rank gene gband SNV.Indel HLAMP AMP HOMD HETD covered_events node_degree p.value CGC.status percentage.event as.character(p.way) 1 TP53 17p13.1 35 0 0 1 33 3632 1976 0 1 0.818181818181818 Amyotrophic lateral sclerosis (ALS)(K)(0.9956158)-Apoptosis(K)(0.9898764)-BARD1 signaling events(N)(0.9936592)-BMP receptor signaling(N)(0.9921944)-Cell Cycle Checkpoints(R)(0.9947236)-Cell cycle(K)(0.9945336)-Glypican pathway(N)(0.992422)-Huntington disease(P)(0.9970084)-Huntington's disease(K)(0.999277)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9981064)-IFN-gamma pathway(N)(0.9983606)-IL1-mediated signaling events(N)(0.9848798)-MAPK signaling pathway(K)(0.9989188)-Neurotrophin signaling pathway(K)(0.9945484)-Pathways in cancer(K)(0.9977392)-Plasma membrane estrogen receptor signaling(N)(0.9950044)-Prostate cancer(K)(0.9886354)-Signaling by Aurora kinases(N)(0.9563832)-Signaling events mediated by HDAC Class I(N)(0.9987856)-TGFBR(C)(0.9943236)-TNF receptor signaling pathway(N)(0.9958436)-Wnt signaling pathway(K)(0.9941194)-Wnt signaling pathway(P)(0.9989158)-double stranded rna induced gene expression(B)(0.8625876)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.973104)-hypoxia and p53 in the cardiovascular system(B)(0.9791378)-overview of telomerase protein component gene htert transcriptional regulation(B)(0.9680906)-p53 pathway by glucose deprivation(P)(0.9663)-p53 signaling pathway(K)(0.995131)-p75(NTR)-mediated signaling(N)(0.9961584)-regulation of transcriptional activity by pml(B)(0.9505598)-telomeres telomerase cellular aging and immortality(B)(0.9852746)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9866386) 2 PLCB2 15q15.1 0 0 0 2 34 2090 2547 0 0 0.545454545454545 Alpha-synuclein signaling(N)(0.9896498)-Alzheimer's disease(K)(0.99806)-Amoebiasis(K)(0.9972832)-Calcium signaling pathway(K)(0.9987206)-Chagas disease(K)(0.9950024)-Chemokine signaling pathway(K)(0.997299)-Endothelin signaling pathway(P)(0.9839806)-Endothelins(N)(0.9778854)-Gap junction(K)(0.996785)-Gastric acid secretion(K)(0.994127)-GnRH signaling pathway(K)(0.9913878)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9975224)-Huntington's disease(K)(0.9975794)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.995899)-Long-term depression(K)(0.9894348)-Long-term potentiation(K)(0.977372)-Metabolic pathways(K)(0.9979044)-Pancreatic secretion(K)(0.9933208)-Plasma membrane estrogen receptor signaling(N)(0.998237)-Salivary secretion(K)(0.9928916)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9986134)-Taste transduction(K)(0.995682)-Thromboxane A2 receptor signaling(N)(0.9786424)-Vascular smooth muscle contraction(K)(0.994608)-Wnt signaling pathway(K)(0.9964668)-Wnt signaling pathway(P)(0.9979124) 3 PIK3R1 5q13.1 2 0 0 4 30 1146 2377 0 1 0.53030303030303 Aldosterone-regulated sodium reabsorption(K)(0.9949016)-Alpha6Beta4Integrin(C)(0.9926966)-Amoebiasis(K)(0.9925826)-Androgen-mediated signaling(N)(0.9468722)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9422026)-Apoptosis(K)(0.9916958)-B cell receptor signaling pathway(K)(0.9858266)-Cell surface interactions at the vascular wall(R)(0.9979302)-Chemokine signaling pathway(K)(0.9969596)-EGFR1(C)(0.9968442)-Endothelins(N)(0.9833434)-EphrinB-EPHB pathway(N)(0.957579)-ErbB signaling pathway(K)(0.907271)-Fc gamma R-mediated phagocytosis(K)(0.9815526)-Fc-epsilon receptor I signaling in mast cells(N)(0.979292)-Glypican pathway(N)(0.9977986)-Hypoxia response via HIF activation(P)(0.896575)-IL12-mediated signaling events(N)(0.9912976)-IL2-mediated signaling events(N)(0.935915)-IL23-mediated signaling events(N)(0.9556282)-IL6-mediated signaling events(N)(0.982412)-Insulin signaling pathway(K)(0.9961566)-Integrin signalling pathway(P)(0.9927582)-Integrins in angiogenesis(N)(0.969687)-Jak-STAT signaling pathway(K)(0.9981008)-LPA receptor mediated events(N)(0.9867656)-Leukocyte transendothelial migration(K)(0.9965162)-NOTCH(C)(0.997378)-Natural killer cell mediated cytotoxicity(K)(0.99437)-Nectin adhesion pathway(N)(0.9942592)-Neurotrophin signaling pathway(K)(0.9537196)-Pathways in cancer(K)(0.9992812)-Phosphatidylinositol signaling system(K)(0.9980028)-Progesterone-mediated oocyte maturation(K)(0.987689)-Prostate cancer(K)(0.9578572)-Proteogylcan syndecan-mediated signaling events(N)(0.9985688)-Reelin signaling pathway(N)(0.9958648)-Regulation of actin cytoskeleton(K)(0.9994838)-Signaling by Aurora kinases(N)(0.9754038)-Signaling by EGFR(R)(0.8626354)-Signaling by PDGF(R)(0.9227368)-Signaling events mediated by PTP1B(N)(0.9376514)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9419458)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.8915204)-Signaling events mediated by the Hedgehog family(N)(0.9954886)-Signaling events regulated by Ret tyrosine kinase(N)(0.9875128)-Signalling by NGF(R)(0.9981902)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8958864)-TCR signaling in naive CD4+ T cells(N)(0.988322)-TGFBR(C)(0.9963618)-TNF receptor signaling pathway(N)(0.9711484)-Toll-like receptor signaling pathway(K)(0.9945532)-Type II diabetes mellitus(K)(0.9930416)-a6b1 and a6b4 Integrin signaling(N)(0.9046024)-actions of nitric oxide in the heart(B)(0.989648)-b cell survival pathway(B)(0.9749116)-control of skeletal myogenesis by hdac and calcium/calmodulin-dependent kinase (camk)(B)(0.9096526)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.8459842)-mTOR signaling pathway(K)(0.9826278)-nfat and hypertrophy of the heart (B)(0.985984)-p75(NTR)-mediated signaling(N)(0.9946634)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.9803626)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9793094)-thrombin signaling and protease-activated receptors(B)(0.872002)-trefoil factors initiate mucosal healing(B)(0.9609408)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9713048) 4 POLR2A 17p13.1 0 0 0 1 32 762 1654 0 0 0.5 DNA Repair(R)(0.9964962)-Formation and Maturation of mRNA Transcript(R)(0.9971676)-HIV Life Cycle(R)(0.996909)-Huntington's disease(K)(0.9983684)-Influenza Life Cycle(R)(0.994073)-Metabolic pathways(K)(0.9984712)-Purine metabolism(K)(0.9987724)-Pyrimidine metabolism(K)(0.9937084)-Regulatory RNA pathways(R)(0.9725588)-Transcription(R)(0.998079)-mRNA Processing(R)(0.9961566)-repression of pain sensation by the transcriptional regulator dream(B)(0.9929752)-telomeres telomerase cellular aging and immortality(B)(0.9961538) 5 PRKX 23p22.33 0 0 0 8 31 637 1639 0 0 0.590909090909091 Amoebiasis(K)(0.9977336)-Apoptosis(K)(0.9983796)-Calcium signaling pathway(K)(0.9982922)-Chemokine signaling pathway(K)(0.9993828)-Gap junction(K)(0.9967028)-Gastric acid secretion(K)(0.995768)-GnRH signaling pathway(K)(0.9924932)-Hedgehog signaling pathway(K)(0.9958646)-Insulin signaling pathway(K)(0.99602)-Long-term potentiation(K)(0.98217)-MAPK signaling pathway(K)(0.9983028)-Melanogenesis(K)(0.9836784)-Metabotropic glutamate receptor group I pathway(P)(0.9599542)-Olfactory transduction(K)(0.9990634)-Oocyte meiosis(K)(0.9961986)-Prion diseases(K)(0.9915708)-Progesterone-mediated oocyte maturation(K)(0.9898536)-Salivary secretion(K)(0.998107)-Taste transduction(K)(0.9961372)-Vascular smooth muscle contraction(K)(0.9961054)-Vasopressin-regulated water reabsorption(K)(0.9973582)-Vibrio cholerae infection(K)(0.991981)-Wnt signaling pathway(K)(0.9962452) 6 AKT1 14q32.33 0 0 0 0 31 443 2455 0 1 0.46969696969697 Adipocytokine signaling pathway(K)(0.993396)-Alpha6Beta4Integrin(C)(0.9912188)-Androgen-mediated signaling(N)(0.9556552)-AndrogenReceptor(C)(0.9945254)-Angiogenesis(P)(0.9381702)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9250712)-Apoptosis signaling pathway(P)(0.94511)-Apoptosis(K)(0.9826658)-Apoptosis(R)(0.9985142)-B cell receptor signaling pathway(K)(0.9818958)-Chemokine signaling pathway(K)(0.9969516)-EGFR1(C)(0.997321)-Endothelin signaling pathway(P)(0.98239)-Endothelins(N)(0.909341)-ErbB signaling pathway(K)(0.8724774)-FAS signaling pathway(P)(0.869045)-FOXA transcription factor networks(N)(0.9542442)-Fc gamma R-mediated phagocytosis(K)(0.9924306)-Fc-epsilon receptor I signaling in mast cells(N)(0.9692316)-Focal adhesion(K)(0.9962616)-FoxO family signaling(N)(0.9863964)-Glypican pathway(N)(0.996115)-Huntington disease(P)(0.9979252)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.992314)-IL2-mediated signaling events(N)(0.907985)-IL6-mediated signaling events(N)(0.9738816)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9918338)-Insulin signaling pathway(K)(0.9969488)-Integrins in angiogenesis(N)(0.986597)-Jak-STAT signaling pathway(K)(0.9961166)-MAPK signaling pathway(K)(0.9958318)-Metabolism of nitric oxide(R)(0.9613928)-Nectin adhesion pathway(N)(0.9905072)-Neurotrophin signaling pathway(K)(0.9606282)-Pathways in cancer(K)(0.998502)-Plasma membrane estrogen receptor signaling(N)(0.9368728)-Progesterone-mediated oocyte maturation(K)(0.9961038)-Prostate cancer(K)(0.974448)-Proteogylcan syndecan-mediated signaling events(N)(0.9913798)-Reelin signaling pathway(N)(0.984159)-Regulation of Telomerase(N)(0.9956178)-Regulation of beta-cell development(R)(0.9941676)-Retinoic acid receptors-mediated signaling(N)(0.913564)-Signaling events mediated by PTP1B(N)(0.9239356)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9336122)-Signaling events mediated by the Hedgehog family(N)(0.9905346)-Signalling by NGF(R)(0.9965274)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8000442)-TCR signaling in naive CD4+ T cells(N)(0.988293)-TNF alpha/NF-kB(C)(0.9980446)-TNF receptor signaling pathway(N)(0.9935198)-Thromboxane A2 receptor signaling(N)(0.9884358)-Tight junction(K)(0.998326)-Toll-like receptor signaling pathway(K)(0.9920688)-Wnt(C)(0.996682)-hypoxia and p53 in the cardiovascular system(B)(0.9789884)-mTOR signaling pathway(K)(0.9842508)-p53 pathway(P)(0.9874922)-p75(NTR)-mediated signaling(N)(0.993216)-regulation of eif2(B)(0.9818006) 7 HSPA2 14q23.3 0 0 0 0 31 414 827 2e-04 0 0.46969696969697 Antigen processing and presentation(K)(0.9959188)-Endocytosis(K)(0.999136)-MAPK signaling pathway(K)(0.9987884)-Parkinson disease(P)(0.9986462)-Protein processing in endoplasmic reticulum(K)(0.9984466)-Spliceosome(K)(0.9967946) 8 CTSG 14q12 1 0 0 0 25 332 633 0.0073 0 0.393939393939394 Amoebiasis(K)(0.995105)-Lysosome(K)(0.9981634)-Neuroactive ligand-receptor interaction(K)(0.9987736)-Renin-angiotensin system(K)(0.9947884)-Systemic lupus erythematosus(K)(0.9983308) 9 NOS2 17q11.1 0 0 0 0 32 322 2370 0.0102 0 0.484848484848485 Amoebiasis(K)(0.9975286)-BMP receptor signaling(N)(0.991726)-Calcium signaling pathway(K)(0.9979644)-Chagas disease(K)(0.9953374)-Glypican pathway(N)(0.9932074)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9988758)-IL1-mediated signaling events(N)(0.9882894)-IL12-mediated signaling events(N)(0.9973682)-IL23-mediated signaling events(N)(0.9944054)-Leishmaniasis(K)(0.9926148)-Metabolic pathways(K)(0.99863)-Pathways in cancer(K)(0.9976246)-Peroxisome(K)(0.9979906)-Plasma membrane estrogen receptor signaling(N)(0.9974624)-TNF receptor signaling pathway(N)(0.9971304)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.995106) 10 HRAS 11p15.5 0 0 0 1 26 252 2199 0.0726 1 0.409090909090909 Axon guidance(K)(0.9987876)-B cell receptor signaling pathway(K)(0.988743)-Cell surface interactions at the vascular wall(R)(0.9981404)-Chemokine signaling pathway(K)(0.9980676)-EGF receptor signaling pathway(P)(0.9601434)-EGFR1(C)(0.9965904)-Endocytosis(K)(0.9992614)-Endothelins(N)(0.9879434)-ErbB signaling pathway(K)(0.9910504)-Fc epsilon RI signaling pathway(K)(0.8362976)-Focal adhesion(K)(0.9937074)-Gap junction(K)(0.9945968)-Glypican pathway(N)(0.987459)-IL2 signaling events mediated by PI3K(N)(0.8785194)-Insulin signaling pathway(K)(0.9982586)-Integrin signalling pathway(P)(0.993421)-KitReceptor(C)(0.827993)-LPA receptor mediated events(N)(0.9919954)-Long-term depression(K)(0.9874076)-Long-term potentiation(K)(0.9732204)-MAPK signaling pathway(K)(0.9972376)-Natural killer cell mediated cytotoxicity(K)(0.995801)-Nectin adhesion pathway(N)(0.9871128)-Pathways in cancer(K)(0.9979994)-Prostate cancer(K)(0.8560856)-Proteogylcan syndecan-mediated signaling events(N)(0.9989546)-Regulation of actin cytoskeleton(K)(0.9990956)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.984685)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9354572)-Signaling events regulated by Ret tyrosine kinase(N)(0.9654974)-Signalling by NGF(R)(0.9964556)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9917718)-TCR signaling in naive CD4+ T cells(N)(0.9888034)-TRAIL signaling pathway(N)(0.9956652)-Tight junction(K)(0.9971668)-a6b1 and a6b4 Integrin signaling(N)(0.977787)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9439826)-how progesterone initiates the oocyte maturation(B)(0.8802308)-map kinase inactivation of smrt corepressor(B)(0.9082502)-mcalpain and friends in cell motility(B)(0.8560098)-mets affect on macrophage differentiation(B)(0.9911532)-nfat and hypertrophy of the heart (B)(0.9962916)-p38 mapk signaling pathway(B)(0.9335166)-p75(NTR)-mediated signaling(N)(0.9900466)-t cell receptor signaling pathway(B)(0.864147)-the igf-1 receptor and longevity(B)(0.8663516)-tpo signaling pathway(B)(0.9665352)-trefoil factors initiate mucosal healing(B)(0.9913608) 11 CCNH 5q14.3 0 0 0 3 32 248 668 0.0729 0 0.53030303030303 AndrogenReceptor(C)(0.996765)-Cell cycle(K)(0.9963822)-DNA Repair(R)(0.998807)-Formation and Maturation of mRNA Transcript(R)(0.9995284)-G1/S Transition(R)(0.9960458)-G2/M Transition(R)(0.9990514)-HIV Life Cycle(R)(0.994447)-Nucleotide excision repair(K)(0.9902902)-Retinoic acid receptors-mediated signaling(N)(0.9972264)-Transcription(R)(0.9988498)-il-2 receptor beta chain in t cell activation(B)(0.9973404)-mRNA Processing(R)(0.9807488) 12 PIGH 14q24.1 0 0 0 0 36 207 1304 0.1549 0 0.545454545454545 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis(K)(0.9709594)-Metabolic pathways(K)(0.9991724)-Metabolism of proteins(R)(0.9987956) 13 RHOA 3p21.31 0 0 1 0 30 189 2226 0.1943 0 0.46969696969697 Adherens junction(K)(0.9845936)-Alpha6Beta4Integrin(C)(0.9824802)-Angiogenesis(P)(0.974371)-Axon guidance(K)(0.9988502)-Chemokine signaling pathway(K)(0.9972938)-EPO signaling pathway(N)(0.9429886)-Endocytosis(K)(0.9974072)-Focal adhesion(K)(0.9858074)-Glypican pathway(N)(0.9982026)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.993245)-IL2-mediated signaling events(N)(0.9811988)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9927294)-Integrin signalling pathway(P)(0.9903726)-Integrins in angiogenesis(N)(0.9151044)-LPA receptor mediated events(N)(0.992501)-Leukocyte transendothelial migration(K)(0.9841652)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9937546)-Neurotrophin signaling pathway(K)(0.9976694)-Pancreatic secretion(K)(0.9970482)-Pathogenic Escherichia coli infection(K)(0.9493034)-Pathways in cancer(K)(0.9988864)-Plasma membrane estrogen receptor signaling(N)(0.9298672)-Proteogylcan syndecan-mediated signaling events(N)(0.9976594)-Regulation of actin cytoskeleton(K)(0.991176)-Signaling by Aurora kinases(N)(0.9855854)-Signaling by Rho GTPases(R)(0.9977912)-Signaling events mediated by PRL(N)(0.987506)-Signaling events mediated by PTP1B(N)(0.9931664)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.94283)-Signaling events regulated by Ret tyrosine kinase(N)(0.9883804)-Signalling by NGF(R)(0.996202)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8610258)-TGF-beta signaling pathway(K)(0.9941396)-TRAIL signaling pathway(N)(0.9962488)-Thromboxane A2 receptor signaling(N)(0.8542226)-Tight junction(K)(0.9985608)-Vascular smooth muscle contraction(K)(0.9942746)-Wnt signaling pathway(K)(0.9957836)-Wnt(C)(0.9973068)-amb2 Integrin signaling(N)(0.9923584)-integrin signaling pathway(B)(0.9339796)-p75(NTR)-mediated signaling(N)(0.9894182)-protein kinase a at the centrosome(B)(0.9478212)-thrombin signaling and protease-activated receptors(B)(0.8362714)-trefoil factors initiate mucosal healing(B)(0.9869812) 14 VAMP2 17p13.1 0 0 0 1 36 181 817 0.2058 0 0.560606060606061 5HT2 type receptor mediated signaling pathway(P)(0.9944396)-Glucose Regulation of Insulin Secretion(R)(0.9984792)-Insulin Synthesis and Secretion(R)(0.9984238)-Membrane Trafficking(R)(0.9954482)-Plasma membrane estrogen receptor signaling(N)(0.9969276)-Proteogylcan syndecan-mediated signaling events(N)(0.9983598)-SNARE interactions in vesicular transport(K)(0.9950964)-Salivary secretion(K)(0.9987976)-Synaptic Transmission(R)(0.9975194)-Synaptic_vesicle_trafficking(P)(0.9596432)-Vasopressin-regulated water reabsorption(K)(0.9965564) 15 ECHS1 10q26.3 0 0 0 0 29 153 1281 0.292 0 0.439393939393939 Fatty acid metabolism(K)(0.9282242)-Lysine degradation(K)(0.9983962)-Metabolic pathways(K)(0.998791)-Metabolism of amino acids(R)(0.9985874)-Metabolism of lipids and lipoproteins(R)(0.9988708)-Tryptophan metabolism(K)(0.997685) 16 CCL5 17q12 0 0 0 0 36 142 914 0.3165 0 0.545454545454545 Chagas disease(K)(0.995864)-Chemokine signaling pathway(K)(0.999074)-Class A/1 (Rhodopsin-like receptors)(R)(0.998959)-Cytokine-cytokine receptor interaction(K)(0.9980154)-Cytosolic DNA-sensing pathway(K)(0.9962452)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9959386)-NOD-like receptor signaling pathway(K)(0.997546)-Prion diseases(K)(0.9925908)-Proteogylcan syndecan-mediated signaling events(N)(0.9985688)-Receptor-ligand complexes bind G proteins(R)(0.9868684)-Toll-like receptor signaling pathway(K)(0.9938206) 17 CREBBP 16p13.3 1 0 0 0 28 134 2270 0.3165 1 0.439393939393939 Adherens junction(K)(0.9948088)-Androgen-mediated signaling(N)(0.9467898)-AndrogenReceptor(C)(0.9953274)-BMP receptor signaling(N)(0.9587074)-Cell cycle(K)(0.9948952)-Endothelins(N)(0.9839464)-FOXA transcription factor networks(N)(0.9638806)-FOXM1 transcription factor network(N)(0.9777324)-FoxO family signaling(N)(0.980227)-Generic Transcription Pathway(R)(0.9910254)-Glypican pathway(N)(0.923908)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9983356)-Huntington disease(P)(0.9977258)-Huntington's disease(K)(0.9980654)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9896212)-IFN-gamma pathway(N)(0.9885144)-IL1-mediated signaling events(N)(0.992967)-Jak-STAT signaling pathway(K)(0.9951234)-Long-term potentiation(K)(0.9897754)-Melanogenesis(K)(0.9707864)-Notch signaling pathway(K)(0.99801)-Pathways in cancer(K)(0.9975346)-Plasma membrane estrogen receptor signaling(N)(0.9558814)-Prostate cancer(K)(0.983473)-Regulation of retinoblastoma protein(N)(0.9936084)-Renal cell carcinoma(K)(0.8864992)-Retinoic acid receptors-mediated signaling(N)(0.9722878)-Signaling events mediated by HDAC Class I(N)(0.9947212)-Signaling events mediated by the Hedgehog family(N)(0.9839542)-TGF-beta signaling pathway(K)(0.9883478)-TGF-beta signaling pathway(P)(0.9935904)-TGFBR(C)(0.9939932)-TNF alpha/NF-kB(C)(0.9988522)-TNF receptor signaling pathway(N)(0.8438892)-TRAIL signaling pathway(N)(0.942389)-Wnt signaling pathway(K)(0.994817)-Wnt signaling pathway(P)(0.9974976)-carm1 and regulation of the estrogen receptor(B)(0.9358336)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.988674) 18 OR10P1 12q13.2 0 0 0 0 24 134 413 0.3165 0 0.363636363636364 