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1: Genome Biol. 2008 Apr 25;9(4):217. [Epub ahead of print]
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New tricks for old NODs.

Pietras EM, Cheng G.

Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA 90095, USA. gcheng@mednet.ucla.edu.

ABSTRACT: Recent work has identified the human NOD-like receptor NLRX1 as a negative regulator of intracellular signaling leading to type I interferon production. Here we discuss these findings and the questions and implications they raise regarding the function of NOD-like receptors in the antiviral response.

PMID: 18466630 [PubMed - as supplied by publisher]