Your browser version may not work well with NCBI's Web applications. More information here...
1: Science. 2004 Dec 24;306(5705):2255-7.
Related Articles, Links
Click here to read Click here to read
Mouse brain organization revealed through direct genome-scale TF expression analysis.

Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q.

Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.

In the developing brain, transcription factors (TFs) direct the formation of a diverse array of neurons and glia. We identifed 1445 putative TFs in the mouse genome. We used in situ hybridization to map the expression of over 1000 of these TFs and TF-coregulator genes in the brains of developing mice. We found that 349 of these genes showed restricted expression patterns that were adequate to describe the anatomical organization of the brain. We provide a comprehensive inventory of murine TFs and their expression patterns in a searchable brain atlas database.

Publication Types:
PMID: 15618518 [PubMed - indexed for MEDLINE]