Olfactory Signaling Pathway(R)(0.9986482)-Olfactory transduction(K)(0.9968704) 19 CRK 17p13.3 0 0 0 1 37 126 1575 0.332 0 0.575757575757576 Angiogenesis(P)(0.98655)-Angiopoietin receptor Tie2-mediated signaling(N)(0.985158)-Bacterial invasion of epithelial cells(K)(0.8605026)-Chemokine signaling pathway(K)(0.9991036)-EGFR1(C)(0.9976872)-Endothelins(N)(0.9925812)-EphrinB-EPHB pathway(N)(0.9503746)-ErbB signaling pathway(K)(0.9910348)-Fc gamma R-mediated phagocytosis(K)(0.9948382)-Focal adhesion(K)(0.9961208)-Formation of Platelet plug(R)(0.9968182)-Insulin signaling pathway(K)(0.9992862)-Integrin cell surface interactions(R)(0.9960814)-Integrin signalling pathway(P)(0.9966872)-KitReceptor(C)(0.9862496)-LPA receptor mediated events(N)(0.98206)-MAPK signaling pathway(K)(0.9975512)-Nectin adhesion pathway(N)(0.9917514)-Neurotrophin signaling pathway(K)(0.9947214)-Pathways in cancer(K)(0.9987108)-Plasma membrane estrogen receptor signaling(N)(0.995008)-Proteogylcan syndecan-mediated signaling events(N)(0.9986392)-Regulation of actin cytoskeleton(K)(0.9980216)-Shigellosis(K)(0.9687202)-Signaling by PDGF(R)(0.956342)-Signaling events mediated by PTP1B(N)(0.991935)-Signaling events regulated by Ret tyrosine kinase(N)(0.9929102)-Signalling by NGF(R)(0.9992358)-TCR signaling in naive CD4+ T cells(N)(0.9960132)-p75(NTR)-mediated signaling(N)(0.9964262) 20 ACOX3 4p16.1 0 0 0 1 31 115 1269 0.3631 0 0.484848484848485 Biosynthesis of unsaturated fatty acids(K)(0.997091)-Metabolic pathways(K)(0.998932)-Metabolism of lipids and lipoproteins(R)(0.9992958)-PPAR signaling pathway(K)(0.9977016)-Peroxisome(K)(0.9976164) 21 MAP3K1 5q11.2 0 0 0 6 30 111 1308 0.3643 0 0.545454545454545 BMP receptor signaling(N)(0.9968336)-Endothelins(N)(0.9914156)-FAS signaling pathway (CD95)(N)(0.8768448)-Fc-epsilon receptor I signaling in mast cells(N)(0.9929398)-Glypican pathway(N)(0.9989854)-GnRH signaling pathway(K)(0.9957756)-IFN-gamma pathway(N)(0.9769382)-IL1-mediated signaling events(N)(0.9903218)-Integrins in angiogenesis(N)(0.9969194)-MAPK signaling pathway(K)(0.9979204)-Neurotrophin signaling pathway(K)(0.9984834)-Plasma membrane estrogen receptor signaling(N)(0.9988206)-RIG-I-like receptor signaling pathway(K)(0.9975816)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9350624)-TCR signaling in naive CD4+ T cells(N)(0.9937662)-TNF receptor signaling pathway(N)(0.9901136)-TRAIL signaling pathway(N)(0.998996)-Ubiquitin mediated proteolysis(K)(0.9981506)-keratinocyte differentiation(B)(0.9606994)-lectin induced complement pathway(B)(0.9889134)-map kinase inactivation of smrt corepressor(B)(0.9885342)-mapkinase signaling pathway(B)(0.9829778)-p38 mapk signaling pathway(B)(0.984837)-rac1 cell motility signaling pathway(B)(0.9909486)-role of mal in rho-mediated activation of srf(B)(0.9771048)-toll-like receptor pathway(B)(0.9925016) 22 NR3C1 5q31.3 3 0 0 1 27 103 1056 0.3864 0 0.454545454545455 Androgen-mediated signaling(N)(0.985853)-AndrogenReceptor(C)(0.997611)-FOXA transcription factor networks(N)(0.9837094)-Glypican pathway(N)(0.9949276)-IFN-gamma pathway(N)(0.998029)-NR transcription pathway(R)(0.9985002)-Neuroactive ligand-receptor interaction(K)(0.9984936)-Signaling events mediated by HDAC Class I(N)(0.9984248)-corticosteroids and cardioprotection(B)(0.991962)-nfkb activation by nontypeable hemophilus influenzae(B)(0.9952286)-the information processing pathway at the ifn beta enhancer(B)(0.990786) 23 CD40LG 23q26.3 0 0 1 5 19 95 1409 0.4112 0 0.378787878787879 Asthma(K)(0.9881766)-B cell receptor signaling pathway(K)(0.8340694)-BMP receptor signaling(N)(0.996015)-Cell adhesion molecules (CAMs)(K)(0.998131)-Cytokine-cytokine receptor interaction(K)(0.9983618)-Endothelins(N)(0.9833206)-Glypican pathway(N)(0.9948494)-Graft-versus-host disease(K)(0.9942732)-IFN-gamma pathway(N)(0.996044)-IL1-mediated signaling events(N)(0.9884944)-Malaria(K)(0.997862)-Plasma membrane estrogen receptor signaling(N)(0.9968146)-Primary immunodeficiency(K)(0.9957382)-Systemic lupus erythematosus(K)(0.997327)-T cell receptor signaling pathway(K)(0.9935402)-TCR signaling in naive CD4+ T cells(N)(0.9957696)-TNF receptor signaling pathway(N)(0.993531)-TRAIL signaling pathway(N)(0.960999)-Viral myocarditis(K)(0.9954468) 24 HSPA8 11q24.1 1 0 0 0 25 85 1264 0.417 0 0.393939393939394 Antigen processing and presentation(K)(0.9933448)-Endocytosis(K)(0.9989624)-Glypican pathway(N)(0.997252)-IFN-gamma pathway(N)(0.9961314)-MAPK signaling pathway(K)(0.9981542)-Membrane Trafficking(R)(0.9908838)-Parkinson disease(P)(0.9957608)-Protein processing in endoplasmic reticulum(K)(0.99665)-Spliceosome(K)(0.9978162)-TGFBR(C)(0.9978676) 25 TTC37 5q15 1 0 0 3 35 83 59 0.417 0 0.575757575757576 RNA degradation(K)(0.9975824) 26 POLR2L 11p15.5 0 0 0 1 28 81 1755 0.417 0 0.439393939393939 DNA Repair(R)(0.9985146)-Formation and Maturation of mRNA Transcript(R)(0.9979254)-HIV Life Cycle(R)(0.9001742)-Huntington's disease(K)(0.9979162)-Influenza Life Cycle(R)(0.9954268)-Metabolic pathways(K)(0.998152)-Purine metabolism(K)(0.997022)-Pyrimidine metabolism(K)(0.9947952)-Regulatory RNA pathways(R)(0.989402)-TNF alpha/NF-kB(C)(0.9985958)-Transcription(R)(0.9975302)-mRNA Processing(R)(0.990708) 27 ARRB2 17p13.2 0 0 0 1 33 81 2176 0.417 0 0.515151515151515 Chemokine signaling pathway(K)(0.9988084)-Endocytosis(K)(0.998939)-Glypican pathway(N)(0.991043)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9979818)-IFN-gamma pathway(N)(0.9979622)-IL1-mediated signaling events(N)(0.9892626)-IL12-mediated signaling events(N)(0.9953048)-IL2-mediated signaling events(N)(0.9371254)-IL23-mediated signaling events(N)(0.9719258)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9938178)-LPA receptor mediated events(N)(0.9859484)-MAPK signaling pathway(K)(0.999126)-Olfactory transduction(K)(0.999067)-Phototransduction(K)(0.9851176)-Plasma membrane estrogen receptor signaling(N)(0.9737676)-Proteogylcan syndecan-mediated signaling events(N)(0.9977136)-Signaling by Aurora kinases(N)(0.988863)-Signaling events mediated by the Hedgehog family(N)(0.9972192)-Signaling events regulated by Ret tyrosine kinase(N)(0.9864976)-TCR signaling in naive CD4+ T cells(N)(0.984716)-TGFBR(C)(0.99574)-TNF receptor signaling pathway(N)(0.9862724)-TRAIL signaling pathway(N)(0.9961252)-Thromboxane A2 receptor signaling(N)(0.9899106)-Wnt signaling pathway(P)(0.9988256)-Wnt(C)(0.9945328)-p75(NTR)-mediated signaling(N)(0.9966442) 28 PAFAH1B1 17p13.3 0 0 0 1 39 77 1328 0.4251 0 0.606060606060606 Ether lipid metabolism(K)(0.9771624)-G2/M Transition(R)(0.998475)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.995857)-M Phase(R)(0.9980992)-Metabolic pathways(K)(0.9988468)-Reelin signaling pathway(N)(0.9969064) 29 MYH8 17p13.1 1 0 0 1 35 73 513 0.4346 0 0.560606060606061 Muscle contraction(R)(0.997629)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9974346)-Tight junction(K)(0.9992874)-Viral myocarditis(K)(0.9987342)-Wnt signaling pathway(P)(0.9983796) 30 TUBB4Q 4q35.2 0 0 0 4 29 68 557 0.4382 0 0.5 Gap junction(K)(0.9978268)-Huntington disease(P)(0.9978298)-Metabolism of proteins(R)(0.9977134)-Pathogenic Escherichia coli infection(K)(0.9976344)-Phagosome(K)(0.993459) 31 EPHX2 8p21.1 0 0 0 2 39 66 1176 0.4382 0 0.621212121212121 Arachidonic acid metabolism(K)(0.9982312)-Metabolic pathways(K)(0.9991558)-Peroxisome(K)(0.9970316) 32 PCSK1 5q15 0 0 0 4 34 61 207 0.4382 0 0.575757575757576 Alzheimer disease-amyloid secretase pathway(P)(0.9984604)-Alzheimer disease-presenilin pathway(P)(0.9974126)-Insulin Synthesis and Secretion(R)(0.9976858) 33 ATP6V0A1 17q21.31 0 0 0 0 34 59 1416 0.4382 0 0.515151515151515 Collecting duct acid secretion(K)(0.9949268)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9984804)-Lysosome(K)(0.999538)-Metabolic pathways(K)(0.997708)-Oxidative phosphorylation(K)(0.9974872)-Phagosome(K)(0.998154)-Vibrio cholerae infection(K)(0.9980852) 34 HARS2 NA 0 0 0 2 31 58 44 0.4382 0 0.5 Aminoacyl-tRNA biosynthesis(K)(0.9989964)-tRNA Aminoacylation(R)(0.9953866) 35 PIK3CA 3q26.32 7 0 1 0 1 57 2397 0.4382 1 0.136363636363636 Aldosterone-regulated sodium reabsorption(K)(0.9928152)-Alpha6Beta4Integrin(C)(0.8684062)-Amoebiasis(K)(0.9983806)-Angiopoietin receptor Tie2-mediated signaling(N)(0.8604796)-Cell surface interactions at the vascular wall(R)(0.993529)-Chemokine signaling pathway(K)(0.8168548)-EGFR1(C)(0.9954374)-ErbB signaling pathway(K)(0.9772282)-FGF signaling pathway(P)(0.867071)-Fc gamma R-mediated phagocytosis(K)(0.9680902)-IL6-mediated signaling events(N)(0.9958008)-Insulin signaling pathway(K)(0.9919176)-Integrin signalling pathway(P)(0.9888866)-Integrins in angiogenesis(N)(0.9315418)-Jak-STAT signaling pathway(K)(0.9689322)-LPA receptor mediated events(N)(0.8095084)-Natural killer cell mediated cytotoxicity(K)(0.996815)-Nectin adhesion pathway(N)(0.952742)-Pathways in cancer(K)(0.9983856)-Phosphatidylinositol signaling system(K)(0.9957658)-Progesterone-mediated oocyte maturation(K)(0.9273316)-Proteogylcan syndecan-mediated signaling events(N)(0.994737)-Reelin signaling pathway(N)(0.993607)-Regulation of actin cytoskeleton(K)(0.9965934)-Signaling by Aurora kinases(N)(0.939328)-Signaling events mediated by the Hedgehog family(N)(0.9673052)-Signaling events regulated by Ret tyrosine kinase(N)(0.9737456)-Signalling by NGF(R)(0.993687)-Toll-like receptor signaling pathway(K)(0.9857632)-Type II diabetes mellitus(K)(0.9943982)-actions of nitric oxide in the heart(B)(0.9937868)-nfat and hypertrophy of the heart (B)(0.9928596)-p75(NTR)-mediated signaling(N)(0.9953036)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.9643344)-trefoil factors initiate mucosal healing(B)(0.8787218) 36 ABCC8 11p15.1 0 0 0 1 22 55 292 0.4382 0 0.348484848484849 ABC transporters(K)(0.9984008)-FOXA transcription factor networks(N)(0.9880144)-Glucose Regulation of Insulin Secretion(R)(0.9989592)-Type II diabetes mellitus(K)(0.9985916) 37 ALDH3A2 17p11.2 0 0 1 1 37 54 1184 0.4382 0 0.590909090909091 Fatty acid metabolism(K)(0.9970718)-Histidine metabolism(K)(0.9954446)-Lysine degradation(K)(0.9988904)-Metabolic pathways(K)(0.9974186)-Pyruvate metabolism(K)(0.9974618) 38 UBE2G1 17p13.2 0 0 0 1 36 54 408 0.4382 0 0.560606060606061 Parkinson's disease(K)(0.9986496)-Protein processing in endoplasmic reticulum(K)(0.998163)-Ubiquitin mediated proteolysis(K)(0.9988412) 39 HTR2C 23q23 0 0 0 6 21 50 650 0.4557 0 0.409090909090909 Calcium signaling pathway(K)(0.998396)-Class A/1 (Rhodopsin-like receptors)(R)(0.997617)-Gap junction(K)(0.9970588)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9965586)-Neuroactive ligand-receptor interaction(K)(0.999482)-Receptor-ligand complexes bind G proteins(R)(0.9915822)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9904972)-chrebp regulation by carbohydrates and camp(B)(0.9950968)-ion channels and their functional role in vascular endothelium(B)(0.9956784)-ß-arrestins in gpcr desensitization(B)(0.9934014) 40 ABR 17p13.3 0 0 0 1 40 49 125 0.4557 0 0.621212121212121 Signaling by Rho GTPases(R)(0.9995854) 41 CALM1 14q32.11 0 0 0 0 30 47 2001 0.4588 0 0.454545454545455 Alzheimer's disease(K)(0.9963554)-BMP receptor signaling(N)(0.9927784)-Calcium signaling pathway(K)(0.9978046)-Further platelet releasate(R)(0.9904464)-Gastric acid secretion(K)(0.9959692)-Glypican pathway(N)(0.9965852)-GnRH signaling pathway(K)(0.97984)-IFN-gamma pathway(N)(0.9977728)-IL1-mediated signaling events(N)(0.983742)-IL2-mediated signaling events(N)(0.984892)-Insulin signaling pathway(K)(0.9965468)-Long-term potentiation(K)(0.9832082)-Melanogenesis(K)(0.9917076)-Metabolism of carbohydrates(R)(0.9991028)-Metabolism of nitric oxide(R)(0.9919992)-Neurotrophin signaling pathway(K)(0.9937658)-Olfactory transduction(K)(0.99949)-Oocyte meiosis(K)(0.9966594)-Opioid Signalling(R)(0.982271)-Phosphatidylinositol signaling system(K)(0.9961122)-Phototransduction(K)(0.8021366)-Plasma membrane estrogen receptor signaling(N)(0.9960692)-Salivary secretion(K)(0.990614)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.991478)-Signalling by NGF(R)(0.9954216)-TCR signaling in naive CD4+ T cells(N)(0.986613)-TNF receptor signaling pathway(N)(0.989929)-TRAIL signaling pathway(N)(0.9873156)-VEGF signaling pathway(K)(0.9553506)-Vascular smooth muscle contraction(K)(0.9924978) 42 RAD50 5q31.1 0 0 0 2 33 46 187 0.4588 0 0.53030303030303 BARD1 signaling events(N)(0.997916)-DNA Repair(R)(0.9975218)-Homologous recombination(K)(0.9943584)-Non-homologous end-joining(K)(0.9688492)-Regulation of Telomerase(N)(0.998156)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9962404) 43 MAOA 23p11.3 0 0 0 6 26 44 1213 0.4662 0 0.484848484848485 Biological oxidations(R)(0.9973836)-Drug metabolism - cytochrome P450(K)(0.9969962)-Glycine, serine and threonine metabolism(K)(0.9939942)-Histidine metabolism(K)(0.994684)-Metabolic pathways(K)(0.9989534)-Synaptic Transmission(R)(0.9973) 44 SNRPD3 22q11.23 0 0 1 0 17 43 502 0.4662 0 0.272727272727273 Formation and Maturation of mRNA Transcript(R)(0.9982384)-Influenza Life Cycle(R)(0.9989408)-Metabolism of non-coding RNA(R)(0.9939808)-Spliceosome(K)(0.9974046)-Systemic lupus erythematosus(K)(0.9977378) 45 CSF2RA 23p22.33 0 0 0 9 35 41 644 0.4771 0 0.666666666666667 Cytokine-cytokine receptor interaction(K)(0.9988372)-Hematopoietic cell lineage(K)(0.9986264)-Jak-STAT signaling pathway(K)(0.995512)-Pathways in cancer(K)(0.9996572) 46 TRPV1 17p13.3 0 0 0 1 37 37 444 0.4771 0 0.575757575757576 Neuroactive ligand-receptor interaction(K)(0.998399)-p75(NTR)-mediated signaling(N)(0.9990254) 47 TAF1 23q13.1 2 0 0 6 25 37 330 0.4771 0 0.5 Basal transcription factors(K)(0.9942426)-Formation and Maturation of mRNA Transcript(R)(0.9986988)-HIV Life Cycle(R)(0.9991272)-Regulation of retinoblastoma protein(N)(0.9973748)-Transcription(R)(0.9985638)-hypoxia and p53 in the cardiovascular system(B)(0.9910954) 48 CASP3 4q35.1 0 0 0 3 27 36 1908 0.4771 0 0.454545454545455 Alpha6Beta4Integrin(C)(0.9898448)-Alzheimer's disease(K)(0.9967972)-Amoebiasis(K)(0.9968458)-Amyotrophic lateral sclerosis (ALS)(K)(0.9944056)-Apoptosis signaling pathway(P)(0.9884604)-Apoptosis(K)(0.9740932)-Apoptosis(R)(0.9963682)-BMP receptor signaling(N)(0.9905312)-Endothelins(N)(0.9898054)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9977954)-FAS signaling pathway (CD95)(N)(0.9550568)-FAS signaling pathway(P)(0.9893208)-Glypican pathway(N)(0.8838178)-Huntington disease(P)(0.9980898)-Huntington's disease(K)(0.9973718)-IFN-gamma pathway(N)(0.97327)-IL1-mediated signaling events(N)(0.9883366)-LPA receptor mediated events(N)(0.9512296)-MAPK signaling pathway(K)(0.998688)-Natural killer cell mediated cytotoxicity(K)(0.998035)-Parkinson's disease(K)(0.995403)-Pathways in cancer(K)(0.9987422)-Plasma membrane estrogen receptor signaling(N)(0.9811774)-Proteogylcan syndecan-mediated signaling events(N)(0.9514646)-Signalling by NGF(R)(0.998724)-TNF alpha/NF-kB(C)(0.9976758)-TNF receptor signaling pathway(N)(0.9685366)-Viral myocarditis(K)(0.9918956)-a6b1 and a6b4 Integrin signaling(N)(0.8363934)-b cell survival pathway(B)(0.9849966)-granzyme a mediated apoptosis pathway(B)(0.969252)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.962127)-internal ribosome entry pathway(B)(0.9475814)-p53 signaling pathway(K)(0.995958)-p75(NTR)-mediated signaling(N)(0.9892084)-trefoil factors initiate mucosal healing(B)(0.9147008) 49 HEXB 5q13.3 0 0 0 4 32 35 1228 0.4771 0 0.545454545454545 Amino sugar and nucleotide sugar metabolism(K)(0.998559)-Lysosome(K)(0.9982446)-Metabolic pathways(K)(0.9986906)-Other glycan degradation(K)(0.9964898) 50 RPA1 17p13.3 0 0 0 1 37 35 298 0.4771 0 0.575757575757576 Cell Cycle Checkpoints(R)(0.9976156)-DNA Repair(R)(0.9991616)-DNA replication(K)(0.9916296)-G1/S Transition(R)(0.910708)-Homologous recombination(K)(0.9988062)-Mismatch repair(K)(0.9932132)-Nucleotide excision repair(K)(0.995871)-S Phase(R)(0.9965606)-Telomere Maintenance(R)(0.9983312)-atm signaling pathway(B)(0.989122)-hypoxia and p53 in the cardiovascular system(B)(0.9972104) 51 PLA2G4E 15q15.1 0 0 0 1 41 35 1647 0.4771 0 0.636363636363636 Arachidonic acid metabolism(K)(0.9947168)-Ether lipid metabolism(K)(0.9758574)-Fc epsilon RI signaling pathway(K)(0.9866418)-Fc gamma R-mediated phagocytosis(K)(0.9973276)-Glycerophospholipid metabolism(K)(0.997695)-GnRH signaling pathway(K)(0.9976158)-Long-term depression(K)(0.997859)-MAPK signaling pathway(K)(0.9964036)-Metabolic pathways(K)(0.9992894)-Pancreatic secretion(K)(0.9985114)-VEGF signaling pathway(K)(0.9972964)-Vascular smooth muscle contraction(K)(0.997098) 52 OR4F17 19p13.3 0 0 1 2 32 35 413 0.4771 0 0.53030303030303 Olfactory Signaling Pathway(R)(0.9979394)-Olfactory transduction(K)(0.9990008) 53 RANBP2 2q13 1 0 0 0 11 33 608 0.4855 0 0.181818181818182 HIV Life Cycle(R)(0.9971822)-Host Interactions of HIV factors(R)(0.9993212)-Influenza Life Cycle(R)(0.9981286)-M Phase(R)(0.9982452)-Metabolism of carbohydrates(R)(0.9975528)-Metabolism of non-coding RNA(R)(0.9954264)-Signaling events mediated by HDAC Class I(N)(0.9986296)-Transport of Mature Transcript to Cytoplasm(R)(0.9919754) 54 PVRL1 11q23.3 0 0 0 1 27 33 383 0.4855 0 0.424242424242424 Adherens junction(K)(0.9961868)-Alzheimer disease-presenilin pathway(P)(0.9983812)-Cell adhesion molecules (CAMs)(K)(0.9989246)-Nectin adhesion pathway(N)(0.9985452) 55 NOTCH1 9q34.3 1 0 0 0 22 30 376 0.5193 1 0.348484848484849 Alzheimer disease-presenilin pathway(P)(0.998789)-Angiogenesis(P)(0.9970192)-Dorso-ventral axis formation(K)(0.9966506)-Generic Transcription Pathway(R)(0.9852746)-NOTCH(C)(0.997735)-Notch signaling pathway(K)(0.9975238)-Presenilin action in Notch and Wnt signaling(N)(0.9836768)-Prion diseases(K)(0.9946188)-Regulation of beta-cell development(R)(0.9974304) 56 UGT1A8 2q37.1 3 0 0 0 14 29 1192 0.5231 0 0.257575757575758 Metabolic pathways(K)(0.9991284)-Metabolism of xenobiotics by cytochrome P450(K)(0.9983346)-Porphyrin and chlorophyll metabolism(K)(0.998099)-Retinol metabolism(K)(0.9975192)-Starch and sucrose metabolism(K)(0.9961498)-Steroid hormone biosynthesis(K)(0.9859574) 57 GP1BA 17p13.2 0 0 0 1 35 28 300 0.5231 0 0.545454545454545 ECM-receptor interaction(K)(0.998233)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.995174)-Formation of Platelet plug(R)(0.9991026)-Hematopoietic cell lineage(K)(0.9989272)-amb2 Integrin signaling(N)(0.9935478) 58 INS 11p15.5 0 0 0 1 30 27 1454 0.5231 0 0.46969696969697 Aldosterone-regulated sodium reabsorption(K)(0.9952422)-Endothelins(N)(0.99025)-FOXA transcription factor networks(N)(0.964231)-Glucose Regulation of Insulin Secretion(R)(0.997612)-Glypican pathway(N)(0.9930236)-IFN-gamma pathway(N)(0.9963326)-Insulin Synthesis and Secretion(R)(0.998453)-Insulin signaling pathway(K)(0.996719)-Oocyte meiosis(K)(0.997612)-PI3 kinase pathway(P)(0.9843048)-Progesterone-mediated oocyte maturation(K)(0.986707)-Prostate cancer(K)(0.990441)-Proteogylcan syndecan-mediated signaling events(N)(0.9975762)-Regulation of actin cytoskeleton(K)(0.998399)-Regulation of autophagy(K)(0.9989804)-Regulation of beta-cell development(R)(0.970945)-Signaling by Insulin receptor(R)(0.9710058)-Signaling events mediated by PTP1B(N)(0.9928664)-TRAIL