellosis(K)(0.9987664)-Tight junction(K)(0.9984102)-agrin in postsynaptic differentiation(B)(0.9973978) 610 TREH 11q23.3 0 0 1 11 350 15 53 0.4329 0 0.363819095477387 Starch and sucrose metabolism(K)(0.9993252) 611 GTF2A2 15q22.2 0 0 0 0 164 15 254 0.4329 0 0.164824120603015 Basal transcription factors(K)(0.993749)-Formation and Maturation of mRNA Transcript(R)(0.9981766)-HIV Life Cycle(R)(0.9983796)-Transcription(R)(0.9994212) 612 FDFT1 8p23.1 0 0 1 26 340 15 1123 0.4329 0 0.368844221105528 Metabolic pathways(K)(0.9990598)-Steroid biosynthesis(K)(0.998597) 613 TUBB2C 9q34.3 0 0 5 0 136 15 629 0.4329 0 0.141708542713568 G2/M Transition(R)(0.9992658)-Gap junction(K)(0.9967786)-Huntington disease(P)(0.9994978)-Metabolism of proteins(R)(0.9977258)-Pathogenic Escherichia coli infection(K)(0.9980526)-Phagosome(K)(0.9983484) 614 CYSLTR2 13q14.2 0 0 0 10 292 15 538 0.4329 0 0.303517587939699 Calcium signaling pathway(K)(0.9982334)-Endothelins(N)(0.996804)-Neuroactive ligand-receptor interaction(K)(0.996888)-eicosanoid metabolism(B)(0.9988098) 615 TAS2R42 12p13.2 0 1 3 3 95 15 52 0.4329 0 0.10251256281407 Taste transduction(K)(0.9994372) 616 CDC34 19p13.3 0 0 3 3 206 15 265 0.4329 0 0.213065326633166 TNF alpha/NF-kB(C)(0.9986874)-Ubiquitin mediated proteolysis(K)(0.9988358) 617 MYO7A 11q13.5 0 20 44 5 113 15 46 0.4329 0 0.182914572864322 Nicotinic acetylcholine receptor signaling pathway(P)(0.9991268) 618 PECAM1 17q23.3 0 4 35 0 76 15 433 0.4329 0 0.115577889447236 Cell adhesion molecules (CAMs)(K)(0.9991932)-Cell surface interactions at the vascular wall(R)(0.998817)-Formation of Platelet plug(R)(0.9979954)-Integrin cell surface interactions(R)(0.9975112)-Leukocyte transendothelial migration(K)(0.9992366)-Malaria(K)(0.9939594) 619 THBS4 5q14.1 0 0 0 1 147 15 559 0.4329 0 0.148743718592965 ECM-receptor interaction(K)(0.9948778)-Focal adhesion(K)(0.9985364)-Formation of Platelet plug(R)(0.9987572)-Malaria(K)(0.9971526)-Phagosome(K)(0.9977904)-Signaling by PDGF(R)(0.9970964)-TGF-beta signaling pathway(K)(0.9977484) 620 OR51A7 11p15.4 0 0 0 0 181 15 413 0.4329 0 0.181909547738693 Olfactory transduction(K)(0.9977272) 621 CCT6A 7p11.2 0 1 2 2 73 15 201 0.4329 0 0.078391959798995 Metabolism of proteins(R)(0.9988956) 622 PCDH15 10q21.1 0 0 3 6 150 15 299 0.4329 0 0.159798994974874 Wnt signaling pathway(P)(0.9995228) 623 CYP27A1 2q35 0 0 1 1 85 14 1251 0.439 0 0.0874371859296482 Biological oxidations(R)(0.9988624)-Metabolic pathways(K)(0.9979714)-Metabolism of lipids and lipoproteins(R)(0.997472)-PPAR signaling pathway(K)(0.998595)-Primary bile acid biosynthesis(K)(0.9969442)-Vitamin D metabolism and pathway(P)(0.9968772) 624 HNF4G 8q21.11 0 2 55 2 35 14 34 0.439 0 0.0944723618090452 Maturity onset diabetes of the young(K)(0.9957992)-Regulation of beta-cell development(R)(0.9981496) 625 TFDP1 13q34 0 0 4 7 247 14 481 0.439 0 0.25929648241206 Apoptosis(R)(0.996942)-Cell cycle(K)(0.998727)-G1/S Transition(R)(0.9969976)-Regulation of retinoblastoma protein(N)(0.9960726)-TGF-beta signaling pathway(K)(0.9984838)-TGFBR(C)(0.997826)-il-2 receptor beta chain in t cell activation(B)(0.9972618)-influence of ras and rho proteins on g1 to s transition(B)(0.9948872) 626 CHST11 12q23.3 0 0 2 0 81 14 32 0.439 0 0.0834170854271357 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9962864)-Sulfur metabolism(K)(0.9984176) 627 GUCA1A 6p21.1 0 0 2 1 93 14 418 0.439 0 0.0964824120603015 Olfactory transduction(K)(0.9983526)-Visual signal transduction: Cones(N)(0.997557)-visual signal transduction(B)(0.9839052) 628 GNAQ 9q21.2 0 1 1 1 151 14 1632 0.439 1 0.154773869346734 Alzheimer's disease(K)(0.9931382)-Amoebiasis(K)(0.997052)-Calcium signaling pathway(K)(0.9975544)-Chagas disease(K)(0.9968948)-Endothelin signaling pathway(P)(0.9713352)-Endothelins(N)(0.9930436)-Formation of Platelet plug(R)(0.9986978)-Gap junction(K)(0.9955)-Gastric acid secretion(K)(0.9944414)-GnRH signaling pathway(K)(0.9896406)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.996699)-Huntington's disease(K)(0.999479)-LPA receptor mediated events(N)(0.993546)-Long-term depression(K)(0.9894644)-Long-term potentiation(K)(0.9857078)-Melanogenesis(K)(0.991405)-Opioid Signalling(R)(0.990421)-Pancreatic secretion(K)(0.9977676)-Plasma membrane estrogen receptor signaling(N)(0.9975758)-Proteogylcan syndecan-mediated signaling events(N)(0.9978122)-Receptor-ligand complexes bind G proteins(R)(0.9936998)-Salivary secretion(K)(0.9982758)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9957412)-Thromboxane A2 receptor signaling(N)(0.98419)-Vascular smooth muscle contraction(K)(0.996888)-Wnt signaling pathway(P)(0.998649)-actions of nitric oxide in the heart(B)(0.9938034)-ccr3 signaling in eosinophils(B)(0.8836424)-effects of calcineurin in keratinocyte differentiation(B)(0.9678382)-g-protein signaling through tubby proteins(B)(0.9552346)-pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase(B)(0.9910072)-thrombin signaling and protease-activated receptors(B)(0.9850208) 629 UPB1 22q11.23 0 0 2 1 255 14 1138 0.439 0 0.25929648241206 Drug metabolism - other enzymes(K)(0.962852)-Metabolic pathways(K)(0.998516)-Pantothenate and CoA biosynthesis(K)(0.968115)-Pyrimidine metabolism(K)(0.998621) 630 HDAC4 2q37.3 0 0 1 3 154 14 100 0.439 0 0.158793969849246 Signaling events mediated by HDAC Class I(N)(0.9986404) 631 ACADM 1p31.1 0 0 1 1 177 14 1279 0.439 0 0.179899497487437 FOXA transcription factor networks(N)(0.9830058)-Metabolic pathways(K)(0.998458)-Metabolism of lipids and lipoproteins(R)(0.9989296)-PPAR signaling pathway(K)(0.9979786) 632 MAN2C1 15q24.2 0 0 0 2 140 14 26 0.439 0 0.142713567839196 Other glycan degradation(K)(0.999099)-er associated degradation (erad) pathway(B)(0.9972996) 633 PAFAH1B2 11q23.3 0 0 0 14 365 14 1145 0.439 1 0.380904522613065 Ether lipid metabolism(K)(0.973169)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9978302)-Metabolic pathways(K)(0.9984508) 634 CAMK2D 4q26 0 0 0 1 121 14 1324 0.439 0 0.122613065326633 Calcium signaling pathway(K)(0.9987812)-ErbB signaling pathway(K)(0.9969756)-Gastric acid secretion(K)(0.997067)-Glioma(K)(0.9856248)-GnRH signaling pathway(K)(0.9976224)-IFN-gamma pathway(N)(0.9965034)-Long-term potentiation(K)(0.9841536)-Melanogenesis(K)(0.9937346)-Neurotrophin signaling pathway(K)(0.9977996)-Olfactory transduction(K)(0.9988574)-Oocyte meiosis(K)(0.9975156)-TGFBR(C)(0.9982616)-Wnt signaling pathway(K)(0.998184)-Wnt(C)(0.9957554)-bioactive peptide induced signaling pathway(B)(0.9899186)-regulation of pgc-1a(B)(0.9923584)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.989589) 635 ABCA1 9q31.1 0 0 0 2 169 14 189 0.439 0 0.171859296482412 ABC transporters(K)(0.9982546)-Metabolism of lipids and lipoproteins(R)(0.9987464)-Retinoic acid receptors-mediated signaling(N)(0.9980492) 636 PIGL 17p11.2 0 0 3 13 418 14 1123 0.439 0 0.436180904522613 Metabolic pathways(K)(0.9993726) 637 SEC23A 14q21.1 0 0 2 0 127 14 198 0.439 0 0.12964824120603 Membrane Trafficking(R)(0.9944356)-Protein processing in endoplasmic reticulum(K)(0.9993742) 638 PPP6C 9q33.3 0 0 2 0 155 14 423 0.439 0 0.157788944723618 TNF alpha/NF-kB(C)(0.9991548)-Wnt signaling pathway(P)(0.998916) 639 PSMB10 16q22.1 0 0 1 10 454 14 437 0.439 0 0.467336683417085 APC/C-mediated degradation of cell cycle proteins(R)(0.9914656)-Apoptosis(R)(0.9996156)-Cell Cycle Checkpoints(R)(0.9977678)-G1/S Transition(R)(0.9940828)-Host Interactions of HIV factors(R)(0.9971942)-Metabolism of amino acids(R)(0.9987226)-Parkinson disease(P)(0.9977506)-Proteasome(K)(0.8864378)-S Phase(R)(0.9940226)-Signaling by Wnt(R)(0.9944676) 640 EXOSC9 4q27 0 0 1 0 107 14 59 0.439 0 0.108542713567839 RNA degradation(K)(0.998287) 641 STAR 8p12 0 38 39 9 164 14 106 0.439 0 0.251256281407035 Metabolism of lipids and lipoproteins(R)(0.9985406) 642 OPHN1 23q12 0 2 2 7 152 14 125 0.439 0 0.163819095477387 Signaling by Rho GTPases(R)(0.9991816) 643 NUP214 9q34.13 0 0 1 0 153 13 1062 0.4425 1 0.154773869346734 BMP receptor signaling(N)(0.9957802)-Glypican pathway(N)(0.9978038)-HIV Life Cycle(R)(0.9971024)-Host Interactions of HIV factors(R)(0.996946)-IFN-gamma pathway(N)(0.998755)-Influenza Life Cycle(R)(0.9980616)-Metabolism of carbohydrates(R)(0.9968908)-Metabolism of non-coding RNA(R)(0.9964072)-Signaling events mediated by HDAC Class I(N)(0.9960366)-TGFBR(C)(0.9988572)-Transport of Mature Transcript to Cytoplasm(R)(0.9950568)-mechanism of protein import into the nucleus(B)(0.9814212) 644 GNAS NA 0 7 27 0 13 13 1504 0.4425 1 0.0472361809045226 Amoebiasis(K)(0.9987678)-Calcium signaling pathway(K)(0.9989792)-Chagas disease(K)(0.9968832)-Endothelin signaling pathway(P)(0.9851992)-Endothelins(N)(0.9406682)-Gap junction(K)(0.9942254)-Gastric acid secretion(K)(0.9959008)-Glypican pathway(N)(0.9990266)-GnRH signaling pathway(K)(0.98844)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9945944)-LPA receptor mediated events(N)(0.9918892)-Long-term depression(K)(0.9930868)-Melanogenesis(K)(0.9944806)-PNAT(P)(0.9917772)-Pancreatic secretion(K)(0.9960936)-Plasma membrane estrogen receptor signaling(N)(0.9930952)-Proteogylcan syndecan-mediated signaling events(N)(0.9972552)-Receptor-ligand complexes bind G proteins(R)(0.9969664)-Salivary secretion(K)(0.9936692)-Taste transduction(K)(0.9960112)-Vascular smooth muscle contraction(K)(0.9987966)-Vasopressin-regulated water reabsorption(K)(0.9964694)-Vibrio cholerae infection(K)(0.9969166)-ccr3 signaling in eosinophils(B)(0.936381)-corticosteroids and cardioprotection(B)(0.9704872)-gata3 participate in activating the th2 cytokine genes expression(B)(0.9688866)-how progesterone initiates the oocyte maturation(B)(0.9898556)-ion channels and their functional role in vascular endothelium(B)(0.9953104)-phospholipase c-epsilon pathway(B)(0.9738388)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9890944)-regulation of spermatogenesis by crem(B)(0.9745716)-ß-arrestins in gpcr desensitization(B)(0.9635938) 645 PPAP2A 5q11.2 0 0 2 3 134 13 1228 0.4425 0 0.139698492462312 Ether lipid metabolism(K)(0.9792372)-Fc gamma R-mediated phagocytosis(K)(0.9989046)-Glycerophospholipid metabolism(K)(0.9979976)-Metabolic pathways(K)(0.9991922)-Sphingolipid metabolism(K)(0.996914) 646 DNA2 10q21.3 0 0 0 2 170 13 145 0.4425 0 0.17286432160804 DNA Replication(R)(0.9980522)-DNA replication(K)(0.998436)-S Phase(R)(0.9987702)-Telomere Maintenance(R)(0.9994666) 647 CASP9 1p36.21 0 0 0 2 225 13 1435 0.4425 0 0.228140703517588 Alzheimer's disease(K)(0.9992008)-Amyotrophic lateral sclerosis (ALS)(K)(0.9941596)-Angiogenesis(P)(0.9947676)-Apoptosis signaling pathway(P)(0.9057984)-Apoptosis(K)(0.9973102)-Apoptosis(R)(0.9980088)-EGFR1(C)(0.9983248)-FAS signaling pathway(P)(0.992693)-Glypican pathway(N)(0.9968604)-Huntington's disease(K)(0.9970216)-Parkinson's disease(K)(0.9963602)-Pathways in cancer(K)(0.9988418)-Prostate cancer(K)(0.988931)-Signalling by NGF(R)(0.9989116)-TNF receptor signaling pathway(N)(0.9954584)-VEGF signaling pathway(K)(0.994121)-Viral myocarditis(K)(0.9963932)-internal ribosome entry pathway(B)(0.9865894)-p53 signaling pathway(K)(0.9976438)-p75(NTR)-mediated signaling(N)(0.9979734)-trefoil factors initiate mucosal healing(B)(0.9749566) 648 TMLHE 23q28 0 0 3 11 145 13 44 0.4425 0 0.159798994974874 Lysine degradation(K)(0.9985734) 649 FGG 4q32.1 0 1 1 1 114 13 272 0.4425 0 0.117587939698492 Complement and coagulation cascades(K)(0.9974324)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9951308)-Formation of Platelet plug(R)(0.9976064)-IL6-mediated signaling events(N)(0.9971502)-Integrin cell surface interactions(R)(0.9975794)-Plasminogen activating cascade(P)(0.953922) 650 LPAR2 19p13.11 0 0 9 1 76 13 368 0.4425 0 0.0864321608040201 LPA receptor mediated events(N)(0.9965574)-Neuroactive ligand-receptor interaction(K)(0.99849)-rho-selective guanine exchange factor akap13 mediates stress fiber formation(B)(0.9970328) 651 CASP8 2q33.1 0 0 3 0 76 13 1467 0.4425 0 0.0793969849246231 