Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
- Louisa Flintoft PhD, Genome Biology
John Novembre and colleagues reflect on the recent ASHG 2014 meeting in San Diego.
The kPAL package assesses the quality of sequencing datasets, detects technical artifacts and differences in library preparation protocols
Analysis of a mouse cross reveals host genes that alter the gut microbiome in addition to dietary factors that do
A combined analysis of immunohistochemical and genomic data for ovarian cancer reveals that PTEN loss is a common and prognostic driver event
Comparisons of the genomes of the endangered crested ibis and the little egret reveals the effects near-extinction has on genomes
Evidence from 48 avian genomes suggests that GC-biased gene conversion is more effective in large populations with shorter generation time
Kr/Kc correlates with body mass, whereas dN/dS is negatively correlated, suggesting that dN/dS is a poor measure for estimating selection
A survey of 48 sequenced bird genomes reveals a relatively small number of endogenous viral elements
A new method for the identification of essential genes from
CRISPR/Cas9 knockout screens
The exon junction complex is shown to have a role in regulating alternative splicing and this is linked to Pol II
DESeq2 is the follow-up to the popular DESeq package for RNA-seq analysis, with new features for better results
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.
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Free webinar on plant genomics:
Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.
From the blog
Avian genomes collection
Published: 11 December 2014
Last updated: 13 December 2014
Genomics of infectious diseases special issue
Published: 3 November 2014
Last updated: 29 November 2014
The genomics of cancer progression and heterogeneity
Published: 7 August 2014
Last updated: 3 December 2014