signaling pathway(N)(0.9963926)-Type I diabetes mellitus(K)(0.9959714)-Type II diabetes mellitus(K)(0.9568626)-mTOR signaling pathway(K)(0.9920426) 59 BTRC 10q24.32 0 0 0 0 23 27 975 0.5231 0 0.348484848484849 Circadian rhythm - mammal(K)(0.9941502)-Hedgehog signaling pathway(K)(0.9953252)-Host Interactions of HIV factors(R)(0.9983352)-Oocyte meiosis(K)(0.9975234)-Shigellosis(K)(0.997391)-TGFBR(C)(0.9977838)-TNF alpha/NF-kB(C)(0.9981624)-Ubiquitin mediated proteolysis(K)(0.99853)-Wnt signaling pathway(K)(0.9914096)-Wnt signaling pathway(P)(0.9974504)-Wnt(C)(0.996782)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9838244) 60 PLD1 3q26.31 1 0 2 0 1 26 2094 0.5231 0 0.0606060606060606 Alpha-synuclein signaling(N)(0.8334654)-Calcineurin-regulated NFAT-dependent transcription in lymphocytes(N)(0.9067672)-EGFR1(C)(0.805338)-Endocytosis(K)(0.9928762)-Glycerophospholipid metabolism(K)(0.890862)-Metabolic pathways(K)(0.9930698)-Pathways in cancer(K)(0.9916874)-Proteogylcan syndecan-mediated signaling events(N)(0.9930394) 61 NRAS 1p13.2 2 0 0 0 14 25 1923 0.5231 1 0.242424242424242 Angiogenesis(P)(0.989682)-Axon guidance(K)(0.9992758)-Cell surface interactions at the vascular wall(R)(0.9976398)-Chemokine signaling pathway(K)(0.9945972)-EGFR1(C)(0.9949588)-EphrinB-EPHB pathway(N)(0.9280638)-ErbB signaling pathway(K)(0.8864218)-FGF signaling pathway(P)(0.9859808)-Gap junction(K)(0.9974886)-Glypican pathway(N)(0.9970116)-IL2-mediated signaling events(N)(0.8559032)-Insulin signaling pathway(K)(0.9969734)-Integrin signalling pathway(P)(0.99574)-Interleukin signaling pathway(P)(0.9925816)-Long-term potentiation(K)(0.9922122)-MAPK signaling pathway(K)(0.9990524)-Natural killer cell mediated cytotoxicity(K)(0.9972918)-Neurotrophin signaling pathway(K)(0.9846058)-Pathways in cancer(K)(0.9984694)-Plasma membrane estrogen receptor signaling(N)(0.91908)-Regulation of actin cytoskeleton(K)(0.9985122)-Signaling by EGFR(R)(0.9775948)-Signaling by PDGF(R)(0.9876304)-Signalling by NGF(R)(0.9934732)-TRAIL signaling pathway(N)(0.8602314)-Tight junction(K)(0.9979238)-p75(NTR)-mediated signaling(N)(0.9961966) 62 PRPF8 17p13.3 0 0 0 1 37 25 232 0.5231 0 0.575757575757576 Formation and Maturation of mRNA Transcript(R)(0.9955564)-Spliceosome(K)(0.9992572) 63 BMPR1B 4q22.3 0 0 0 0 20 24 816 0.5231 0 0.303030303030303 BMP receptor signaling(N)(0.9983524)-Cytokine-cytokine receptor interaction(K)(0.998171)-Signaling by BMP(R)(0.9938468)-TGF-beta signaling pathway(K)(0.9970592)-TGF-beta signaling pathway(P)(0.9978644)-Wnt signaling pathway(P)(0.9983584) 64 HS3ST3A1 17p12 0 0 0 1 36 24 26 0.5231 0 0.560606060606061 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9992282) 65 CDH1 16q22.1 2 0 1 1 21 23 1411 0.5231 1 0.363636363636364 Adherens junction(K)(0.9945522)-Alzheimer disease-presenilin pathway(P)(0.9972194)-Apoptosis(R)(0.9980798)-Bacterial invasion of epithelial cells(K)(0.99154)-Cell adhesion molecules (CAMs)(K)(0.998126)-Integrin cell surface interactions(R)(0.9949506)-Melanoma(K)(0.9729288)-Nectin adhesion pathway(N)(0.8261624)-Pathogenic Escherichia coli infection(K)(0.9933928)-Pathways in cancer(K)(0.999133)-Plasma membrane estrogen receptor signaling(N)(0.9988394)-Proteogylcan syndecan-mediated signaling events(N)(0.992958)-Wnt signaling pathway(P)(0.9982142)-Wnt(C)(0.9972598)-a6b1 and a6b4 Integrin signaling(N)(0.951241)-downregulated of mta-3 in er-negative breast tumors(B)(0.9897728)-tgf beta signaling pathway(B)(0.9952854) 66 SNAP23 15q15.1 0 0 0 2 38 22 106 0.5231 0 0.606060606060606 5HT2 type receptor mediated signaling pathway(P)(0.997043)-Membrane Trafficking(R)(0.9987414)-PNAT(P)(0.9955178)-SNARE interactions in vesicular transport(K)(0.9980826) 67 RPL26 17p13.1 0 0 0 1 39 22 313 0.5231 0 0.606060606060606 Influenza Life Cycle(R)(0.9975034)-Metabolism of proteins(R)(0.998884)-Ribosome(K)(0.9974146) 68 ALDH7A1 5q23.2 0 0 0 1 34 21 1188 0.5231 0 0.53030303030303 Fatty acid metabolism(K)(0.9981222)-Glycine, serine and threonine metabolism(K)(0.9948834)-Histidine metabolism(K)(0.991784)-Lysine degradation(K)(0.9985676)-Metabolic pathways(K)(0.9989058)-Pyruvate metabolism(K)(0.9974554)-Tryptophan metabolism(K)(0.994952) 69 CHUK 10q24.2 0 0 0 0 22 21 1719 0.5231 0 0.333333333333333 Adipocytokine signaling pathway(K)(0.9984206)-Apoptosis signaling pathway(P)(0.9761786)-Apoptosis(K)(0.9918108)-B cell receptor signaling pathway(K)(0.9910928)-Chagas disease(K)(0.9854816)-Chemokine signaling pathway(K)(0.997031)-Cytosolic DNA-sensing pathway(K)(0.99781)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9987534)-FAS signaling pathway (CD95)(N)(0.9722622)-Fc-epsilon receptor I signaling in mast cells(N)(0.9507442)-Glypican pathway(N)(0.8800372)-IL12-mediated signaling events(N)(0.9974176)-IL2-mediated signaling events(N)(0.9801432)-IL23-mediated signaling events(N)(0.8861282)-Integrins in angiogenesis(N)(0.9935188)-Interleukin signaling pathway(P)(0.9797924)-LPA receptor mediated events(N)(0.996329)-MAPK signaling pathway(K)(0.9974058)-NOD-like receptor signaling pathway(K)(0.995107)-Pathways in cancer(K)(0.9984452)-Prostate cancer(K)(0.990178)-RIG-I-like receptor signaling pathway(K)(0.996768)-Shigellosis(K)(0.9976472)-Signaling by Aurora kinases(N)(0.9652712)-Signaling events regulated by Ret tyrosine kinase(N)(0.9925594)-Signalling by NGF(R)(0.9992196)-T cell receptor signaling pathway(K)(0.9911324)-TCR signaling in naive CD4+ T cells(N)(0.995926)-TCR signaling(R)(0.9798658)-TNF alpha/NF-kB(C)(0.9985042)-TRAIL signaling pathway(N)(0.8969002)-Toll-like receptor signaling pathway(K)(0.9722412)-double stranded rna induced gene expression(B)(0.9412774)-lectin induced complement pathway(B)(0.9642844)-p75(NTR)-mediated signaling(N)(0.99694)-trefoil factors initiate mucosal healing(B)(0.9118516) 70 ABCD1 23q28 0 0 1 1 24 21 216 0.5231 0 0.393939393939394 ABC transporters(K)(0.9969866)-Metabolism of lipids and lipoproteins(R)(0.9987624)-Peroxisome(K)(0.9977084)-Transmembrane transport of small molecules(R)(0.9941186) 71 TGFB3 14q24.3 0 0 0 0 32 21 1395 0.5231 0 0.484848484848485 Amoebiasis(K)(0.9975812)-Cell cycle(K)(0.9987658)-Chagas disease(K)(0.9968204)-Cytokine-cytokine receptor interaction(K)(0.999446)-Dilated cardiomyopathy(K)(0.9909716)-Endocytosis(K)(0.9990898)-Formation of Platelet plug(R)(0.998281)-Hypertrophic cardiomyopathy (HCM)(K)(0.997018)-Leishmaniasis(K)(0.9938812)-MAPK signaling pathway(K)(0.9990592)-Malaria(K)(0.9969426)-Pathways in cancer(K)(0.9979396)-Renal cell carcinoma(K)(0.9979742)-TGF-beta signaling pathway(K)(0.997526)-TGF-beta signaling pathway(P)(0.9949056)-TGFBR(C)(0.9978802)-alk in cardiac myocytes(B)(0.9856546)-ctcf: first multivalent nuclear factor(B)(0.9867666)-tgf beta signaling pathway(B)(0.9914316) 72 RRM1 11p15.4 1 0 0 2 28 21 1222 0.5231 0 0.46969696969697 Glutathione metabolism(K)(0.997132)-Metablism of nucleotides(R)(0.8888138)-Metabolic pathways(K)(0.999093)-Purine metabolism(K)(0.9988206)-Pyrimidine metabolism(K)(0.9962696) 73 NCOR1 17p11.2 1 0 0 1 35 20 772 0.5231 0 0.560606060606061 Glypican pathway(N)(0.9990146)-Huntington disease(P)(0.9987932)-IFN-gamma pathway(N)(0.9975634)-NOTCH(C)(0.9989296)-NR transcription pathway(R)(0.9969088)-Signaling events mediated by HDAC Class I(N)(0.9987294)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.996736) 74 ELK1 23p11.23 0 0 1 6 23 20 1404 0.5231 0 0.454545454545455 Angiopoietin receptor Tie2-mediated signaling(N)(0.9912278)-EGFR1(C)(0.9969954)-Endometrial cancer(K)(0.9831184)-ErbB signaling pathway(K)(0.9978318)-Focal adhesion(K)(0.998207)-Glypican pathway(N)(0.9949674)-GnRH signaling pathway(K)(0.9862372)-ID(C)(0.994254)-Insulin signaling pathway(K)(0.9962736)-Leishmaniasis(K)(0.9867688)-MAPK signaling pathway(K)(0.9989338)-Oxidative stress response(P)(0.9899204)-Parkinson disease(P)(0.9983552)-Prion diseases(K)(0.985631)-Proteogylcan syndecan-mediated signaling events(N)(0.9985458)-Signalling by NGF(R)(0.9971782)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9971778)-TCR signaling in naive CD4+ T cells(N)(0.9950398)-TRAIL signaling pathway(N)(0.996673)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9911518)-p38 mapk signaling pathway(B)(0.9882994)-p75(NTR)-mediated signaling(N)(0.9961008)-t cell receptor signaling pathway(B)(0.9936478)-toll-like receptor pathway(B)(0.9929014)-tpo signaling pathway(B)(0.976135) 75 CSNK1E 22q13.1 0 0 0 0 16 19 569 0.5231 0 0.242424242424242 Circadian rhythm - mammal(K)(0.9938228)-Circadian rhythm pathway(N)(0.9943282)-FoxO family signaling(N)(0.9971688)-G2/M Transition(R)(0.997563)-Hedgehog signaling pathway(K)(0.9689776)-Signaling events mediated by the Hedgehog family(N)(0.993099)-Wnt signaling pathway(K)(0.9975224)-Wnt signaling pathway(P)(0.9986754)-Wnt(C)(0.9961046) 76 TAF9 5q13.2 1 0 0 3 29 19 254 0.5231 0 0.5 Basal transcription factors(K)(0.9969322)-Formation and Maturation of mRNA Transcript(R)(0.9982042)-HIV Life Cycle(R)(0.9979792)-Transcription(R)(0.9981426) 77 DRD2 11q23.2 0 0 0 0 25 19 554 0.5231 0 0.378787878787879 Class A/1 (Rhodopsin-like receptors)(R)(0.9982446)-Gap junction(K)(0.9986216)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9987922)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9955534)-Neuroactive ligand-receptor interaction(K)(0.9976422)-Receptor-ligand complexes bind G proteins(R)(0.9959502)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9926186) 78 NEDD4 15q21.3 0 0 0 2 33 19 385 0.5231 0 0.53030303030303 Endocytosis(K)(0.99858)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9968604)-Ubiquitin mediated proteolysis(K)(0.9995484) 79 NUP98 11p15.4 0 0 0 3 29 19 512 0.5231 1 0.484848484848485 HIV Life Cycle(R)(0.9934294)-Host Interactions of HIV factors(R)(0.999104)-Influenza Life Cycle(R)(0.9967302)-M Phase(R)(0.9969506)-Metabolism of carbohydrates(R)(0.9988142)-Metabolism of non-coding RNA(R)(0.9942532)-Transport of Mature Transcript to Cytoplasm(R)(0.9946464) 80 OR1A1 17p13.3 0 0 0 1 36 19 413 0.5231 0 0.560606060606061 Olfactory Signaling Pathway(R)(0.9965252)-Olfactory transduction(K)(0.999168) 81 CACNA2D3 3p21.1 0 0 0 0 33 18 435 0.533 0 0.5 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.997629)-Cardiac muscle contraction(K)(0.998344)-Dilated cardiomyopathy(K)(0.9984106)-Hypertrophic cardiomyopathy (HCM)(K)(0.9936146)-MAPK signaling pathway(K)(0.9987196)-Synaptic Transmission(R)(0.9970256) 82 ITK 5q33.3 1 0 0 1 31 18 830 0.533 1 0.5 Chemokine signaling pathway(K)(0.9987896)-Fc-epsilon receptor I signaling in mast cells(N)(0.9964916)-Glypican pathway(N)(0.9992376)-Leukocyte transendothelial migration(K)(0.9990792)-T cell receptor signaling pathway(K)(0.9959856)-TCR signaling in naive CD4+ T cells(N)(0.9944692)-TCR signaling(R)(0.9951526)-TRAIL signaling pathway(N)(0.997663) 83 C5 9q33.2 0 0 0 0 19 16 505 0.5515 0 0.287878787878788 Class A/1 (Rhodopsin-like receptors)(R)(0.9992752)-Complement and coagulation cascades(K)(0.9976214)-Innate Immunity Signaling(R)(0.9967934)-Prion diseases(K)(0.9975788)-Receptor-ligand complexes bind G proteins(R)(0.9957832)-Systemic lupus erythematosus(K)(0.9985244) 84 MAPK3 16p11.2 0 0 0 0 12 16 2795 0.5515 0 0.181818181818182 Adherens junction(K)(0.9982394)-Aldosterone-regulated sodium reabsorption(K)(0.9930218)-Alzheimer disease-amyloid secretase pathway(P)(0.9804864)-Alzheimer's disease(K)(0.997828)-Axon guidance(K)(0.9976594)-BMP receptor signaling(N)(0.9664436)-Chemokine signaling pathway(K)(0.996425)-Dorso-ventral axis formation(K)(0.991366)-EGFR1(C)(0.9915408)-ErbB signaling pathway(K)(0.8693218)-Fc gamma R-mediated phagocytosis(K)(0.970334)-Focal adhesion(K)(0.8373534)-Gap junction(K)(0.9969722)-IL1-mediated signaling events(N)(0.9010576)-Insulin signaling pathway(K)(0.994657)-Integrin signalling pathway(P)(0.9937792)-MAPK signaling pathway(K)(0.9980824)-NOD-like receptor signaling pathway(K)(0.9863248)-NOTCH(C)(0.996035)-Natural killer cell mediated cytotoxicity(K)(0.9903632)-Neurotrophin signaling pathway(K)(0.9369518)-Oocyte meiosis(K)(0.9932278)-Parkinson disease(P)(0.997223)-Pathways in cancer(K)(0.97111)-Prion diseases(K)(0.9162484)-Progesterone-mediated oocyte maturation(K)(0.973777)-Proteogylcan syndecan-mediated signaling events(N)(0.995088)-Regulation of Telomerase(N)(0.997019)-Regulation of actin cytoskeleton(K)(0.9980918)-Retinoic acid receptors-mediated signaling(N)(0.9875444)-Signaling events mediated by PRL(N)(0.98667)-Signaling events regulated by Ret tyrosine kinase(N)(0.986843)-Signalling by NGF(R)(0.993831)-TGF-beta signaling pathway(K)(0.996367)-TNF receptor signaling pathway(N)(0.9645348)-Toll-like receptor signaling pathway(K)(0.9917644)-Transcription(R)(0.997158)-Vascular smooth muscle contraction(K)(0.9880564)-actions of nitric oxide in the heart(B)(0.9845306)-atm signaling pathway(B)(0.957564)-bone remodeling(B)(0.9084192)-cell cycle: g2/m checkpoint(B)(0.807936)-ion channels and their functional role in vascular endothelium(B)(0.98863)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9904646)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9823162)-nfat and hypertrophy of the heart (B)(0.9742672)-p75(NTR)-mediated signaling(N)(0.9689986)-role of nicotinic acetylcholine receptors in the regulation of apoptosis(B)(0.9671648) 85 CCNB1 5q13.2 0 0 0 3 31 16 524 0.5515 0 0.515151515151515 Cell Cycle Checkpoints(R)(0.9978654)-Cell cycle(K)(0.9979002)-FOXM1 transcription factor network(N)(0.9974562)-FoxO family signaling(N)(0.9984374)-G1/S Transition(R)(0.9963642)-G2/M Transition(R)(0.9993268)-Hedgehog(C)(0.9901038)-Oocyte meiosis(K)(0.9986834)-Progesterone-mediated oocyte maturation(K)(0.9989778)-akap95 role in mitosis and chromosome dynamics(B)(0.992754)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.9886758)-how progesterone initiates the oocyte maturation(B)(0.9947916)-il-2 receptor beta chain in t cell activation(B)(0.997592)-p53 signaling pathway(K)(0.9985638)-regulation of cell cycle progression by plk3(B)(0.8984278)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9934574) 86 MTFMT 15q22.31 0 0 0 1 27 16 58 0.5515 0 0.424242424242424 Aminoacyl-tRNA biosynthesis(K)(0.997939)-One carbon pool by folate(K)(0.9984824) 87 PKM2 15q23 0 0 0 0 23 16 1384 0.5515 0 0.348484848484849 Glucose Regulation of Insulin Secretion(R)(0.9988066)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9972076)-Metabolic pathways(K)(0.99831)-Metabolism of carbohydrates(R)(0.99834)-Purine metabolism(K)(0.9968528)-Pyruvate metabolism(K)(0.9959782)-Type II diabetes mellitus(K)(0.9980816) 88 CYP8B1 3p22.1 0 0 0 0 32 15 1241 0.5601 0 0.484848484848485 Biological oxidations(R)(0.996947)-Metabolic pathways(K)(0.9995264)-Metabolism of lipids and lipoproteins(R)(0.9981532)-PPAR signaling pathway(K)(0.9977858)-Primary bile acid biosynthesis(K)(0.9185872) 89 DIS3 13q22.1 0 0 0 2 29 15 59 0.5601 0 0.46969696969697 RNA degradation(K)(0.998933) 90 NDE1 16p13.11 1 1 0 1 21 15 171 0.5601 0 0.363636363636364 G2/M Transition(R)(0.9986096)-M Phase(R)(0.9974302) 91 DNM1 9q34.11 1 0 0 0 22 14 692 0.5786 0 0.348484848484849 Bacterial invasion of epithelial cells(K)(0.9970052)-EGFR1(C)(0.9985574)-Endocytosis(K)(0.9996326)-EphrinB-EPHB pathway(N)(0.993678)-Fc gamma R-mediated phagocytosis(K)(0.997629)-Gap junction trafficking and regulation(R)(0.9939066)-Signalling by NGF(R)(0.9988866)-Thromboxane A2 receptor signaling(N)(0.9966308)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9918954)-p75(NTR)-mediated signaling(N)(0.9970072)-ß-arrestins in gpcr desensitization(B)(0.9481392) 92 SNW1 14q24.3 0 0 0 0 34 14 366 0.5786 0 0.515151515151515 Generic Transcription Pathway(R)(0.9972284)-NOTCH(C)(0.9988004)-Notch signaling pathway(K)(0.997546)-Spliceosome(K)(0.9979946)-TGFBR(C)(0.998679)-control of gene expression by vitamin d receptor(B)(0.9915942) 93 SPCS3 4q34.2 0 0 0 2 28 13 61 0.5925 0 0.454545454545455 Insulin Synthesis and Secretion(R)(0.9974086)-Protein export(K)(0.9985534)-Vasopressin synthesis(P)(0.996051) 94 MAPK8 10q11.22 0 0 0 1 14 13 2330 0.5925 0 0.227272727272727 Adipocytokine signaling pathway(K)(0.9911776)-Alzheimer disease-amyloid secretase pathway(P)(0.9946506)-Angiogenesis(P)(0.9569358)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9362826)-Apoptosis signaling pathway(P)(0.984292)-Apoptosis(R)(0.9967938)-BMP receptor signaling(N)(0.978436)-EGFR1(C)(0.996608)-EphrinB-EPHB pathway(N)(0.9318754)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9694778)-FAS signaling pathway (CD95)(N)(0.9306104)-FAS signaling pathway(P)(0.95407)-Fc-epsilon receptor I signaling in mast cells(N)(0.9683676)-Focal adhesion(K)(0.9938964)-FoxO family signaling(N)(0.9886752)-Glypican pathway(N)(0.9599834)-GnRH signaling pathway(K)(0.850881)-IL1-mediated signaling events(N)(0.9917834)-IL12-mediated signaling events(N)(0.9979754)-IL2-mediated signaling events(N)(0.8343138)-Insulin signaling pathway(K)(0.996176)-Integrin signalling pathway(P)(0.9945854)-Integrins in angiogenesis(N)(0.972588)-MAPK signaling pathway(K)(0.9985012)-NOD-like receptor signaling pathway(K)(0.9887684)-Neurotrophin signaling pathway(K)(0.8315034)-Oxidative stress response(P)(0.963374)-Pathways in cancer(K)(0.9988122)-Progesterone-mediated oocyte maturation(K)(0.9881736)-Protein processing in endoplasmic reticulum(K)(0.998587)-Proteogylcan syndecan-mediated signaling events(N)(0.998126)-RIG-I-like receptor signaling pathway(K)(0.9877184)-Reelin signaling pathway(N)(0.9909632)-Retinoic acid receptors-mediated signaling(N)(0.9940626)-Shigellosis(K)(0.9938872)-Signaling events regulated by Ret tyrosine kinase(N)(0.972065)-Signalling by NGF(R)(0.9952198)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9763058)-TCR signaling in naive CD4+ T cells(N)(0.9867182)-TGF-beta signaling pathway(P)(0.9958206)-TGFBR(C)(0.9975206)-Toll-like receptor signaling pathway(K)(0.9963436)-Wnt signaling pathway(K)(0.9943918)-Wnt(C)(0.995739)-agrin in postsynaptic differentiation(B)(0.9952094)-how progesterone initiates the oocyte maturation(B)(0.8818566)-il-10 anti-inflammatory signaling pathway(B)(0.9051684)-lectin induced complement pathway(B)(0.8923938)-p75(NTR)-mediated signaling(N)(0.9874934) 95 PSAPL1 4p16.1 0 0 0 1 42 13 121 0.5925 0 0.651515151515151 Lysosome(K)(0.9986344) 96 CYP1A2 15q24.1 0 0 0 1 25 12 1176 0.5938 0 0.393939393939394 Drug metabolism - cytochrome P450(K)(0.9974484)-Metabolic pathways(K)(0.9989294)-Metabolism of xenobiotics by cytochrome P450(K)(0.998485) 97 PSMB6 17p13.2 0 0 0 1 33 12 392 0.5938 0 0.515151515151515 Apoptosis(R)(0.9979676)-Cell Cycle Checkpoints(R)(0.9976108)-Host Interactions of HIV factors(R)(0.9973294)-Metabolism of amino acids(R)(0.9978622)-Proteasome(K)(0.99313)-S Phase(R)(0.9980046)-Signaling by Wnt(R)(0.9960384) 98 POLE2 14q22.1 0 0 0 0 26 12 1391 0.5938 0 0.393939393939394 Base excision repair(K)(0.9960338)-DNA Repair(R)(0.9980536)-DNA replication(K)(0.9921092)-G1/S Transition(R)(0.8807902)-Metabolic pathways(K)(0.9988844)-Nucleotide excision repair(K)(0.9937124)-Purine metabolism(K)(0.997298)-Pyrimidine metabolism(K)(0.9907102)-S Phase(R)(0.9977308)-Telomere Maintenance(R)(0.996599) 99 ATP1B2 17p13.1 0 0 0 1 32 12 374 0.5938 0 0.5 Aldosterone-regulated sodium reabsorption(K)(0.9983326)-Cardiac