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	1.	Research A blood based 12-miRNA signature of Alzheimer disease patients Petra Leidinger, Christina Backes, Stephanie Deutscher, Katja Schmitt, Sabine C Muller, Karen Frese, Jan Haas, Klemens Ruprecht, Friedemann Paul, Cord Stahler, Christoph JG Lang, Benjamin Meder, Tamas Bartfai, Eckart Meese, Andreas Keller Genome Biology 2013, 14:R78 (29 July 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A 12-miRNA signature in blood samples can be used to detect Alzheimer’s disease and other neurological disorders
	2.	Software REAPR: a universal tool for genome assembly evaluation Martin Hunt, Taisei Kikuchi, Mandy Sanders, Chris Newbold, Matthew Berriman, Thomas D Otto Genome Biology 2013, 14:R47 (27 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A new user-friendly software tool for genome assembly evaluation
	3.	Correspondence The advantages of SMRT sequencing Richard J Roberts, Mauricio O Carneiro, Michael C Schatz Genome Biology 2013, 14:405 (3 July 2013) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Rich Roberts, Mauricio Carneiro and Michael Schatz argue for a greater uptake of the impressive PacBio SMRT sequencing platform
	4.	Poster presentation CIPRO 2.5: Ciona intestinalis Protein Database - a unique integrated repository of large-scale omics data, bioinformatic analyses, and curated annotation, with ability for user rating and comments Toshinori Endo, Keisuke Ueno, Kouki Yonezawa, Katsuhiko Mineta, Kohji Hotta, Yutaka Satou, Lixy Yamada, Michio Ogasawara, Hiroki Takahashi, Ayako Nakajima, Mia Nakachi, Mamoru Nomura, Junko Yaguchi, Alu Konno, Yasunori Sasakura, Akiyasu C Yoshizawa, Hisaaki Taniguchi, Chisato Yamasaki, Miho Sera, Tadashi Imanishi, Kazuo Inaba Genome Biology 2010, 11(Suppl 1):P11 (11 October 2010) Full text \| PDF
	5.	Research VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer Georges St Laurent, Dmitry Shtokalo, Biao Dong, Michael R Tackett, Xiaoxuan Fan, Sandra Lazorthes, Estelle Nicolas, Nianli Sang, Timothy J Triche, Timothy A McCaffrey, Weidong Xiao, Philipp Kapranov Genome Biology 2013, 14:R73 (22 July 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary The expression of vlincRNAs from retroviral promoters is correlated with pluripotency and malignancy
	6.	Meeting report Non-classical immunology Rachel L Allen Genome Biology 2001, 2:reports4004-reports4004.4 (7 February 2001) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A report on the British Society for Immunology Annual Congress, Harrogate, UK, 5-8 December 2000.
	7.	Paper report Articles selected by Faculty of 1000: single-cell neuronal expression analysis; array analysis of chick hair cells; coiled-coil protein arrays; high-throughput identification of plasmodesmata-interacting proteins; multicompenent therapeutics Genome Biology 2003, 4:334 (18 July 2003) Abstract \| Full text \| Editor’s summary A selection of evaluations from Faculty of 1000 covering single-cell neuronal expression analysis, array analysis of chick hair cells, coiled-coil protein arrays, high-throughput identification of plasmodesmata-interacting proteins and multicompenent therapeutics.
	8.	Protein family review The integrins Yoshikazu Takada, Xiaojing Ye, Scott Simon Genome Biology 2007, 8:215 (1 June 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An overview of a family of cell-surface adhesion and signaling receptors that mediate cell-cell adhesion and cell-extracellular matrix adhesion.
	9.	Protein family review The cullin protein family Antonio Sarikas, Thomas Hartmann, Zhen-Qiang Pan Genome Biology 2011, 12:220 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| 1 comment \| Editor’s summary Cullin proteins are molecular scaffolds involved in the posttranslational modification of cellular proteins by ubiquitin.
