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1: Science. 1999 Apr 2;284(5411):151-3.
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ROUGH SHEATH2: a Myb protein that represses knox homeobox genes in maize lateral organ primordia.

Timmermans MC, Hudson A, Becraft PW, Nelson T.

Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.

The regulation of members of the knotted1-like homeobox (knox) gene family is required for the normal initiation and development of lateral organs. The maize rough sheath2 (rs2) gene, which encodes a Myb-domain protein, is expressed in lateral organ primordia and their initials. Mutations in the rs2 gene permit ectopic expression of knox genes in leaf and floral primordia, causing a variety of developmental defects. Ectopic KNOX protein accumulation in rs2 mutants occurs in a subset of the normal rs2-expressing cells. This variegated accumulation of KNOX proteins in rs2 mutants suggests that rs2 represses knox expression through epigenetic means.

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PMID: 10102816 [PubMed - indexed for MEDLINE]