Alzheimer's disease(K)(0.997722)-Androgen-mediated signaling(N)(0.9495132)-Apoptosis signaling pathway(P)(0.9688976)-Apoptosis(K)(0.9927508)-Apoptosis(R)(0.9955494)-Chagas disease(K)(0.9970056)-FAS signaling pathway (CD95)(N)(0.9906092)-FAS signaling pathway(P)(0.9855606)-Huntington disease(P)(0.9982762)-Huntington's disease(K)(0.9980754)-Integrins in angiogenesis(N)(0.9982204)-NOD-like receptor signaling pathway(K)(0.9955344)-Pathways in cancer(K)(0.9987672)-RIG-I-like receptor signaling pathway(K)(0.994756)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9959024)-TNF alpha/NF-kB(C)(0.9978652)-TNF receptor signaling pathway(N)(0.9989762)-TRAIL signaling pathway(N)(0.9812548)-Toll-like receptor signaling pathway(K)(0.9940156)-Viral myocarditis(K)(0.9939056)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9797536)-internal ribosome entry pathway(B)(0.9759616)-p53 signaling pathway(K)(0.9981566) 652 KCNQ5 6q13 0 1 0 3 241 13 43 0.4425 0 0.246231155778894 ion channels and their functional role in vascular endothelium(B)(0.9990778) 653 CCNA2 4q27 0 0 1 0 107 13 489 0.4425 0 0.108542713567839 APC/C-mediated degradation of cell cycle proteins(R)(0.9931862)-Cell cycle(K)(0.9985778)-DNA Replication(R)(0.973767)-G1/S Transition(R)(0.983234)-G2/M Transition(R)(0.999128)-ID(C)(0.9967216)-IL2-mediated signaling events(N)(0.9970342)-Progesterone-mediated oocyte maturation(K)(0.998011)-Regulation of retinoblastoma protein(N)(0.9969078)-Signaling events mediated by PRL(N)(0.9940686) 654 PLCB1 20p12.3 0 0 3 0 63 13 2605 0.4425 0 0.0663316582914573 Alzheimer's disease(K)(0.9942996)-Amoebiasis(K)(0.9969212)-Calcium signaling pathway(K)(0.9988636)-Chagas disease(K)(0.9969382)-Chemokine signaling pathway(K)(0.9979804)-Endothelin signaling pathway(P)(0.9756586)-Endothelins(N)(0.9900838)-Formation of Platelet plug(R)(0.9983876)-Gap junction(K)(0.998274)-Gastric acid secretion(K)(0.9945202)-GnRH signaling pathway(K)(0.9960024)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9959124)-Huntington's disease(K)(0.9980454)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9968442)-Inositol phosphate metabolism(K)(0.9858496)-Long-term depression(K)(0.9912252)-Long-term potentiation(K)(0.9892956)-Metabolic pathways(K)(0.9984692)-Opioid Signalling(R)(0.9955646)-Pancreatic secretion(K)(0.9966628)-Plasma membrane estrogen receptor signaling(N)(0.996595)-Salivary secretion(K)(0.9959476)-Vascular smooth muscle contraction(K)(0.9950514)-Wnt signaling pathway(K)(0.99899)-Wnt signaling pathway(P)(0.997793)-actions of nitric oxide in the heart(B)(0.993683)-bcr signaling pathway(B)(0.9894192)-effects of calcineurin in keratinocyte differentiation(B)(0.9712806)-eicosanoid metabolism(B)(0.8187086)-epo signaling pathway(B)(0.8137346)-erk and pi-3 kinase are necessary for collagen binding in corneal epithelia(B)(0.9667858)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9729158)-growth hormone signaling pathway(B)(0.9837832)-phosphoinositides and their downstream targets(B)(0.9868202)-rho cell motility signaling pathway(B)(0.8667872)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9460854)-thrombin signaling and protease-activated receptors(B)(0.9922648)-tpo signaling pathway(B)(0.9643018)-vegf hypoxia and angiogenesis(B)(0.906726) 655 TNNT3 11p15.5 0 0 1 0 183 13 31 0.4425 0 0.184924623115578 Muscle contraction(R)(0.9995498) 656 MLLT4 6q27 0 0 1 5 205 13 413 0.4425 1 0.212060301507538 Adherens junction(K)(0.9985074)-Alzheimer disease-presenilin pathway(P)(0.9989012)-Leukocyte transendothelial migration(K)(0.9972312)-Nectin adhesion pathway(N)(0.9967892)-Tight junction(K)(0.9993474) 657 GATA4 8p23.1 0 0 1 29 348 13 59 0.4425 0 0.379899497487437 alk in cardiac myocytes(B)(0.9983958)-nfat and hypertrophy of the heart (B)(0.997851) 658 NT5E 6q14.3 0 0 1 4 250 13 1263 0.4425 0 0.256281407035176 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9978204)-Metablism of nucleotides(R)(0.9983106)-Metabolic pathways(K)(0.9983094)-Nicotinate and nicotinamide metabolism(K)(0.8933256)-Purine metabolism(K)(0.9973366)-Pyrimidine metabolism(K)(0.9985424) 659 BHMT 5q14.1 0 0 0 3 160 13 1126 0.4425 0 0.163819095477387 Glycine, serine and threonine metabolism(K)(0.9974328)-Metabolic pathways(K)(0.9966854) 660 AKT3 1q44 0 0 23 0 15 13 1811 0.4425 0 0.0381909547738693 Adipocytokine signaling pathway(K)(0.9971672)-Apoptosis(K)(0.9866634)-B cell receptor signaling pathway(K)(0.9905166)-Chagas disease(K)(0.9920688)-Chemokine signaling pathway(K)(0.9938452)-EGF receptor signaling pathway(P)(0.9892812)-Endothelin signaling pathway(P)(0.989454)-ErbB signaling pathway(K)(0.978269)-FAS signaling pathway(P)(0.986033)-FGF signaling pathway(P)(0.9898578)-Fc gamma R-mediated phagocytosis(K)(0.9983042)-Focal adhesion(K)(0.9978034)-Glypican pathway(N)(0.9957676)-Huntington disease(P)(0.9993554)-Hypoxia response via HIF activation(P)(0.9022808)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9949162)-Insulin signaling pathway(K)(0.9977354)-Jak-STAT signaling pathway(K)(0.996588)-MAPK signaling pathway(K)(0.997415)-Neurotrophin signaling pathway(K)(0.9838254)-Pathways in cancer(K)(0.99917)-Progesterone-mediated oocyte maturation(K)(0.998484)-Prostate cancer(K)(0.9903228)-Regulation of beta-cell development(R)(0.9853068)-Signalling by NGF(R)(0.9970896)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9952612)-TRAIL signaling pathway(N)(0.9810462)-Tight junction(K)(0.9985098)-Toll-like receptor signaling pathway(K)(0.9965996)-mTOR signaling pathway(K)(0.9928164)-p53 pathway(P)(0.9892132) 661 DGAT2 11q13.5 0 10 33 4 116 13 1132 0.4425 0 0.163819095477387 Glycerolipid metabolism(K)(0.9674078)-Metabolic pathways(K)(0.9986122)-Retinol metabolism(K)(0.9993548) 662 EPHA5 4q13.1 0 0 1 1 102 13 151 0.4425 0 0.104522613065327 Axon guidance(K)(0.9986046)-EphrinA-EPHA pathway(N)(0.9905194) 663 AGAP1 2q37.2 0 0 1 2 128 13 204 0.4425 0 0.131658291457286 Endocytosis(K)(0.9991288) 664 PRCP 11q14.1 0 1 8 6 236 13 32 0.4425 0 0.252261306532663 Formation of Fibrin Clot (Clotting Cascade)(R)(0.9992032) 665 TAS2R16 7q31.32 0 0 1 0 97 13 52 0.4425 0 0.0984924623115578 Taste transduction(K)(0.9961852) 666 PHKA2 23p22.13 0 0 3 6 154 13 491 0.4425 0 0.163819095477387 Calcium signaling pathway(K)(0.998793)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9992152)-Insulin signaling pathway(K)(0.998499)-Metabolism of carbohydrates(R)(0.9971742) 667 GRIK4 11q23.3 0 0 1 12 351 13 395 0.4425 0 0.365829145728643 Huntington disease(P)(0.997259)-Neuroactive ligand-receptor interaction(K)(0.9989506) 668 OR6B2 2q37.3 0 0 0 2 116 13 389 0.4425 0 0.118592964824121 Olfactory transduction(K)(0.9990318) 669 THBS2 6q27 0 0 1 3 206 12 559 0.4481 0 0.21105527638191 ECM-receptor interaction(K)(0.9966552)-Focal adhesion(K)(0.9987532)-Formation of Platelet plug(R)(0.996197)-Malaria(K)(0.9970592)-Phagosome(K)(0.997179)-Signaling by PDGF(R)(0.9974264)-TGF-beta signaling pathway(K)(0.9992194) 670 ZDHHC21 9p22.3 0 0 3 5 192 12 11 0.4481 0 0.201005025125628 Metabolism of nitric oxide(R)(0.9992872) 671 TNFRSF11A 18q21.33 0 0 3 1 193 12 403 0.4481 0 0.197989949748744 Cytokine-cytokine receptor interaction(K)(0.9980248)-TNF alpha/NF-kB(C)(0.9986686)-bone remodeling(B)(0.995564) 672 THOP1 19p13.3 0 0 2 2 167 12 17 0.4481 0 0.171859296482412 Renin-angiotensin system(K)(0.9987898) 673 MED4 13q14.2 0 0 0 12 296 12 33 0.4481 0 0.309547738693467 Generic Transcription Pathway(R)(0.9991354) 674 XRCC4 5q14.2 0 0 1 1 152 12 166 0.4481 0 0.154773869346734 DNA Repair(R)(0.9953834)-HIV Life Cycle(R)(0.9992222)-Non-homologous end-joining(K)(0.9964116) 675 HSD17B12 11p11.2 0 0 3 1 88 12 1147 0.4481 0 0.0924623115577889 Biosynthesis of unsaturated fatty acids(K)(0.9975978)-Metabolic pathways(K)(0.99948)-Steroid hormone biosynthesis(K)(0.9952608) 676 GNG12 1p31.3 0 0 0 1 148 12 1081 0.4481 0 0.149748743718593 Chemokine signaling pathway(K)(0.9982352)-Formation of Platelet plug(R)(0.9979846)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9958492)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9983228)-Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction(P)(0.9944064)-MAPK signaling pathway(K)(0.9985582)-Opioid Signalling(R)(0.9983288)-Receptor-ligand complexes bind G proteins(R)(0.9965678)-Regulation of actin cytoskeleton(K)(0.9988394)-Wnt signaling pathway(P)(0.998208) 677 SRP68 17q25.1 0 3 16 0 86 12 56 0.4481 0 0.105527638190955 Insulin Synthesis and Secretion(R)(0.9988552)-Protein export(K)(0.9957086) 678 CCNT1 12q13.11 0 0 1 0 55 12 320 0.4481 0 0.0562814070351759 Formation and Maturation of mRNA Transcript(R)(0.9980072)-HIV Life Cycle(R)(0.9966286)-Host Interactions of HIV factors(R)(0.9982278)-Transcription(R)(0.9984308) 679 CLCA1 1p22.3 0 0 0 2 169 12 486 0.4481 0 0.171859296482412 Olfactory transduction(K)(0.9968266)-Pancreatic secretion(K)(0.9962864) 680 HES5 1p36.32 0 0 0 2 213 12 53 0.4481 0 0.21608040201005 Notch signaling pathway(K)(0.99922)-Notch signaling pathway(P)(0.9990244) 681 IGFBP4 17q21.2 0 6 30 2 170 12 17 0.4481 0 0.209045226130653 Regulation of IGF Activity by IGFBP(R)(0.9992492) 682 CA6 1p36.23 0 0 0 2 245 12 23 0.4481 0 0.248241206030151 Nitrogen metabolism(K)(0.9986166) 683 NEIL3 4q34.3 0 0 0 4 134 12 34 0.4481 0 0.138693467336683 Base excision repair(K)(0.9986054) 684 PREX1 20q13.13 0 4 25 0 25 12 838 0.4481 0 0.0542713567839196 Chemokine signaling pathway(K)(0.998645)-Glypican pathway(N)(0.9973778)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9987508)-Signaling by Rho GTPases(R)(0.9980988)-TRAIL signaling pathway(N)(0.9988226) 685 MED15 22q11.21 0 0 2 1 262 12 558 0.4481 0 0.266331658291457 Generic Transcription Pathway(R)(0.9970968)-Glypican pathway(N)(0.9969938)-IFN-gamma pathway(N)(0.9982248) 686 OR2T1 1q44 0 0 16 0 15 12 413 0.4481 0 0.0311557788944724 Olfactory transduction(K)(0.9988236) 687 WRN 8p12 0 2 4 34 324 12 67 0.4481 1 0.365829145728643 Regulation of Telomerase(N)(0.9984858) 688 PEX10 1p36.32 0 0 0 2 208 12 78 0.4481 0 0.21105527638191 Peroxisome(K)(0.9985124) 689 HIST4H4 12p12.3 0 1 1 4 101 12 139 0.4481 0 0.107537688442211 Systemic lupus erythematosus(K)(0.99869) 690 PPM1D 17q23.2 0 20 25 0 100 12 69 0.4481 0 0.14572864321608 p53 signaling pathway(K)(0.9987632) 691 EIF3H 8q24.11 0 6 67 0 10 12 201 0.4481 0 0.0834170854271357 Metabolism of proteins(R)(0.998808) 692 AP4S1 14q12 0 1 1 1 126 12 121 0.4481 0 0.12964824120603 Lysosome(K)(0.9983566) 693 AP3S1 5q23.1 0 0 0 1 131 12 121 0.4481 0 0.132663316582915 Lysosome(K)(0.9976244) 694 SUMF1 3p26.2 0 2 2 10 89 12 121 0.4481 0 0.103517587939698 Lysosome(K)(0.9991282) 695 ARHGAP22 10q11.22 0 0 3 1 103 12 125 0.4481 0 0.107537688442211 Signaling by Rho GTPases(R)(0.9994732) 696 ARID1A 1p36.11 0 0 0 2 241 11 332 0.4535 1 0.244221105527638 Wnt signaling pathway(P)(0.9992508)-control of gene expression by vitamin d receptor(B)(0.9955844)-the information processing pathway at the ifn beta enhancer(B)(0.9977002) 697 GBF1 10q24.32 0 0 4 1 159 11 771 0.4535 0 0.164824120603015 Glypican pathway(N)(0.997702)-Membrane Trafficking(R)(0.9980562)-Plasma membrane estrogen receptor signaling(N)(0.9976134)-Proteogylcan syndecan-mediated signaling events(N)(0.9961002)-TRAIL signaling pathway(N)(0.9988022)-adp-ribosylation factor(B)(0.997217)-thrombin signaling and protease-activated receptors(B)(0.995843) 698 ALPI 2q37.1 0 0 0 0 112 11 1121 0.4535 0 0.112562814070352 Metabolic pathways(K)(0.998926) 699 POMGNT1 1p34.1 0 0 1 0 150 11 3 0.4535 0 0.151758793969849 O-Mannosyl glycan biosynthesis(K)(0.9964806) 700 NUP88 17p13.2 0 0 0 5 428 11 429 0.4535 0 0.435175879396985 HIV Life Cycle(R)(0.9963034)-Host Interactions of HIV factors(R)(0.9976664)-Influenza Life Cycle(R)(0.9985706)-Metabolism of carbohydrates(R)(0.9972184)-Metabolism of non-coding RNA(R)(0.9968482)-Transport of Mature Transcript to Cytoplasm(R)(0.996766) 701 THRA 17q21.1 0 40 35 2 151 11 329 0.4535 0 0.229145728643216 Neuroactive ligand-receptor interaction(K)(0.9992466)-Retinoic