Genome Biology aims to provide the best possible service to authors and readers of primary research articles. The method section publishes peer-reviewed methods in all areas of molecular, cellular, organismal and population biology that are informed by genomics. All method articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how methods are published in Genome Biology, and for instructions for authors,see 'about refereed research'.

Method    

(16 June 2009)

The mean expression value: a new method for accurate and reliable normalization of microRNA expression data from RT-qPCR experiments.

Method    

(2 June 2009)

A novel method for closing non-structural gaps in the human genome assembly using 454 sequencing is presented here.

Method    

(19 April 2009)

The genome-scale data collected by the FANTOM4 collaborative research project are presented as an integrated web resource.

Method    

(24 April 2009)

A method is proposed that finds enriched pathways relevant to a studied condition, using molecular and network data.

Method    

(18 March 2009)

A computational method is presented for genome-wide mapping of splicing factor binding sites that considers both the genomic environment and evolutionary conservation.

Method    

(10 March 2009)

A new machine learning-based method is presented here for the identification of metabolic pathways related to specific phenotypes in multiple microbial genomes.

Method    

(6 March 2009)

DISTILLER, a data integration framework for the inference of transcriptional module networks, is presented and used to investigate the condition dependency and modularity in Escherichia coli networks.

Method    

(10 February 2009)

A new method for rapid genome-wide ChIP-chip from as few as 1,000 cells.