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1: Genome Biol. 2003;5(1):201. Epub 2003 Dec 23.
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Computational prediction of transcription-factor binding site locations.

Bulyk ML.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, New Research Building, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. mlbulyk@rascal.med.harvard.edu

Identifying genomic locations of transcription-factor binding sites, particularly in higher eukaryotic genomes, has been an enormous challenge. Various experimental and computational approaches have been used to detect these sites; methods involving computational comparisons of related genomes have been particularly successful.

Publication Types:
PMID: 14709165 [PubMed - indexed for MEDLINE]

PMCID: PMC395725