Biology for the post-genomic era

Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.


  • Clare Garvey PhD, Genome Biology


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  • Gene body methylation

    Gene body methylation is as important as promoter methylation in identifying silenced genes, with histone modifications also contributing to regulation

    Genome Biology 2014, 15:408
  • ChIP-seq zinger motifs

    An analysis of the novel common TF binding site motif – zinger motif – reveals the need for careful analysis of ChIP-seq data

    Genome Biology 2014, 15:412
  • Circular RNAs

    An analysis of ENCODE data reveals circular mRNAs and casts doubt on the theory that they might act as miRNA sponges

    Genome Biology 2014, 15:409
  • Corset

    Corset is a method that hierarchically clusters contigs and summarizes read counts for analyzing differential expression in de novo assembled transcriptomes

    Genome Biology 2014, 15:410
  • One year’s microbiome

    Changes in the saliva and gut microbiome of two individuals over the course of a year

    Genome Biology 2014, 15:R89
  • R2TP chaperone acitivty

    This study in yeast explores the molecular basis of how the R2TP complex is required for box C/D snoRNP assembly

    Genome Biology 2014, 15:404
  • Human positive selection

    An analysis of 1000 Genomes data identifies regions in the human genome with unusually high differentiation between populations

    Genome Biology 2014, 15:R88
  • Plant immune responses

    Transcriptomic responses to flg22 in wild type, mpk3, mpk4 and mpk6 plants determines how SA signaling and callose deposition are regulated

    Genome Biology 2014, 15:R87
  • Bias in RNA-seq

    A new approach, in vitro transcription sequencing, reveals RNA-seq coverage biases introduced by library preparation protocols

    Genome Biology 2014, 15:R86
  • Topological domain borders

    Architectural protein binding sites at topologically associated domain borders help define insulator strength

    Genome Biology 2014, 15:R82
  • Bimodal PolII peaks

    Analysis of PolII ChIP-seq datasets reveals a characteristic profile of two peaks at transcription start sites in mouse and human

    Genome Biology 2014, 15:R85

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Genome Biology Volume 15 Issue 6

The complete issue of Genome Biology Volume 15 Issue 6 is now available.

Free webinar on plant genomics:

Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.

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ISSN: 1465-6906