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<art>
   <ui>gb-spotlight-20030314-01</ui>
   <ji>GBJ</ji>
   <fm>
      <dochead>Research news</dochead>
      <bibl>
         <title>
            <p>Shaping a snapdragon</p>
         </title>
         <aug>
            <au id="A1">
               <snm>Weitzman</snm>
               <mi>B</mi>
               <fnm>Jonathan</fnm>
               <email>jonathanweitzman@hotmail.com</email>
            </au>
         </aug>
         <source>Genome Biology</source>
         <issn>1465-6906</issn>
         <pubdate>2003</pubdate>
         <volume>4</volume>
         <fpage>spotlight-20030314-01</fpage>
         <xrefbib>
            <pubid idtype="doi">10.1186/gb-spotlight-20030314-01</pubid>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>14</day>
               <month>3</month>
               <year>2003</year>
            </date>
         </pub>
      </history>
      <cpyrt>
         <year>2003</year>
         <collab>BioMed Central Ltd</collab>
      </cpyrt>
      <shortabs>
         <p>Clonal analysis has been used to explore the role of cell growth in petal shape formation.</p>
      </shortabs>
   </fm>
   <meta>
      <classifications>
         <classification type="news" subtype="status">Live</classification>
      </classifications>
   </meta>
   <bdy>
      <sec>
         <st>
            <p/>
         </st>
         <p>The rate, orientation and direction of cell growth and division determine the shape that a given tissue will adopt. In the March 13 <abbr bid="B1"><it>Nature</it></abbr> Anne-Gaelle Rolland-Lagan and colleagues at the <abbr bid="B2">John Innes Centre</abbr>, Norwich, UK, describe using a clonal analysis to investigate the role of cell growth in the development of asymmetric petals in the plant <abbr bid="B3"><it>Antirrhinum</it></abbr> (snapdragon) (<it>Nature</it> 2003, <b>422:</b>161-163). Measurements of the spatiotemporal changes in cell proliferation and anisotropy (the preferential direction of growth) were combined with computational modelling. They found that the direction of growth rather than regional differences in growth rate (cell doubling time) dictated petal asymmetry. In an accompanying review, Claude Desplan and Thomas Lecuit draw striking parallels with analysis of wing formation in <it>Drosophila</it> and comment that the snapdragon study "provide[s] a simple, quantitative, dynamic model in which just a few parameters are sufficient to explain the final shape of the tissue."</p>
      </sec>
   </bdy>
   <bm>
      <refgrp>
         <bibl id="B1">
            <url>http://www.nature.com</url>
            <note>
               <it>Nature</it>
            </note>
         </bibl>
         <bibl id="B2">
            <url>http://www.jic.bbsrc.ac.uk/</url>
            <note>John Innes Centre </note>
         </bibl>
         <bibl id="B3">
            <note>Control of organ asymmetry in flowers of <it>Antirrhinum</it>.</note>
            <xrefbib>
               <pubid idtype="pmpid" link="fulltext">10571179</pubid>
            </xrefbib>
         </bibl>
      </refgrp>
   </bm>
</art>
