gb-2004-5-2-p6 GBJ Deposited research article <p>Prediction for Target Sites of Small Interfering RNA Duplexes in SARS Coronavirus</p> Ji Fengmin Luo Liaofu lfluo@mail.imu.edu.cn

Institute for Biological Science and Technology,Faculty of Sciences, North Jiaotong University, Beijing, 100044 China

Laboratory of Theoretical Biophysics, Faculty of Sciences and Technology, Inner Mongolia University, Hohhot, 010021 China

Center for Theoretical Biology, Peking University, Beijing, 100871 China

 Genome Biology 1465-6906 2004 5 2 P6 http://genomebiology.com/2004/5/2/P6 This is the first version of this article to be made available publicly. 10.1186/gb-2004-5-2-p6 14 1 2004 16 1 2004 2004 BioMed Central Ltd

RNA interference is used for SARS-related pharmaceutical research and development. Using a bioinformatic method twenty seven, 21-25-base sequence segments in the SARS-coronavirus genome are predicted as the optimal target sites of small interfering RNA duplexes.

Abstract

RNA interference is used for SARS-related pharmaceutical research and development. Following bioinformatic method twenty seven 21~25 base-long sequence segments in SARS-CoV genome are predicted as the optimal target sites of small interfering RNA duplexes.

 Virology Bioinformatics Molecular biology Genome studies