acid receptors-mediated signaling(N)(0.9988136)-map kinase inactivation of smrt corepressor(B)(0.9977518) 702 YWHAH 22q12.3 0 0 4 2 279 11 1262 0.4535 0 0.28643216080402 Alpha6Beta4Integrin(C)(0.9943562)-BMP receptor signaling(N)(0.9970502)-Cell cycle(K)(0.9979598)-EGF receptor signaling pathway(P)(0.9947232)-Endothelins(N)(0.9934808)-FGF signaling pathway(P)(0.9936304)-FoxO family signaling(N)(0.9955762)-Glypican pathway(N)(0.9984406)-IFN-gamma pathway(N)(0.9970126)-IL1-mediated signaling events(N)(0.9882542)-Neurotrophin signaling pathway(K)(0.996157)-Oocyte meiosis(K)(0.997864)-Parkinson disease(P)(0.9957088)-Plasma membrane estrogen receptor signaling(N)(0.9936812)-Proteogylcan syndecan-mediated signaling events(N)(0.9987918)-TNF alpha/NF-kB(C)(0.9984436)-TNF receptor signaling pathway(N)(0.9955524)-TRAIL signaling pathway(N)(0.9818948)-a6b1 and a6b4 Integrin signaling(N)(0.9939602)-akt signaling pathway(B)(0.9168526)-cell cycle: g2/m checkpoint(B)(0.980558)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9792738)-nfat and hypertrophy of the heart (B)(0.9981554)-p75(NTR)-mediated signaling(N)(0.9974378)-regulation of bad phosphorylation(B)(0.9849556)-regulation of pgc-1a(B)(0.9819934)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.9863288) 703 DPYSL2 8p21.2 0 0 0 30 360 11 132 0.4535 0 0.391959798994975 Axon guidance(K)(0.9990682) 704 GALT 9p13.3 0 0 4 0 173 11 1131 0.4535 0 0.177889447236181 Amino sugar and nucleotide sugar metabolism(K)(0.998933)-Metabolic pathways(K)(0.9985454) 705 GABRA3 23q28 0 0 2 6 161 11 283 0.4535 0 0.169849246231156 Neuroactive ligand-receptor interaction(K)(0.9989968)-cardiac protection against ros(B)(0.9942962)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9951526) 706 MAGOHB 12p13.2 0 1 6 4 90 11 128 0.4535 0 0.101507537688442 Spliceosome(K)(0.9982682) 707 MYO9A 15q23 0 2 1 2 146 11 169 0.4535 0 0.151758793969849 Nicotinic acetylcholine receptor signaling pathway(P)(0.9991218)-Signaling by Rho GTPases(R)(0.997518) 708 FGF20 8p22 0 1 5 31 354 11 684 0.4535 0 0.392964824120603 FGF signaling pathway(P)(0.9963238)-MAPK signaling pathway(K)(0.9988396)-Pathways in cancer(K)(0.9986286)-Regulation of actin cytoskeleton(K)(0.9989434)-Signaling by FGFR(R)(0.9801358) 709 ADCY8 8q24.22 0 5 55 1 15 11 1232 0.4535 0 0.0763819095477387 Calcium signaling pathway(K)(0.997981)-Chemokine signaling pathway(K)(0.9992374)-Dilated cardiomyopathy(K)(0.9847648)-Endothelin signaling pathway(P)(0.9343302)-Endothelins(N)(0.996778)-Gap junction(K)(0.9932574)-Gastric acid secretion(K)(0.9932184)-GnRH signaling pathway(K)(0.984597)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9971052)-LPA receptor mediated events(N)(0.9904472)-Long-term potentiation(K)(0.9786266)-Melanogenesis(K)(0.9957062)-Oocyte meiosis(K)(0.9983722)-Opioid Signalling(R)(0.9820412)-Pancreatic secretion(K)(0.9971912)-Progesterone-mediated oocyte maturation(K)(0.9898518)-Purine metabolism(K)(0.9990944)-Salivary secretion(K)(0.9914276)-Signalling by NGF(R)(0.9992208)-Taste transduction(K)(0.9944224)-Vascular smooth muscle contraction(K)(0.997958) 710 FLNA 23q28 0 0 7 5 144 11 771 0.4535 0 0.15678391959799 AndrogenReceptor(C)(0.9970274)-Focal adhesion(K)(0.998529)-Further platelet releasate(R)(0.9909046)-Integrin signalling pathway(P)(0.9980532)-MAPK signaling pathway(K)(0.9982932)-PNAT(P)(0.9940094)-TCR signaling in naive CD4+ T cells(N)(0.9977338)-TNF alpha/NF-kB(C)(0.9989278) 711 TH 11p15.5 0 0 0 0 171 11 1946 0.4535 0 0.171859296482412 Alpha-synuclein signaling(N)(0.9885368)-BMP receptor signaling(N)(0.9957232)-Glypican pathway(N)(0.9986298)-IFN-gamma pathway(N)(0.9982096)-IL1-mediated signaling events(N)(0.994391)-Metabolic pathways(K)(0.9995164)-Parkinson disease(P)(0.9980808)-Parkinson's disease(K)(0.9952706)-Plasma membrane estrogen receptor signaling(N)(0.9981112)-Synaptic Transmission(R)(0.9982844)-TNF receptor signaling pathway(N)(0.9983576)-Tyrosine metabolism(K)(0.9975148) 712 PCDH9 13q21.32 0 0 1 12 289 11 299 0.4535 0 0.303517587939699 Wnt signaling pathway(P)(0.9982856) 713 TOP3B 22q11.22 0 0 3 2 271 11 28 0.4535 0 0.277386934673367 Homologous recombination(K)(0.9983502) 714 DERL1 8q24.13 0 1 60 1 11 11 216 0.4535 0 0.0733668341708543 Amyotrophic lateral sclerosis (ALS)(K)(0.996715)-Protein processing in endoplasmic reticulum(K)(0.9989964) 715 KCNJ1 11q24.3 0 0 0 12 346 11 104 0.4535 0 0.359798994974874 Aldosterone-regulated sodium reabsorption(K)(0.9981782)-Gastric acid secretion(K)(0.9990946) 716 NRIP1 21q21.1 0 2 2 9 80 11 272 0.4535 0 0.0934673366834171 Androgen-mediated signaling(N)(0.995218)-AndrogenReceptor(C)(0.997485)-FOXA transcription factor networks(N)(0.9887804)-Retinoic acid receptors-mediated signaling(N)(0.9979026)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9956494) 717 COL6A2 21q22.3 0 0 5 0 68 11 330 0.4535 0 0.0733668341708543 ECM-receptor interaction(K)(0.9981068)-Focal adhesion(K)(0.9985522)-Integrin signalling pathway(P)(0.9981496)-Signaling by PDGF(R)(0.9991538) 718 TIRAP 11q24.2 0 0 0 15 341 11 195 0.4535 0 0.357788944723618 Toll-like receptor signaling pathway(K)(0.9991072)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9986368)-toll-like receptor pathway(B)(0.970622) 719 TNFRSF13C 22q13.2 0 0 1 2 278 11 319 0.4535 0 0.282412060301508 Cytokine-cytokine receptor interaction(K)(0.999104)-Intestinal immune network for IgA production(K)(0.9964562)-Primary immunodeficiency(K)(0.99867) 720 SUPT4H1 17q22 0 7 31 0 80 11 240 0.4535 0 0.118592964824121 Formation and Maturation of mRNA Transcript(R)(0.9988174)-HIV Life Cycle(R)(0.9976108)-Transcription(R)(0.998167) 721 OR8H3 11q11 0 1 1 3 148 11 389 0.4535 0 0.153768844221106 Olfactory transduction(K)(0.9984694) 722 SF3B3 16q22.1 0 0 2 7 471 11 232 0.4535 0 0.482412060301508 Formation and Maturation of mRNA Transcript(R)(0.9991076)-Spliceosome(K)(0.998592) 723 ADRB1 10q25.3 0 0 1 0 127 11 885 0.4535 0 0.128643216080402 Calcium signaling pathway(K)(0.998143)-Class A/1 (Rhodopsin-like receptors)(R)(0.993541)-Dilated cardiomyopathy(K)(0.9939534)-Endocytosis(K)(0.9990848)-Gap junction(K)(0.9967298)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9965972)-Neuroactive ligand-receptor interaction(K)(0.998375)-Receptor-ligand complexes bind G proteins(R)(0.9944126)-Salivary secretion(K)(0.9943588) 724 M6PR 12p13.31 0 2 5 2 85 11 263 0.4535 0 0.0944723618090452 Lysosome(K)(0.9984944)-Phagosome(K)(0.9976056) 725 ARHGAP30 1q23.3 0 1 26 0 5 11 125 0.4535 0 0.0321608040201005 Signaling by Rho GTPases(R)(0.9985216) 726 NLGN4X 23p22.31 0 1 0 5 160 11 135 0.4535 0 0.166834170854271 Cell adhesion molecules (CAMs)(K)(0.9985394) 727 SYK 9q22.2 0 1 0 1 149 10 1127 0.4602 1 0.151758793969849 Alpha-synuclein signaling(N)(0.991636)-B cell receptor signaling pathway(K)(0.9835314)-Fc epsilon RI signaling pathway(K)(0.98455)-Fc gamma R-mediated phagocytosis(K)(0.9983342)-Fc-epsilon receptor I signaling in mast cells(N)(0.9856622)-Formation of Platelet plug(R)(0.9984164)-Glypican pathway(N)(0.9960704)-IL1-mediated signaling events(N)(0.9955086)-IL12-mediated signaling events(N)(0.9968046)-IL2-mediated signaling events(N)(0.9966876)-IL23-mediated signaling events(N)(0.9872906)-Integrins in angiogenesis(N)(0.9972236)-LPA receptor mediated events(N)(0.997757)-Natural killer cell mediated cytotoxicity(K)(0.996842)-Signaling by Aurora kinases(N)(0.9863524)-Signaling events regulated by Ret tyrosine kinase(N)(0.9936184)-TCR signaling in naive CD4+ T cells(N)(0.9912278)-TNF receptor signaling pathway(N)(0.9970246)-TRAIL signaling pathway(N)(0.970675)-Thromboxane A2 receptor signaling(N)(0.9910364)-p75(NTR)-mediated signaling(N)(0.9992582) 728 GCAT 22q13.1 0 1 4 2 284 10 32 0.4602 0 0.292462311557789 Glycine, serine and threonine metabolism(K)(0.9978126) 729 CSH1 17q23.3 0 2 33 3 69 10 419 0.4602 0 0.107537688442211 Jak-STAT signaling pathway(K)(0.9984236)-Neuroactive ligand-receptor interaction(K)(0.9994974) 730 RAC1 7p22.1 0 0 2 1 67 10 2509 0.4602 0 0.0703517587939698 Adherens junction(K)(0.9909408)-Amyotrophic lateral sclerosis (ALS)(K)(0.994073)-Androgen-mediated signaling(N)(0.946077)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9932826)-Axon guidance(K)(0.9966526)-B cell receptor signaling pathway(K)(0.9793998)-BMP receptor signaling(N)(0.9915478)-Bacterial invasion of epithelial cells(K)(0.917301)-Chemokine signaling pathway(K)(0.9953532)-EGF receptor signaling pathway(P)(0.9800204)-EphrinB-EPHB pathway(N)(0.9364616)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9731252)-Fc epsilon RI signaling pathway(K)(0.9085334)-Fc gamma R-mediated phagocytosis(K)(0.992031)-Focal adhesion(K)(0.9651532)-Formation of Platelet plug(R)(0.9979344)-Glypican pathway(N)(0.9908518)-Host Interactions of HIV factors(R)(0.999322)-Huntington disease(P)(0.9973462)-IFN-gamma pathway(N)(0.9133366)-IL1-mediated signaling events(N)(0.977649)-IL2-mediated signaling events(N)(0.9894884)-IL6-mediated signaling events(N)(0.9926436)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9905698)-Integrin signalling pathway(P)(0.9966432)-Integrins in angiogenesis(N)(0.992326)-LPA receptor mediated events(N)(0.9899976)-Leukocyte transendothelial migration(K)(0.9956064)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9943912)-MAPK signaling pathway(K)(0.9981216)-Natural killer cell mediated cytotoxicity(K)(0.9929254)-Nectin adhesion pathway(N)(0.9807216)-Neurotrophin signaling pathway(K)(0.9955802)-Pancreatic secretion(K)(0.998978)-Pathways in cancer(K)(0.9990568)-Phagosome(K)(0.9978794)-Plasma membrane estrogen receptor signaling(N)(0.9519168)-Proteogylcan syndecan-mediated signaling events(N)(0.9954902)-Regulation of actin cytoskeleton(K)(0.9962496)-Shigellosis(K)(0.9757556)-Signaling by Rho GTPases(R)(0.9987956)-Signaling events mediated by PRL(N)(0.9899572)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9779822)-Signaling events regulated by Ret tyrosine kinase(N)(0.9905124)-Signalling by NGF(R)(0.9984054)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8033476)-TNF receptor signaling pathway(N)(0.9809826)-TRAIL signaling pathway(N)(0.9156434)-Thromboxane A2 receptor signaling(N)(0.983772)-Toll-like receptor signaling pathway(K)(0.9968482)-Viral myocarditis(K)(0.9938614)-Wnt signaling pathway(K)(0.9987256)-agrin in postsynaptic differentiation(B)(0.990154)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9746936)-map kinase inactivation of smrt corepressor(B)(0.9519498)-mcalpain and friends in cell motility(B)(0.946273)-p38 mapk signaling pathway(B)(0.9789646)-p75(NTR)-mediated signaling(N)(0.9958588)-phosphoinositides and their downstream targets(B)(0.9811944)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.937195)-rho cell motility signaling pathway(B)(0.8194494)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9850136)-y branching of actin filaments(B)(0.9142394) 731 COL4A3 2q36.3 0 0 1 0 110 10 308 0.4602 0 0.111557788944724 Integrin cell surface interactions(R)(0.9985186)-Integrin signalling pathway(P)(0.9982762)-Integrins in angiogenesis(N)(0.9984124)-Signaling by PDGF(R)(0.99669)-intrinsic prothrombin activation pathway(B)(0.9976956)-regulators of bone mineralization(B)(0.9811432) 732 CAMK4 5q22.1 0 0 0 2 139 10 1118 0.4602 0 0.141708542713568 BMP receptor signaling(N)(0.9959892)-Calcium signaling pathway(K)(0.9989882)-Endothelins(N)(0.992884)-Glypican pathway(N)(0.9992056)-IFN-gamma pathway(N)(0.9952378)-IL1-mediated signaling events(N)(0.992296)-Long-term potentiation(K)(0.9877422)-Neurotrophin signaling pathway(K)(0.9990404)-Opioid Signalling(R)(0.9978012)-Plasma membrane estrogen receptor signaling(N)(0.9979044)-Signaling events mediated by HDAC Class I(N)(0.99787)-Signalling by NGF(R)(0.9977904)-TNF receptor signaling pathway(N)(0.9925188)-TRAIL signaling pathway(N)(0.9939884)-nfat and hypertrophy of the heart (B)(0.995823)-p75(NTR)-mediated signaling(N)(0.994767)-regulation of pgc-1a(B)(0.9897476)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9885318) 