PhyloFacts: an online structural phylogenomic encyclopedia for protein functional and structural classification.
Krishnamurthy N, Brown DP, Kirshner D, Sjölander K.
Department of Bioengineering, 473 Evans Hall #1762, University of California, Berkeley, CA 94720, USA.
The Berkeley Phylogenomics Group presents PhyloFacts, a structural phylogenomic encyclopedia containing almost 10,000 'books' for protein families and domains, with pre-calculated structural, functional and evolutionary analyses. PhyloFacts enables biologists to avoid the systematic errors associated with function prediction by homology through the integration of a variety of experimental data and bioinformatics methods in an evolutionary framework. Users can submit sequences for classification to families and functional subfamilies. PhyloFacts is available as a worldwide web resource from http://phylogenomics.berkeley.edu/phylofacts.
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PMID: 16973001 [PubMed - indexed for MEDLINE]PMCID: PMC1794543