muscle contraction(K)(0.9994312)-Cell surface interactions at the vascular wall(R)(0.9976624)-Gastric acid secretion(K)(0.9980024)-Pancreatic secretion(K)(0.9983182)-Proximal tubule bicarbonate reclamation(K)(0.9980398)-Salivary secretion(K)(0.9965058) 100 RAN 12q24.33 0 0 0 0 22 12 1216 0.5938 0 0.333333333333333 FoxO family signaling(N)(0.992087)-Glypican pathway(N)(0.9022164)-HIV Life Cycle(R)(0.994188)-Host Interactions of HIV factors(R)(0.9977862)-IL1-mediated signaling events(N)(0.9947846)-IL12-mediated signaling events(N)(0.993071)-IL2-mediated signaling events(N)(0.9778788)-IL23-mediated signaling events(N)(0.9860976)-Influenza Life Cycle(R)(0.998104)-LPA receptor mediated events(N)(0.9925776)-Regulatory RNA pathways(R)(0.831986)-Signaling by Aurora kinases(N)(0.9846094)-Signaling events mediated by HDAC Class I(N)(0.9982312)-Signaling events regulated by Ret tyrosine kinase(N)(0.988559)-TCR signaling in naive CD4+ T cells(N)(0.9923194)-TNF receptor signaling pathway(N)(0.9889548)-TRAIL signaling pathway(N)(0.9804508)-mechanism of protein import into the nucleus(B)(0.960763)-p75(NTR)-mediated signaling(N)(0.997457) 101 ADRA1D 20p13 0 0 1 1 11 12 662 0.5938 0 0.196969696969697 Calcium signaling pathway(K)(0.998599)-Class A/1 (Rhodopsin-like receptors)(R)(0.9034)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9985906)-Neuroactive ligand-receptor interaction(K)(0.9987694)-Salivary secretion(K)(0.9957502)-Vascular smooth muscle contraction(K)(0.9969768) 102 GLUD1 10q23.2 0 0 0 1 16 11 1211 0.6057 0 0.257575757575758 Alanine, aspartate and glutamate metabolism(K)(0.9967696)-Metabolic pathways(K)(0.9990842)-Metabolism of amino acids(R)(0.9980318)-Nitrogen metabolism(K)(0.994954)-Proximal tubule bicarbonate reclamation(K)(0.9972188) 103 CCNB2 15q22.2 0 0 0 2 26 11 499 0.6057 0 0.424242424242424 Cell Cycle Checkpoints(R)(0.9975904)-Cell cycle(K)(0.9964412)-FOXM1 transcription factor network(N)(0.994935)-G2/M Transition(R)(0.9988248)-Oocyte meiosis(K)(0.9988558)-Progesterone-mediated oocyte maturation(K)(0.9932214)-TGFBR(C)(0.998684)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.9889352)-p53 signaling pathway(K)(0.9972766) 104 OR4K14 14q11.2 0 0 0 0 21 11 413 0.6057 0 0.318181818181818 Olfactory Signaling Pathway(R)(0.998084)-Olfactory transduction(K)(0.9987798) 105 PARK2 6q26 0 0 0 2 23 11 468 0.6057 0 0.378787878787879 Alpha-synuclein signaling(N)(0.9898934)-Parkinson disease(P)(0.9985678)-Parkinson's disease(K)(0.9976696)-Protein processing in endoplasmic reticulum(K)(0.9979892)-Ubiquitin mediated proteolysis(K)(0.9989918) 106 YWHAE 17p13.3 0 0 0 1 37 11 1333 0.6057 0 0.575757575757576 BMP receptor signaling(N)(0.994851)-Cell cycle(K)(0.9987324)-EGF receptor signaling pathway(P)(0.9883822)-Endothelins(N)(0.9800818)-FGF signaling pathway(P)(0.9963544)-FoxO family signaling(N)(0.9896128)-G2/M Transition(R)(0.9986816)-Glypican pathway(N)(0.9970404)-IFN-gamma pathway(N)(0.9944)-IL1-mediated signaling events(N)(0.9908014)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9931882)-Neurotrophin signaling pathway(K)(0.9879188)-Oocyte meiosis(K)(0.9949272)-Parkinson disease(P)(0.9983528)-Plasma membrane estrogen receptor signaling(N)(0.9961062)-Proteogylcan syndecan-mediated signaling events(N)(0.9964842)-Regulation of Telomerase(N)(0.9969118)-Signaling events mediated by HDAC Class I(N)(0.996946)-Signalling by NGF(R)(0.9991616)-TNF receptor signaling pathway(N)(0.9916776)-TRAIL signaling pathway(N)(0.9824774)-a6b1 and a6b4 Integrin signaling(N)(0.9925726)-p75(NTR)-mediated signaling(N)(0.996637) 107 F7 13q34 0 0 1 0 26 10 272 0.6228 0 0.409090909090909 Complement and coagulation cascades(K)(0.998466)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.9963018)-Metabolism of proteins(R)(0.9971706) 108 GLA 23q22.1 0 0 0 4 24 10 231 0.6228 0 0.424242424242424 Galactose metabolism(K)(0.9989086)-Glycerolipid metabolism(K)(0.9981012)-Glycosphingolipid biosynthesis - globo series(K)(0.989658)-Lysosome(K)(0.9979928)-Sphingolipid metabolism(K)(0.9987184) 109 CYB5R3 22q13.2 0 0 0 0 20 10 57 0.6228 0 0.303030303030303 Amino sugar and nucleotide sugar metabolism(K)(0.9979806)-Metabolism of vitamins and cofactors(R)(0.9955894) 110 ABCD4 14q24.3 0 0 0 0 32 10 118 0.6228 0 0.484848484848485 ABC transporters(K)(0.9961622)-Peroxisome(K)(0.998426) 111 NDUFA1 23q24 0 0 0 6 24 10 1332 0.6228 0 0.454545454545455 Alzheimer's disease(K)(0.99802)-Glucose Regulation of Insulin Secretion(R)(0.9953124)-Huntington's disease(K)(0.9986352)-Metabolic pathways(K)(0.9979836)-Oxidative phosphorylation(K)(0.9984444)-Parkinson's disease(K)(0.9972086) 112 IKBKG 23q28 0 0 1 2 27 9 1642 0.6307 0 0.454545454545455 Acute myeloid leukemia(K)(0.959538)-Adipocytokine signaling pathway(K)(0.9973184)-Apoptosis(K)(0.9971734)-B cell receptor signaling pathway(K)(0.9844806)-Chagas disease(K)(0.9950474)-Chemokine signaling pathway(K)(0.9984852)-Cytosolic DNA-sensing pathway(K)(0.9964346)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9979938)-Fc-epsilon receptor I signaling in mast cells(N)(0.9802898)-Glypican pathway(N)(0.8163898)-IL12-mediated signaling events(N)(0.9965038)-IL2-mediated signaling events(N)(0.9923604)-IL23-mediated signaling events(N)(0.9788212)-LPA receptor mediated events(N)(0.9906)-MAPK signaling pathway(K)(0.9976226)-NOD-like receptor signaling pathway(K)(0.9921546)-Pathways in cancer(K)(0.9973802)-Primary immunodeficiency(K)(0.9937818)-Prostate cancer(K)(0.9896194)-RIG-I-like receptor signaling pathway(K)(0.9965382)-Shigellosis(K)(0.9968784)-Signaling by Aurora kinases(N)(0.9599414)-Signaling events regulated by Ret tyrosine kinase(N)(0.9940152)-T cell receptor signaling pathway(K)(0.9863134)-TCR signaling in naive CD4+ T cells(N)(0.9929396)-TCR signaling(R)(0.9892686)-TNF alpha/NF-kB(C)(0.9983898)-TNF receptor signaling pathway(N)(0.9984786)-Toll-like receptor signaling pathway(K)(0.9126678)-double stranded rna induced gene expression(B)(0.9796702)-lectin induced complement pathway(B)(0.9524856)-p75(NTR)-mediated signaling(N)(0.9985984)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9940768) 113 ITGA1 5q11.2 0 0 0 4 31 9 720 0.6307 0 0.53030303030303 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.995816)-Dilated cardiomyopathy(K)(0.9968702)-ECM-receptor interaction(K)(0.994328)-Focal adhesion(K)(0.9983768)-Hematopoietic cell lineage(K)(0.9994746)-Hypertrophic cardiomyopathy (HCM)(K)(0.9869412)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.996127)-Integrin cell surface interactions(R)(0.9982746)-Integrin signalling pathway(P)(0.9983852)-Regulation of actin cytoskeleton(K)(0.9986892)-Signaling events mediated by PRL(N)(0.9896954)-VEGFR3 signaling in lymphatic endothelium(N)(0.9797766)-agrin in postsynaptic differentiation(B)(0.9958396)-b cell survival pathway(B)(0.9912024)-mcalpain and friends in cell motility(B)(0.972514) 114 EGFR 7p11.2 1 4 0 0 6 9 1700 0.6307 1 0.166666666666667 Alpha6Beta4Integrin(C)(0.9426644)-Calcium signaling pathway(K)(0.998487)-Cytokine-cytokine receptor interaction(K)(0.9986066)-Dorso-ventral axis formation(K)(0.9766138)-EGF receptor signaling pathway(P)(0.9934708)-EGFR1(C)(0.9947136)-Endocytosis(K)(0.9986468)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9960022)-Focal adhesion(K)(0.9899816)-Gap junction(K)(0.9953404)-MAPK signaling pathway(K)(0.9994468)-Pathways in cancer(K)(0.9995582)-Prostate cancer(K)(0.9930252)-Proteogylcan syndecan-mediated signaling events(N)(0.9975694)-Regulation of Telomerase(N)(0.9975818)-Regulation of actin cytoskeleton(K)(0.9962728)-Thromboxane A2 receptor signaling(N)(0.9922688) 115 GZMB 14q12 0 0 0 0 25 9 663 0.6307 0 0.378787878787879 Apoptosis(R)(0.99729)-Autoimmune thyroid disease(K)(0.9934464)-IL12-mediated signaling events(N)(0.9955094)-Natural killer cell mediated cytotoxicity(K)(0.9994572)-TCR signaling in naive CD8+ T cells(N)(0.9963602)-TNF receptor signaling pathway(N)(0.9983078)-TRAIL signaling pathway(N)(0.9911522)-Type I diabetes mellitus(K)(0.9960206)-granzyme a mediated apoptosis pathway(B)(0.9855022) 116 SEPSECS 4p15.2 0 0 1 1 34 9 41 0.6307 0 0.545454545454545 Aminoacyl-tRNA biosynthesis(K)(0.998675) 117 PGM2 4p14 1 0 0 1 30 9 1203 0.6307 0 0.484848484848485 Amino sugar and nucleotide sugar metabolism(K)(0.9965064)-Metabolic pathways(K)(0.9991476)-Pentose phosphate pathway(K)(0.965097)-Purine metabolism(K)(0.9986156)-Starch and sucrose metabolism(K)(0.9967426) 118 RBM25 14q24.2 1 0 0 0 34 9 128 0.6307 0 0.53030303030303 Spliceosome(K)(0.999046) 119 ENO3 17p13.2 0 0 0 1 35 9 1275 0.6307 0 0.545454545454545 Glucose Regulation of Insulin Secretion(R)(0.9989848)-Metabolic pathways(K)(0.999369)-Metabolism of carbohydrates(R)(0.9993556)-RNA degradation(K)(0.9969834) 120 POLD1 19q13.33 0 0 0 0 13 8 1407 0.6436 0 0.196969696969697 Base excision repair(K)(0.9977118)-DNA Repair(R)(0.997077)-DNA replication(K)(0.996633)-G1/S Transition(R)(0.9417244)-Homologous recombination(K)(0.9961062)-Metabolic pathways(K)(0.9978396)-Mismatch repair(K)(0.986475)-Nucleotide excision repair(K)(0.9961502)-Purine metabolism(K)(0.9980906)-Pyrimidine metabolism(K)(0.9116362)-Telomere Maintenance(R)(0.9966146) 121 CHST7 23p11.3 0 0 1 6 22 8 22 0.6436 0 0.439393939393939 Glycosaminoglycan biosynthesis - chondroitin sulfate(K)(0.9990666) 122 GOT2 16q21 1 0 0 1 18 8 1252 0.6436 0 0.287878787878788 Alanine, aspartate and glutamate metabolism(K)(0.9820704)-Metabolic pathways(K)(0.9988584)-Metabolism of amino acids(R)(0.9977738)-Metabolism of carbohydrates(R)(0.999107)-Tyrosine metabolism(K)(0.8189184) 123 ALDH3A1 17p11.2 0 0 1 1 37 8 1169 0.6436 0 0.590909090909091 Drug metabolism - cytochrome P450(K)(0.9983294)-Histidine metabolism(K)(0.9832988)-Metabolic pathways(K)(0.9994506)-Metabolism of xenobiotics by cytochrome P450(K)(0.9979096) 124 FUT8 14q23.3 0 0 0 0 36 8 1128 0.6436 0 0.545454545454545 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.997935)-Metabolic pathways(K)(0.9982266)-N-Glycan biosynthesis(K)(0.996147) 125 SEC61G 7p11.2 0 3 0 0 5 8 377 0.6436 0 0.121212121212121 Insulin Synthesis and Secretion(R)(0.9974952)-Phagosome(K)(0.9968426)-Protein processing in endoplasmic reticulum(K)(0.9994872)-Vibrio cholerae infection(K)(0.9907098) 126 ATG4B 2q37.3 0 0 0 1 22 8 35 0.6436 0 0.348484848484849 Regulation of autophagy(K)(0.9991278) 127 JUN 1p32.1 1 0 0 0 8 7 2127 0.6436 1 0.136363636363636 AndrogenReceptor(C)(0.9967958)-Angiogenesis(P)(0.986934)-Apoptosis signaling pathway(P)(0.9877866)-B cell receptor signaling pathway(K)(0.8658572)-EGFR1(C)(0.998763)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9938496)-FOXA transcription factor networks(N)(0.978419)-Fc-epsilon receptor I signaling in mast cells(N)(0.9654448)-Focal adhesion(K)(0.998243)-Glypican pathway(N)(0.995138)-GnRH signaling pathway(K)(0.8573578)-HIF-1-alpha transcription factor network(N)(0.8020832)-Huntington disease(P)(0.997721)-IL1-mediated signaling events(N)(0.9834836)-IL12-mediated signaling events(N)(0.9957786)-IL6-mediated signaling events(N)(0.975928)-Integrins in angiogenesis(N)(0.9582962)-MAPK signaling pathway(K)(0.9952168)-Neurotrophin signaling pathway(K)(0.9303664)-Oxidative stress response(P)(0.9801318)-Pathways in cancer(K)(0.9990334)-Proteogylcan syndecan-mediated signaling events(N)(0.998123)-Ras Pathway(P)(0.971395)-Regulation of retinoblastoma protein(N)(0.996103)-Signaling events regulated by Ret tyrosine kinase(N)(0.8287846)-TCR signaling in naive CD4+ T cells(N)(0.9892308)-TGF-beta signaling pathway(P)(0.9950742)-TNF receptor signaling pathway(N)(0.9913238)-Toll-like receptor signaling pathway(K)(0.9949232)-Wnt signaling pathway(K)(0.9988004)-agrin in postsynaptic differentiation(B)(0.9912092)-atm signaling pathway(B)(0.9122804)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9970098)-oxidative stress induced gene expression via nrf2(B)(0.9727804)-t cell receptor signaling pathway(B)(0.8350606)-the information processing pathway at the ifn beta enhancer(B)(0.8878812) 128 EDNRA 4q31.23 1 0 0 1 21 7 685 0.6436 0 0.348484848484849 Calcium signaling pathway(K)(0.9974994)-Class A/1 (Rhodopsin-like receptors)(R)(0.9987594)-Endothelin signaling pathway(P)(0.9953122)-Endothelins(N)(0.9972514)-Neuroactive ligand-receptor interaction(K)(0.9990992)-Vascular smooth muscle contraction(K)(0.9967884)-role of egf receptor transactivation by gpcrs in cardiac hypertrophy(B)(0.9922426) 129 ARNTL 11p15.2 0 0 0 1 23 7 30 0.6436 0 0.363636363636364 Circadian rhythm - mammal(K)(0.9983366)-Circadian rhythm pathway(N)(0.9982776) 130 ESR1 6q25.1 0 0 1 0 17 7 1003 0.6436 0 0.272727272727273 AndrogenReceptor(C)(0.9988754)-FOXA transcription factor networks(N)(0.983665)-FOXM1 transcription factor network(N)(0.9926724)-Glypican pathway(N)(0.9971406)-IFN-gamma pathway(N)(0.9970874)-IL1-mediated signaling events(N)(0.9968822)-Plasma membrane estrogen receptor signaling(N)(0.9951634)-Regulation of Telomerase(N)(0.9987214)-Signaling by BMP(R)(0.97195)-Signaling events mediated by HDAC Class I(N)(0.9978616)-TGFBR(C)(0.9982906)-TNF receptor signaling pathway(N)(0.997441)-downregulated of mta-3 in er-negative breast tumors(B)(0.9903086)-estrogen responsive protein efp controls cell cycle and breast tumors growth(B)(0.992828) 131 TUBA3C 13q12.11 0 0 0 0 28 7 474 0.6436 0 0.424242424242424 Gap junction(K)(0.9980656)-Metabolism of proteins(R)(0.998122)-Pathogenic Escherichia coli infection(K)(0.9974482)-Phagosome(K)(0.9993722)-downregulated of mta-3 in er-negative breast tumors(B)(0.9960656)-stathmin and breast cancer resistance to antimicrotubule agents(B)(0.9974092) 132 FOS 14q24.3 0 0 0 0 30 7 1881 0.6436 0 0.454545454545455 Androgen-mediated signaling(N)(0.9671216)-Angiogenesis(P)(0.974867)-B cell receptor signaling pathway(K)(0.9789108)-BMP receptor signaling(N)(0.9898198)-Chagas disease(K)(0.9941402)-EGFR1(C)(0.9942798)-Endothelins(N)(0.9423072)-FOXA transcription factor networks(N)(0.9352812)-FOXM1 transcription factor network(N)(0.9898134)-Fc-epsilon receptor I signaling in mast cells(N)(0.9884004)-Glypican pathway(N)(0.9943472)-Huntington disease(P)(0.998353)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9954664)-IL1-mediated signaling events(N)(0.989261)-IL12-mediated signaling events(N)(0.9955498)-IL2-mediated signaling events(N)(0.9435404)-IL6-mediated signaling events(N)(0.9878866)-Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade(P)(0.8324452)-Integrins in angiogenesis(N)(0.9949282)-Interleukin signaling pathway(P)(0.9441864)-LPA receptor mediated events(N)(0.992512)-Leishmaniasis(K)(0.9907668)-MAPK signaling pathway(K)(0.997704)-Pathways in cancer(K)(0.9980568)-Plasma membrane estrogen receptor signaling(N)(0.9471184)-Proteogylcan syndecan-mediated signaling events(N)(0.9439278)-Regulation of Telomerase(N)(0.995185)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9691196)-T cell receptor signaling pathway(K)(0.9948078)-TCR signaling in naive CD4+ T cells(N)(0.9920256)-TGF-beta signaling pathway(P)(0.9966892)-TGFBR(C)(0.9978714)-TNF receptor signaling pathway(N)(0.9691678)-TRAIL signaling pathway(N)(0.9860704)-Toll-like receptor signaling pathway(K)(0.994882)-bone remodeling(B)(0.9585428)-il-2 receptor beta chain in t cell activation(B)(0.835495)-mets affect on macrophage differentiation(B)(0.9899998)-oxidative stress induced gene expression via nrf2(B)(0.9884286)-p75(NTR)-mediated signaling(N)(0.9957782)-repression of pain sensation by the transcriptional regulator dream(B)(0.9121726)-t cell receptor signaling pathway(B)(0.980818)-toll-like receptor pathway(B)(0.9515636) 133 EP300 22q13.2 0 0 0 0 17 7 2220 0.6436 1 0.257575757575758 Adherens junction(K)(0.9953292)-Androgen-mediated signaling(N)(0.9635112)-AndrogenReceptor(C)(0.9838046)-BMP receptor signaling(N)(0.980662)-Cell cycle(K)(0.9939568)-Endothelins(N)(0.9657612)-FOXA transcription factor networks(N)(0.9717964)-FOXM1 transcription factor network(N)(0.9888954)-FoxO family signaling(N)(0.9756268)-Glypican pathway(N)(0.9964654)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9987496)-Huntington disease(P)(0.9988968)-Huntington's disease(K)(0.9954756)-Hypoxia response via HIF activation(P)(0.8980624)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9945118)-IL1-mediated signaling events(N)(0.9909132)-Jak-STAT signaling pathway(K)(0.9987772)-Long-term potentiation(K)(0.9866394)-NOTCH(C)(0.9926214)-Notch signaling pathway(K)(0.9959114)-Pathways in cancer(K)(0.997817)-Plasma membrane estrogen receptor signaling(N)(0.981724)-Regulation of retinoblastoma protein(N)(0.9932364)-Renal cell carcinoma(K)(0.9825022)-Retinoic acid receptors-mediated signaling(N)(0.9621486)-Signaling events mediated by HDAC Class I(N)(0.9965092)-TGF-beta signaling pathway(K)(0.9908334)-TGFBR(C)(0.9954454)-TNF receptor signaling pathway(N)(0.9913954)-TRAIL signaling pathway(N)(0.9877602)-Wnt signaling pathway(K)(0.9778104)-Wnt signaling pathway(P)(0.9993712)-Wnt(C)(0.9942434)-granzyme a mediated apoptosis pathway(B)(0.9744654)-hypoxia-inducible factor in the cardivascular system(B)(0.919718)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9885812)-nfat and hypertrophy of the heart (B)(0.9919958)-regulation of transcriptional activity by pml(B)(0.9562786)-role of erbb2 in signal transduction and oncology(B)(0.9255034)-the information processing pathway at the ifn beta enhancer(B)(0.988635) 134 BDKRB2 14q32.2 0 0 0 0 30 7 906 0.6436 0 0.454545454545455 Calcium signaling pathway(K)(0.9988284)-Chagas disease(K)(0.996758)-Class A/1 (Rhodopsin-like receptors)(R)(0.9983408)-Complement and coagulation cascades(K)(0.997431)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.997916)-Neuroactive ligand-receptor interaction(K)(0.9992204)-Receptor-ligand complexes bind G proteins(R)(0.992005)-Regulation of actin cytoskeleton(K)(0.998475)-actions of nitric oxide in the heart(B)(0.9921134)-ion channels and their functional role in vascular endothelium(B)(0.9966836)-vegf hypoxia and angiogenesis(B)(0.993785) 135 CUL4A 13q34 0 0 1 0 26 7 176 0.6436 0 0.409090909090909 Nucleotide excision repair(K)(0.9977054)-Ubiquitin mediated proteolysis(K)(0.9982746) 136 MYO5A 15q21.2 2 0 0 1 31 7 94 0.6436 0 0.515151515151515 Insulin Synthesis and Secretion(R)(0.9988888)-Nicotinic acetylcholine receptor signaling pathway(P)(0.9973134) 137 ENPP1 6q23.2 0 0 1 0 5 6 1216 0.6436 0 0.0909090909090909 Metabolic pathways(K)(0.9985842)-Purine metabolism(K)(0.9983828) 138 GTF2E2 8p12 0 0 0 2 29 6 254 0.6436 0 0.46969696969697 Basal transcription factors(K)(0.9911076)-Formation and Maturation of mRNA Transcript(R)(0.9982398)-HIV Life Cycle(R)(0.9970376)-Transcription(R)(0.9987186) 139 FGFR3 4p16.3 0 0 0 1 32 6 975 0.6436 1 0.5 Endocytosis(K)(0.9992312)-FGF signaling pathway(P)(0.9965812)-MAPK signaling pathway(K)(0.9988462)-Pathways in cancer(K)(0.9980298)-Proteogylcan syndecan-mediated signaling events(N)(0.9973586)-Regulation of actin cytoskeleton(K)(0.9963146) 140 DYNC1H1 14q32.31 1 0 0 0 26 6 399 0.6436 0 0.409090909090909 G2/M Transition(R)(0.9988554)-Huntington disease(P)(0.9981132)-Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9927632)-Phagosome(K)(0.997344)-Vasopressin-regulated water reabsorption(K)(0.9960706) 141 LAP3 4p15.32 0 0 0 1 37 6 