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Molecular genetics of plant disease resistance.

Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD.

Department of Plant Biology, University of California, Berkeley 94720, USA.

Plant breeders have used disease resistance genes (R genes) to control plant disease since the turn of the century. Molecular cloning of R genes that enable plants to resist a diverse range of pathogens has revealed that the proteins encoded by these genes have several features in common. These findings suggest that plants may have evolved common signal transduction mechanisms for the expression of resistance to a wide range of unrelated pathogens. Characterization of the molecular signals involved in pathogen recognition and of the molecular events that specify the expression of resistance may lead to novel strategies for plant disease control.

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PMID: 7732374 [PubMed - indexed for MEDLINE]