	10.	Research Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast Daniel H Lackner, Michael W Schmidt, Shuangding Wu, Dieter A Wolf, Jürg Bähler Genome Biology 2012, 13:R25 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Changes in transcription and translation are measured in fission yeast exposed to different stresses to elucidate layers of gene expression control
	11.	Software MetAMOS: a modular and open source metagenomic assembly and analysis pipeline Todd J Treangen, Sergey Koren, Daniel D Sommer, Bo Liu, Irina Astrovskaya, Brian Ondov, Aaron E Darling, Adam M Phillippy, Mihai Pop Genome Biology 2013, 14:R2 (15 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A modular, metagenomic analysis and assembly pipeline that inputs next-generation sequencing reads to generate genomic scaffolds and open reading frames
	12.	Research Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes James P Reddington, Sara M Perricone, Colm E Nestor, Judith Reichmann, Neil A Youngson, Masako Suzuki, Diana Reinhardt, Donncha S Dunican, James G Prendergast, Heidi Mjoseng, Bernard H Ramsahoye, Emma Whitelaw, John M Greally, Ian R Adams, Wendy A Bickmore, Richard R Meehan Genome Biology 2013, 14:R25 (25 March 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary An intact DNA methylome is required for appropriate Polycomb-mediated gene repression, as revealed by H3K4me3 and PRC2 mapping in hypomethylated cells
	13.	Research Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors Pedro Casado, Maria P Alcolea, Francesco Iorio, Juan-Carlos Rodríguez-Prados, Bart Vanhaesebroeck, Julio Saez-Rodriguez, Simon Joel, Pedro R Cutillas Genome Biology 2013, 14:R37 (29 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A phosphoproteomic approach helps to distinguish between different types of blood cancers and gauges their sensitivity to kinase inhibitors
	14.	Research Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance David Martino, Yuk Loke, Lavinia Gordon, Miina Ollikainen, Mark N Cruickshank, Richard Saffery, Jeffrey M Craig Genome Biology 2013, 14:R42 (22 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A longitudinal study of DNA methylation in twins at birth and 18 months finds that some loci drift in methylation status
	15.	Review Biofuel and energy crops: high-yield Saccharinae take center stage in the post-genomics era Savio de Siqueira Ferreira, Milton Nishiyama, Andrew H Paterson, Glaucia Souza Genome Biology 2013, 14:210 (27 June 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A Review of developments in our ability to improve desirable traits in biofuel and energy crops
	16.	Research The plasticity of the grapevine berry transcriptome Silvia Dal Santo, Giovanni Tornielli, Sara Zenoni, Marianna Fasoli, Lorenzo Farina, Andrea Anesi, Flavia Guzzo, Massimo Delledonne, Mario Pezzotti Genome Biology 2013, 14:r54 (7 June 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A transcriptomic and metabolomic analysis of the plasticity of grapevine berry gene expression in response to development and the environment
	17.	Research Comprehensive genotyping of the USA national maize inbred seed bank Maria C Romay, Mark J Millard, Jeffrey C Glaubitz, Jason A Peiffer, Kelly L Swarts, Terry M Casstevens, Robert J Elshire, Charlotte B Acharya, Sharon E Mitchell, Sherry A Flint-Garcia, Michael D McMullen, James B Holland, Edward S Buckler, Candice A Gardner Genome Biology 2013, 14:R55 (11 June 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Genotyping-by-Sequencing analysis of maize inbred accessions, identifying candidate genes for kernel color, sweet corn, and flowering time
	18.	Method User guide for mapping-by-sequencing in Arabidopsis Geo James, Vipul Patel, Karl JV Nordström, Jonas R Klasen, Patrice A Salomé, Detlef Weigel, Korbinian Schneeberger Genome Biology 2013, 14:R61 (17 June 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Method for mapping-by-sequencing in Arabidopsis, using the Pop-seq software, and application to barley and rice as well
	19.	Research Separating homeologs by phasing in the tetraploid wheat transcriptome Ksenia V Krasileva, Vince Buffalo, Paul Bailey, Stephen Pearce, Sarah Ayling, Facundo Tabbita, Marcelo Soria, Shichen Wang, Iwgs Consortium, Eduard Akhunov, Cristobal Uauy, Jorge Dubcovsky Genome Biology 2013, 14:R66 (25 June 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary A novel transcriptome assembly pipeline that separates merged homeologs allows assembly of the tetraploid wheat transcriptome
	20.	Research A compact, in vivo screen of all 6-mers reveals drivers of tissue-specific expression and guides synthetic regulatory element design Robin P Smith, Samantha J Riesenfeld, Alisha K Holloway, Qiang Li, Karl K Murphy, Natalie M Feliciano, Lorenzo Orecchia, Nir Oksenberg, Katherine S Pollard, Nadav Ahituv Genome Biology 2013, 14:R72 (18 July 2013) Abstract \| Provisional PDF \| PubMed \| 1 comment \| Editor’s summary All possible 6-mers are incorporated into a compact set of 15-mer synthetic enhancer sequences, which are then screened in zebrafish embryos
	21.	Method GLiMMPS: Robust statistical model for regulatory variation of alternative splicing using RNA-Seq data Keyan Zhao, Zhi-xiang Lu, Juw Won Park, Qing Zhou, Yi Xing Genome Biology 2013, 14:R74 (22 July 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary GLiMMPS is a method for detecting QTLs associated with alternative splicing