Genome Biology aims to provide review material that readers need in order to assess and evaluate progress in genomic and post-genomic research. Protein family reviews aim to provide a standardized set of information about families of structurally and functionally related proteins. Each protein family review includes information on gene and protein structure, evolution, localization and function, and is intended as a quick reference source for readers unfamiliar with the family. Protein family reviews are usually commissioned, with the editors aiming to ensure coverage of all relevant areas of biology and genomics but suggestions of protein family reviews are welcome.

Protein family review   

(29 December 2009)

A review of the PIN auxin-efflux transporters, which have important roles in plant development.

Protein family review   

(29 December 2009)

The plant-specific WOX family of homeobox proteins have key functions in plant development.

Protein family review   

(27 October 2009)

The SR proteins are not only involved in pre-mRNA splicing but in mRNA export and the initiation of translation.

Protein family review   

(29 September 2009)

The netrins are a family of extracellular proteins that direct cell and axon migration during embryogenesis.

Protein family review   

(26 August 2009)

Claudins are crucial components of tight junctions and are important in regulating permeability and maintaining cell polarity in cell sheets.

Protein family review   

(15 June 2009)

A review of the cytoskeleton-organizing WASP and WAVE family proteins.

Protein family review   

(17 March 2009)

The proteins of the origin recognition complex are found throughout all eukaryotes and have roles beyond that of DNA replication.

Protein family review    

(19 November 2008)

Hedgehog proteins, which are important in developmental signaling, have been joined by other newly discovered proteins from throughout the eukaryotes in the Hint-domain-containing group of proteins.