Physicochemical modelling of cell signalling pathways.
Aldridge BB, Burke JM, Lauffenburger DA, Sorger PK.
Center for Cell Decision Processes, Department Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Physicochemical modelling of signal transduction links fundamental chemical and physical principles, prior knowledge about regulatory pathways, and experimental data of various types to create powerful tools for formalizing and extending traditional molecular and cellular biology.
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PMID: 17060902 [PubMed - indexed for MEDLINE]