Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
- Clare Garvey PhD, Genome Biology
Changes in the saliva and gut microbiome of two individuals over the course of a year
This study in yeast explores the molecular basis of how the R2TP complex is required for box C/D snoRNP assembly
An analysis of 1000 Genomes data identifies regions in the human genome with unusually high differentiation between populations
Transcriptomic responses to flg22 in wild type, mpk3, mpk4 and mpk6 plants determines how SA signaling and callose deposition are regulated
A new approach, in vitro transcription sequencing, reveals RNA-seq coverage biases introduced by library preparation protocols
Architectural protein binding sites at topologically associated domain borders help define insulator strength
Sequencing of fecal microbiota in children under the age of five sheds new light on pathogens associated with diarrheal disease
Analysis of PolII ChIP-seq datasets reveals a characteristic profile of two peaks at transcription start sites in mouse and human
A new method for the sensitive discovery of structural variants from low coverage data
An analysis of specific miRNA editing events uncovers several that have been conserved between mammals and bony fish
Depletion of the three human TET proteins individually reveals overlapping roles for them in the conversion of 5mC to 5hmC
Featured free review
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.
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Free webinar on plant genomics:
Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.