733 HTR3B 11q23.2 0 0 1 17 369 10 9 0.4602 0 0.38894472361809 5HT3 type receptor mediated signaling pathway(P)(0.9985024) 734 ST3GAL1 8q24.22 0 4 52 0 20 10 1128 0.4602 0 0.0763819095477387 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.998296)-Metabolic pathways(K)(0.9988472) 735 IAPP 12p12.1 0 1 3 1 94 10 34 0.4602 0 0.0994974874371859 Maturity onset diabetes of the young(K)(0.9972052)-Regulation of beta-cell development(R)(0.9985912) 736 BID 22q11.21 0 0 2 3 283 10 1110 0.4602 0 0.289447236180905 Alzheimer's disease(K)(0.9992926)-Amyotrophic lateral sclerosis (ALS)(K)(0.995898)-Apoptosis(K)(0.9953184)-Apoptosis(R)(0.9974194)-FAS signaling pathway (CD95)(N)(0.9916468)-Natural killer cell mediated cytotoxicity(K)(0.9979892)-Pathways in cancer(K)(0.9979808)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9962584)-TNF receptor signaling pathway(N)(0.9935488)-TRAIL signaling pathway(N)(0.9921558)-Viral myocarditis(K)(0.9971112)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9846624)-p53 signaling pathway(K)(0.9965774) 737 ADRA1B 5q33.3 0 0 1 0 95 10 757 0.4602 0 0.0964824120603015 Calcium signaling pathway(K)(0.9994834)-Class A/1 (Rhodopsin-like receptors)(R)(0.9986114)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.998801)-LPA receptor mediated events(N)(0.9991512)-Neuroactive ligand-receptor interaction(K)(0.9991272)-Receptor-ligand complexes bind G proteins(R)(0.9981058)-Salivary secretion(K)(0.9979714)-Vascular smooth muscle contraction(K)(0.9983702)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9915774)-chrebp regulation by carbohydrates and camp(B)(0.9960806)-ion channels and their functional role in vascular endothelium(B)(0.9924984)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9847864)-ß-arrestins in gpcr desensitization(B)(0.9634686) 738 FHL5 6q16.1 0 0 1 1 255 10 10 0.4602 0 0.258291457286432 regulation of spermatogenesis by crem(B)(0.9982488) 739 ACTN1 14q24.1 0 0 2 2 176 10 1034 0.4602 0 0.180904522613065 Adherens junction(K)(0.9936822)-Amoebiasis(K)(0.9974)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.996145)-Focal adhesion(K)(0.9960408)-Formation of Platelet plug(R)(0.9988798)-Integrin signalling pathway(P)(0.9981042)-Leukocyte transendothelial migration(K)(0.9952156)-Nectin adhesion pathway(N)(0.99401)-Proteogylcan syndecan-mediated signaling events(N)(0.9938948)-Regulation of actin cytoskeleton(K)(0.9989682)-Systemic lupus erythematosus(K)(0.9989558)-Tight junction(K)(0.999701)-integrin signaling pathway(B)(0.9919982) 740 U2AF2 19q13.42 0 5 6 0 58 10 400 0.4602 0 0.0693467336683417 Formation and Maturation of mRNA Transcript(R)(0.9821842)-Influenza Life Cycle(R)(0.99777)-Spliceosome(K)(0.9979668)-Transcription(R)(0.9974842)-Transport of Mature Transcript to Cytoplasm(R)(0.996587) 741 PIGP 21q22.13 0 0 2 0 64 10 1304 0.4602 0 0.0663316582914573 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.9594352)-Metabolic pathways(K)(0.9980726)-Metabolism of proteins(R)(0.9991974) 742 ELOVL5 6p12.1 0 1 3 0 78 10 21 0.4602 0 0.0824120603015075 Biosynthesis of unsaturated fatty acids(K)(0.9979644) 743 ABCA12 2q35 0 0 1 0 84 10 44 0.4602 0 0.085427135678392 ABC transporters(K)(0.9994674) 744 IL1B 2q13 0 0 1 0 74 10 1272 0.4602 0 0.0753768844221105 Alzheimer's disease(K)(0.9987292)-Amoebiasis(K)(0.9978294)-Apoptosis(K)(0.996963)-Cellular roles of Anthrax toxin(N)(0.930215)-Chagas disease(K)(0.9928948)-Cytokine-cytokine receptor interaction(K)(0.998658)-Cytosolic DNA-sensing pathway(K)(0.9959264)-Graft-versus-host disease(K)(0.9862928)-Hematopoietic cell lineage(K)(0.9977354)-IFN-gamma pathway(N)(0.9987734)-IL1-mediated signaling events(N)(0.9862012)-IL12-mediated signaling events(N)(0.9983692)-IL23-mediated signaling events(N)(0.9703012)-Leishmaniasis(K)(0.980771)-MAPK signaling pathway(K)(0.9983992)-Malaria(K)(0.9959612)-NOD-like receptor signaling pathway(K)(0.9963026)-Prion diseases(K)(0.9967958)-Toll-like receptor signaling pathway(K)(0.9950382)-Type I diabetes mellitus(K)(0.9921056) 745 LRP6 12p13.2 0 2 6 5 104 10 866 0.4602 0 0.117587939698492 Alzheimer disease-presenilin pathway(P)(0.9978934)-Glypican pathway(N)(0.9978458)-Presenilin action in Notch and Wnt signaling(N)(0.9897538)-Wnt signaling pathway(K)(0.9992098)-Wnt signaling pathway(P)(0.9997108)-Wnt(C)(0.9973894)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.996114)-multi-step regulation of transcription by pitx2(B)(0.9959364)-segmentation clock(B)(0.9937236) 746 ITGB3 17q21.32 0 0 2 0 167 10 1344 0.4602 0 0.169849246231156 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9919668)-Cell surface interactions at the vascular wall(R)(0.996499)-Dilated cardiomyopathy(K)(0.9947126)-ECM-receptor interaction(K)(0.9849616)-Focal adhesion(K)(0.997617)-Formation of Platelet plug(R)(0.9987388)-Hematopoietic cell lineage(K)(0.9977558)-Hypertrophic cardiomyopathy (HCM)(K)(0.9929366)-IFN-gamma pathway(N)(0.9971618)-Integrin cell surface interactions(R)(0.9924582)-Integrin signalling pathway(P)(0.9976728)-Integrins in angiogenesis(N)(0.9930064)-Nectin adhesion pathway(N)(0.998596)-Phagosome(K)(0.9981354)-Plasma membrane estrogen receptor signaling(N)(0.9927132)-Proteogylcan syndecan-mediated signaling events(N)(0.9987642)-Regulation of actin cytoskeleton(K)(0.9976792)-Signaling events mediated by PTP1B(N)(0.9918274)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.991096)-phospholipids as signalling intermediaries(B)(0.9810438) 747 IL9 5q31.1 0 0 0 2 115 10 347 0.4602 0 0.117587939698492 Asthma(K)(0.998076)-Cytokine-cytokine receptor interaction(K)(0.9979194)-Jak-STAT signaling pathway(K)(0.998682) 748 FARS2 6p25.1 0 1 3 3 90 10 41 0.4602 0 0.0974874371859296 Aminoacyl-tRNA biosynthesis(K)(0.9994622) 749 HS2ST1 1p22.3 0 0 0 3 186 10 26 0.4602 0 0.189949748743719 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.99849) 750 THBS3 1q22 0 1 26 0 4 10 559 0.4602 0 0.0311557788944724 ECM-receptor interaction(K)(0.997834)-Focal adhesion(K)(0.9987012)-Formation of Platelet plug(R)(0.998002)-Malaria(K)(0.9965348)-Phagosome(K)(0.9992824)-Signaling by PDGF(R)(0.9965376)-TGF-beta signaling pathway(K)(0.996735) 751 HP 16q22.3 0 0 0 11 508 10 39 0.4602 0 0.521608040201005 amb2 Integrin signaling(N)(0.9990904) 752 MCC 5q22.2 0 0 0 2 144 10 136 0.4602 0 0.146733668341709 TNF alpha/NF-kB(C)(0.9992336) 753 HSD17B1 17q21.31 0 2 5 2 206 10 1132 0.4602 0 0.21608040201005 Metabolic pathways(K)(0.997461)-Steroid hormone biosynthesis(K)(0.9977668) 754 HPRT1 23q26.2 0 0 2 6 170 10 1192 0.4602 0 0.178894472361809 Drug metabolism - other enzymes(K)(0.9892822)-Metablism of nucleotides(R)(0.9968898)-Metabolic pathways(K)(0.9976586)-Purine metabolism(K)(0.9985326) 755 OR8G1 11q24.2 0 0 0 14 358 10 389 0.4602 0 0.373869346733668 Olfactory transduction(K)(0.9986474) 756 BRF2 8p12 0 39 37 9 170 10 136 0.4602 0 0.256281407035176 Transcription(R)(0.999448) 757 IQSEC3 12p13.33 0 1 6 1 74 10 204 0.4602 0 0.0824120603015075 Endocytosis(K)(0.9990864) 758 FGF2 4q27 0 1 2 1 110 9 1119 0.4602 0 0.114572864321608 Angiogenesis(P)(0.9957614)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9914044)-FGF signaling pathway(P)(0.9953414)-Glypican pathway(N)(0.9990352)-Integrins in angiogenesis(N)(0.9944946)-MAPK signaling pathway(K)(0.9964476)-Pathways in cancer(K)(0.9985428)-Proteogylcan syndecan-mediated signaling events(N)(0.9981872)-Regulation of actin cytoskeleton(K)(0.9966198) 759 PRKAR2B 7q22.3 0 0 1 1 89 9 705 0.4602 0 0.0914572864321608 Apoptosis(K)(0.9970512)-Endothelin signaling pathway(P)(0.9960144)-G2/M Transition(R)(0.9985794)-Hedgehog signaling pathway(P)(0.9959168)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9992236)-Insulin signaling pathway(K)(0.998748)-Opioid Signalling(R)(0.9985166)-Signalling by NGF(R)(0.9985044)-actions of nitric oxide in the heart(B)(0.9985784)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9722926)-akap95 role in mitosis and chromosome dynamics(B)(0.9941204)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9775576)-gata3 participate in activating the th2 cytokine genes expression(B)(0.990312)-how progesterone initiates the oocyte maturation(B)(0.9942754)-mcalpain and friends in cell motility(B)(0.9977196)-nitric oxide signaling pathway(B)(0.9902574)-phospholipase c-epsilon pathway(B)(0.9887336)-regulation of bad phosphorylation(B)(0.938043)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9658124)-repression of pain sensation by the transcriptional regulator dream(B)(0.9877364)-rho-selective guanine exchange factor akap13 mediates stress fiber formation(B)(0.9933966)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9923364)-transcription regulation by methyltransferase of carm1(B)(0.9916856) 760 MYH6 14q11.2 0 1 3 0 89 9 632 0.4602 0 0.0934673366834171 Cardiac muscle contraction(K)(0.9984094)-Dilated cardiomyopathy(K)(0.999149)-Hypertrophic cardiomyopathy (HCM)(K)(0.9974802)-Muscle contraction(R)(0.9971108)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9993648)-Tight junction(K)(0.9978782)-Viral myocarditis(K)(0.9975826)-Wnt signaling pathway(P)(0.9984672) 761 AVP 20p13 0 1 3 1 58 9 279 0.4602 0 0.0633165829145729 Class A/1 (Rhodopsin-like receptors)(R)(0.9989088)-Receptor-ligand complexes bind G proteins(R)(0.9980176)-Vasopressin synthesis(P)(0.9702616)-Vasopressin-regulated water reabsorption(K)(0.9990632)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9943084) 762 NT5M 17p11.2 0 2 2 6 378 9 1187 0.4602 0 0.389949748743719 Metabolic pathways(K)(0.998897)-Nicotinate and nicotinamide metabolism(K)(0.856212)-Purine metabolism(K)(0.9977714)-Pyrimidine metabolism(K)(0.9991496) 763 GJD2 15q14 0 0 1 4 170 9 146 0.4602 0 0.175879396984925 Gap junction trafficking and regulation(R)(0.9984756)-Gap junction(K)(0.9982926)-Synaptic Transmission(R)(0.9986012) 764 PRKAR1B 7p22.3 0 0 7 0 63 9 720 0.4602 0 0.0703517587939698 Apoptosis(K)(0.9985338)-Endothelin signaling pathway(P)(0.9968668)-Hedgehog signaling pathway(P)(0.9919354)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9975468)-Insulin signaling pathway(K)(0.998202)-Metabotropic glutamate receptor group I pathway(P)(0.9689498)-Opioid Signalling(R)(0.9986202)-Signalling by NGF(R)(0.9979064)-TGFBR(C)(0.9979826)-actions of nitric oxide in the heart(B)(0.997665)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9951854)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9675038)-gata3 participate in activating the th2 cytokine genes expression(B)(0.9923708)-how progesterone initiates the oocyte maturation(B)(0.9921504)-mcalpain and friends in cell motility(B)(0.9986204)-nitric oxide signaling pathway(B)(0.994542)-phospholipase c-epsilon pathway(B)(0.9876498)-regulation of bad phosphorylation(B)(0.8966254)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.989598)-repression of pain sensation by the transcriptional regulator dream(B)(0.9623356)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9963322)-transcription regulation by methyltransferase of carm1(B)(0.9857684) 765 SERPINE1 7q22.1 0 0 5 3 99 9 834 0.4602 0 0.107537688442211 Chagas disease(K)(0.999268)-Complement and coagulation cascades(K)(0.9959142)-Formation of Platelet plug(R)(0.998155)-Glypican pathway(N)(0.999174)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.996911)-IFN-gamma pathway(N)(0.9964636)-fibrinolysis pathway(B)(0.896727)-p53 signaling pathway(K)(0.997602) 766 ITGA4 2q31.3 0 0 0 0 71 9 898 0.4602 0 0.071356783919598 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9953194)-Cell adhesion molecules (CAMs)(K)(0.9989084)-Cell surface interactions at the vascular wall(R)(0.997452)-Dilated cardiomyopathy(K)(0.999487)-ECM-receptor interaction(K)(0.9923978)-Focal adhesion(K)(0.9975496)-Hematopoietic cell lineage(K)(0.996201)-Hypertrophic cardiomyopathy (HCM)(K)(0.9919784)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9928254)-Integrin cell surface interactions(R)(0.9959434)-Integrin signalling