MAPPFinder 1.0 Results for Local MAPPs File: C:\MAPPFinder Additional Files\FVBN Developmental Data from CardioGenomics.gex Statistics: 2141 Genes met the [Embryo fold] > 1.2 AND[embryo permute p] < 0.05 criteria. 1904 Genes did not link to a MAPP. 237 genes were used to calculate the results shown below. The z score is based on an N of 951 and a R of 237 distinct genes. MAPPName Number Changed Number Measured Number on MAPP Percent Changed Percent Present z Score Mm_Ribosomal Proteins 32 45 69 71.1 65.2 7.109 Mm_Gene Trap Resource_2-04-02_Named Genes 82 182 358 45.1 50.8 6.09 Mm_Gene Trap Resource_2-04-02_Named Genes 2 19 46 89 41.3 51.7 2.549 Mm_Cell cycle 8 15 18 53.3 83.3 2.538 Mm_Cholesterol Biosynthesis 5 8 11 62.5 72.7 2.454 Mm_Translation Factors 10 24 32 41.7 75 1.889 Mm_C-21 Steroid Hormone Metabolism 1 1 2 100 50 1.736 Mm_Glycogen Metabolism 3 6 14 50 42.9 1.419 Mm_Apoptosis 12 39 43 30.8 90.7 0.839 Mm_tRNA Synthetases 1 2 20 50 10 0.82 Mm_Catacholamine Biosynthesis 1 2 4 50 50 0.82 Mm_Pentose Phosphate Pathway 2 5 6 40 83.3 0.779 Mm_Sarcomere 11 38 50 28.9 76 0.57 Mm_Fatty Acid Synthesis 2 6 11 33.3 54.5 0.476 Mm_Proteasome Degradation 7 25 41 28 61 0.354 Mm_Androgen and Estrogen Metabolism 1 3 7 33.3 42.9 0.337 Mm_GPCRs, Class B Secretin-like 3 11 18 27.3 61.1 0.18 Mm_Steroid Biosynthesis 3 12 14 25 85.7 0.006 Mm_Glucocorticoid & Mineralocorticoid Metabolism 2 9 13 22.2 69.2 -0.187 Mm_G13 Signaling Pathway 6 27 36 22.2 75 -0.323 Mm_Acetylcholine Synthesis 1 6 7 16.7 85.7 -0.467 Mm_TGF Beta Signaling Pathway 6 30 48 20 62.5 -0.62 Mm_Fatty Acid Degradation 2 13 15 15.4 86.7 -0.793 Mm_MAPK Cascade 3 20 26 15 76.9 -1.022 Mm_Wnt Signaling 9 49 62 18.4 79 -1.052 Mm_Complement Activation, Classical 1 10 12 10 83.3 -1.089 Mm_G Protein Signaling 8 45 69 17.8 65.2 -1.099 Mm_Blood Clotting Cascade 2 16 21 12.5 76.2 -1.146 Mm_Eicosanoid Synthesis 2 16 19 12.5 84.2 -1.146 Mm_Orphan GPCRs 2 18 22 11.1 81.8 -1.351 Mm_Glycolysis and Gluconeogenesis 3 25 36 12 69.4 -1.487 Mm_Electron Transport Chain 2 20 58 10 34.5 -1.538 Mm_Nuclear Receptors 4 35 39 11.4 89.7 -1.835 Mm_Inflammatory Response Pathway 4 36 41 11.1 87.8 -1.904 Mm_GPCRs, Other 1 19 240 5.3 7.9 -1.975 Mm_Monoamine GPCRs 1 23 33 4.3 69.7 -2.272 Mm_Peptide GPCRs 1 54 68 1.9 79.4 -3.883 Mm_GPCRs, Class A Rhodopsin-like 3 130 252 2.3 51.6 -5.831