1151 0.6436 0 0.575757575757576 Glutathione metabolism(K)(0.9977)-Metabolic pathways(K)(0.9979762) 142 B3GAT1 11q25 0 0 0 3 28 6 1139 0.6436 0 0.46969696969697 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9989218)-Metabolic pathways(K)(0.9993622) 143 LAMB2 3p21.31 1 0 0 0 31 6 665 0.6436 0 0.484848484848485 Amoebiasis(K)(0.998173)-ECM-receptor interaction(K)(0.9967882)-Focal adhesion(K)(0.9981028)-Integrin cell surface interactions(R)(0.9969976)-Integrin signalling pathway(P)(0.998687)-Pathways in cancer(K)(0.9986542)-a6b1 and a6b4 Integrin signaling(N)(0.9963988)-agrin in postsynaptic differentiation(B)(0.9967992)-prion pathway(B)(0.9964984) 144 HMOX2 16p13.3 0 0 0 1 22 6 58 0.6436 0 0.348484848484849 Porphyrin and chlorophyll metabolism(K)(0.999539)-oxidative stress induced gene expression via nrf2(B)(0.99813) 145 B2M 15q21.1 1 0 0 2 32 6 480 0.6436 0 0.53030303030303 Antigen processing and presentation(K)(0.9985396)-Host Interactions of HIV factors(R)(0.9979402)-IL12-mediated signaling events(N)(0.9983136)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9966148)-T cell activation(P)(0.9975072)-TCR signaling in naive CD8+ T cells(N)(0.9978398)-ras-independent pathway in nk cell-mediated cytotoxicity(B)(0.9931876) 146 LPL 8p21.3 1 0 0 1 26 6 385 0.6436 0 0.424242424242424 Alzheimer's disease(K)(0.9985592)-Glycerolipid metabolism(K)(0.9953234)-Metabolism of lipids and lipoproteins(R)(0.99893)-PPAR signaling pathway(K)(0.9971232)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9976114) 147 ARAP2 4p14 0 0 0 1 32 6 390 0.6436 0 0.5 Endocytosis(K)(0.9990862)-Signaling by Rho GTPases(R)(0.998585)-adp-ribosylation factor(B)(0.9975526)-rac1 cell motility signaling pathway(B)(0.9953132)-rho cell motility signaling pathway(B)(0.9986034)-t cell receptor signaling pathway(B)(0.9977606) 148 DYNLL2 17q22 0 0 0 0 24 6 290 0.6436 0 0.363636363636364 Apoptosis(R)(0.9981932)-Huntington disease(P)(0.9981586)-Vasopressin-regulated water reabsorption(K)(0.997513) 149 NFATC1 18q23 0 0 0 0 25 5 1323 0.6436 0 0.378787878787879 Axon guidance(K)(0.9972522)-BMP receptor signaling(N)(0.9960788)-Endothelins(N)(0.9854742)-Glypican pathway(N)(0.9962342)-IFN-gamma pathway(N)(0.9949192)-IL1-mediated signaling events(N)(0.9970962)-Natural killer cell mediated cytotoxicity(K)(0.9943632)-Plasma membrane estrogen receptor signaling(N)(0.9684748)-T cell receptor signaling pathway(K)(0.9890956)-TCR signaling in naive CD4+ T cells(N)(0.9837956)-TNF receptor signaling pathway(N)(0.9971312)-TRAIL signaling pathway(N)(0.9527282)-VEGF signaling pathway(K)(0.988145)-Wnt signaling pathway(K)(0.9976958)-Wnt signaling pathway(P)(0.999262)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9636668)-gata3 participate in activating the th2 cytokine genes expression(B)(0.9053016)-nfat and hypertrophy of the heart (B)(0.9953724)-t cell receptor signaling pathway(B)(0.9803784) 150 PLG 6q26 0 0 0 0 16 5 854 0.6436 0 0.242424242424242 Complement and coagulation cascades(K)(0.9965514)-Formation of Platelet plug(R)(0.9980106)-Neuroactive ligand-receptor interaction(K)(0.9991668)-Proteogylcan syndecan-mediated signaling events(N)(0.9959458)-Regulation of IGF Activity by IGFBP(R)(0.993915)-Signaling by PDGF(R)(0.9966998)-amb2 Integrin signaling(N)(0.996727)-p75(NTR)-mediated signaling(N)(0.996764) 151 NUP214 9q34.13 0 0 0 0 23 5 1062 0.6436 1 0.348484848484849 BMP receptor signaling(N)(0.9939832)-Glypican pathway(N)(0.8731332)-HIV Life Cycle(R)(0.9971044)-Host Interactions of HIV factors(R)(0.9974572)-IFN-gamma pathway(N)(0.9989766)-Influenza Life Cycle(R)(0.999375)-Metabolism of carbohydrates(R)(0.9969308)-Metabolism of non-coding RNA(R)(0.9950936)-Signaling events mediated by HDAC Class I(N)(0.999193)-TGFBR(C)(0.996407)-Transport of Mature Transcript to Cytoplasm(R)(0.9936148)-mechanism of protein import into the nucleus(B)(0.9599746) 152 MAP2K4 17p12 0 0 0 1 35 5 1407 0.6436 1 0.545454545454545 BMP receptor signaling(N)(0.9978988)-Cellular roles of Anthrax toxin(N)(0.9876362)-Chagas disease(K)(0.9937796)-EphrinB-EPHB pathway(N)(0.9612942)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9990732)-ErbB signaling pathway(K)(0.995354)-FAS signaling pathway (CD95)(N)(0.967433)-FAS signaling pathway(P)(0.9924022)-Fc epsilon RI signaling pathway(K)(0.9767582)-Fc-epsilon receptor I signaling in mast cells(N)(0.9865622)-Glypican pathway(N)(0.9928256)-GnRH signaling pathway(K)(0.9980328)-IFN-gamma pathway(N)(0.8003556)-IL1-mediated signaling events(N)(0.9926632)-IL6-mediated signaling events(N)(0.994244)-Integrin signalling pathway(P)(0.9982462)-MAPK signaling pathway(K)(0.9989298)-Oxidative stress response(P)(0.9855)-Plasma membrane estrogen receptor signaling(N)(0.9899504)-Proteogylcan syndecan-mediated signaling events(N)(0.9989126)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9961212)-TCR signaling in naive CD4+ T cells(N)(0.9927868)-TNF receptor signaling pathway(N)(0.992634)-TRAIL signaling pathway(N)(0.9956774)-Toll-like receptor signaling pathway(K)(0.9969178)-VEGFR3 signaling in lymphatic endothelium(N)(0.9459604)-map kinase inactivation of smrt corepressor(B)(0.9921322)-p38 mapk signaling pathway(B)(0.9918684)-t cell receptor signaling pathway(B)(0.9861686)-toll-like receptor pathway(B)(0.9818142) 153 ICOS 2q33.2 0 0 0 0 15 5 279 0.6436 0 0.227272727272727 Cell adhesion molecules (CAMs)(K)(0.998169)-Intestinal immune network for IgA production(K)(0.9982564)-Primary immunodeficiency(K)(0.9976386)-T cell receptor signaling pathway(K)(0.9985342) 154 GJB1 23q13.1 0 0 0 6 25 5 20 0.6436 0 0.46969696969697 Gap junction trafficking and regulation(R)(0.998866) 155 CA5B 23p22.2 0 0 0 8 21 5 23 0.6436 0 0.439393939393939 Nitrogen metabolism(K)(0.9987808) 156 BNIP1 5q35.2 0 0 0 2 33 5 36 0.6436 0 0.53030303030303 SNARE interactions in vesicular transport(K)(0.9982798) 157 ACAT2 6q25.3 0 0 0 0 17 5 1173 0.6436 0 0.257575757575758 Butanoate metabolism(K)(0.8281872)-Fatty acid metabolism(K)(0.9951792)-Lysine degradation(K)(0.9995348)-Metabolic pathways(K)(0.998536)-Pyruvate metabolism(K)(0.9963098)-Terpenoid backbone biosynthesis(K)(0.9252366)-Tryptophan metabolism(K)(0.994539) 158 RDH12 14q24.1 0 0 0 0 33 5 1130 0.6436 0 0.5 Metabolic pathways(K)(0.9990716)-Retinol metabolism(K)(0.9968594) 159 WHSC1 4p16.3 1 0 0 1 32 5 44 0.6436 1 0.515151515151515 Lysine degradation(K)(0.9993706) 160 RB1 13q14.2 5 0 0 5 30 5 1060 0.6436 1 0.560606060606061 AndrogenReceptor(C)(0.9985552)-Cell cycle(K)(0.9972488)-DNA Replication(R)(0.9487496)-FAS signaling pathway (CD95)(N)(0.9912816)-FOXM1 transcription factor network(N)(0.993351)-G1/S Transition(R)(0.9854592)-Glioma(K)(0.9944686)-ID(C)(0.9970614)-Pathways in cancer(K)(0.9989414)-Prostate cancer(K)(0.9896998)-Regulation of retinoblastoma protein(N)(0.99683)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9973846)-TGFBR(C)(0.9979628)-TNF receptor signaling pathway(N)(0.9969708)-TRAIL signaling pathway(N)(0.9985994)-il-2 receptor beta chain in t cell activation(B)(0.9919066)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9973348)-regulation of transcriptional activity by pml(B)(0.9683662)-telomeres telomerase cellular aging and immortality(B)(0.9937878)-tumor suppressor arf inhibits ribosomal biogenesis(B)(0.9579734) 161 DMD 23p21.1 0 0 0 8 22 5 232 0.6436 0 0.454545454545455 Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.9980744)-Dilated cardiomyopathy(K)(0.9955496)-Hypertrophic cardiomyopathy (HCM)(K)(0.9927836)-Muscle contraction(R)(0.9934782)-Viral myocarditis(K)(0.9989786)-agrin in postsynaptic differentiation(B)(0.9978526) 162 GSTZ1 14q24.3 0 0 0 0 33 5 1173 0.6436 0 0.5 Drug metabolism - cytochrome P450(K)(0.984313)-Glutathione metabolism(K)(0.9977608)-Metabolic pathways(K)(0.998516)-Metabolism of xenobiotics by cytochrome P450(K)(0.9983824)-Tyrosine metabolism(K)(0.9946264) 163 MAN2C1 15q24.2 0 0 0 1 23 5 26 0.6436 0 0.363636363636364 Other glycan degradation(K)(0.998595)-er associated degradation (erad) pathway(B)(0.9980764) 164 WDR12 2q33.1 0 0 0 0 16 5 66 0.6436 0 0.242424242424242 NOTCH(C)(0.9991562) 165 PLK1 16p12.1 0 0 0 1 17 5 444 0.6436 0 0.272727272727273 Cell cycle(K)(0.9991284)-FOXM1 transcription factor network(N)(0.9963106)-FoxO family signaling(N)(0.9980558)-G2/M Transition(R)(0.997292)-M Phase(R)(0.9989836)-Oocyte meiosis(K)(0.9962824)-Progesterone-mediated oocyte maturation(K)(0.997722) 166 ABCC3 17q21.33 0 0 0 0 26 5 144 0.6436 0 0.393939393939394 ABC transporters(K)(0.9984018)-Metabolism of lipids and lipoproteins(R)(0.9976272) 167 EXOSC2 9q34.12 1 0 0 0 23 5 59 0.6436 0 0.363636363636364 RNA degradation(K)(0.9989376) 168 GSK3B 3q13.33 0 0 0 0 5 5 2291 0.6436 0 0.0757575757575758 APC/C-mediated degradation of cell cycle proteins(R)(0.989945)-Alzheimer disease-presenilin pathway(P)(0.9987848)-Alzheimer's disease(K)(0.995278)-Axon guidance(K)(0.9968136)-Cadherin signaling pathway(P)(0.9118202)-Chemokine signaling pathway(K)(0.9733158)-Coregulation of Androgen receptor activity(N)(0.8876288)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9933774)-NOTCH(C)(0.9643412)-Pathways in cancer(K)(0.9550084)-Signalling by NGF(R)(0.9610854) 169 PPAP2C 19p13.3 0 0 1 3 32 5 1228 0.6436 0 0.545454545454545 Ether lipid metabolism(K)(0.9708248)-Fc gamma R-mediated phagocytosis(K)(0.9987306)-Glycerophospholipid metabolism(K)(0.9978592)-Metabolic pathways(K)(0.9987692)-Sphingolipid metabolism(K)(0.9962442) 170 SLC25A6 23p22.33 0 0 0 9 34 5 599 0.6436 0 0.651515151515151 Calcium signaling pathway(K)(0.9984712)-Glucose Regulation of Insulin Secretion(R)(0.9985088)-Host Interactions of HIV factors(R)(0.9987862)-Huntington's disease(K)(0.9977506)-Metablism of nucleotides(R)(0.9988324)-Parkinson's disease(K)(0.9966798) 171 CNTNAP2 7q35 1 0 0 0 16 5 135 0.6436 0 0.257575757575758 Cell adhesion molecules (CAMs)(K)(0.9991422) 172 FMN2 1q43 3 0 2 0 0 4 25 0.6436 0 0.0757575757575758 Dorso-ventral axis formation(K)(0.9983214) 173 CCL11 17q12 0 0 2 0 34 4 828 0.6436 0 0.545454545454545 Asthma(K)(0.9964714)-Chemokine signaling pathway(K)(0.9984228)-Cytokine-cytokine receptor interaction(K)(0.9990468)-IFN-gamma pathway(N)(0.99916)-NOD-like receptor signaling pathway(K)(0.9984342)-ccr3 signaling in eosinophils(B)(0.9969068)-chrebp regulation by carbohydrates and camp(B)(0.9951374)-cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway(B)(0.9619744)-ion channels and their functional role in vascular endothelium(B)(0.9978308)-ß-arrestins in gpcr desensitization(B)(0.9910952) 174 CRMP1 4p16.1 0 0 0 1 39 4 10 0.6436 0 0.606060606060606 Axon guidance mediated by semaphorins(P)(0.999238) 175 IDI2 10p15.3 0 0 1 0 9 4 1123 0.6436 0 0.151515151515152 Metabolic pathways(K)(0.9992214)-Terpenoid backbone biosynthesis(K)(0.9805816) 176 FUT7 9q34.3 0 0 0 0 23 4 27 0.6436 0 0.348484848484849 Glycosphingolipid biosynthesis - lacto and neolacto series(K)(0.9985768) 177 ULK2 17p11.2 0 0 1 1 37 4 81 0.6436 0 0.590909090909091 Regulation of autophagy(K)(0.9984584)-mTOR signaling pathway(K)(0.9980362) 178 PLCE1 10q23.33 2 0 0 0 17 4 1392 0.6436 0 0.287878787878788 Calcium signaling pathway(K)(0.9985214)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9956632)-Metabolic pathways(K)(0.9990948) 179 MAGOHB 12p13.2 1 1 3 0 9 4 128 0.6436 0 0.212121212121212 Spliceosome(K)(0.998807) 180 SMAD5 5q31.2 0 0 0 3 32 4 332 0.6436 0 0.53030303030303 BMP receptor signaling(N)(0.998004)-Signaling by BMP(R)(0.9963662)-TGF-beta signaling pathway(K)(0.9982662)-TGF-beta signaling pathway(P)(0.9991682)-ctcf: first multivalent nuclear factor(B)(0.9948072) 181 MED17 11q21 0 0 0 0 16 4 33 0.6436 0 0.242424242424242 Generic Transcription Pathway(R)(0.9980624) 182 MYO1C 17p13.3 0 0 0 1 36 4 46 0.6436 0 0.560606060606061 Nicotinic acetylcholine receptor signaling pathway(P)(0.9991822) 183 EBP 23p11.23 0 0 0 7 23 4 1123 0.6436 0 0.454545454545455 Metabolic pathways(K)(0.997725)-Steroid biosynthesis(K)(0.9972078) 184 HSPH1 13q12.3 1 0 0 0 26 4 167 0.6436 0 0.409090909090909 Protein processing in endoplasmic reticulum(K)(0.9985196) 185 ATF6 1q23.3 0 0 6 0 1 4 1019 0.6436 0 0.106060606060606 Alzheimer's disease(K)(0.9942682)-BMP receptor signaling(N)(0.990995)-Glypican pathway(N)(0.9678834)-IFN-gamma pathway(N)(0.8183888)-Plasma membrane estrogen receptor signaling(N)(0.9982114)-Protein processing in endoplasmic reticulum(K)(0.9996494)-TNF receptor signaling pathway(N)(0.99756) 186 SNRPD1 18q11.2 0 0 0 0 13 4 502 0.6436 0 0.196969696969697 Formation and Maturation of mRNA Transcript(R)(0.9991022)-Influenza Life Cycle(R)(0.9977664)-Metabolism of non-coding RNA(R)(0.9966846)-Spliceosome(K)(0.9991178)-Systemic lupus erythematosus(K)(0.9991934) 187 BMP15 23p11.22 1 0 0 7 20 4 91 0.6436 0 0.424242424242424 TGF-beta signaling pathway(P)(0.9988418) 188 CNOT7 8p22 0 0 0 1 27 4 59 0.6436 0 0.424242424242424 RNA degradation(K)(0.9984698) 189 RPL18A 19p13.11 0 0 2 0 18 4 313 0.6436 0 0.303030303030303 Influenza Life Cycle(R)(0.99789)-Metabolism of proteins(R)(0.9987856)-Ribosome(K)(0.9665546) 190 ARHGEF3 3p14.3 0 0 0 0 37 4 125 0.6436 0 0.560606060606061 Signaling by Rho GTPases(R)(0.9990668) 191 MAPK11 22q13.33 0 0 0 0 19 3 1514 0.6436 0 0.287878787878788 Alzheimer disease-amyloid secretase pathway(P)(0.9959506)-Amyotrophic lateral sclerosis (ALS)(K)(0.994012)-BMP receptor signaling(N)(0.988562)-Chagas disease(K)(0.951762)-EGF receptor signaling pathway(P)(0.9866082)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9963338)-FGF signaling pathway(P)(0.8291654)-Glypican pathway(N)(0.9974102)-GnRH signaling pathway(K)(0.9786208)-IFN-gamma pathway(N)(0.8471258)-IL1-mediated signaling events(N)(0.982711)-IL2-mediated signaling events(N)(0.9898304)-IL6-mediated signaling events(N)(0.9964614)-Leukocyte transendothelial migration(K)(0.9979648)-MAPK signaling pathway(K)(0.9988886)-NOD-like receptor signaling pathway(K)(0.9948472)-Neurotrophin signaling pathway(K)(0.9960106)-Plasma membrane estrogen receptor signaling(N)(0.9973918)-Progesterone-mediated oocyte maturation(K)(0.9984766)-RIG-I-like receptor signaling pathway(K)(0.9923348)-Regulation of retinoblastoma protein(N)(0.9960302)-Shigellosis(K)(0.9959842)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9845648)-Signalling by NGF(R)(0.9980348)-TGF-beta signaling pathway(P)(0.9969844)-TNF receptor signaling pathway(N)(0.9961482)-Toll-like receptor signaling pathway(K)(0.995658)-mapkinase signaling pathway(B)(0.9295002) 192 PPP2CB 8p12 0 0 0 2 29 3 1342 0.6436 0 0.46969696969697 Chagas disease(K)(0.9969792)-EGF receptor signaling pathway(P)(0.9964802)-FGF signaling pathway(P)(0.9927172)-Glypican pathway(N)(0.9991154)-IFN-gamma pathway(N)(0.9975766)-Long-term depression(K)(0.9959516)-M Phase(R)(0.9980216)-Oocyte meiosis(K)(0.9960902)-Opioid Signalling(R)(0.9972342)-Signaling by Wnt(R)(0.9912718)-Signalling by NGF(R)(0.9976176)-TGF-beta signaling pathway(K)(0.9971718)-Tight junction(K)(0.9958648)-Wnt signaling pathway(K)(0.9911514)-Wnt signaling pathway(P)(0.9985312) 193 POMT2 14q24.3 0 0 0 0 33 3 3 0.6436 0 0.5 () 194 PIR 23p22.2 0 0 0 8 24 3 15 0.6436 0 0.484848484848485 y branching of actin filaments(B)(0.9984502) 195 PTPLA 10p12.33 0 0 0 0 9 3 21 0.6436 0 0.136363636363636 Biosynthesis of unsaturated fatty acids(K)(0.9985534) 196 PDK3 23p22.11 0 0 0 7 25 3 11 0.6436 0 0.484848484848485 Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9990304) 197 GH1 17q23.3 3 0 0 0 18 3 653 0.6436 0 0.318181818181818 Cytokine-cytokine receptor interaction(K)(0.9986416)-Jak-STAT signaling pathway(K)(0.9980248)-Neuroactive ligand-receptor interaction(K)(0.9980744)-akt signaling pathway(B)(0.9814094)-growth hormone signaling pathway(B)(0.9510836)-mtor signaling pathway(B)(0.9967392)-trefoil factors initiate mucosal healing(B)(0.9980982) 198 SHMT1 17p11.2 0 0 1 0 36 3 1130 0.6436 0 0.560606060606061 Glycine, serine and threonine metabolism(K)(0.9973508)-Metabolic pathways(K)(0.9986098)-One carbon pool by folate(K)(0.9966874) 199 ACACB 12q24.11 1 0 0 0 24 3 1346 0.6436 0 0.378787878787879 Activated AMPK stimulates fatty-acid oxidation in muscle(R)(0.8571422)-Adipocytokine signaling pathway(K)(0.9966754)-Insulin signaling pathway(K)(0.9981388)-Metabolic pathways(K)(0.99857)-Metabolism of lipids and lipoproteins(R)(0.9978916)-Pyruvate metabolism(K)(0.9971064) 200 ATP1B4 23q24 1 0 0 5 23 3 287 0.6436 0 0.439393939393939 Aldosterone-regulated sodium reabsorption(K)(0.9958798)-Cardiac muscle contraction(K)(0.9987298)-Gastric acid secretion(K)(0.997008)-Pancreatic secretion(K)(0.9975102)-Proximal tubule bicarbonate reclamation(K)(0.993096)-Salivary secretion(K)(0.9981462) 201 OR51Q1 11p15.4 0 0 0 1 26 3 413 0.6436 0 0.409090909090909 Olfactory Signaling Pathway(R)(0.9988262)-Olfactory transduction(K)(0.9993508) 202 SMARCE1 17q21.2 0 0 0 0 28 3 440 0.6436 0 0.424242424242424 Androgen-mediated signaling(N)(0.9780134)-Wnt signaling pathway(P)(0.9991538)-control of gene expression by vitamin d receptor(B)(0.9946046)-the information processing pathway at the ifn beta enhancer(B)(0.9972638) 203 CCND1 11q13.2 0 1 0 0 14 3 1735 0.6436 1 0.227272727272727 Androgen-mediated signaling(N)(0.9328984)-AndrogenReceptor(C)(0.9921818)-BMP receptor signaling(N)(0.9922646)-Cell cycle(K)(0.9962762)-Focal adhesion(K)(0.9984008)-Glioma(K)(0.8898496)-Glypican pathway(N)(0.9877336)-IFN-gamma pathway(N)(0.9816642)-Jak-STAT signaling pathway(K)(0.9985892)-Nectin adhesion pathway(N)(0.996087)-Pathways in cancer(K)(0.9965524)-Prostate cancer(K)(0.9909108)-Regulation of Telomerase(N)(0.9942222)-Regulation of retinoblastoma protein(N)(0.997569)-S Phase(R)(0.8286122)-TGFBR(C)(0.9981258)-Viral myocarditis(K)(0.9947406)-Wnt signaling pathway(K)(0.988316)-Wnt signaling pathway(P)(0.9995218)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.988199)-p53 signaling pathway(K)(0.995288)-p75(NTR)-mediated signaling(N)(0.9977874) 204 DUSP1 5q35.1 0 0 0 1 27 3 1052 0.6436 0 0.424242424242424 BMP receptor signaling(N)(0.9953782)-EGFR1(C)(0.9968288)-Fc-epsilon receptor I signaling in mast cells(N)(0.9897348)-Glypican pathway(N)(0.9944974)-IFN-gamma pathway(N)(0.9965242)-IL1-mediated signaling events(N)(0.9969282)-MAPK signaling pathway(K)(0.997909)-Oxidative stress response(P)(0.9919506)-Plasma membrane estrogen receptor signaling(N)(0.9979626)-TNF receptor signaling pathway(N)(0.9981068)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9871828)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9982804)-nfat and hypertrophy of the heart (B)(0.9967476)-nitric oxide signaling pathway(B)(0.9913812)-protein kinase a at the centrosome(B)(0.982506)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.9971274)-regulation of eif-4e and p70s6 kinase(B)(0.9740614)-regulation of pgc-1a(B)(0.985582)-t cell receptor signaling pathway(B)(0.9894176) 205 ARFIP2 11p15.4 0 0 0 1 25 3 843 0.6436 0 0.393939393939394 Glypican pathway(N)(0.999356)-Huntington disease(P)(0.9985984)-IGF1 pathway(N)(0.9608908)-Proteogylcan syndecan-mediated signaling events(N)(0.9976256)-TRAIL signaling pathway(N)(0.9977348)-rac1 cell motility signaling pathway(B)(0.9940076) 206 NAT1 8p22 0 0 0 1 25 3 1143 0.6436 0 0.393939393939394 Biological oxidations(R)(0.9983088)-Metabolic pathways(K)(0.9990096) 