Genome Biology publishes opinion pieces on a broad range of topics, including political, scientific, and medical issues relating to genomic, post-genomic and genome-scale analyses. Readers will be encouraged to participate in discussions and to comment on articles via the website. Most opinion articles will be commissioned, so as to ensure a comprehensive and systematic coverage, but you are encouraged to send suggestions to the editors.

Opinion   

(2 November 2007)

Better methods of statistical analysis could make large-scale protein-interaction data more useful.

Opinion    

(1 February 2007)

Genome annotation currently tends to represent a static snapshot. Routine re-annotation, perhaps using wiki software, would help.

Opinion    

(1 December 2006)

How can protein-interaction networks can be made more complete?

Opinion    

(1 November 2006)

As lateral gene transfer among prokaryotes and endosymbiotic gene transfer (from organelles) among eukaryotes are fundamentally not tree-like in nature, biologists need to depart from the notion that all genomes are related by a single bifurcating tree.

Opinion    

(29 September 2006)

Do we need to describe bacteria as species, and if so, can we?

Opinion    

(30 August 2006)

Various practical challenges involved in controlling living organisms must be surmounted if synthetic biology is to be productive.