Biology for the post-genomic era

Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.


  • Louisa Flintoft PhD, Genome Biology


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  • Surfing data waves

    John Novembre and colleagues reflect on the recent ASHG 2014 meeting in San Diego.

    Genome Biology 2014, 15:562
  • kPAL: quality assessment

    The kPAL package assesses the quality of sequencing datasets, detects technical artifacts and differences in library preparation protocols

    Genome Biology 2014, 15:555
  • Gut microbiome genetics

    Analysis of a mouse cross reveals host genes that alter the gut microbiome in addition to dietary factors that do

    Genome Biology 2014, 15:552
  • Ovarian cancer driver

    A combined analysis of immunohistochemical and genomic data for ovarian cancer reveals that PTEN loss is a common and prognostic driver event

    Genome Biology 2014, 15:526
  • Crested ibis genome

    Comparisons of the genomes of the endangered crested ibis and the little egret reveals the effects near-extinction has on genomes

    Genome Biology 2014, 15:557
  • Biased gene conversion

    Evidence from 48 avian genomes suggests that GC-biased gene conversion is more effective in large populations with shorter generation time

    Genome Biology 2014, 15:549
  • Population size proxies

    Kr/Kc correlates with body mass, whereas dN/dS is negatively correlated, suggesting that dN/dS is a poor measure for estimating selection

    Genome Biology 2014, 15:542
  • Avian endogenous viruses

    A survey of 48 sequenced bird genomes reveals a relatively small number of endogenous viral elements

    Genome Biology 2014, 15:539
  • MaGeCK

    A new method for the identification of essential genes from CRISPR/Cas9 knockout screens

    Genome Biology 2014, 15:554
  • Exon junction complex

    The exon junction complex is shown to have a role in regulating alternative splicing and this is linked to Pol II

    Genome Biology 2014, 15:551
  • DESeq2

    DESeq2 is the follow-up to the popular DESeq package for RNA-seq analysis, with new features for better results

    Genome Biology 2014, 15:550

Featured review

The indoor microbiomeThe indoor microbiome

Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.



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ISSN: 1465-6906