gb-2003-4-3-312 GBJ Paper report <p>Articles selected by Faculty <it>of</it><b> 1000</b>: p53 gene silencing; duplications in the <it>Arabidopsis</it> genome; RNA interference and disease protection; arraying environmental gene diversity; predicting RNA folding patterns.</p> Genome Biology 1465-6906 2003 4 3 312 http://genomebiology.com/2003/4/3/312/ 10.1186/gb-2003-4-3-312 26 2 2003 2003 BioMed Central Ltd

p53 gene silencing; duplications in the Arabidopsis genome; RNA interference and disease protection; arraying environmental gene diversity; predicting RNA folding patterns.

A selection of evaluations from Faculty of 1000 covering p53 gene silencing, Arabidopsis genome duplications, RNA interference and disease protection, environmental gene diversity and predicting RNA folding patterns.

Summary

A selection of evaluations from Faculty of 1000 covering p53 gene silencing, Arabidopsis genome duplications, RNA interference and disease protection, environmental gene diversity and predicting RNA folding patterns.

 Genome studies Medicine Genetics Plant biology Bioinformatics

p53 gene silencing

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Hemann MT, Fridman JS, Zilfou JT, Hernando E, Paddison PJ, Cordon-Cardo C, Hannon GJ, Lowe SW. Nat Genet 2003, doi:10.1038/ng1091

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Hemann

Duplications in the Arabidopsis genome

A recent polyploidy superimposed on older large-scale duplications in the Arabidopsis genome. Blanc G, Hokamp K, Wolfe KH. Genome Res 2003, 13:137-144.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Blanc

RNA interference and disease protection

RNA interference targeting Fas protects mice from fulminant hepatitis. Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman J. Nat Med 2003, doi:10.1038/nm828

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Song

Arraying environmental gene diversity

Oligonucleotide microarray for the study of functional gene diversity in the nitrogen cycle in the environment. Taroncher-Oldenburg G, Griner EM, Francis CA, Ward BB. Appl Environ Microbiol 2003, 69:1159-1171.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Taroncher

Predicting RNA folding patterns

Discovering well-ordered folding patterns in nucleotide sequences. Le SY, Chen JH, Konings D, Maizel JV. Bioinformatics 2003 19:354-361.

For the Faculty of 1000 evaluation of this article please see: http://genomebiology.com/reports/F1000/gb-2003-4-3-312.asp#Le