pathway(P)(0.99874)-Intestinal immune network for IgA production(K)(0.9947156)-Leishmaniasis(K)(0.9967442)-Leukocyte transendothelial migration(K)(0.992702)-Regulation of actin cytoskeleton(K)(0.999147)-VEGFR3 signaling in lymphatic endothelium(N)(0.9727178) 767 UBE2D1 10q21.1 0 0 1 0 105 9 553 0.4602 0 0.106532663316583 APC/C-mediated degradation of cell cycle proteins(R)(0.998088)-Cell Cycle Checkpoints(R)(0.9986118)-Protein processing in endoplasmic reticulum(K)(0.9992084)-Signaling by BMP(R)(0.9968502)-Signaling by TGF beta(R)(0.981786)-TGFBR(C)(0.9972642)-Ubiquitin mediated proteolysis(K)(0.9973214)-fibrinolysis pathway(B)(0.9963946)-hypoxia and p53 in the cardiovascular system(B)(0.9949946)-hypoxia-inducible factor in the cardivascular system(B)(0.9936508)-regulation of transcriptional activity by pml(B)(0.992982)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9954726) 768 GAPDH 12p13.31 0 1 5 1 75 9 1431 0.4602 0 0.0824120603015075 Alzheimer's disease(K)(0.9985572)-Glucose Regulation of Insulin Secretion(R)(0.9972664)-Huntington disease(P)(0.998438)-Metabolic pathways(K)(0.998821)-Metabolism of carbohydrates(R)(0.998151)-downregulated of mta-3 in er-negative breast tumors(B)(0.9945044) 769 FCGR1A 1q21.2 0 1 15 0 8 9 467 0.4602 0 0.0241206030150754 Fc gamma R-mediated phagocytosis(K)(0.9988192)-Hematopoietic cell lineage(K)(0.998976)-Leishmaniasis(K)(0.9964148)-Phagosome(K)(0.9986126)-Systemic lupus erythematosus(K)(0.998439) 770 ABCB7 23q13.3 0 0 0 7 156 9 44 0.4602 0 0.163819095477387 ABC transporters(K)(0.9982132) 771 NCOA1 2p23.3 0 0 1 3 89 9 804 0.4602 1 0.0934673366834171 Androgen-mediated signaling(N)(0.9660276)-Glypican pathway(N)(0.9961604)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9989194)-IFN-gamma pathway(N)(0.9960978)-Retinoic acid receptors-mediated signaling(N)(0.996413)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9966798)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9774126)-erythropoietin mediated neuroprotection through nf-kb(B)(0.9797676)-hypoxia and p53 in the cardiovascular system(B)(0.9922236)-hypoxia-inducible factor in the cardivascular system(B)(0.9490082)-il-7 signal transduction(B)(0.9878488)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.995906)-multi-step regulation of transcription by pitx2(B)(0.9940268)-nfat and hypertrophy of the heart (B)(0.9961228)-nfkb activation by nontypeable hemophilus influenzae(B)(0.9856358)-role of erbb2 in signal transduction and oncology(B)(0.989825)-tgf beta signaling pathway(B)(0.9888434)-the information processing pathway at the ifn beta enhancer(B)(0.9974386) 772 MAN1C1 1p36.11 0 0 0 1 223 9 1281 0.4602 0 0.225125628140704 Metabolic pathways(K)(0.99906)-N-Glycan biosynthesis(K)(0.998818)-Protein processing in endoplasmic reticulum(K)(0.9986208)-er associated degradation (erad) pathway(B)(0.9977672) 773 PDHB 3p14.3 0 0 0 0 167 9 1243 0.4602 0 0.167839195979899 Butanoate metabolism(K)(0.845096)-Glucose Regulation of Insulin Secretion(R)(0.9989444)-Metabolic pathways(K)(0.9980838)-Metabolism of carbohydrates(R)(0.9980276)-Pyruvate metabolism(K)(0.9971488)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9965214)-Valine, leucine and isoleucine biosynthesis(K)(0.9963976) 774 SIRT1 10q21.3 0 0 1 0 124 9 315 0.4602 0 0.125628140703518 Androgen-mediated signaling(N)(0.984986)-FoxO family signaling(N)(0.9985792)-Regulation of retinoblastoma protein(N)(0.9980544)-Signaling events mediated by HDAC Class I(N)(0.9973876)-p53 pathway(P)(0.9979434)-regulation of transcriptional activity by pml(B)(0.993101) 775 RARS 5q35.1 0 0 2 0 87 9 44 0.4602 0 0.0894472361809045 Aminoacyl-tRNA biosynthesis(K)(0.9987932)-tRNA Aminoacylation(R)(0.996175) 776 EPS15 1p32.3 0 0 2 1 149 9 345 0.4602 1 0.152763819095477 EGFR1(C)(0.9980474)-Endocytosis(K)(0.9992874)-Signaling by EGFR(R)(0.998597)-endocytotic role of ndk phosphins and dynamin(B)(0.9959814) 777 PRKAA2 1p32.2 0 2 0 1 134 9 329 0.4602 0 0.137688442211055 Activated AMPK stimulates fatty-acid oxidation in muscle(R)(0.9865862)-Adipocytokine signaling pathway(K)(0.9967038)-Hypertrophic cardiomyopathy (HCM)(K)(0.9974612)-Insulin signaling pathway(K)(0.9987258)-Regulation of autophagy(K)(0.9983836)-chrebp regulation by carbohydrates and camp(B)(0.9964484)-mTOR signaling pathway(K)(0.9958388) 778 POLE 12q24.33 0 0 2 0 113 9 1391 0.4602 0 0.115577889447236 Base excision repair(K)(0.9947574)-DNA Repair(R)(0.9985766)-DNA replication(K)(0.9946052)-G1/S Transition(R)(0.9959274)-Metabolic pathways(K)(0.9991486)-Nucleotide excision repair(K)(0.9952736)-Purine metabolism(K)(0.9976984)-Pyrimidine metabolism(K)(0.9912762)-S Phase(R)(0.9900532)-Telomere Maintenance(R)(0.9964392) 779 RPS6KA2 6q27 0 1 1 4 229 9 646 0.4602 0 0.236180904522613 EGFR1(C)(0.9986762)-Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade(P)(0.9825042)-Long-term potentiation(K)(0.9961296)-MAPK signaling pathway(K)(0.9984984)-Neurotrophin signaling pathway(K)(0.9967248)-Oocyte meiosis(K)(0.997429)-Progesterone-mediated oocyte maturation(K)(0.997448)-Ras Pathway(P)(0.9026536)-Signalling by NGF(R)(0.9975462)-mTOR signaling pathway(K)(0.9978482) 780 SRP9 1q42.12 0 1 20 0 10 9 56 0.4602 0 0.0311557788944724 Insulin Synthesis and Secretion(R)(0.999538)-Protein export(K)(0.9964222) 781 RANBP2 2q13 0 0 0 0 71 9 608 0.4602 0 0.071356783919598 HIV Life Cycle(R)(0.9937716)-Host Interactions of HIV factors(R)(0.9979198)-Influenza Life Cycle(R)(0.9982354)-M Phase(R)(0.9970794)-Metabolism of carbohydrates(R)(0.9979158)-Metabolism of non-coding RNA(R)(0.9941784)-Signaling events mediated by HDAC Class I(N)(0.9987574)-Transport of Mature Transcript to Cytoplasm(R)(0.9914566)-role of ran in mitotic spindle regulation(B)(0.9929866) 782 SMURF2 17q24.1 0 3 32 0 85 9 931 0.4602 0 0.120603015075377 BMP receptor signaling(N)(0.9880194)-Endocytosis(K)(0.9985008)-Glypican pathway(N)(0.9986516)-IFN-gamma pathway(N)(0.9981366)-Signaling by BMP(R)(0.98144)-TGF-beta signaling pathway(K)(0.994241)-TGF-beta signaling pathway(P)(0.9961236)-TGFBR(C)(0.9970238)-Ubiquitin mediated proteolysis(K)(0.994786) 783 C1QBP 17p13.2 0 0 0 4 425 9 32 0.4602 0 0.431155778894472 Formation of Fibrin Clot (Clotting Cascade)(R)(0.9989356) 784 ADRA2C 4p16.2 0 0 1 0 138 9 461 0.4602 0 0.139698492462312 Class A/1 (Rhodopsin-like receptors)(R)(0.998103)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.99826)-Neuroactive ligand-receptor interaction(K)(0.9997396)-Receptor-ligand complexes bind G proteins(R)(0.9960862) 785 CUL1 7q36.1 0 0 3 2 94 9 983 0.4602 0 0.0994974874371859 Cell cycle(K)(0.992443)-Circadian rhythm - mammal(K)(0.981413)-G1/S Transition(R)(0.9854302)-NOTCH(C)(0.9957518)-Oocyte meiosis(K)(0.9976642)-Parkinson disease(P)(0.991324)-Protein processing in endoplasmic reticulum(K)(0.9982248)-S Phase(R)(0.9138582)-TGF-beta signaling pathway(K)(0.9953438)-TGFBR(C)(0.9959132)-TNF alpha/NF-kB(C)(0.9993534)-Ubiquitin mediated proteolysis(K)(0.9979194)-Wnt signaling pathway(K)(0.997683)-Wnt(C)(0.9966334) 786 NR0B2 1p36.11 0 0 0 2 236 9 124 0.4602 0 0.239195979899497 AndrogenReceptor(C)(0.9981736)-NR transcription pathway(R)(0.9996364)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9973082) 787 MPHOSPH6 16q23.3 0 0 0 6 509 9 59 0.4602 0 0.517587939698492 RNA degradation(K)(0.9972234) 788 NCBP1 9q22.33 0 0 0 2 153 9 432 0.4602 0 0.155778894472362 Formation and Maturation of mRNA Transcript(R)(0.9782958)-HIV Life Cycle(R)(0.9964642)-Influenza Life Cycle(R)(0.9980872)-Metabolism of non-coding RNA(R)(0.9965644)-Spliceosome(K)(0.998061)-Transcription(R)(0.9985764)-Transport of Mature Transcript to Cytoplasm(R)(0.9858822)-mRNA Processing(R)(0.9943918) 789 FABP4 8q21.13 0 5 59 0 18 9 153 0.4602 0 0.0824120603015075 Metabolism of lipids and lipoproteins(R)(0.9985916)-PPAR signaling pathway(K)(0.9984274) 790 CYBA 16q24.3 0 0 2 11 474 9 297 0.4602 0 0.489447236180905 Leishmaniasis(K)(0.9994954)-Leukocyte transendothelial migration(K)(0.9986876)-Phagosome(K)(0.999075) 791 TUBB4Q 4q35.2 0 0 0 5 138 9 557 0.4602 0 0.143718592964824 Gap junction(K)(0.9971962)-Huntington disease(P)(0.998533)-Metabolism of proteins(R)(0.9986506)-Pathogenic Escherichia coli infection(K)(0.9967706)-Phagosome(K)(0.997391) 792 SETDB2 13q14.3 0 0 0 12 294 9 44 0.4602 0 0.307537688442211 Lysine degradation(K)(0.9976026) 793 CSNK2A2 16q21 0 0 0 9 497 9 647 0.4602 0 0.508542713567839 Adherens junction(K)(0.992507)-TNF alpha/NF-kB(C)(0.997671)-Tight junction(K)(0.9976966)-Wnt signaling pathway(K)(0.9978726)-Wnt signaling pathway(P)(0.9986788)-Wnt(C)(0.9924956) 794 MGST2 4q31.1 0 1 0 1 105 9 113 0.4602 0 0.107537688442211 Drug metabolism - cytochrome P450(K)(0.9983244)-Glutathione metabolism(K)(0.9983486)-Metabolism of xenobiotics by cytochrome P450(K)(0.99728) 795 PEX12 17q12 0 1 4 4 197 9 78 0.4602 0 0.207035175879397 Peroxisome(K)(0.9993688) 796 CLNS1A 11q14.1 0 33 36 4 121 9 49 0.4602 0 0.194974874371859 Metabolism of non-coding RNA(R)(0.9991132) 797 SERPIND1 22q11.21 0 0 2 1 271 9 69 0.4602 0 0.275376884422111 Complement and coagulation cascades(K)(0.999286) 798 RHOT2 16p13.3 0 0 10 1 49 9 125 0.4602 0 0.0603015075376884 Signaling by Rho GTPases(R)(0.9985562) 799 RPS14 5q33.1 0 0 1 0 100 9 306 0.4602 0 0.101507537688442 Influenza Life Cycle(R)(0.9978676)-Metabolism of proteins(R)(0.9971346) 800 CYP2D6 22q13.2 0 0 1 1 280 9 110 0.4602 0 0.283417085427136 Biological oxidations(R)(0.9985398)-Drug metabolism - cytochrome P450(K)(0.9971846) 801 LEFTY2 1q42.12 0 2 19 0 12 9 241 0.4602 0 0.0331658291457286 Formation of Platelet plug(R)(0.998767)-TGF-beta signaling pathway(K)(0.997892)-TGF-beta signaling pathway(P)(0.9981204) 802 CACNA1H 16p13.3 0 1 9 1 50 9 418 0.4602 0 0.0613065326633166 Calcium signaling pathway(K)(0.9997086)-MAPK signaling pathway(K)(0.9985846) 803 TNFRSF19 13q12.12 0 0 2 3 236 9 266 0.4602 0 0.242211055276382 Cytokine-cytokine receptor interaction(K)(0.9987712) 804 GRIK3 1p34.3 0 0 2 0 159 9 395 0.4602 0 0.161809045226131 Huntington disease(P)(0.9983894)-Neuroactive ligand-receptor interaction(K)(0.9975534) 805 ATXN3 14q32.12 0 0 0 3 189 9 167 0.4602 0 0.192964824120603 Protein processing in endoplasmic reticulum(K)(0.9988832) 806 NPFFR2 4q13.3 0 0 5 0 81 9 351 0.4602 0 0.0864321608040201 Class A/1 (Rhodopsin-like receptors)(R)(0.9990164)-Neuroactive ligand-receptor interaction(K)(0.9957082) 807 TGFBR1 9q22.33 0 0 0 1 155 8 1580 0.4602 0 0.15678391959799 Adherens junction(K)(0.9960876)-Chagas disease(K)(0.998582)-Chronic myeloid leukemia(K)(0.988864)-Cytokine-cytokine receptor interaction(K)(0.9991948)-Endocytosis(K)(0.9983946)-Glypican pathway(N)(0.9982854)-IFN-gamma pathway(N)(0.9978058)-MAPK signaling pathway(K)(0.998726)-Pathways in cancer(K)(0.9985548)-TGF-beta signaling pathway(K)(0.9933622)-TGF-beta signaling pathway(P)(0.9921704)-TGFBR(C)(0.9963016)-Wnt signaling pathway(P)(0.998893) 808 ANGPT2 8p23.1 0 1 0 32 359 8 188 0.4602 0 0.393969849246231 Angiogenesis(P)(0.9994382)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9951272)-Cell surface interactions at the vascular wall(R)(0.998936) 809 IFNG 12q15 0 3 12 0 39 8 1546 0.4602 0 0.0542713567839196 Amoebiasis(K)(0.9986742)-Antigen processing and presentation(K)(0.9954562)-BMP receptor signaling(N)(0.9821372)-Chagas disease(K)(0.9934322)-Cytokine-cytokine receptor interaction(K)(0.9994526)-Endothelins(N)(0.9938772)-Glypican pathway(N)(0.9963048)-IFN-gamma pathway(N)(0.9948454)-IL1-mediated signaling events(N)(0.9911064)-IL12-mediated signaling events(N)(0.9755098)-IL2-mediated signaling events(N)(0.9863834)-IL23-mediated signaling events(N)(0.9831126)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9973008)-Jak-STAT signaling pathway(K)(0.9969694)-Leishmaniasis(K)(0.9760856)-Malaria(K)(0.9975788)-Natural killer cell mediated cytotoxicity(K)(0.9948338)-Plasma membrane estrogen receptor signaling(N)(0.9950996)-Proteasome(K)(0.9909364)-Regulation of Telomerase(N)(0.9965326)-Regulation of autophagy(K)(0.994429)-Systemic lupus