Biology for the post-genomic era

Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.


  • Clare Garvey PhD, Genome Biology


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  • Cell-free DNA

    Bardelli and Siravegna on the liquid biopsies: how DNA circulating in the blood is used as a diagnostic tool in cancer

    Genome Biology 2014, 15:449
  • Single cell genomics

    Nick Navin reviews new techniques and strategies to study cancer at the single cell level

    Genome Biology 2014, 15:452
  • X chromosome sequencing

    A new approach using deep sequencing of X chromosome allows the study of cancer progression in colorectal cancer

    Genome Biology 2014, 15:437
  • AML-related methylation regulation

    An analysis of DNA methylation changes during AML's treatment with DNMT inhibitors identifies genes specifically targeted by the drugs

    Genome Biology 2014, 15:406
  • Circulating tumor cells

    Johann de Bono and colleagues on the frontiers of cancer monitoring with ciculating tumor cells

    Genome Biology 2014, 15:448
  • Colorectal cancer mutations

    An analysis of the deep targeted sequencing and WGS of matched primary and metastatic colorectal cancer shows high mutations concordance

    Genome Biology 2014, 15:454
  • OrthoClust

    Mark Gerstein and colleagues describe a new orthology-based framework for cross-species clustering

    Genome Biology 2014, 15:R100
  • Copy number evolution

    An analysis of the evolution of DNA copy numbers in the fruit fly

    Genome Biology 2014, 15:R70
  • Breast cancer classification

    IntClust is a genome-driven breast cancer classifier which subtypes these cancers based on gene expression alone

    Genome Biology 2014, 15:431
  • Tumor heterogeneity

    Charles Swanton and colleagues review the ins and outs of intratumor heterogeneity and how does it affect personalized medicine

    Genome Biology 2014, 15:453
  • Gastric cancer N-of-1

    David Adams and colleagues discuss the elegant approach for the cancer evolution studies, combining sequencing with the clever choice of cancer models

    Genome Biology 2014, 15:444

Featured free review

The indoor microbiomeThe indoor microbiome

Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.



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Latest issue

Genome Biology Volume 15 Issue 8

The complete issue of Genome Biology Volume 15 Issue 8 is now available.

Free webinar on plant genomics:

Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.

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ISSN: 1465-6906