207 INSR 19p13.2 0 0 0 0 25 3 957 0.6436 0 0.378787878787879 Adherens junction(K)(0.9971316)-Aldosterone-regulated sodium reabsorption(K)(0.998879)-Endothelins(N)(0.996666)-Glypican pathway(N)(0.9984054)-IFN-gamma pathway(N)(0.9982966)-Insulin signaling pathway(K)(0.998194)-PI3 kinase pathway(P)(0.9782866)-Proteogylcan syndecan-mediated signaling events(N)(0.9976686)-Signaling events mediated by PTP1B(N)(0.994929)-TRAIL signaling pathway(N)(0.9964338)-Type II diabetes mellitus(K)(0.9965348) 208 ONECUT1 15q21.2 0 0 0 1 30 3 71 0.6436 0 0.46969696969697 FOXM1 transcription factor network(N)(0.9983778)-Regulation of beta-cell development(R)(0.9987606) 209 FADS2 11q12.2 0 0 0 0 11 3 100 0.6436 0 0.166666666666667 PPAR signaling pathway(K)(0.9990868)-alpha-Linolenic acid metabolism(K)(0.9949186) 210 POLD2 7p13 0 0 0 0 8 3 1407 0.6436 0 0.121212121212121 DNA Repair(R)(0.9985774)-Homologous recombination(K)(0.9569462)-Metabolic pathways(K)(0.9990408)-Purine metabolism(K)(0.9973796)-Telomere Maintenance(R)(0.9960784) 211 DVL2 17p13.1 0 0 0 1 30 3 577 0.6436 0 0.46969696969697 Alzheimer disease-presenilin pathway(P)(0.9984872)-Melanogenesis(K)(0.9989168)-Notch signaling pathway(K)(0.9934234)-Pathways in cancer(K)(0.9980624)-Wnt signaling pathway(K)(0.9982146)-Wnt(C)(0.996506) 212 PAOX 10q26.3 0 0 0 0 29 3 78 0.6436 0 0.439393939393939 Peroxisome(K)(0.9993646) 213 GARS 7p15.1 2 0 1 0 5 3 44 0.6436 0 0.121212121212121 () 214 HSPA5 9q33.3 0 0 0 0 21 3 418 0.6436 0 0.318181818181818 Antigen processing and presentation(K)(0.9979452)-Apoptosis signaling pathway(P)(0.9975714)-Further platelet releasate(R)(0.9973104)-Parkinson disease(P)(0.9973632)-Prion diseases(K)(0.9988904)-Protein export(K)(0.9979856)-Protein processing in endoplasmic reticulum(K)(0.999023)-prion pathway(B)(0.9925236) 215 GRK1 13q34 0 0 1 0 23 3 519 0.6436 0 0.363636363636364 Chemokine signaling pathway(K)(0.9989074)-Endocytosis(K)(0.9986594)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9973642)-Phototransduction(K)(0.9985042)-Visual signal transduction: Rods(N)(0.89044) 216 TLR3 4q35.1 0 0 0 5 29 3 175 0.6436 0 0.515151515151515 Toll-like receptor signaling pathway(K)(0.998654)-lectin induced complement pathway(B)(0.9794186)-toll-like receptor pathway(B)(0.9986762) 217 POLE 12q24.33 0 0 0 0 21 3 1391 0.6436 0 0.318181818181818 Base excision repair(K)(0.9921444)-DNA Repair(R)(0.9977362)-G1/S Transition(R)(0.9407138)-Metabolic pathways(K)(0.998883)-Nucleotide excision repair(K)(0.9970642)-Purine metabolism(K)(0.998985)-Pyrimidine metabolism(K)(0.9939882)-S Phase(R)(0.9364408)-Telomere Maintenance(R)(0.9967058) 218 PIK3R5 17p13.1 0 0 0 1 36 3 1374 0.6436 0 0.560606060606061 Aldosterone-regulated sodium reabsorption(K)(0.996748)-Amoebiasis(K)(0.995996)-Apoptosis(K)(0.997471)-B cell receptor signaling pathway(K)(0.991164)-Bacterial invasion of epithelial cells(K)(0.9916986)-Chagas disease(K)(0.99266)-Chemokine signaling pathway(K)(0.9977542)-ErbB signaling pathway(K)(0.9939538)-Fc gamma R-mediated phagocytosis(K)(0.9950304)-Focal adhesion(K)(0.9962746)-Insulin signaling pathway(K)(0.9979098)-Jak-STAT signaling pathway(K)(0.9993716)-Leukocyte transendothelial migration(K)(0.9989158)-Natural killer cell mediated cytotoxicity(K)(0.9968386)-Neurotrophin signaling pathway(K)(0.9980008)-Pathways in cancer(K)(0.9992724)-Phosphatidylinositol signaling system(K)(0.9970208)-Progesterone-mediated oocyte maturation(K)(0.9949092)-Prostate cancer(K)(0.980533)-Regulation of actin cytoskeleton(K)(0.9985938)-T cell receptor signaling pathway(K)(0.9950612)-Toll-like receptor signaling pathway(K)(0.9927402)-Type II diabetes mellitus(K)(0.996566)-VEGF signaling pathway(K)(0.9775706)-mTOR signaling pathway(K)(0.9930018) 219 ATP6V1E1 22q11.21 1 0 0 0 20 3 1330 0.6436 0 0.303030303030303 Collecting duct acid secretion(K)(0.8451838)-Epithelial cell signaling in Helicobacter pylori infection(K)(0.9980764)-Metabolic pathways(K)(0.9977086)-Oxidative phosphorylation(K)(0.9896646)-Phagosome(K)(0.9987308)-Vibrio cholerae infection(K)(0.9948464) 220 G6PD 23q28 0 0 1 2 27 3 1152 0.6436 0 0.454545454545455 Glutathione metabolism(K)(0.9982996)-Metabolic pathways(K)(0.999074)-Pentose phosphate pathway(K)(0.9390754) 221 OGDH 7p13 1 0 0 0 10 3 1259 0.6436 0 0.166666666666667 Glucose Regulation of Insulin Secretion(R)(0.9980108)-Lysine degradation(K)(0.9985696)-Metabolic pathways(K)(0.9985042)-Metabolism of amino acids(R)(0.9977504)-Pyruvate metabolism and TCA cycle(R)(0.9782654) 222 SMPD1 11p15.4 0 0 0 1 25 3 1673 0.6436 0 0.393939393939394 IL2-mediated signaling events(N)(0.9972632)-Lysosome(K)(0.9983204)-Metabolic pathways(K)(0.9981028)-Sphingolipid metabolism(K)(0.9930964)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9975706)-TNF receptor signaling pathway(N)(0.9976964)-TRAIL signaling pathway(N)(0.9985946)-phospholipids as signalling intermediaries(B)(0.9950474) 223 RHOBTB2 8p21.3 1 0 0 2 35 3 261 0.6436 0 0.560606060606061 Signaling by Rho GTPases(R)(0.9969424)-Ubiquitin mediated proteolysis(K)(0.9991622) 224 ABCC1 16p13.11 0 1 0 1 23 3 44 0.6436 0 0.378787878787879 ABC transporters(K)(0.9989696) 225 PTK2B 8p21.2 0 0 0 2 37 3 1219 0.6436 0 0.590909090909091 Alpha-synuclein signaling(N)(0.9915884)-Calcium signaling pathway(K)(0.998045)-Chemokine signaling pathway(K)(0.9978844)-EGFR1(C)(0.9966988)-Endothelins(N)(0.9954952)-GnRH signaling pathway(K)(0.9930714)-IL2-mediated signaling events(N)(0.9974844)-Integrin signalling pathway(P)(0.9986094)-Integrins in angiogenesis(N)(0.9952292)-LPA receptor mediated events(N)(0.991971)-Leukocyte transendothelial migration(K)(0.9991418)-Natural killer cell mediated cytotoxicity(K)(0.9974334)-Proteogylcan syndecan-mediated signaling events(N)(0.9986556)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9969734) 226 EHMT1 9q34.3 0 0 0 0 27 3 44 0.6436 0 0.409090909090909 Lysine degradation(K)(0.9971782) 227 AMY2B 1p21.1 1 0 0 0 9 3 1202 0.6436 0 0.151515151515152 Metabolic pathways(K)(0.9991394)-Pancreatic secretion(K)(0.998863) 228 AP1G1 16q22.3 1 0 0 0 18 3 264 0.6436 0 0.287878787878788 Host Interactions of HIV factors(R)(0.9988162)-Lysosome(K)(0.998899)-Membrane Trafficking(R)(0.9974558) 229 ARHGEF7 13q34 0 0 1 0 24 3 902 0.6436 0 0.378787878787879 Glypican pathway(N)(0.999429)-Regulation of actin cytoskeleton(K)(0.9973492)-Signaling by EGFR(R)(0.9980816)-Signaling by Rho GTPases(R)(0.9984626)-TRAIL signaling pathway(N)(0.995564)-agrin in postsynaptic differentiation(B)(0.995839) 230 ACCN1 17q12 1 0 2 1 38 3 52 0.6436 0 0.636363636363636 Taste transduction(K)(0.9992204) 231 SEMA6B 19p13.3 1 0 0 0 30 3 129 0.6436 0 0.46969696969697 Axon guidance(K)(0.9980904) 232 DAO 12q24.11 0 0 0 0 24 2 1173 0.6436 0 0.363636363636364 Glycine, serine and threonine metabolism(K)(0.9936052)-Metabolic pathways(K)(0.998707)-Peroxisome(K)(0.9977728) 233 TLR4 9q33.1 0 0 0 0 19 2 517 0.6436 0 0.287878787878788 Amoebiasis(K)(0.9995504)-Chagas disease(K)(0.999624)-Innate Immunity Signaling(R)(0.9586772)-Leishmaniasis(K)(0.8935248)-Malaria(K)(0.9981006)-Pathogenic Escherichia coli infection(K)(0.9988382)-Phagosome(K)(0.9984938)-Toll-like receptor signaling pathway(K)(0.9978312)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9931296) 234 MTMR1 23q28 0 0 1 2 26 2 1131 0.6436 0 0.439393939393939 Fructose and mannose metabolism(K)(0.9963014)-Metabolic pathways(K)(0.9976548)-Riboflavin metabolism(K)(0.9935636) 235 AR 23q12 0 0 0 5 21 2 1028 0.6436 0 0.393939393939394 Alpha6Beta4Integrin(C)(0.9932102)-Androgen-mediated signaling(N)(0.9813056)-AndrogenReceptor(C)(0.9918416)-FOXA transcription factor networks(N)(0.9798596)-Glypican pathway(N)(0.9972862)-IFN-gamma pathway(N)(0.9977238)-Oocyte meiosis(K)(0.9961922)-Pathways in cancer(K)(0.9986556)-Prostate cancer(K)(0.9926388)-TGFBR(C)(0.996621) 236 CD38 4p15.32 0 0 1 1 27 2 1441 0.6436 0 0.439393939393939 Calcium signaling pathway(K)(0.9980066)-Hematopoietic cell lineage(K)(0.9963644)-Metabolic pathways(K)(0.9985282)-Nicotinate and nicotinamide metabolism(K)(0.9386724)-Pancreatic secretion(K)(0.9987198)-Salivary secretion(K)(0.9950286) 237 ACAD8 11q25 0 0 0 3 27 2 1180 0.6436 0 0.454545454545455 Metabolic pathways(K)(0.9987218)-Metabolism of amino acids(R)(0.9993242) 238 RASA1 5q14.3 0 0 0 3 32 2 1275 0.6436 0 0.53030303030303 Angiogenesis(P)(0.9936296)-Angiopoietin receptor Tie2-mediated signaling(N)(0.9094048)-Axon guidance(K)(0.9990056)-EGF receptor signaling pathway(P)(0.9934438)-EGFR1(C)(0.9988012)-FGF signaling pathway(P)(0.975232)-Fc-epsilon receptor I signaling in mast cells(N)(0.9877744)-Glypican pathway(N)(0.9986368)-IL2-mediated signaling events(N)(0.9966266)-Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade(P)(0.9802706)-KitReceptor(C)(0.9917488)-MAPK signaling pathway(K)(0.9993422)-Nectin adhesion pathway(N)(0.9983716)-Plasma membrane estrogen receptor signaling(N)(0.9898572)-Proteogylcan syndecan-mediated signaling events(N)(0.998768)-Signaling by Aurora kinases(N)(0.9582702)-Signaling by PDGF(R)(0.9906566)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9964838)-Signaling events regulated by Ret tyrosine kinase(N)(0.9948916)-Sphingosine 1-phosphate (S1P) pathway(N)(0.8743602)-TRAIL signaling pathway(N)(0.9971568)-p75(NTR)-mediated signaling(N)(0.9972756)-tpo signaling pathway(B)(0.9629486) 239 B3GNT7 2q37.1 0 0 0 0 16 2 15 0.6436 0 0.242424242424242 Glycosaminoglycan biosynthesis - keratan sulfate(K)(0.9972228) 240 PAX5 9p13.2 0 0 1 0 16 2 25 0.6436 1 0.257575757575758 ID(C)(0.9987278) 241 HSD17B4 5q23.1 0 0 0 1 32 2 1259 0.6436 0 0.5 Metabolic pathways(K)(0.9991724)-Metabolism of lipids and lipoproteins(R)(0.998409)-Peroxisome(K)(0.9957658)-Primary bile acid biosynthesis(K)(0.9484024)-mechanism of gene regulation by peroxisome proliferators via ppara(B)(0.9988142) 242 IL10RA 11q23.3 0 0 0 0 22 2 370 0.6436 0 0.333333333333333 Cytokine-cytokine receptor interaction(K)(0.999305)-Interleukin signaling pathway(P)(0.9979868)-Jak-STAT signaling pathway(K)(0.9986452)-il-10 anti-inflammatory signaling pathway(B)(0.9962502) 243 PER1 17p13.1 0 0 0 1 36 2 30 0.6436 1 0.560606060606061 Circadian rhythm - mammal(K)(0.9990724)-Circadian rhythm pathway(N)(0.9958954) 244 TAAR8 6q23.2 0 0 1 0 4 2 381 0.6436 0 0.0757575757575758 Class A/1 (Rhodopsin-like receptors)(R)(0.9972746)-Neuroactive ligand-receptor interaction(K)(0.998811)-Receptor-ligand complexes bind G proteins(R)(0.9953718) 245 QDPR 4p15.32 0 0 0 1 37 2 1179 0.6436 0 0.575757575757576 Metabolic pathways(K)(0.9993476)-Metabolism of amino acids(R)(0.998769) 246 SLC30A5 5q13.2 0 0 0 3 30 2 49 0.6436 0 0.5 Insulin Synthesis and Secretion(R)(0.999098) 247 HNRNPM 19p13.2 0 0 0 0 19 2 353 0.6436 0 0.287878787878788 Formation and Maturation of mRNA Transcript(R)(0.9990368)-Influenza Life Cycle(R)(0.9986814)-Spliceosome(K)(0.9982672) 248 GJD2 15q14 0 0 0 2 29 2 146 0.6436 0 0.46969696969697 Gap junction trafficking and regulation(R)(0.9982584)-Gap junction(K)(0.9981334)-Synaptic Transmission(R)(0.9978128) 249 LNPEP 5q15 0 0 0 4 33 2 426 0.6436 0 0.560606060606061 Plasma membrane estrogen receptor signaling(N)(0.9990646)-Proteogylcan syndecan-mediated signaling events(N)(0.998335)-Renin-angiotensin system(K)(0.9971974) 250 SULT2B1 19q13.32 0 0 0 0 13 2 115 0.6436 0 0.196969696969697 Biological oxidations(R)(0.998235)-Steroid hormone biosynthesis(K)(0.9980954)-Sulfur metabolism(K)(0.9618912) 251 AXIN1 16p13.3 0 0 1 1 24 2 1163 0.6436 0 0.393939393939394 Angiogenesis(P)(0.9976428)-Glypican pathway(N)(0.9964796)-IFN-gamma pathway(N)(0.9976914)-Pathways in cancer(K)(0.9967924)-Presenilin action in Notch and Wnt signaling(N)(0.8903802)-Signaling by Wnt(R)(0.993425)-TGFBR(C)(0.9984362)-Wnt signaling pathway(K)(0.9971088)-Wnt signaling pathway(P)(0.998315)-Wnt(C)(0.9965934)-inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages(B)(0.9800974)-multi-step regulation of transcription by pitx2(B)(0.8637046)-segmentation clock(B)(0.9949418) 252 SLC2A4 17p13.1 0 0 0 1 30 2 637 0.6436 0 0.46969696969697 Adipocytokine signaling pathway(K)(0.9970302)-Insulin signaling pathway(K)(0.9993556)-Metabolism of carbohydrates(R)(0.9975822)-Metabolism of vitamins and cofactors(R)(0.9977744)-Plasma membrane estrogen receptor signaling(N)(0.9973892)-Proteogylcan syndecan-mediated signaling events(N)(0.9976818)-Type II diabetes mellitus(K)(0.9941012) 253 PLA2G2F 1p36.12 0 0 1 0 17 2 1602 0.6436 0 0.272727272727273 Arachidonic acid metabolism(K)(0.9965586)-Fc epsilon RI signaling pathway(K)(0.9958612)-Glycerophospholipid metabolism(K)(0.9959662)-GnRH signaling pathway(K)(0.9919804)-Long-term depression(K)(0.9960022)-MAPK signaling pathway(K)(0.9993108)-Metabolic pathways(K)(0.9989128)-Pancreatic secretion(K)(0.9973454)-VEGF signaling pathway(K)(0.9962726)-Vascular smooth muscle contraction(K)(0.9983454) 254 GANAB 11q12.3 0 0 0 0 11 2 1281 0.6436 0 0.166666666666667 Metabolic pathways(K)(0.9994588)-N-Glycan biosynthesis(K)(0.8269042)-Protein processing in endoplasmic reticulum(K)(0.9990642) 255 CSNK1D 17q25.3 0 0 0 0 16 2 604 0.6436 0 0.242424242424242 Circadian rhythm - mammal(K)(0.9962424)-FoxO family signaling(N)(0.9971558)-G2/M Transition(R)(0.99789)-Gap junction(K)(0.998883)-Hedgehog signaling pathway(K)(0.9939882)-Signaling events mediated by the Hedgehog family(N)(0.9954394)-Wnt signaling pathway(P)(0.9987478)-Wnt(C)(0.9975068)-regulation of ck1/cdk5 by type 1 glutamate receptors(B)(0.987481) 256 CYP2E1 10q26.3 0 0 0 0 26 2 1182 0.6436 0 0.393939393939394 Arachidonic acid metabolism(K)(0.998012)-Drug metabolism - cytochrome P450(K)(0.9348692)-Metabolic pathways(K)(0.9979574)-Metabolism of xenobiotics by cytochrome P450(K)(0.9975584)-eicosanoid metabolism(B)(0.9959808) 257 PTEN 10q23.31 5 0 1 4 16 2 1456 0.6436 1 0.378787878787879 Endothelins(N)(0.994763)-Focal adhesion(K)(0.9982576)-Glypican pathway(N)(0.9050762)-Hypoxia response via HIF activation(P)(0.934007)-IFN-gamma pathway(N)(0.999146)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9950296)-Inositol phosphate metabolism(K)(0.9791816)-Nectin adhesion pathway(N)(0.9919126)-Pathways in cancer(K)(0.9983456)-Phosphatidylinositol signaling system(K)(0.9986952)-Proteogylcan syndecan-mediated signaling events(N)(0.9961878)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.993282)-Signalling by NGF(R)(0.9984352)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9942302)-TCR signaling in naive CD4+ T cells(N)(0.997674)-TCR signaling(R)(0.8850094)-TRAIL signaling pathway(N)(0.993434)-Tight junction(K)(0.9982524)-ctcf: first multivalent nuclear factor(B)(0.9929662)-mtor signaling pathway(B)(0.9260462)-p53 pathway(P)(0.9515716)-p53 signaling pathway(K)(0.9960036)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.9795734) 258 PIK3CB 3q22.3 0 1 0 0 5 2 1726 0.6436 0 0.0909090909090909 Aldosterone-regulated sodium reabsorption(K)(0.9047448)-Amoebiasis(K)(0.9974556)-Cell surface interactions at the vascular wall(R)(0.996893)-EGFR1(C)(0.9986472)-Endothelin signaling pathway(P)(0.9392442)-Focal adhesion(K)(0.936011)-Insulin signaling pathway(K)(0.995699)-Jak-STAT signaling pathway(K)(0.9307138)-Neurotrophin signaling pathway(K)(0.9966436)-Pathways in cancer(K)(0.9394384)-Phosphatidylinositol signaling system(K)(0.9667442)-Regulation of actin cytoskeleton(K)(0.9610656)-Signalling by NGF(R)(0.8058326) 259 ATF5 19q13.33 0 0 0 0 14 2 22 0.6436 0 0.212121212121212 Signaling events mediated by PRL(N)(0.9991066) 260 HMGCS2 1p12 1 2 2 0 5 2 1225 0.6436 0 0.151515151515152 Metabolic pathways(K)(0.999514)-Metabolism of lipids and lipoproteins(R)(0.9987402)-PPAR signaling pathway(K)(0.9959474) 261 CASP8 2q33.1 2 0 0 0 12 2 1467 0.6436 0 0.212121212121212 Alzheimer's disease(K)(0.9978964)-Androgen-mediated signaling(N)(0.936672)-Apoptosis signaling pathway(P)(0.9795548)-Apoptosis(K)(0.9165608)-Apoptosis(R)(0.9958744)-Chagas disease(K)(0.9957726)-FAS signaling pathway(P)(0.9886326)-Huntington disease(P)(0.9980508)-Huntington's disease(K)(0.9920312)-Integrins in angiogenesis(N)(0.9950692)-NOD-like receptor signaling pathway(K)(0.9959434)-Pathways in cancer(K)(0.9988776)-RIG-I-like receptor signaling pathway(K)(0.9959392)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9930864)-TNF alpha/NF-kB(C)(0.9988118)-TNF receptor signaling pathway(N)(0.9924468)-Toll-like receptor signaling pathway(K)(0.997827)-Viral myocarditis(K)(0.9965854)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9495732)-p53 signaling pathway(K)(0.9955386) 262 GNB1 1p36.33 0 0 0 0 19 2 1721 0.6436 0 0.287878787878788 Androgen-mediated signaling(N)(0.9617452)-Chemokine signaling pathway(K)(0.9971248)-Formation of Platelet plug(R)(0.9972008)-Glypican pathway(N)(0.9482474)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.982586)-IGF1 pathway(N)(0.8235616)-LPA receptor mediated events(N)(0.9932396)-Olfactory Signaling Pathway(R)(0.9984776)-Opioid Signalling(R)(0.9975784)-Phototransduction(K)(0.9874602)-Proteogylcan syndecan-mediated signaling events(N)(0.9935448)-Receptor-ligand complexes bind G proteins(R)(0.9968258)-Signaling events mediated by HDAC Class I(N)(0.9957978)-Signaling events mediated by the Hedgehog family(N)(0.993131)-Taste transduction(K)(0.9976568)-Thromboxane A2 receptor signaling(N)(0.9928704)-Wnt signaling pathway(P)(0.9989874)-actions of nitric oxide in the heart(B)(0.9811886)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9365336)-ccr3 signaling in eosinophils(B)(0.9095746)-chrebp regulation by carbohydrates and camp(B)(0.9894278)-ion channels and their functional role in vascular endothelium(B)(0.9923484)-phospholipids as signalling intermediaries(B)(0.9926316)-pkc-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase(B)(0.9062758) 263 IGF1 12q23.2 0 0 0 0 22 2 1226 0.6436 0 0.333333333333333 Aldosterone-regulated sodium reabsorption(K)(0.9963304)-Dilated cardiomyopathy(K)(0.9940458)-Focal adhesion(K)(0.9980032)-Formation of Platelet plug(R)(0.9973018)-Integrins in angiogenesis(N)(0.9931172)-Long-term depression(K)(0.9974316)-Oocyte meiosis(K)(0.9985058)-Pathways in cancer(K)(0.9989548)-Plasma membrane estrogen receptor signaling(N)(0.9554106)-Progesterone-mediated oocyte maturation(K)(0.9854174)-Prostate cancer(K)(0.9905274)-Regulation of IGF Activity by IGFBP(R)(0.9798472)-Sphingosine 1-phosphate (S1P) pathway(N)(0.915214)-TNF receptor signaling pathway(N)(0.9988358)-TRAIL signaling pathway(N)(0.9945476)-mTOR signaling pathway(K)(0.9975634)-nfat and hypertrophy of the heart (B)(0.9939946)-p53 signaling pathway(K)(0.997479)-regulation of bad phosphorylation(B)(0.8500566)-skeletal muscle hypertrophy is regulated via akt-mtor pathway(B)(0.939039) 264 NR1I3 1q23.3 0 0 7 0 1 2 30 0.6436 0 0.121212121212121 NR transcription pathway(R)(0.996783) 265 PDCD1 2q37.3 0 0 0 1 20 2 234 0.6436 0 0.318181818181818 Cell adhesion molecules (CAMs)(K)(0.9989264)-T cell receptor signaling pathway(K)(0.9988334) 266 RARS 5q35.1 0 0 0 1 31 2 44 0.6436 0 0.484848484848485 Aminoacyl-tRNA biosynthesis(K)(0.9988786) 267 KIF20A 5q31.2 0 0 0 1 34 2 174 0.6436 0 0.53030303030303 M Phase(R)(0.9960728)-Signaling by Aurora kinases(N)(0.9943948) 268 TGFB1 19q13.2 0 0 0 0 12 2 1571 0.6436 0 0.181818181818182 Amoebiasis(K)(0.9896792)-Cell