erythematosus(K)(0.9984846)-T cell receptor signaling pathway(K)(0.9925516)-TCR signaling in naive CD4+ T cells(N)(0.99303)-TGF-beta signaling pathway(K)(0.9971064)-TNF receptor signaling pathway(N)(0.9974006)-Type I diabetes mellitus(K)(0.988214)-no2-dependent il-12 pathway in nk cells(B)(0.855752) 810 ACTN4 19q13.2 0 0 4 1 76 8 860 0.4602 0 0.0814070351758794 Adherens junction(K)(0.9962704)-Amoebiasis(K)(0.9959612)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.99324)-Focal adhesion(K)(0.997343)-Formation of Platelet plug(R)(0.9971844)-Integrin signalling pathway(P)(0.99817)-Leukocyte transendothelial migration(K)(0.9985226)-Regulation of actin cytoskeleton(K)(0.999137)-Systemic lupus erythematosus(K)(0.9986398)-Tight junction(K)(0.998153)-integrin signaling pathway(B)(0.994429) 811 GNB4 3q26.33 0 0 9 0 16 8 739 0.4602 0 0.0251256281407035 Beta1 adrenergic receptor signaling pathway(P)(0.8033666)-Chemokine signaling pathway(K)(0.9956042)-Formation of Platelet plug(R)(0.997532)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9962468)-Opioid Signalling(R)(0.9978844)-Receptor-ligand complexes bind G proteins(R)(0.9987282)-Wnt signaling pathway(P)(0.9982344) 812 SRP19 5q22.2 0 0 0 2 138 8 56 0.4602 0 0.14070351758794 Insulin Synthesis and Secretion(R)(0.9980196)-Protein export(K)(0.9990896) 813 PAX5 9p13.2 0 0 1 0 164 8 25 0.4602 1 0.165829145728643 ID(C)(0.999554) 814 ABCC9 12p12.1 0 0 5 2 84 8 44 0.4602 0 0.0914572864321608 ABC transporters(K)(0.9982234) 815 B4GALT2 1p34.1 0 0 2 0 119 8 1131 0.4602 0 0.121608040201005 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.996429)-Metabolic pathways(K)(0.9973134)-N-Glycan biosynthesis(K)(0.9956698) 816 TNFSF11 13q14.11 0 0 0 8 278 8 318 0.4602 0 0.287437185929648 Cytokine-cytokine receptor interaction(K)(0.9994302)-IL6-mediated signaling events(N)(0.9989544)-bone remodeling(B)(0.9986838) 817 LDHA 11p15.1 0 1 3 1 120 8 1257 0.4602 0 0.125628140703518 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9971902)-Metabolic pathways(K)(0.9983074)-Metabolism of carbohydrates(R)(0.9984426)-Pyruvate metabolism(K)(0.995252)-hypoxia-inducible factor in the cardivascular system(B)(0.8599108) 818 SC4MOL 4q32.3 0 0 0 1 110 8 1123 0.4602 0 0.111557788944724 Metabolic pathways(K)(0.9980538)-Steroid biosynthesis(K)(0.9967138) 819 GSPT2 23p11.22 0 0 1 4 140 8 201 0.4602 0 0.14572864321608 Metabolism of proteins(R)(0.9980066) 820 ARHGAP10 4q31.23 0 0 2 2 110 8 469 0.4602 0 0.114572864321608 Apoptosis(R)(0.99909)-Bacterial invasion of epithelial cells(K)(0.9973734)-Integrin signalling pathway(P)(0.9993636)-Signaling by Rho GTPases(R)(0.998328) 821 STX6 1q25.3 0 0 18 0 11 8 40 0.4602 0 0.0291457286432161 Botulinum neurotoxicity(R)(0.9921914)-SNARE interactions in vesicular transport(K)(0.9989674) 822 FRAP1 1p36.22 0 1 1 1 239 8 883 0.4602 0 0.24321608040201 Alpha6Beta4Integrin(C)(0.9959572)-Endothelins(N)(0.9967328)-Glypican pathway(N)(0.9972788)-Hypoxia response via HIF activation(P)(0.9947544)-IFN-gamma pathway(N)(0.996135)-IL12-mediated signaling events(N)(0.9983824)-IL2-mediated signaling events(N)(0.9987922)-Interleukin signaling pathway(P)(0.99303)-Regulation of Telomerase(N)(0.997731)-Signalling by NGF(R)(0.9989334)-TRAIL signaling pathway(N)(0.9968546)-b cell survival pathway(B)(0.9913866)-ctcf: first multivalent nuclear factor(B)(0.9912078)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9917124) 823 HNF1A 12q24.31 0 0 0 0 123 8 578 0.4602 0 0.123618090452261 FOXA transcription factor networks(N)(0.9827738)-Glypican pathway(N)(0.9962898)-Maturity onset diabetes of the young(K)(0.9949934)-Presenilin action in Notch and Wnt signaling(N)(0.9975586)-Regulation of beta-cell development(R)(0.9944316)-growth hormone signaling pathway(B)(0.9962188)-role of mal in rho-mediated activation of srf(B)(0.997274)-wnt signaling pathway(B)(0.9949072) 824 DDOST 1p36.12 0 0 0 2 251 8 1310 0.4602 0 0.25427135678392 Insulin Synthesis and Secretion(R)(0.9957346)-Metabolic pathways(K)(0.9977398)-N-Glycan biosynthesis(K)(0.9983442)-Protein processing in endoplasmic reticulum(K)(0.9978356) 825 GPX1 3p21.31 0 0 0 0 202 8 332 0.4602 0 0.203015075376884 Amyotrophic lateral sclerosis (ALS)(K)(0.997768)-Arachidonic acid metabolism(K)(0.9987028)-Glutathione metabolism(K)(0.9980246)-Huntington's disease(K)(0.9985712)-cardiac protection against ros(B)(0.9963328) 826 NONO 23q13.1 0 0 0 8 164 8 14 0.4602 1 0.17286432160804 Circadian rhythm pathway(N)(0.9992) 827 PTGER1 19p13.12 0 0 6 1 97 8 504 0.4602 0 0.104522613065327 Calcium signaling pathway(K)(0.9984176)-Neuroactive ligand-receptor interaction(K)(0.998023)-PI3 kinase pathway(P)(0.9981792)-chrebp regulation by carbohydrates and camp(B)(0.9967618)-eicosanoid metabolism(B)(0.9970794)-ion channels and their functional role in vascular endothelium(B)(0.9977362)-phospholipase c-epsilon pathway(B)(0.9928092)-roles of ß arrestin dependent recruitment of src kinases in gpcr signaling(B)(0.9904186)-ß-arrestins in gpcr desensitization(B)(0.9969922) 828 CYB5A 18q22.3 0 0 3 1 191 8 13 0.4602 0 0.195979899497487 Metabolism of vitamins and cofactors(R)(0.9988046) 829 GYPA 4q31.22 0 0 0 2 100 8 133 0.4602 0 0.10251256281407 Hematopoietic cell lineage(K)(0.9989074)-Malaria(K)(0.998617) 830 NARS 18q21.31 0 0 1 2 205 8 44 0.4602 0 0.209045226130653 Aminoacyl-tRNA biosynthesis(K)(0.9987562)-tRNA Aminoacylation(R)(0.9955948) 831 CHST4 16q22.3 0 0 0 11 504 8 15 0.4602 0 0.517587939698492 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.9984686) 832 SCD 10q24.31 0 0 2 1 142 8 84 0.4602 0 0.14572864321608 Biosynthesis of unsaturated fatty acids(K)(0.997344)-PPAR signaling pathway(K)(0.997166) 833 TBC1D4 13q22.2 0 0 0 6 276 8 715 0.4602 0 0.283417085427136 Glypican pathway(N)(0.9985568)-Plasma membrane estrogen receptor signaling(N)(0.997506)-Proteogylcan syndecan-mediated signaling events(N)(0.997645)-TRAIL signaling pathway(N)(0.9973536) 834 MYO1C 17p13.3 0 0 2 8 404 8 46 0.4602 0 0.41608040201005 Nicotinic acetylcholine receptor signaling pathway(P)(0.9992492) 835 DUSP4 8p21.1 0 0 2 27 353 8 402 0.4602 0 0.38391959798995 MAPK signaling pathway(K)(0.9983082)-Oxidative stress response(P)(0.9984262)-Signalling by NGF(R)(0.9987666) 836 GRIN1 9q34.3 0 0 5 0 137 8 737 0.4602 0 0.142713567839196 Alzheimer's disease(K)(0.9986182)-Amyotrophic lateral sclerosis (ALS)(K)(0.9983096)-Calcium signaling pathway(K)(0.9977184)-Huntington disease(P)(0.9990428)-Huntington's disease(K)(0.997862)-Long-term potentiation(K)(0.9950186)-Neuroactive ligand-receptor interaction(K)(0.9989344)-nitric oxide signaling pathway(B)(0.9940556) 837 CH25H 10q23.31 0 0 1 0 141 8 16 0.4602 0 0.142713567839196 Primary bile acid biosynthesis(K)(0.9987076) 838 ABCD1 23q28 0 0 5 6 145 8 216 0.4602 0 0.15678391959799 ABC transporters(K)(0.9969104)-Metabolism of lipids and lipoproteins(R)(0.9985184)-Peroxisome(K)(0.996131)-Transmembrane transport of small molecules(R)(0.9976144) 839 SPOP 17q21.33 0 12 33 1 99 8 63 0.4602 0 0.14572864321608 Signaling events mediated by the Hedgehog family(N)(0.9986818) 840 CDON 11q24.2 0 0 0 11 360 8 63 0.4602 0 0.37286432160804 Signaling events mediated by the Hedgehog family(N)(0.9987022) 841 MS4A1 11q12.2 0 0 3 4 118 8 89 0.4602 0 0.125628140703518 Hematopoietic cell lineage(K)(0.9979458) 842 ITGA2 5q11.2 0 0 1 0 114 8 1117 0.4602 0 0.115577889447236 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9926338)-Dilated cardiomyopathy(K)(0.9951714)-ECM-receptor interaction(K)(0.9939372)-Focal adhesion(K)(0.9977246)-Formation of Platelet plug(R)(0.9987646)-Hematopoietic cell lineage(K)(0.9951098)-Hypertrophic cardiomyopathy (HCM)(K)(0.9942784)-Integrin cell surface interactions(R)(0.9968264)-Integrin signalling pathway(P)(0.9965936)-Pathways in cancer(K)(0.9992456)-Phagosome(K)(0.9977082)-Proteogylcan syndecan-mediated signaling events(N)(0.9973402)-Regulation of actin cytoskeleton(K)(0.9985924)-VEGFR3 signaling in lymphatic endothelium(N)(0.9801768) 843 GFPT2 5q35.3 0 0 5 1 74 8 1135 0.4602 0 0.0804020100502513 Alanine, aspartate and glutamate metabolism(K)(0.9978542)-Amino sugar and nucleotide sugar metabolism(K)(0.9992754)-Metabolic pathways(K)(0.9979748) 844 RPL10 23q28 0 0 7 5 145 8 313 0.4602 0 0.157788944723618 Influenza Life Cycle(R)(0.9977814)-Metabolism of proteins(R)(0.9982486) 845 TAF1 23q13.1 0 0 0 8 166 8 330 0.4602 0 0.174874371859296 Basal transcription factors(K)(0.994357)-Formation and Maturation of mRNA Transcript(R)(0.9989884)-HIV Life Cycle(R)(0.9989024)-Regulation of retinoblastoma protein(N)(0.9982296)-Transcription(R)(0.9956368)-hypoxia and p53 in the cardiovascular system(B)(0.9969262) 846 SMPD2 6q21 0 0 4 6 221 8 1577 0.4602 0 0.232160804020101 Metabolic pathways(K)(0.9981656)-Signalling by NGF(R)(0.9982146)-Sphingolipid metabolism(K)(0.9970656)-TNF receptor signaling pathway(N)(0.9975002)-p75(NTR)-mediated signaling(N)(0.9987978)-phospholipids as signalling intermediaries(B)(0.9977848) 847 PGM3 6q14.2 0 1 1 3 240 8 45 0.4602 0 0.246231155778894 Amino sugar and nucleotide sugar metabolism(K)(0.9994458) 848 AARS 16q22.1 0 0 0 7 471 8 44 0.4602 0 0.480402010050251 Aminoacyl-tRNA biosynthesis(K)(0.9970792)-tRNA Aminoacylation(R)(0.9976066) 849 CAPNS1 19q13.12 0 0 2 1 69 8 134 0.4602 0 0.0723618090452261 Huntington disease(P)(0.99854) 850 TRPM5 11p15.5 0 0 0 0 169 8 52 0.4602 0 0.169849246231156 Taste transduction(K)(0.999315) 851 CITED2 6q24.1 0 0 5 4 190 8 194 0.4602 0 0.2 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9987152)-TGF-beta signaling pathway(P)(0.9976984)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9985582) 852 DCC 18q21.2 0 1 1 1 231 8 440 0.4602 0 0.235175879396985 Axon guidance(K)(0.9986406)-Pathways in cancer(K)(0.9986888) 853 TTC37 5q15 0 0 0 1 144 8 59 0.4602 0 0.14572864321608 RNA degradation(K)(0.998763) 854 DNAH9 17p12 0 0 0 19 456 8 134 0.4602 0 0.477386934673367 Huntington disease(P)(0.9986964) 855 APRT 16q24.3 0 0 2 11 470 8 1190 0.4602 0 0.485427135678392 Metablism of nucleotides(R)(0.9979572)-Metabolic pathways(K)(0.9992884)-Purine metabolism(K)(0.9983948) 856 GADD45B 19p13.3 0 0 1 2 170 8 898 0.4602 0 0.173869346733668 BMP receptor signaling(N)(0.99678)-Cell cycle(K)(0.9979274)-Glypican pathway(N)(0.9986664)-IFN-gamma pathway(N)(0.9971074)-IL12-mediated signaling events(N)(0.9983542)-MAPK signaling pathway(K)(0.9991684)-p53 pathway(P)(0.9900468)-p53 signaling pathway(K)(0.9962212) 857 ECT2 3q26.31 0 1 5 0 19 8 125 0.4602 0 0.0251256281407035 Signaling by Rho GTPases(R)(0.9987868) 858 OR5P3 11p15.4 0 0 2 0 152 8 389 0.4602 0 0.154773869346734 Olfactory transduction(K)(0.998599) 859 EFTUD2 17q21.31 0 0 3 1 206 8 232 0.4602 0 0.21105527638191 Formation and Maturation of mRNA Transcript(R)(0.9995616)-Spliceosome(K)(0.998089) 860 RPL22 1p36.31 0 0 0 3 227 8 313 0.4602 1 0.231155778894472 Influenza Life Cycle(R)(0.9988212)-Metabolism of proteins(R)(0.999496) 861 ITGB3BP 1p31.3 0 1 3 2 149 8 263 0.4602 0 0.155778894472362 M Phase(R)(0.9984346)-Signalling by NGF(R)(0.999617) 862 MMP7 11q22.2 0 1 2 11 330 7 602 0.4602 0 0.34572864321608 Alpha6Beta4Integrin(C)(0.9967622)-Alzheimer disease-presenilin pathway(P)(0.998379)-Wnt signaling pathway(K)(0.9973284)-Wnt signaling pathway(P)(0.9985126)-p75(NTR)-mediated signaling(N)(0.9983276) 863 HADH 4q25 0 0 0 2 112 7 1162 0.4602 0 0.114572864321608 Butanoate metabolism(K)(0.814319)-Fatty acid metabolism(K)(0.9968944)-Lysine degradation(K)(0.9967888)-Metabolic pathways(K)(0.9978632)-Tryptophan metabolism(K)(0.9979294) 864 GNA15 19p13.3 0 0 2 2 165 7 1194 0.4602 0 0.169849246231156 Amoebiasis(K)(0.998526)-Calcium signaling pathway(K)(0.999283)-Chagas disease(K)(0.9970682)-Endothelins(N)(0.99508)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.996727)-LPA receptor mediated events(N)(0.9968764)-Metabotropic glutamate receptor group I pathway(P)(0.9794588)-Opioid Signalling(R)(0.9913454)-Plasma membrane estrogen receptor signaling(N)(0.9984038)-Proteogylcan