Tilescope: online analysis pipeline for high-density tiling microarray data.
Zhang ZD, Rozowsky J, Lam HY, Du J, Snyder M, Gerstein M.
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. zhengdong.zhang@yale.edu
We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data http://tilescope.gersteinlab.org. In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.
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PMID: 17501994 [PubMed - indexed for MEDLINE]PMCID: PMC1929149