Genome Biology
Volume 9
Issue 4 |
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ReviewThe AAA+ superfamily of functionally diverse proteinsJamie Snider* , Guillaume Thibault* and Walid A Houry  Department of Biochemistry, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada  author email corresponding author email* Contributed equally
Genome Biology 2008,
9:216doi:10.1186/gb-2008-9-4-216
Subject areas: Biochemistry and structural biology, Cell biology Abstract
The AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes, attaining this functional diversity through additions of structural motifs and modifications to the core AAA+ module. | 
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