syndecan-mediated signaling events(N)(0.9986512)-Receptor-ligand complexes bind G proteins(R)(0.996672)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9981114)-Thromboxane A2 receptor signaling(N)(0.9909758)-Wnt signaling pathway(P)(0.9968924)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9944482) 865 LRPAP1 4p16.2 0 0 2 0 140 7 132 0.4602 0 0.142713567839196 Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9988532)-Reelin signaling pathway(N)(0.9985)-Signaling events mediated by the Hedgehog family(N)(0.9986174)-integrin signaling pathway(B)(0.9971692) 866 GADD45A 1p31.3 0 0 0 1 141 7 937 0.4602 0 0.142713567839196 BMP receptor signaling(N)(0.9975148)-Cell cycle(K)(0.9979636)-FoxO family signaling(N)(0.9974178)-Glypican pathway(N)(0.9974246)-IFN-gamma pathway(N)(0.9983336)-MAPK signaling pathway(K)(0.9988498)-PI3 kinase pathway(P)(0.9964104)-Signaling by Aurora kinases(N)(0.9818124)-atm signaling pathway(B)(0.9445562)-cell cycle: g2/m checkpoint(B)(0.9777954)-hypoxia and p53 in the cardiovascular system(B)(0.9951056)-p53 pathway(P)(0.9894804)-p53 signaling pathway(K)(0.9966428) 867 SFI1 22q12.2 0 0 5 2 295 7 83 0.4602 0 0.303517587939699 G2/M Transition(R)(0.9989974) 868 EME1 17q21.33 0 8 23 0 92 7 28 0.4602 0 0.123618090452261 Homologous recombination(K)(0.9985802) 869 OR4C3 11p11.2 0 0 0 3 89 7 413 0.4602 0 0.0924623115577889 Olfactory transduction(K)(0.9991836) 870 IL10RA 11q23.3 0 0 0 12 355 7 370 0.4602 0 0.368844221105528 Cytokine-cytokine receptor interaction(K)(0.9984478)-Interleukin signaling pathway(P)(0.9973692)-Jak-STAT signaling pathway(K)(0.9971984)-il-10 anti-inflammatory signaling pathway(B)(0.99799) 871 NRP1 10p11.22 0 0 1 0 71 7 186 0.4602 0 0.0723618090452261 Axon guidance(K)(0.9990256)-Signaling by VEGF(R)(0.9680412)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.999053) 872 GAS6 13q34 0 0 5 8 237 7 292 0.4602 0 0.251256281407035 Cell surface interactions at the vascular wall(R)(0.9982226)-Metabolism of proteins(R)(0.9984066) 873 CNOT10 3p22.3 0 1 0 1 138 7 59 0.4602 0 0.14070351758794 RNA degradation(K)(0.9991058) 874 PDPR 16q22.1 0 0 0 8 455 7 11 0.4602 0 0.465326633165829 Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9981264) 875 DLL1 6q27 0 0 1 4 215 7 120 0.4602 0 0.221105527638191 NOTCH(C)(0.998926)-Notch signaling pathway(K)(0.9982152)-Presenilin action in Notch and Wnt signaling(N)(0.9986362)-segmentation clock(B)(0.9967732) 876 CLOCK 4q12 0 0 2 0 95 7 30 0.4602 0 0.0974874371859296 Circadian rhythm - mammal(K)(0.9993632)-Circadian rhythm pathway(N)(0.9989054) 877 DNM2 19p13.2 0 0 4 2 83 7 767 0.4602 0 0.0894472361809045 Bacterial invasion of epithelial cells(K)(0.9977358)-Endocytosis(K)(0.9965414)-Fc gamma R-mediated phagocytosis(K)(0.99748)-Gap junction trafficking and regulation(R)(0.991733)-Membrane Trafficking(R)(0.9972902)-Metabolism of nitric oxide(R)(0.9862426)-Nectin adhesion pathway(N)(0.995059)-Plasma membrane estrogen receptor signaling(N)(0.9948324)-Proteogylcan syndecan-mediated signaling events(N)(0.9997968)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9974574) 878 SAT1 23p22.11 0 0 1 10 182 7 1179 0.4602 0 0.193969849246231 Metabolic pathways(K)(0.9984584)-Metabolism of amino acids(R)(0.9977048) 879 DNAJA2 16q12.1 0 0 2 12 417 7 167 0.4602 0 0.433165829145729 Protein processing in endoplasmic reticulum(K)(0.9983124) 880 BECN1 17q21.31 0 1 2 2 205 7 35 0.4602 0 0.21105527638191 Regulation of autophagy(K)(0.9988884) 881 GAD2 10p12.1 0 0 1 0 65 7 1172 0.4602 0 0.0663316582914573 Alanine, aspartate and glutamate metabolism(K)(0.9981798)-Butanoate metabolism(K)(0.8909272)-Metabolic pathways(K)(0.998916)-Type I diabetes mellitus(K)(0.9970454) 882 CYP2E1 10q26.3 0 0 1 1 153 7 1182 0.4602 0 0.155778894472362 Arachidonic acid metabolism(K)(0.9921722)-Biological oxidations(R)(0.9988682)-Drug metabolism - cytochrome P450(K)(0.9971422)-Metabolic pathways(K)(0.9990224)-Metabolism of xenobiotics by cytochrome P450(K)(0.996586)-eicosanoid metabolism(B)(0.9976952) 883 GTF2B 1p22.2 0 0 0 3 176 7 283 0.4602 0 0.179899497487437 Basal transcription factors(K)(0.9971832)-Formation and Maturation of mRNA Transcript(R)(0.9983254)-HIV Life Cycle(R)(0.9956222)-Transcription(R)(0.9988966)-nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells(B)(0.9961718)-the information processing pathway at the ifn beta enhancer(B)(0.9984096) 884 TPTE 21p11.1 0 0 0 2 167 7 90 0.4602 0 0.169849246231156 Hypoxia response via HIF activation(P)(0.9962802)-Insulin/IGF pathway-protein kinase B signaling cascade(P)(0.9963156)-p53 pathway feedback loops 2(P)(0.9987752)-p53 pathway(P)(0.9991786) 885 RBM8A 1q21.1 0 0 20 2 7 7 306 0.4602 0 0.0291457286432161 Formation and Maturation of mRNA Transcript(R)(0.9979306)-Spliceosome(K)(0.999592)-Transcription(R)(0.9970618)-Transport of Mature Transcript to Cytoplasm(R)(0.9935902) 886 HEMK1 3p21.31 0 0 2 1 182 7 75 0.4602 0 0.185929648241206 Histidine metabolism(K)(0.9977602)-Selenoamino acid metabolism(K)(0.9973754)-Tyrosine metabolism(K)(0.9982432) 887 CCNB1 5q13.2 0 0 0 4 133 7 524 0.4602 0 0.137688442211055 Cell Cycle Checkpoints(R)(0.9989986)-Cell cycle(K)(0.995987)-FOXM1 transcription factor network(N)(0.9980954)-FoxO family signaling(N)(0.999319)-G1/S Transition(R)(0.99462)-G2/M Transition(R)(0.99855)-Hedgehog(C)(0.9957818)-Oocyte meiosis(K)(0.998372)-Progesterone-mediated oocyte maturation(K)(0.9959422)-akap95 role in mitosis and chromosome dynamics(B)(0.9924536)-cell cycle: g2/m checkpoint(B)(0.9633464)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.9867066)-how progesterone initiates the oocyte maturation(B)(0.989987)-il-2 receptor beta chain in t cell activation(B)(0.9945544)-p53 signaling pathway(K)(0.9975458)-regulation of cell cycle progression by plk3(B)(0.8967212)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.993767) 888 COL4A1 13q34 0 0 2 5 235 7 655 0.4602 0 0.24321608040201 Amoebiasis(K)(0.9975934)-ECM-receptor interaction(K)(0.9960332)-Focal adhesion(K)(0.9981814)-Integrin cell surface interactions(R)(0.9953736)-Integrin signalling pathway(P)(0.9989894)-Pathways in cancer(K)(0.9993632)-Signaling by PDGF(R)(0.9952676)-intrinsic prothrombin activation pathway(B)(0.9938264)-regulators of bone mineralization(B)(0.9845328) 889 PRKCI 3q26.2 0 0 6 0 31 7 1381 0.4602 0 0.0371859296482412 Alzheimer disease-amyloid secretase pathway(P)(0.9949422)-EGF receptor signaling pathway(P)(0.988321)-EGFR1(C)(0.998839)-Endocytosis(K)(0.9983462)-Endothelin signaling pathway(P)(0.9712258)-FGF signaling pathway(P)(0.9946482)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.995434)-Insulin signaling pathway(K)(0.9980518)-Plasma membrane estrogen receptor signaling(N)(0.9949806)-Proteogylcan syndecan-mediated signaling events(N)(0.9959806)-Signalling by NGF(R)(0.9964044)-TNF receptor signaling pathway(N)(0.9982034)-Tight junction(K)(0.9989334)-Wnt signaling pathway(P)(0.9985484)-p75(NTR)-mediated signaling(N)(0.9931034) 890 CSNK2A1 20p13 0 0 4 4 70 7 1219 0.4602 0 0.078391959798995 Adherens junction(K)(0.997845)-Alpha-synuclein signaling(N)(0.9932448)-BMP receptor signaling(N)(0.994738)-Endothelins(N)(0.9956884)-Glypican pathway(N)(0.9975978)-IFN-gamma pathway(N)(0.9968768)-IL1-mediated signaling events(N)(0.9982462)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9957264)-PDGFR-alpha signaling pathway(N)(0.9893948)-Plasma membrane estrogen receptor signaling(N)(0.9966662)-Presenilin action in Notch and Wnt signaling(N)(0.9963022)-TNF receptor signaling pathway(N)(0.9989196)-TRAIL signaling pathway(N)(0.9950866)-Tight junction(K)(0.9973774)-Wnt signaling pathway(K)(0.9994732)-Wnt signaling pathway(P)(0.9976426)-erk1/erk2 mapk signaling pathway(B)(0.9843458)-growth hormone signaling pathway(B)(0.9946782)-hypoxia and p53 in the cardiovascular system(B)(0.9931842)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9849812)-role of erk5 in neuronal survival pathway(B)(0.991749)-role of ran in mitotic spindle regulation(B)(0.9944874)-tpo signaling pathway(B)(0.9718554) 891 SHC1 1q21.3 0 1 26 0 6 7 1723 0.4602 0 0.0331658291457286 Alpha6Beta4Integrin(C)(0.9921472)-Angiogenesis(P)(0.9911328)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9877692)-Bacterial invasion of epithelial cells(K)(0.9969492)-Cell surface interactions at the vascular wall(R)(0.9991912)-Chemokine signaling pathway(K)(0.9982392)-Chronic myeloid leukemia(K)(0.964741)-EGF receptor signaling pathway(P)(0.9387426)-EGFR1(C)(0.9965334)-Endothelins(N)(0.9940014)-EphrinB-EPHB pathway(N)(0.937)-FGF signaling pathway(P)(0.997272)-Fc-epsilon receptor I signaling in mast cells(N)(0.9677188)-Focal adhesion(K)(0.999347)-Glypican pathway(N)(0.9986556)-IFN-gamma pathway(N)(0.993787)-IL2-mediated signaling events(N)(0.9427872)-Insulin signaling pathway(K)(0.9976292)-Integrin signalling pathway(P)(0.997983)-Interleukin signaling pathway(P)(0.9918118)-Natural killer cell mediated cytotoxicity(K)(0.9985042)-Nectin adhesion pathway(N)(0.9932136)-Neurotrophin signaling pathway(K)(0.9947458)-Plasma membrane estrogen receptor signaling(N)(0.9137174)-Proteogylcan syndecan-mediated signaling events(N)(0.9983192)-Signaling by EGFR(R)(0.9648)-Signaling events mediated by PTP1B(N)(0.9943326)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.992007)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9885874)-Signaling events regulated by Ret tyrosine kinase(N)(0.9897124)-Signalling by NGF(R)(0.997348)-TCR signaling in naive CD4+ T cells(N)(0.9891996)-TRAIL signaling pathway(N)(0.9538798)-a6b1 and a6b4 Integrin signaling(N)(0.9861788)-erk and pi-3 kinase are necessary for collagen binding in corneal epithelia(B)(0.8935994)-il-2 receptor beta chain in t cell activation(B)(0.9868602)-map kinase inactivation of smrt corepressor(B)(0.9810476)-nfat and hypertrophy of the heart (B)(0.9985336)-p75(NTR)-mediated signaling(N)(0.9930794)-role of erbb2 in signal transduction and oncology(B)(0.9869892)-t cell receptor signaling pathway(B)(0.9858362)-the igf-1 receptor and longevity(B)(0.9861296)-tpo signaling pathway(B)(0.9647548) 892 EDNRB 13q22.3 0 0 0 9 260 7 685 0.4602 0 0.27035175879397 Calcium signaling pathway(K)(0.9984936)-Class A/1 (Rhodopsin-like receptors)(R)(0.998045)-Endothelin signaling pathway(P)(0.9955784)-Endothelins(N)(0.998479)-Melanogenesis(K)(0.9971834)-Neuroactive ligand-receptor interaction(K)(0.9994406)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9968786) 893 NR3C1 5q31.3 0 0 0 0 109 7 1056 0.4602 0 0.109547738693467 Androgen-mediated signaling(N)(0.9881036)-AndrogenReceptor(C)(0.996387)-FOXA transcription factor networks(N)(0.9816332)-Glypican pathway(N)(0.9971568)-IFN-gamma pathway(N)(0.9990044)-NR transcription pathway(R)(0.9975312)-Neuroactive ligand-receptor interaction(K)(0.9991224)-Signaling events mediated by HDAC Class I(N)(0.9988056)-corticosteroids and cardioprotection(B)(0.9894606)-nfkb activation by nontypeable hemophilus influenzae(B)(0.9940284)-the information processing pathway at the ifn beta enhancer(B)(0.9957282) 894 DNAJC3 13q32.1 0 0 3 9 244 7 359 0.4602 0 0.257286432160804 Influenza Life Cycle(R)(0.999098)-Protein processing in endoplasmic reticulum(K)(0.998771)-double stranded rna induced gene expression(B)(0.998135) 895 SYNJ2 6q25.3 0 0 2 3 199 7 1159 0.4602 0 0.205025125628141 Inositol phosphate metabolism(K)(0.9946014)-Metabolic pathways(K)(0.9983416)-Phosphatidylinositol signaling system(K)(0.998901)-endocytotic role of ndk phosphins and dynamin(B)(0.9970408) 896 YES1 18p11.32 0 0 1 3 191 7 1243 0.4602 0 0.195979899497487 Adherens junction(K)(0.996256)-Alpha-synuclein signaling(N)(0.990613)-Alpha6Beta4Integrin(C)(0.9925282)-BMP receptor signaling(N)(0.9969608)-Cell surface interactions at the vascular wall(R)(0.9980644)-EphrinB-EPHB pathway(N)(0.976981)-Glypican pathway(N)(0.9986282)-IFN-gamma pathway(N)(0.9980318)-IL1-mediated signaling events(N)(0.994877)-Integrin signalling pathway(P)(0.9989626)-KitReceptor(C)(0.9882528)-Nectin