cycle(K)(0.9959066)-Chagas disease(K)(0.995764)-Cytokine-cytokine receptor interaction(K)(0.9987748)-Endocytosis(K)(0.998457)-Formation of Platelet plug(R)(0.9854722)-Hypertrophic cardiomyopathy (HCM)(K)(0.94844)-IL12-mediated signaling events(N)(0.9647516)-MAPK signaling pathway(K)(0.9995982)-Malaria(K)(0.9867648)-Pathways in cancer(K)(0.999118)-Proteogylcan syndecan-mediated signaling events(N)(0.9808108)-Renal cell carcinoma(K)(0.8770046)-Retinoic acid receptors-mediated signaling(N)(0.9961876)-TGF-beta signaling pathway(K)(0.9946212)-TGF-beta signaling pathway(P)(0.9947764)-TGFBR(C)(0.998102) 269 MTA3 2p21 0 0 0 0 8 2 19 0.6436 0 0.121212121212121 downregulated of mta-3 in er-negative breast tumors(B)(0.9904816) 270 XRCC3 14q32.33 0 0 0 0 29 2 28 0.6436 0 0.439393939393939 Homologous recombination(K)(0.997219) 271 PDX1 13q12.2 0 0 0 0 31 2 182 0.6436 0 0.46969696969697 FOXA transcription factor networks(N)(0.9936292)-Insulin Synthesis and Secretion(R)(0.9989496)-Regulation of beta-cell development(R)(0.9887612)-Type II diabetes mellitus(K)(0.998553) 272 AMT 3p21.31 0 0 1 0 29 2 1142 0.6436 0 0.454545454545455 Glycine, serine and threonine metabolism(K)(0.9984908)-Metabolic pathways(K)(0.9988776)-Nitrogen metabolism(K)(0.9974554)-One carbon pool by folate(K)(0.992189) 273 GTF2F2 13q14.12 0 0 0 2 32 2 414 0.6436 0 0.515151515151515 AndrogenReceptor(C)(0.9985134)-Basal transcription factors(K)(0.9927648)-Formation and Maturation of mRNA Transcript(R)(0.9979702)-HIV Life Cycle(R)(0.997057)-Influenza Life Cycle(R)(0.9975284)-Transcription(R)(0.9984758)-mRNA Processing(R)(0.9881484) 274 MED27 9q34.13 0 0 0 0 28 2 33 0.6436 0 0.424242424242424 Generic Transcription Pathway(R)(0.9972684) 275 ARFGEF2 20q13.13 1 0 0 0 8 2 248 0.6436 0 0.136363636363636 Metabolism of proteins(R)(0.9991448)-adp-ribosylation factor(B)(0.9978682)-thrombin signaling and protease-activated receptors(B)(0.9806356) 276 TARSL2 15q26.3 0 0 1 1 20 2 41 0.6436 0 0.333333333333333 Aminoacyl-tRNA biosynthesis(K)(0.9990604) 277 CYFIP1 15q11.2 0 0 0 1 23 2 337 0.6436 0 0.363636363636364 Huntington disease(P)(0.9984502)-Regulation of actin cytoskeleton(K)(0.9987718) 278 TH 11p15.5 0 0 0 1 30 2 1946 0.6436 0 0.46969696969697 Alpha-synuclein signaling(N)(0.9576862)-BMP receptor signaling(N)(0.9961438)-Glypican pathway(N)(0.9978976)-IFN-gamma pathway(N)(0.9971162)-IL1-mediated signaling events(N)(0.994577)-Metabolic pathways(K)(0.9986836)-Parkinson disease(P)(0.9976018)-Parkinson's disease(K)(0.9963392)-Plasma membrane estrogen receptor signaling(N)(0.9969974)-Synaptic Transmission(R)(0.997475)-TNF receptor signaling pathway(N)(0.998319)-Tyrosine metabolism(K)(0.9891452) 279 PGR 11q22.1 0 0 0 0 16 2 193 0.6436 0 0.242424242424242 NR transcription pathway(R)(0.996475)-Oocyte meiosis(K)(0.9984424)-Progesterone-mediated oocyte maturation(K)(0.997584)-how progesterone initiates the oocyte maturation(B)(0.994431) 280 RORA 15q22.2 0 0 0 2 28 2 101 0.6436 0 0.454545454545455 Circadian rhythm - mammal(K)(0.998546)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9993774) 281 NTN1 17p13.1 0 0 0 1 39 2 129 0.6436 0 0.606060606060606 Axon guidance(K)(0.998413) 282 JMJD2C 9p24.1 0 0 6 0 20 2 125 0.6436 0 0.393939393939394 Androgen-mediated signaling(N)(0.9956424) 283 COX8C 14q32.13 0 0 0 0 31 2 1336 0.6436 0 0.46969696969697 Alzheimer's disease(K)(0.9992186)-Cardiac muscle contraction(K)(0.9953288)-Huntington's disease(K)(0.9983286)-Metabolic pathways(K)(0.9989586)-Oxidative phosphorylation(K)(0.9970028)-Parkinson's disease(K)(0.997153) 284 ADRA1A 8p21.2 0 0 0 3 34 2 662 0.6436 0 0.560606060606061 Calcium signaling pathway(K)(0.9986822)-Class A/1 (Rhodopsin-like receptors)(R)(0.9984212)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9987102)-Neuroactive ligand-receptor interaction(K)(0.99851)-Receptor-ligand complexes bind G proteins(R)(0.9831736)-Salivary secretion(K)(0.9964932)-Vascular smooth muscle contraction(K)(0.9970144) 285 NOX1 23q22.1 0 0 0 4 26 2 260 0.6436 0 0.454545454545455 Leukocyte transendothelial migration(K)(0.9988282)-Phagosome(K)(0.9980468) 286 PSMA1 11p15.2 0 0 0 1 25 2 437 0.6436 0 0.393939393939394 Apoptosis(R)(0.9991862)-Cell Cycle Checkpoints(R)(0.9959666)-Host Interactions of HIV factors(R)(0.9973294)-Metabolism of amino acids(R)(0.9985044)-Parkinson disease(P)(0.9971942)-Proteasome(K)(0.9304392)-S Phase(R)(0.9988398)-Signaling by Wnt(R)(0.9959812) 287 TBP 6q27 0 0 0 0 21 2 659 0.6436 0 0.318181818181818 Basal transcription factors(K)(0.9924454)-Formation and Maturation of mRNA Transcript(R)(0.9956648)-HIV Life Cycle(R)(0.9935012)-Huntington disease(P)(0.9983718)-Huntington's disease(K)(0.9955746)-Regulation of retinoblastoma protein(N)(0.997468)-Transcription(R)(0.9980756)-Wnt(C)(0.9984126) 288 SLIT3 5q35.1 0 0 0 3 34 2 129 0.6436 0 0.560606060606061 Axon guidance(K)(0.997413) 289 ADORA2B 17p12 0 0 0 1 33 2 549 0.6436 0 0.515151515151515 Calcium signaling pathway(K)(0.9985644)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9954898)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9962762)-Neuroactive ligand-receptor interaction(K)(0.9988308)-Vascular smooth muscle contraction(K)(0.9984068) 290 AIM2 1q23.2 0 0 5 0 1 2 56 0.6436 0 0.0909090909090909 Cytosolic DNA-sensing pathway(K)(0.9988342) 291 SLC1A1 9p24.2 0 0 6 0 13 2 42 0.6436 0 0.287878787878788 Synaptic Transmission(R)(0.9974018) 292 RNF125 18q12.1 0 0 0 0 14 2 71 0.6436 0 0.212121212121212 RIG-I-like receptor signaling pathway(K)(0.999019) 293 NSFL1C 20p13 1 0 2 1 12 2 167 0.6436 0 0.227272727272727 Protein processing in endoplasmic reticulum(K)(0.9995764) 294 GYG2 23p22.33 0 0 0 8 33 2 108 0.6436 0 0.621212121212121 Metabolism of carbohydrates(R)(0.9986882) 295 PDE4B 1p31.3 1 0 1 1 8 2 223 0.6436 0 0.166666666666667 Opioid Signalling(R)(0.9966186)-Purine metabolism(K)(0.9989802) 296 MFSD8 4q28.2 0 0 1 0 22 2 121 0.6436 0 0.348484848484849 Lysosome(K)(0.9986988) 297 APOE 19q13.32 0 0 0 0 11 1 272 0.6436 0 0.166666666666667 Alzheimer's disease(K)(0.9991978)-Metabolism of lipids and lipoproteins(R)(0.9959108) 298 IFNA5 9p21.3 0 0 3 0 15 1 615 0.6436 0 0.272727272727273 Cytokine-cytokine receptor interaction(K)(0.9984012)-Cytosolic DNA-sensing pathway(K)(0.9940824)-Jak-STAT signaling pathway(K)(0.9981286)-Natural killer cell mediated cytotoxicity(K)(0.9979838)-RIG-I-like receptor signaling pathway(K)(0.9980938)-Regulation of autophagy(K)(0.9963952)-TCR signaling in naive CD8+ T cells(N)(0.997394)-Toll-like receptor signaling pathway(K)(0.9977006) 299 CYP2A13 19q13.2 0 0 1 0 16 1 1168 0.6436 0 0.257575757575758 Biological oxidations(R)(0.9980126)-Drug metabolism - cytochrome P450(K)(0.9662726)-Metabolic pathways(K)(0.9995356)-Retinol metabolism(K)(0.9556188) 300 CTH 1p31.1 0 0 0 0 10 1 1148 0.6436 0 0.151515151515152 Metabolic pathways(K)(0.9986532) 301 FGB 4q32.1 0 0 0 1 22 1 231 0.6436 0 0.348484848484849 Complement and coagulation cascades(K)(0.996105)-Formation of Fibrin Clot (Clotting Cascade)(R)(0.8691838)-Formation of Platelet plug(R)(0.9995676)-Integrin cell surface interactions(R)(0.998188) 302 DCTN1 2p13.1 1 0 0 0 6 1 399 0.6436 0 0.106060606060606 G2/M Transition(R)(0.9983724)-Huntington disease(P)(0.9978)-Huntington's disease(K)(0.9972194)-lissencephaly gene (lis1) in neuronal migration and development(B)(0.9871626) 303 DNTT 10q24.1 0 0 0 0 19 1 102 0.6436 0 0.287878787878788 Hematopoietic cell lineage(K)(0.9991652)-Non-homologous end-joining(K)(0.998318) 304 GALNT10 5q33.2 0 0 0 2 31 1 1121 0.6436 0 0.5 Metabolic pathways(K)(0.9974908) 305 IL4I1 19q13.33 0 0 0 0 14 1 1142 0.6436 0 0.212121212121212 Alanine, aspartate and glutamate metabolism(K)(0.953646)-Metabolic pathways(K)(0.999141)-Tryptophan metabolism(K)(0.9823058) 306 AKR1C4 10p15.1 0 0 2 0 8 1 1158 0.6436 0 0.151515151515152 Metabolic pathways(K)(0.9986372)-Metabolism of xenobiotics by cytochrome P450(K)(0.9660938) 307 LRPAP1 4p16.2 1 0 0 1 34 1 132 0.6436 0 0.53030303030303 Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9968618)-Reelin signaling pathway(N)(0.996509)-Signaling events mediated by the Hedgehog family(N)(0.9985052)-integrin signaling pathway(B)(0.9961468) 308 PML 15q24.1 0 0 0 0 27 1 1114 0.6436 1 0.409090909090909 Acute myeloid leukemia(K)(0.9749642)-Endocytosis(K)(0.9988076)-Glypican pathway(N)(0.9979398)-IFN-gamma pathway(N)(0.997305)-Pathways in cancer(K)(0.9986316)-TNF alpha/NF-kB(C)(0.9982222)-Ubiquitin mediated proteolysis(K)(0.9985626)-Vitamin D metabolism and pathway(P)(0.9754462)-p53 pathway(P)(0.9966056)-regulation of transcriptional activity by pml(B)(0.9956032) 309 GABRA5 15q12 0 0 0 2 26 1 283 0.6436 0 0.424242424242424 Neuroactive ligand-receptor interaction(K)(0.9987512)-gamma-aminobutyric acid receptor life cycle pathway(B)(0.9755516) 310 GTF2E1 3q13.33 1 0 0 0 3 1 288 0.6436 0 0.0606060606060606 Transcription(R)(0.996608) 311 ANP32A 15q23 0 0 0 0 26 1 12 0.6436 0 0.393939393939394 () 312 CD3E 11q23.3 0 0 0 0 18 1 586 0.6436 0 0.272727272727273 Chagas disease(K)(0.9978082)-Hematopoietic cell lineage(K)(0.9991248)-IL12-mediated signaling events(N)(0.9990548)-IL23-mediated signaling events(N)(0.9980306)-Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R)(0.9961628)-Primary immunodeficiency(K)(0.9981166)-T cell receptor signaling pathway(K)(0.9966066)-TCR signaling in naive CD4+ T cells(N)(0.9991938)-TCR signaling(R)(0.9962798)-activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor(B)(0.9724968)-role of mef2d in t-cell apoptosis(B)(0.9940032)-t cell receptor signaling pathway(B)(0.9893666) 313 CREM 10p11.21 0 0 0 0 12 1 914 0.6436 0 0.181818181818182 BMP receptor signaling(N)(0.9950208)-Endothelins(N)(0.9961244)-Glypican pathway(N)(0.9545698)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.996501)-IFN-gamma pathway(N)(0.9975938)-IL1-mediated signaling events(N)(0.9968218)-TCR signaling in naive CD4+ T cells(N)(0.994474)-TNF receptor signaling pathway(N)(0.9970848)-TRAIL signaling pathway(N)(0.9847608)-regulation of spermatogenesis by crem(B)(0.8944114) 314 AIFM1 23q25 0 0 0 6 22 1 497 0.6436 0 0.424242424242424 Apoptosis signaling pathway(P)(0.9943742)-Apoptosis(K)(0.998363)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9989716)-TNF receptor signaling pathway(N)(0.998688)-TRAIL signaling pathway(N)(0.9835254) 315 ABCB6 2q35 0 0 0 0 16 1 44 0.6436 0 0.242424242424242 ABC transporters(K)(0.998996) 316 PRKAG2 7q36.1 0 0 0 0 12 1 283 0.6436 0 0.181818181818182 Adipocytokine signaling pathway(K)(0.995746)-Hypertrophic cardiomyopathy (HCM)(K)(0.9589744)-Insulin signaling pathway(K)(0.9992364)-chrebp regulation by carbohydrates and camp(B)(0.996295) 317 SRP19 5q22.2 0 0 0 3 33 1 56 0.6436 0 0.545454545454545 Insulin Synthesis and Secretion(R)(0.9988998)-Protein export(K)(0.9970016) 318 SH3GL2 9p22.2 1 0 5 0 13 1 493 0.6436 0 0.287878787878788 EGFR1(C)(0.9971086)-Endocytosis(K)(0.9983766)-Membrane Trafficking(R)(0.9967264)-Signalling by NGF(R)(0.9977394) 319 MYH6 14q11.2 1 0 0 0 23 1 632 0.6436 0 0.363636363636364 Cardiac muscle contraction(K)(0.9961928)-Dilated cardiomyopathy(K)(0.996959)-Hypertrophic cardiomyopathy (HCM)(K)(0.9846282)-Muscle contraction(R)(0.997693)-Nicotinic acetylcholine receptor signaling pathway(P)(0.997008)-Tight junction(K)(0.9986026)-Viral myocarditis(K)(0.998198)-Wnt signaling pathway(P)(0.99852) 320 POMT1 9q34.13 0 0 0 0 23 1 3 0.6436 0 0.348484848484849 () 321 PANK3 5q35.1 0 0 0 1 31 1 1122 0.6436 0 0.484848484848485 Metabolic pathways(K)(0.9991028)-Pantothenate and CoA biosynthesis(K)(0.9436382) 322 MTMR2 11q21 0 0 0 0 15 1 1131 0.6436 0 0.227272727272727 Fructose and mannose metabolism(K)(0.9903224)-Metabolic pathways(K)(0.9979142)-Riboflavin metabolism(K)(0.9872278) 323 MAP2K3 17p11.2 0 0 1 1 38 1 1380 0.6436 0 0.606060606060606 Amyotrophic lateral sclerosis (ALS)(K)(0.9976976)-Apoptosis signaling pathway(P)(0.9922094)-BMP receptor signaling(N)(0.9978886)-Cellular roles of Anthrax toxin(N)(0.99492)-EGF receptor signaling pathway(P)(0.9947134)-EGFR1(C)(0.9964166)-FGF signaling pathway(P)(0.990494)-Fc epsilon RI signaling pathway(K)(0.9466952)-Glypican pathway(N)(0.994633)-GnRH signaling pathway(K)(0.9969182)-IFN-gamma pathway(N)(0.9975992)-IL1-mediated signaling events(N)(0.9868858)-IL12-mediated signaling events(N)(0.996055)-Integrin signalling pathway(P)(0.9981298)-MAPK signaling pathway(K)(0.9993978)-Oxidative stress response(P)(0.9851764)-Plasma membrane estrogen receptor signaling(N)(0.998264)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.996522)-TGFBR(C)(0.9982774)-TNF receptor signaling pathway(N)(0.9989874)-Toll-like receptor signaling pathway(K)(0.9968952)-fmlp induced chemokine gene expression in hmc-1 cells(B)(0.9892748)-keratinocyte differentiation(B)(0.9859856)-mapkinase signaling pathway(B)(0.9537046)-nfkb activation by nontypeable hemophilus influenzae(B)(0.9606762)-p75(NTR)-mediated signaling(N)(0.9977836) 324 MUC2 11p15.5 0 0 0 1 28 1 191 0.6436 0 0.439393939393939 Amoebiasis(K)(0.9984952)-Vibrio cholerae infection(K)(0.9989712)-nfkb activation by nontypeable hemophilus influenzae(B)(0.9961102)-trefoil factors initiate mucosal healing(B)(0.9991066) 325 MYL2 12q24.11 0 0 0 0 23 1 659 0.6436 0 0.348484848484849 Cardiac muscle contraction(K)(0.9973204)-Dilated cardiomyopathy(K)(0.9986638)-Focal adhesion(K)(0.9987086)-Hypertrophic cardiomyopathy (HCM)(K)(0.9649592)-Leukocyte transendothelial migration(K)(0.997453)-Muscle contraction(R)(0.997738)-Regulation of actin cytoskeleton(K)(0.9994358)-Tight junction(K)(0.9988924)-alk in cardiac myocytes(B)(0.9970378)-ccr3 signaling in eosinophils(B)(0.9953544)-nfat and hypertrophy of the heart (B)(0.9937636)-rac1 cell motility signaling pathway(B)(0.9957754) 326 HK1 10q21.3 0 0 0 0 16 1 1383 0.6436 0 0.242424242424242 Amino sugar and nucleotide sugar metabolism(K)(0.9926084)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.9970648)-Insulin signaling pathway(K)(0.9990892)-Metabolic pathways(K)(0.9989052)-Metabolism of carbohydrates(R)(0.9969648)-Type II diabetes mellitus(K)(0.996324) 327 DYNLT1 6q25.3 0 0 0 0 20 1 193 0.6436 0 0.303030303030303 Lissencephaly gene (LIS1) in neuronal migration and development(N)(0.9990374)-p75(NTR)-mediated signaling(N)(0.9983908) 328 WNT5A 3p14.3 0 0 0 0 33 1 1206 0.6436 0 0.5 Alzheimer disease-presenilin pathway(P)(0.9983248)-Angiogenesis(P)(0.9937528)-Glypican pathway(N)(0.995809)-Hedgehog signaling pathway(K)(0.997226)-Melanogenesis(K)(0.995957)-Pathways in cancer(K)(0.9986856)-Proteogylcan syndecan-mediated signaling events(N)(0.9943534)-Wnt signaling pathway(K)(0.9987408)-Wnt signaling pathway(P)(0.998856)-Wnt(C)(0.9986396) 329 BSG 19p13.3 0 0 1 3 32 1 503 0.6436 0 0.545454545454545 Cell surface interactions at the vascular wall(R)(0.9982972)-Integrin cell surface interactions(R)(0.996127)-Metabolism of carbohydrates(R)(0.9968076)-Proteogylcan syndecan-mediated signaling events(N)(0.9970516)-Pyruvate metabolism and TCA cycle(R)(0.997033) 330 MMP2 16q12.2 1 0 0 1 17 1 933 0.6436 0 0.272727272727273 Alzheimer disease-presenilin pathway(P)(0.9985726)-FOXM1 transcription factor network(N)(0.853844)-GnRH signaling pathway(K)(0.9990922)-Integrins in angiogenesis(N)(0.993416)-LPA receptor mediated events(N)(0.9964178)-Leukocyte transendothelial migration(K)(0.9984582)-Pathways in cancer(K)(0.998071)-Plasma membrane estrogen receptor signaling(N)(0.9985858)-Proteogylcan syndecan-mediated signaling events(N)(0.998974)-Regulation of IGF Activity by IGFBP(R)(0.8769952)-amb2 Integrin signaling(N)(0.9977242) 331 RDH8 19p13.2 0 0 0 0 16 1 1130 0.6436 0 0.242424242424242 Metabolic pathways(K)(0.9979858) 332 CYP24A1 20q13.2 1 0 0 0 3 1 88 0.6436 0 0.0606060606060606 () 333 ARPC3 12q24.11 0 0 0 0 23 1 542 0.6436 0 0.348484848484849 Bacterial invasion of epithelial cells(K)(0.9972664)-Fc gamma R-mediated phagocytosis(K)(0.9962132)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.999276)-Integrin signalling pathway(P)(0.9985662)-Pathogenic Escherichia coli infection(K)(0.9966238)-Regulation of actin cytoskeleton(K)(0.9986798)-Shigellosis(K)(0.9975226) 334 TNFSF12 17p13.1 0 0 0 1 32 1 282 0.6436 0 0.5 Cytokine-cytokine receptor interaction(K)(0.9984022)-induction of apoptosis through dr3 and dr4/5 death receptors(B)(0.9980048) 335 NUTF2 16q22.1 0 0 0 0 17 1 12 0.6436 0 0.257575757575758 mechanism of protein import into the nucleus(B)(0.998505) 336 LAMA2 6q22.33 3 0 2 0 4 1 775 0.6436 0 0.136363636363636 Amoebiasis(K)(0.9991376)-Arrhythmogenic right ventricular cardiomyopathy (ARVC)(K)(0.8081826)-ECM-receptor interaction(K)(0.8323816)-Focal adhesion(K)(0.9972044)-Hypertrophic cardiomyopathy (HCM)(K)(0.9411938)-Integrin cell surface interactions(R)(0.9986)-Integrin signalling pathway(P)(0.9986696)-Pathways in cancer(K)(0.9995606)-a6b1 and a6b4 Integrin signaling(N)(0.986197)-agrin in postsynaptic differentiation(B)(0.9962266)-prion pathway(B)(0.825265) 337 BCL2 18q21.33 0 0 1 1 17 1 1450 0.6436 1 0.287878787878788 Amyotrophic lateral sclerosis (ALS)(K)(0.998212)-Apoptosis(K)(0.9894168)-Apoptosis(R)(0.9955038)-BMP receptor signaling(N)(0.9961474)-FAS signaling pathway (CD95)(N)(0.9856956)-Focal adhesion(K)(0.9992326)-Glypican pathway(N)(0.9933766)-IFN-gamma pathway(N)(0.9972192)-IL1-mediated signaling events(N)(0.9904292)-Neurotrophin signaling pathway(K)(0.9992554)-Oxidative stress response(P)(0.9960496)-Pathways in cancer(K)(0.9975676)-Prostate cancer(K)(0.991184)-Protein processing in endoplasmic reticulum(K)(0.9992968)-Retinoic acid receptors-mediated signaling(N)(0.9983344)-Signaling events mediated by Stem cell factor receptor (c-Kit)(N)(0.9933276)-Sphingosine 1-phosphate (S1P) pathway(N)(0.974651)-TNF receptor signaling pathway(N)(0.9954472)-prion pathway(B)(0.9888382)-telomeres telomerase cellular aging and immortality(B)(0.996108) 338 ACOT1 14q24.3 0 0 0 0 31 1 21 0.6436 0 0.46969696969697 Biosynthesis of unsaturated fatty acids(K)(0.9994264) 339 CYP2A6 19q13.2 1 0 1 0 8 1 1168 0.6436 0 0.151515151515152 Biological oxidations(R)(0.997719)-Drug metabolism - cytochrome P450(K)(0.965197)-Metabolic pathways(K)(0.9991306)-Retinol metabolism(K)(0.9560296) 340 GAS6 13q34 0 0 1 0 24 1 292 0.6436 0 0.378787878787879 Cell surface interactions at the vascular wall(R)(0.9989868)-Metabolism of proteins(R)(0.9964482) 341 HEXA 15q24.1 2 0 0 0 23 1 1228 0.6436 0 0.378787878787879 Amino sugar and nucleotide sugar metabolism(K)(0.9993368)-Lysosome(K)(0.999091)-Metabolic pathways(K)(0.9995644)-Other glycan degradation(K)(0.9976902) 342 SNUPN 15q24.2 0 0 0 1 23 1 49 0.6436 0 0.363636363636364 Metabolism of non-coding RNA(R)(0.9990662) 343 DLL1 6q27 0 0 0 0 26 1 120 0.6436 0 0.393939393939394 NOTCH(C)(0.998932)-Notch signaling pathway(K)(0.997803)-Presenilin action in Notch and Wnt signaling(N)(0.9752912) 344 PICALM 11q14.2 0 0 0 0 12 1 13 0.6436 1 0.181818181818182 () 345 GPHN 14q23.3 0 0 0 0 34 1 12 0.6436 1 0.515151515151515 gamma-aminobutyric acid receptor life cycle pathway(B)(0.9975338) 346 JAK3 19p13.11 0 0 2 0 18 1 719 0.6436 1 0.303030303030303 Chemokine signaling pathway(K)(0.9983586)-IFN-gamma pathway(N)(0.997565)-Interleukin signaling pathway(P)(0.9970194)-Jak-STAT signaling pathway(K)(0.9991582)-Primary immunodeficiency(K)(0.9974882)-role