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1: J Am Chem Soc. 2004 Dec 1;126(47):15340-1.
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High-resolution NMR spectroscopy of membrane proteins in aligned bicelles.

De Angelis AA, Nevzorov AA, Park SH, Howell SC, Mrse AA, Opella SJ.

Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0307, USA.

High-resolution solid-state NMR spectra can be obtained from uniformly (15)N-labeled membrane proteins in magnetically aligned bicelles. Fast uniaxial diffusion about the axis of the bilayer normal results in single-line spectra that contain the orientational information necessary for protein structure determination.

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PMID: 15563135 [PubMed - indexed for MEDLINE]