adhesion pathway(N)(0.9933376)-Plasma membrane estrogen receptor signaling(N)(0.9936886)-Proteogylcan syndecan-mediated signaling events(N)(0.9972562)-Signaling events mediated by PTP1B(N)(0.994887)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9949868)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9800532)-TNF receptor signaling pathway(N)(0.9972072)-TRAIL signaling pathway(N)(0.9864866)-Thromboxane A2 receptor signaling(N)(0.990832)-Tight junction(K)(0.9971084) 897 CANX 5q35.3 0 0 2 2 81 7 540 0.4602 0 0.085427135678392 Antigen processing and presentation(K)(0.9990174)-Influenza Life Cycle(R)(0.9972612)-Phagosome(K)(0.998446)-Protein processing in endoplasmic reticulum(K)(0.9978194) 898 DPYD 1p21.3 0 0 2 0 176 7 1138 0.4602 0 0.178894472361809 Drug metabolism - other enzymes(K)(0.9860802)-Metabolic pathways(K)(0.998592)-Pantothenate and CoA biosynthesis(K)(0.9813744)-Pyrimidine metabolism(K)(0.9974832) 899 SETD2 3p21.31 0 0 1 0 201 7 44 0.4602 1 0.203015075376884 Lysine degradation(K)(0.9982548) 900 TNFAIP3 6q23.3 0 1 3 3 186 7 948 0.4602 1 0.193969849246231 Glypican pathway(N)(0.9986418)-IL1-mediated signaling events(N)(0.9919752)-IL12-mediated signaling events(N)(0.9971626)-IL2-mediated signaling events(N)(0.9963594)-IL23-mediated signaling events(N)(0.9929784)-LPA receptor mediated events(N)(0.9976076)-NOD-like receptor signaling pathway(K)(0.9967014)-Signaling by Aurora kinases(N)(0.9689974)-Signaling events regulated by Ret tyrosine kinase(N)(0.9904816)-TCR signaling in naive CD4+ T cells(N)(0.9854044)-TNF alpha/NF-kB(C)(0.9987196)-TNF receptor signaling pathway(N)(0.9944622)-TRAIL signaling pathway(N)(0.9941852)-p75(NTR)-mediated signaling(N)(0.9979524) 901 NCSTN 1q23.2 0 0 20 0 4 7 798 0.4602 0 0.0241206030150754 Alzheimer disease-amyloid secretase pathway(P)(0.9975932)-Alzheimer disease-presenilin pathway(P)(0.9977662)-Alzheimer's disease(K)(0.9977918)-NOTCH(C)(0.9978434)-Notch signaling pathway(K)(0.9972972)-Presenilin action in Notch and Wnt signaling(N)(0.9953536)-Proteogylcan syndecan-mediated signaling events(N)(0.9992842)-Signalling by NGF(R)(0.996638)-p75(NTR)-mediated signaling(N)(0.9987718) 902 RHOT1 17q11.2 0 1 5 3 191 7 125 0.4602 0 0.201005025125628 Signaling by Rho GTPases(R)(0.9987564) 903 PSME3 17q21.31 0 1 2 2 202 7 461 0.4602 0 0.208040201005025 APC/C-mediated degradation of cell cycle proteins(R)(0.9909632)-Antigen processing and presentation(K)(0.9987306)-Apoptosis(R)(0.9989148)-Cell Cycle Checkpoints(R)(0.9955392)-G1/S Transition(R)(0.99263)-Host Interactions of HIV factors(R)(0.9980636)-Metabolism of amino acids(R)(0.9974918)-Proteasome(K)(0.9010246)-S Phase(R)(0.9974966)-Signaling by Wnt(R)(0.9980554) 904 DHX15 4p15.2 0 0 0 2 153 7 128 0.4602 0 0.155778894472362 Spliceosome(K)(0.9992526) 905 MYLK3 16q11.2 0 0 1 11 419 7 625 0.4602 0 0.433165829145729 Calcium signaling pathway(K)(0.9980644)-Focal adhesion(K)(0.9985576)-Gastric acid secretion(K)(0.9974768)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9961036)-Regulation of actin cytoskeleton(K)(0.9983724)-Vascular smooth muscle contraction(K)(0.998411) 906 GAB2 11q14.1 0 30 33 5 141 7 536 0.4602 0 0.210050251256281 Chronic myeloid leukemia(K)(0.9972474)-EGF receptor signaling pathway(P)(0.9981292)-EGFR1(C)(0.9985194)-Fc epsilon RI signaling pathway(K)(0.9980546)-Fc gamma R-mediated phagocytosis(K)(0.998995)-Fc-epsilon receptor I signaling in mast cells(N)(0.9940924)-IL2-mediated signaling events(N)(0.998563)-IL6-mediated signaling events(N)(0.9990276)-TCR signaling in naive CD4+ T cells(N)(0.9980228)-p75(NTR)-mediated signaling(N)(0.9982096) 907 IL6ST 5q11.2 0 0 1 4 133 7 511 0.4602 1 0.138693467336683 AndrogenReceptor(C)(0.9983768)-Cytokine-cytokine receptor interaction(K)(0.9987824)-IL12-mediated signaling events(N)(0.997429)-IL6-mediated signaling events(N)(0.997766)-Interleukin signaling pathway(P)(0.997649)-Jak-STAT signaling pathway(K)(0.997354) 908 CACNA1A 19p13.13 0 0 5 2 117 7 785 0.4602 0 0.124623115577889 Calcium signaling pathway(K)(0.9986338)-Glucose Regulation of Insulin Secretion(R)(0.9987412)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9947288)-Long-term depression(K)(0.9969142)-MAPK signaling pathway(K)(0.9986878)-Synaptic Transmission(R)(0.9978322)-Taste transduction(K)(0.9970766)-Type II diabetes mellitus(K)(0.9966822)-pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase(B)(0.9876788)-rac1 cell motility signaling pathway(B)(0.993423)-rho cell motility signaling pathway(B)(0.995886) 909 TAF6L 11q12.3 0 0 5 2 129 7 36 0.4602 0 0.136683417085427 Basal transcription factors(K)(0.9990708) 910 SPCS1 3p21.1 0 0 0 1 184 7 56 0.4602 0 0.185929648241206 Insulin Synthesis and Secretion(R)(0.9993752)-Protein export(K)(0.9976782) 911 MAP3K8 10p11.23 0 0 0 0 75 7 1075 0.4602 0 0.0753768844221105 BMP receptor signaling(N)(0.9943152)-Endothelins(N)(0.9970944)-Glypican pathway(N)(0.9955368)-IFN-gamma pathway(N)(0.9948988)-IL1-mediated signaling events(N)(0.9912952)-MAPK signaling pathway(K)(0.9995502)-Plasma membrane estrogen receptor signaling(N)(0.9989844)-T cell receptor signaling pathway(K)(0.9978918)-TCR signaling in naive CD4+ T cells(N)(0.9940138)-TNF alpha/NF-kB(C)(0.9995762)-TNF receptor signaling pathway(N)(0.9981662)-TRAIL signaling pathway(N)(0.9942692)-Toll-like receptor signaling pathway(K)(0.9970508)-mapkinase signaling pathway(B)(0.9933368) 912 MED12 23q13.1 0 0 2 8 170 7 33 0.4602 1 0.180904522613065 Generic Transcription Pathway(R)(0.9982554) 913 ATP5G1 17q21.32 0 6 17 1 134 7 1338 0.4602 0 0.158793969849246 Alzheimer's disease(K)(0.9974912)-Glucose Regulation of Insulin Secretion(R)(0.9970178)-Huntington's disease(K)(0.9986218)-Metablism of nucleotides(R)(0.9922788)-Metabolic pathways(K)(0.998779)-Oxidative phosphorylation(K)(0.9969766)-Parkinson's disease(K)(0.997654) 914 POLA1 23p22.11 0 0 1 6 144 7 1321 0.4602 0 0.151758793969849 DNA replication(K)(0.9938104)-G1/S Transition(R)(0.9963684)-Metabolic pathways(K)(0.9989942)-Purine metabolism(K)(0.9983872)-Pyrimidine metabolism(K)(0.9908528)-S Phase(R)(0.9963692)-Telomere Maintenance(R)(0.9976068) 915 TMOD1 9q22.33 0 0 0 2 154 7 31 0.4602 0 0.15678391959799 Muscle contraction(R)(0.9980772) 916 ACSL5 10q25.2 0 0 0 1 140 7 1259 0.4602 0 0.141708542713568 Adipocytokine signaling pathway(K)(0.9981854)-Metabolic pathways(K)(0.9984786)-PPAR signaling pathway(K)(0.9977682)-Peroxisome(K)(0.9975382) 917 MED16 19p13.3 0 0 3 1 207 7 33 0.4602 0 0.212060301507538 Generic Transcription Pathway(R)(0.9983748) 918 SLC17A5 6q13 0 0 0 5 238 7 121 0.4602 0 0.244221105527638 Lysosome(K)(0.9993116) 919 ERO1L 14q22.1 0 0 12 0 129 7 249 0.4602 0 0.141708542713568 Insulin Synthesis and Secretion(R)(0.9976614)-Protein processing in endoplasmic reticulum(K)(0.9985192)-Vibrio cholerae infection(K)(0.9971676) 920 ERCC8 5q12.1 0 0 0 1 152 7 225 0.4602 0 0.153768844221106 DNA Repair(R)(0.9981414)-Nucleotide excision repair(K)(0.9951354)-Ubiquitin mediated proteolysis(K)(0.9987688) 921 APOA5 11q23.3 0 0 0 13 365 7 153 0.4602 0 0.379899497487437 Metabolism of lipids and lipoproteins(R)(0.999243)-PPAR signaling pathway(K)(0.9983296) 922 SERPINA1 14q32.13 0 0 0 2 167 7 240 0.4602 0 0.169849246231156 Complement and coagulation cascades(K)(0.9994462)-FOXA transcription factor networks(N)(0.9908812)-Formation of Platelet plug(R)(0.9982676) 923 PARS2 1p32.3 0 0 2 1 142 7 41 0.4602 0 0.14572864321608 Aminoacyl-tRNA biosynthesis(K)(0.9990196) 924 DHRS3 1p36.21 0 0 0 1 213 7 1130 0.4602 0 0.215075376884422 Metabolic pathways(K)(0.9987594)-Retinol metabolism(K)(0.9989352) 925 PRSS2 7q34 0 0 4 0 85 7 367 0.4602 0 0.0894472361809045 Neuroactive ligand-receptor interaction(K)(0.997927)-Pancreatic secretion(K)(0.9975758) 926 CD276 15q24.1 0 2 2 0 132 7 135 0.4602 0 0.136683417085427 Cell adhesion molecules (CAMs)(K)(0.9987912) 927 MAG 19q13.12 0 0 2 0 48 7 463 0.4602 0 0.050251256281407 Cell adhesion molecules (CAMs)(K)(0.999325)-Cell surface interactions at the vascular wall(R)(0.9980522)-Signalling by NGF(R)(0.9984962)-p75(NTR)-mediated signaling(N)(0.9983232) 928 CCNE2 8q22.1 0 1 52 0 11 7 663 0.4602 0 0.064321608040201 Cell Cycle Checkpoints(R)(0.9910308)-Cell cycle(K)(0.993382)-G1/S Transition(R)(0.983487)-Oocyte meiosis(K)(0.9997928)-Parkinson disease(P)(0.9989702)-Pathways in cancer(K)(0.999163)-Prostate cancer(K)(0.9974796)-S Phase(R)(0.8919686)-p53 signaling pathway(K)(0.9971976) 929 LATS2 13q12.11 0 0 0 9 268 7 125 0.4602 0 0.278391959798995 Androgen-mediated signaling(N)(0.9932898) 930 H2BFWT 23q22.2 0 0 1 6 170 7 139 0.4602 0 0.177889447236181 Systemic lupus erythematosus(K)(0.9983462) 931 TRIM24 7q34 0 0 5 3 98 7 125 0.4602 0 0.106532663316583 Androgen-mediated signaling(N)(0.9942078) 932 ARHGEF3 3p14.3 0 0 0 0 198 7 125 0.4602 0 0.198994974874372 Signaling by Rho GTPases(R)(0.998815) 933 PPIL2 22q11.21 0 0 3 1 274 7 232 0.4602 0 0.279396984924623 Cell surface interactions at the vascular wall(R)(0.9979702)-Ubiquitin mediated proteolysis(K)(0.9986188) 934 RPLP2 11p15.5 0 0 2 1 163 7 313 0.4602 0 0.166834170854271 Influenza Life Cycle(R)(0.9988944)-Metabolism of proteins(R)(0.998388) 935 CENPI 23q22.1 0 0 1 11 199 7 96 0.4602 0 0.212060301507538 M Phase(R)(0.99812) 936 OR8A1 11q24.2 0 0 0 10 357 7 389 0.4602 0 0.368844221105528 Olfactory transduction(K)(0.99918) 937 MBTPS2 23p22.12 0 0 2 5 142 7 167 0.4602 0 0.149748743718593 Protein processing in endoplasmic reticulum(K)(0.9991348) 938 VPS45 1q21.2 0 2 17 0 8 7 204 0.4602 0 0.0271356783919598 Endocytosis(K)(0.9985644) 939 TCF4 18q21.2 0 0 2 1 202 6 599 0.496 0 0.206030150753769 Androgen-mediated signaling(N)(0.9900024)-Glypican pathway(N)(0.9987278)-Wnt(C)(0.9982434) 940 GLUD1 10q23.2 0 0 1 1 138 6 1211 0.496 0 0.14070351758794 Alanine, aspartate and glutamate metabolism(K)(0.9973236)-Metabolic pathways(K)(0.9987072)-Metabolism of amino acids(R)(0.9979304)-Nitrogen metabolism(K)(0.9963182)-Proximal tubule bicarbonate reclamation(K)(0.996595) 941 ABL1 9q34.12 0 0 3 0 173 6 1128 0.496 1 0.176884422110553 Alpha6Beta4Integrin(C)(0.9888368)-Axon guidance(K)(0.9992066)-Cell cycle(K)(0.998769)-ErbB signaling pathway(K)(0.9937204)-Integrin signalling pathway(P)(0.998167)-KitReceptor(C)(0.9938222)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9927024)-Nectin adhesion pathway(N)(0.996442)-Neurotrophin signaling pathway(K)(0.9980558)-Pathogenic Escherichia coli infection(K)(0.9959302)-Pathways in cancer(K)(0.9980078)-Regulation of Telomerase(N)(0.9963518)-Regulation of retinoblastoma protein(N)(0.9954792)-Shigellosis(K)(0.9963754)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9986134)-Viral myocarditis(K)(0.9964348)-p75(NTR)-mediated signaling(N)(0.9979974)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.984057) 942 PAPSS1 4q25 0 0 1 2 108 6 1199 0.496 0 0.111557788944724 Metabolic pathways(K)(0.9989034)-Purine metabolism(K)(0.9992382)-Selenoamino acid metabolism(K)(0.9949428)-Sulfur metabolism(K)(0.9962488) 943 UROD 1p34.1 0 0 0 0 142 6 47 0.496 0 0.142713567839196 Porphyrin and chlorophyll metabolism(K)(0.9992918)-hemoglobins chaperone(B)(0.9948336) 944 ITGA9 3p22.2 0 0 1 0 138 6 636 0.496 0 0.139698492462312 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9940566)-Cell adhesion molecules (CAMs)(K)(0.9979008)-Dilated cardiomyopathy(K)(0.9938892)-ECM-receptor interaction(K)(0.996525)-Focal adhesion(K)(0.9974022)-Hypertrophic cardiomyopathy (HCM)(K)(0.996834)-Integrin cell surface interactions(R)(0.9981254)-Integrin signalling pathway(P)(0.998327)-Regulation of actin cytoskeleton(K)(0.9991308) 945 CLDN10 13q32.1 0 0 3 11 269 6 298 0.496 0 0.284422110552764 Cell adhesion molecules (CAMs)(K)(0.997069)-Leukocyte transendothelial migration(K)(0.9975596)-Tight junction(K)(0.9987782) 946 CHST7 23p11.3 0 0 0 6 158 6 22 0.496 0 0.164824120603015 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9983898) 947 POMT1 9q34.13 0 0 2 0 156 6 3 0.496 0 0.158793969849246 O-Mannosyl glycan biosynthesis(K)(0.99592)