of erbb2 in signal transduction and oncology(B)(0.9959136) 347 LAMA1 18p11.31 1 0 3 0 13 1 1086 0.6436 0 0.242424242424242 Amoebiasis(K)(0.9976118)-ECM-receptor interaction(K)(0.9955702)-Focal adhesion(K)(0.9974574)-Glypican pathway(N)(0.9960378)-Integrin cell surface interactions(R)(0.9979374)-Integrin signalling pathway(P)(0.9962534)-Pathways in cancer(K)(0.9989968)-Proteogylcan syndecan-mediated signaling events(N)(0.9985732)-agrin in postsynaptic differentiation(B)(0.9953374)-prion pathway(B)(0.920178) 348 APBB1 11p15.4 2 0 0 1 25 1 313 0.6436 0 0.424242424242424 Alzheimer disease-amyloid secretase pathway(P)(0.9988222)-Alzheimer disease-presenilin pathway(P)(0.9987486)-Alzheimer's disease(K)(0.9990366) 349 B4GALT3 1q23.3 0 0 7 0 1 1 1130 0.6436 0 0.121212121212121 Metabolic pathways(K)(0.9992758) 350 MGAT4C 12q21.31 0 0 0 0 19 1 48 0.6436 0 0.287878787878788 N-Glycan biosynthesis(K)(0.998087) 351 OTUD5 23p11.23 0 0 0 7 23 1 71 0.6436 0 0.454545454545455 RIG-I-like receptor signaling pathway(K)(0.9996506) 352 BMP2 20p12.3 0 0 1 1 7 1 826 0.6436 0 0.136363636363636 BMP receptor signaling(N)(0.9964732)-Cytokine-cytokine receptor interaction(K)(0.996748)-Hedgehog signaling pathway(K)(0.9807782)-Pathways in cancer(K)(0.9983542)-TGF-beta signaling pathway(K)(0.9925768)-TGF-beta signaling pathway(P)(0.9963172) 353 SMAD6 15q22.31 0 0 0 0 27 1 515 0.6436 0 0.409090909090909 BMP receptor signaling(N)(0.99858)-Endocytosis(K)(0.998215)-Signaling by BMP(R)(0.9876044)-TGF-beta signaling pathway(K)(0.9982972)-TGF-beta signaling pathway(P)(0.9982264)-alk in cardiac myocytes(B)(0.9961338)-ctcf: first multivalent nuclear factor(B)(0.9947126) 354 GC 4q13.3 0 0 1 0 17 1 13 0.6436 0 0.272727272727273 Vitamin D metabolism and pathway(P)(0.981114) 355 TUB 11p15.4 0 0 0 1 24 1 11 0.6436 0 0.378787878787879 g-protein signaling through tubby proteins(B)(0.997406) 356 NFE2L2 2q31.2 0 0 0 0 11 1 184 0.6436 1 0.166666666666667 Protein processing in endoplasmic reticulum(K)(0.9995452)-oxidative stress induced gene expression via nrf2(B)(0.9958026) 357 CPT1B 22q13.33 0 0 0 1 19 1 290 0.6436 0 0.303030303030303 Activated AMPK stimulates fatty-acid oxidation in muscle(R)(0.9930664)-Adipocytokine signaling pathway(K)(0.9978772)-FOXA transcription factor networks(N)(0.986799)-Fatty acid metabolism(K)(0.9979978)-Metabolism of lipids and lipoproteins(R)(0.9986628)-PPAR signaling pathway(K)(0.9940234) 358 STX6 1q25.3 0 0 2 0 0 1 40 0.6436 0 0.0303030303030303 () 359 MTHFD1L 6q25.1 0 0 1 0 17 1 1124 0.6436 0 0.272727272727273 Metabolic pathways(K)(0.999482) 360 NR2E3 15q23 0 0 0 0 21 1 30 0.6436 0 0.318181818181818 NR transcription pathway(R)(0.9988088) 361 STXBP1 9q34.11 0 0 0 0 22 1 230 0.6436 0 0.333333333333333 Glucose Regulation of Insulin Secretion(R)(0.9974558)-Insulin Synthesis and Secretion(R)(0.9964712)-Synaptic Transmission(R)(0.9983294)-Synaptic_vesicle_trafficking(P)(0.9882976) 362 AOX1 2q33.1 1 0 0 0 11 1 1164 0.6436 0 0.181818181818182 Drug metabolism - cytochrome P450(K)(0.9806006)-Metabolic pathways(K)(0.9982484)-Nicotinate and nicotinamide metabolism(K)(0.8462602)-Tryptophan metabolism(K)(0.9965212) 363 GNGT1 7q21.3 0 0 0 0 3 1 863 0.6436 0 0.0454545454545455 Long-term potentiation(K)(0.9951566)-Olfactory Signaling Pathway(R)(0.9982582)-Thromboxane A2 receptor signaling(N)(0.8457868)-ion channels and their functional role in vascular endothelium(B)(0.9808348) 364 ATP2A3 17p13.2 0 0 0 1 37 1 414 0.6436 0 0.575757575757576 Alzheimer's disease(K)(0.9986588)-Calcium signaling pathway(K)(0.9986928)-Pancreatic secretion(K)(0.9992386)-nfat and hypertrophy of the heart (B)(0.9978744) 365 CENPJ 13q12.12 0 0 0 0 28 1 83 0.6436 0 0.424242424242424 G2/M Transition(R)(0.9993324) 366 DGKE 17q22 0 0 0 0 25 1 1164 0.6436 0 0.378787878787879 Glycerophospholipid metabolism(K)(0.9968402)-Metabolic pathways(K)(0.9986128)-Phosphatidylinositol signaling system(K)(0.9984588) 367 NEU3 11q13.4 0 0 0 0 11 1 51 0.6436 0 0.166666666666667 Other glycan degradation(K)(0.8441952)-Sphingolipid metabolism(K)(0.998694) 368 PDHX 11p13 0 0 3 0 15 1 1224 0.6436 0 0.272727272727273 Glucose Regulation of Insulin Secretion(R)(0.9974306)-Metabolic pathways(K)(0.9987336)-Metabolism of carbohydrates(R)(0.998715)-Regulation of pyruvate dehydrogenase complex (PDC)(R)(0.9962484) 369 RHEB 7q36.1 2 0 0 0 9 1 741 0.6436 0 0.166666666666667 Endothelins(N)(0.9988156)-Glypican pathway(N)(0.9090204)-IFN-gamma pathway(N)(0.9978482)-Insulin signaling pathway(K)(0.9984664)-TRAIL signaling pathway(N)(0.9788302)-mTOR signaling pathway(K)(0.9968032) 370 ALPL 1p36.12 0 0 1 0 18 1 1258 0.6436 0 0.287878787878788 Metabolic pathways(K)(0.9992416)-TNF alpha/NF-kB(C)(0.9979106)-regulators of bone mineralization(B)(0.9551362) 371 PSMB1 6q27 0 0 0 0 21 1 450 0.6436 0 0.318181818181818 Apoptosis(R)(0.998255)-Cell Cycle Checkpoints(R)(0.9970892)-G1/S Transition(R)(0.8036896)-Host Interactions of HIV factors(R)(0.9987996)-Metabolism of amino acids(R)(0.9983126)-Parkinson disease(P)(0.997191)-Proteasome(K)(0.9914072)-Signaling by Wnt(R)(0.9982014)-y branching of actin filaments(B)(0.996917) 372 LYPLA1 8q11.23 0 0 3 0 9 1 89 0.6436 0 0.181818181818182 Glycerophospholipid metabolism(K)(0.9969358)-Metabolism of nitric oxide(R)(0.8482644) 373 MYH9 22q12.3 1 0 0 0 16 1 404 0.6436 1 0.257575757575758 Nicotinic acetylcholine receptor signaling pathway(P)(0.997313)-Regulation of actin cytoskeleton(K)(0.9985748)-Tight junction(K)(0.999273)-Viral myocarditis(K)(0.9960392) 374 FGF16 23q21.1 0 0 1 5 20 1 684 0.6436 0 0.393939393939394 FGF signaling pathway(P)(0.9989596)-MAPK signaling pathway(K)(0.9992642)-Pathways in cancer(K)(0.998094)-Regulation of actin cytoskeleton(K)(0.9988316)-Signaling by FGFR(R)(0.9628992) 375 PRKCA 17q24.2 1 0 0 0 18 1 2422 0.6436 0 0.287878787878788 Aldosterone-regulated sodium reabsorption(K)(0.9915658)-Alpha6Beta4Integrin(C)(0.9613166)-Alzheimer disease-amyloid secretase pathway(P)(0.9945874)-Amoebiasis(K)(0.9918794)-Apoptosis signaling pathway(P)(0.984058)-BMP receptor signaling(N)(0.9896326)-Calcium signaling pathway(K)(0.997965)-EGF receptor signaling pathway(P)(0.8341884)-EGFR1(C)(0.9970482)-Endothelins(N)(0.9718864)-Fc gamma R-mediated phagocytosis(K)(0.9903308)-Focal adhesion(K)(0.9886426)-Formation of Platelet plug(R)(0.9973746)-Gap junction(K)(0.8425474)-Gastric acid secretion(K)(0.9926216)-GnRH signaling pathway(K)(0.8004898)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9961056)-IFN-gamma pathway(N)(0.9948536)-IL1-mediated signaling events(N)(0.9937986)-IL12-mediated signaling events(N)(0.9985906)-IL2-mediated signaling events(N)(0.9434698)-IL23-mediated signaling events(N)(0.9862708)-KitReceptor(C)(0.9586564)-Leukocyte transendothelial migration(K)(0.9962844)-Long-term depression(K)(0.9871222)-MAPK signaling pathway(K)(0.9969832)-Melanogenesis(K)(0.9301098)-Natural killer cell mediated cytotoxicity(K)(0.9988446)-Pancreatic secretion(K)(0.9968698)-Pathways in cancer(K)(0.997712)-Phosphatidylinositol signaling system(K)(0.995662)-Proteogylcan syndecan-mediated signaling events(N)(0.997318)-Retinoic acid receptors-mediated signaling(N)(0.989086)-Salivary secretion(K)(0.992901)-Signaling by Aurora kinases(N)(0.958581)-Signaling events mediated by VEGFR1 and VEGFR2(N)(0.9480736)-Signaling events regulated by Ret tyrosine kinase(N)(0.9737598)-TCR signaling in naive CD4+ T cells(N)(0.982925)-TNF receptor signaling pathway(N)(0.9721392)-Thromboxane A2 receptor signaling(N)(0.9697186)-Tight junction(K)(0.9989776)-Vascular smooth muscle contraction(K)(0.9923018)-Vibrio cholerae infection(K)(0.9957188)-Wnt signaling pathway(K)(0.9895304)-Wnt signaling pathway(P)(0.9992816)-Wnt(C)(0.992484)-adp-ribosylation factor(B)(0.8544184)-aspirin blocks signaling pathway involved in platelet activation(B)(0.9491126)-g-secretase mediated erbb4 signaling pathway(B)(0.8632372)-growth hormone signaling pathway(B)(0.8570546)-keratinocyte differentiation(B)(0.9361246)-oxidative stress induced gene expression via nrf2(B)(0.9839588)-p75(NTR)-mediated signaling(N)(0.9933662) 376 MED31 17p13.2 0 0 1 1 33 1 33 0.6436 0 0.53030303030303 Generic Transcription Pathway(R)(0.9990736) 377 IFI16 1q23.1 0 0 5 0 1 1 25 0.6436 0 0.0909090909090909 ID(C)(0.9958402) 378 SOS1 2p22.1 1 0 0 0 6 1 2152 0.6436 0 0.106060606060606 Chemokine signaling pathway(K)(0.99602)-EGF receptor signaling pathway(P)(0.844861)-Focal adhesion(K)(0.998732)-Formation of Platelet plug(R)(0.993586)-Gap junction(K)(0.99523)-Inflammation mediated by chemokine and cytokine signaling pathway(P)(0.9713862)-Insulin signaling pathway(K)(0.996634)-Integrin cell surface interactions(R)(0.9848256)-Jak-STAT signaling pathway(K)(0.9967678)-MAPK signaling pathway(K)(0.9979668)-Natural killer cell mediated cytotoxicity(K)(0.99618)-Pathways in cancer(K)(0.9925284)-Proteogylcan syndecan-mediated signaling events(N)(0.958073)-Signaling by Rho GTPases(R)(0.9967004)-Signaling events regulated by Ret tyrosine kinase(N)(0.808312)-Signalling by NGF(R)(0.9961702)-Sphingosine 1-phosphate (S1P) pathway(N)(0.9132768)-integrin signaling pathway(B)(0.8701658)-role of erbb2 in signal transduction and oncology(B)(0.8013658) 379 RET 10q11.21 0 0 0 0 11 1 704 0.6436 1 0.166666666666667 Endocytosis(K)(0.9976454)-Endothelin signaling pathway(P)(0.9980108)-Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9979088)-Pathways in cancer(K)(0.998401)-Signaling events regulated by Ret tyrosine kinase(N)(0.9984054) 380 CALM3 19q13.32 1 0 0 0 13 1 1205 0.6436 0 0.212121212121212 Alzheimer's disease(K)(0.9989446)-Calcium signaling pathway(K)(0.9996368)-Gastric acid secretion(K)(0.99198)-Glioma(K)(0.9567158)-GnRH signaling pathway(K)(0.9961216)-Insulin signaling pathway(K)(0.9975644)-Melanogenesis(K)(0.9963498)-Neurotrophin signaling pathway(K)(0.9994596)-Olfactory transduction(K)(0.9982952)-Oocyte meiosis(K)(0.9960298)-Phosphatidylinositol signaling system(K)(0.9950316)-Vascular smooth muscle contraction(K)(0.997075) 381 ACAT1 11q22.3 0 0 0 0 19 1 1292 0.6436 0 0.287878787878788 Fatty acid metabolism(K)(0.9423022)-Lysine degradation(K)(0.9942834)-Metabolic pathways(K)(0.9981076)-Metabolism of amino acids(R)(0.9969808)-Metabolism of lipids and lipoproteins(R)(0.9985338)-Pyruvate metabolism(K)(0.9946946)-Terpenoid backbone biosynthesis(K)(0.995787)-Tryptophan metabolism(K)(0.9965878) 382 RNASE3 14q11.2 0 0 0 0 24 1 31 0.6436 0 0.363636363636364 Asthma(K)(0.9981598) 383 MAN1B1 9q34.3 0 0 0 0 23 1 1281 0.6436 0 0.348484848484849 Metabolic pathways(K)(0.998453)-N-Glycan biosynthesis(K)(0.9977754)-Protein processing in endoplasmic reticulum(K)(0.9982994)-er associated degradation (erad) pathway(B)(0.996729) 384 TRPC6 11q22.1 1 0 0 0 15 1 206 0.6436 0 0.242424242424242 Endothelins(N)(0.9981416)-ion channels and their functional role in vascular endothelium(B)(0.9973226) 385 PLA2G1B 12q24.31 0 0 0 0 24 1 1644 0.6436 0 0.363636363636364 Arachidonic acid metabolism(K)(0.996506)-Fc epsilon RI signaling pathway(K)(0.9945126)-Glycerophospholipid metabolism(K)(0.9974516)-GnRH signaling pathway(K)(0.996658)-Long-term depression(K)(0.9936114)-MAPK signaling pathway(K)(0.9975258)-Metabolic pathways(K)(0.999329)-Pancreatic secretion(K)(0.99802)-VEGF signaling pathway(K)(0.9967882)-Vascular smooth muscle contraction(K)(0.9953486)-eicosanoid metabolism(B)(0.9098588)-p38 mapk signaling pathway(B)(0.992614) 386 HMBS 11q23.3 0 0 0 0 19 1 1134 0.6436 0 0.287878787878788 Metabolic pathways(K)(0.997793)-Porphyrin and chlorophyll metabolism(K)(0.997272) 387 SLC25A18 22q11.21 1 0 0 0 22 1 11 0.6436 0 0.348484848484849 visual signal transduction(B)(0.9987818) 388 SPIRE1 18p11.21 2 0 2 0 13 1 25 0.6436 0 0.257575757575758 Dorso-ventral axis formation(K)(0.9985126) 389 TARBP2 12q13.13 0 0 0 0 25 1 18 0.6436 0 0.378787878787879 Regulatory RNA pathways(R)(0.9986602) 390 BRCA1 17q21.31 0 0 0 0 34 1 535 0.6436 1 0.515151515151515 Androgen-mediated signaling(N)(0.98378)-AndrogenReceptor(C)(0.9969284)-BARD1 signaling events(N)(0.9919204)-DNA Repair(R)(0.9979846)-FOXA transcription factor networks(N)(0.9839954)-Signaling by Aurora kinases(N)(0.9802748)-Ubiquitin mediated proteolysis(K)(0.9987244)-atm signaling pathway(B)(0.9792792)-cell cycle: g2/m checkpoint(B)(0.9950936)-role of brca1 brca2 and atr in cancer susceptibility(B)(0.9895238) 391 TNNT3 11p15.5 0 0 0 1 29 1 31 0.6436 0 0.454545454545455 Muscle contraction(R)(0.9989594) 392 CA12 15q22.2 0 0 0 1 25 1 23 0.6436 0 0.393939393939394 Nitrogen metabolism(K)(0.9983172) 393 MAN2B2 4p16.1 0 0 2 1 32 1 16 0.6436 0 0.53030303030303 Other glycan degradation(K)(0.9970278) 394 MLLT4 6q27 1 0 0 0 21 1 413 0.6436 1 0.333333333333333 Adherens junction(K)(0.9959694)-Alzheimer disease-presenilin pathway(P)(0.999283)-Leukocyte transendothelial migration(K)(0.9953092)-Nectin adhesion pathway(N)(0.9894368)-Tight junction(K)(0.9965414) 395 HAO1 20p12.3 0 0 1 1 6 1 1167 0.6436 0 0.121212121212121 Metabolic pathways(K)(0.998854)-Peroxisome(K)(0.9967972) 396 NUP93 16q13 0 0 0 1 21 1 429 0.6436 0 0.333333333333333 HIV Life Cycle(R)(0.9924878)-Host Interactions of HIV factors(R)(0.9969376)-Influenza Life Cycle(R)(0.9971762)-Metabolism of carbohydrates(R)(0.998409)-Metabolism of non-coding RNA(R)(0.994256)-Transport of Mature Transcript to Cytoplasm(R)(0.9892604) 397 GRM6 5q35.3 0 0 0 2 31 1 410 0.6436 0 0.5 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway(P)(0.9978356)-Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9971382)-Metabotropic glutamate receptor group III pathway(P)(0.8975644)-Neuroactive ligand-receptor interaction(K)(0.9985376) 398 POLR1A 2p11.2 2 0 0 0 7 1 1428 0.6436 0 0.136363636363636 Metabolic pathways(K)(0.9997408)-Purine metabolism(K)(0.995544)-TNF alpha/NF-kB(C)(0.9970976)-Transcription(R)(0.999626) 399 ACE2 23p22.2 0 0 0 8 22 1 17 0.6436 0 0.454545454545455 Renin-angiotensin system(K)(0.9994838) 400 EPRS 1q41 0 0 3 0 0 1 1171 0.6436 0 0.0454545454545455 Aminoacyl-tRNA biosynthesis(K)(0.9979322)-Metabolic pathways(K)(0.9984724) 401 HSD11B2 16q22.1 0 0 0 0 18 1 1172 0.6436 0 0.272727272727273 Aldosterone-regulated sodium reabsorption(K)(0.9986534)-Metabolic pathways(K)(0.9989082)-Steroid hormone biosynthesis(K)(0.9979592) 402 CARD8 19q13.32 0 0 0 0 16 1 62 0.6436 0 0.242424242424242 NOD-like receptor signaling pathway(K)(0.9992086) 403 GATM 15q21.1 0 0 0 3 35 1 1126 0.6436 0 0.575757575757576 Glycine, serine and threonine metabolism(K)(0.9987648)-Metabolic pathways(K)(0.9993364) 404 DMGDH 5q14.1 1 0 0 3 35 1 1125 0.6436 0 0.590909090909091 Glycine, serine and threonine metabolism(K)(0.9982752)-Metabolic pathways(K)(0.99866) 405 SNRPB 20p13 0 0 1 1 8 1 502 0.6436 0 0.151515151515152 Formation and Maturation of mRNA Transcript(R)(0.9911744)-Influenza Life Cycle(R)(0.998505)-Metabolism of non-coding RNA(R)(0.9936972)-Spliceosome(K)(0.997632)-Systemic lupus erythematosus(K)(0.9968132) 406 POLR2F 22q13.1 0 0 1 0 16 1 1635 0.6436 0 0.257575757575758 DNA Repair(R)(0.9987226)-Formation and Maturation of mRNA Transcript(R)(0.9964044)-Huntington's disease(K)(0.9988916)-Influenza Life Cycle(R)(0.9989816)-Metabolic pathways(K)(0.998048)-Purine metabolism(K)(0.9982476)-Pyrimidine metabolism(K)(0.9893826)-Regulatory RNA pathways(R)(0.989308)-Transcription(R)(0.996543)-mRNA Processing(R)(0.8739958) 407 VTI1A 10q25.2 1 0 0 1 19 1 36 0.6436 1 0.318181818181818 SNARE interactions in vesicular transport(K)(0.9990172) 408 NEIL3 4q34.3 0 0 0 2 28 1 34 0.6436 0 0.454545454545455 Base excision repair(K)(0.9989764) 409 FBXL3 13q22.3 0 0 0 2 25 1 223 0.6436 0 0.409090909090909 Circadian rhythm - mammal(K)(0.9985266)-Metabolism of proteins(R)(0.9989616) 410 GSR 8p12 1 0 0 2 29 1 102 0.6436 0 0.484848484848485 Glutathione metabolism(K)(0.9996314)-Metablism of nucleotides(R)(0.9985112) 411 PGM1 1p31.3 2 0 0 0 8 1 1322 0.6436 0 0.151515151515152 Amino sugar and nucleotide sugar metabolism(K)(0.9932804)-Hypoxic and oxygen homeostasis regulation of HIF-1-alpha(N)(0.995737)-Metabolic pathways(K)(0.999222)-Metabolism of carbohydrates(R)(0.9983312)-Purine metabolism(K)(0.9988358) 412 AARS 16q22.1 0 0 0 0 16 1 44 0.6436 0 0.242424242424242 Aminoacyl-tRNA biosynthesis(K)(0.9981748) 413 SERPINF2 17p13.3 0 0 0 1 38 1 169 0.6436 0 0.590909090909091 Complement and coagulation cascades(K)(0.999234)-Formation of Platelet plug(R)(0.9989646) 414 SRR 17p13.3 0 0 0 1 37 1 32 0.6436 0 0.575757575757576 Glycine, serine and threonine metabolism(K)(0.9977576) 415 RAP1GAP 1p36.12 0 0 1 0 18 1 113 0.6436 0 0.287878787878788 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway(P)(0.9984916) 416 MYH13 17p13.1 0 0 0 1 43 1 489 0.6436 0 0.666666666666667 Nicotinic acetylcholine receptor signaling pathway(P)(0.9971522)-Tight junction(K)(0.9984262)-Viral myocarditis(K)(0.997641)-Wnt signaling pathway(P)(0.9982984) 417 KLC3 19q13.32 0 0 0 0 12 1 58 0.6436 0 0.181818181818182 Alzheimer disease-amyloid secretase pathway(P)(0.9982272) 418 HS2ST1 1p22.3 0 0 1 0 9 1 26 0.6436 0 0.151515151515152 Glycosaminoglycan biosynthesis - heparan sulfate(K)(0.9988894) 419 CHRNA7 15q13.3 0 0 0 3 35 1 436 0.6436 0 0.575757575757576 Alzheimer disease-amyloid secretase pathway(P)(0.9969354)-Calcium signaling pathway(K)(0.9985344)-Neuroactive ligand-receptor interaction(K)(0.998468) 420 DARC 1q23.2 0 0 5 0 1 1 232 0.6436 0 0.0909090909090909 Class A/1 (Rhodopsin-like receptors)(R)(0.9979412)-Malaria(K)(0.9977238) 421 LRP2 2q31.1 4 0 0 0 10 1 194 0.6436 0 0.212121212121212 Alzheimer disease-presenilin pathway(P)(0.9979298)-Signaling events mediated by the Hedgehog family(N)(0.9640252) 422 COL6A2 21q22.3 0 0 0 0 20 1 330 0.6436 0 0.303030303030303 ECM-receptor interaction(K)(0.9981058)-Focal adhesion(K)(0.9987218)-Integrin signalling pathway(P)(0.9974128)-Signaling by PDGF(R)(0.9971984) 423 ACSL4 23q22.3 1 0 0 6 20 1 1259 0.6436 0 0.409090909090909 Adipocytokine signaling pathway(K)(0.99872)-Metabolic pathways(K)(0.998796)-PPAR signaling pathway(K)(0.9985906)-Peroxisome(K)(0.9975954) 424 GEMIN6 2p22.1 0 0 0 0 6 1 49 0.6436 0 0.0909090909090909 Metabolism of non-coding RNA(R)(0.9983598) 425 ERCC8 5q12.1 0 0 0 5 32 1 225 0.6436 0 0.560606060606061 DNA Repair(R)(0.9981736)-Nucleotide excision repair(K)(0.997468)-Ubiquitin mediated proteolysis(K)(0.9983766) 426 MINPP1 10q23.2 0 0 0 2 18 1 57 0.6436 0 0.303030303030303 Inositol phosphate metabolism(K)(0.9988464) 427 PPP3R2 9q31.1 1 0 0 0 17 1 1217 0.6436 0 0.272727272727273 Alzheimer's disease(K)(0.9965476)-Amyotrophic lateral sclerosis (ALS)(K)(0.9949266)-Apoptosis(K)(0.9990134)-Axon guidance(K)(0.9980102)-B cell receptor signaling pathway(K)(0.9958416)-Calcium signaling pathway(K)(0.9972144)-Long-term potentiation(K)(0.9457268)-MAPK signaling pathway(K)(0.998202)-Natural killer cell mediated cytotoxicity(K)(0.9979172)-Oocyte meiosis(K)(0.9979602)-T cell receptor signaling pathway(K)(0.9947452)-Wnt signaling pathway(K)(0.9962402)-Wnt signaling pathway(P)(0.9987522) 428 HSD17B1 17q21.31 0 0 0 0 33 1 1132 0.6436 0 0.5 Metabolic pathways(K)(0.9988336)-Steroid hormone biosynthesis(K)(0.997705) 429 ABLIM2 4p16.1 0 0 1 1 34 1 129 0.6436 0 0.545454545454545 Axon guidance(K)(0.9983434) 430 CENPH 5q13.2 0 0 0 3 31 1 96 0.6436 0 0.515151515151515 M Phase(R)(0.9981642)