Organization of DNA sequences near the centromere of the Drosophila melanogaster Y chromosome.
Losada A, Abad JP, Villasante A.
Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), E-28049 Madrid, Spain.
The structural analysis of a yeast artificial chromosome clone from Drosophila melanogaster enriched in dodecasatellite sequences has led us to find a new retrotransposon that we have called Circe. Moreover, this retrotransposon has allowed the isolation of a contig encompassing approximately 200 kb near the centromere of the Y chromosome, providing an entry point into a region from which very little sequence information has been obtained to date. The molecular characterization of the contig has shown the presence of HeT-A telomeric retrotransposons close to the centromere of the Y chromosome, suggesting a telocentric origin for this submetacentric chromosome.
PMID: 9426282 [PubMed - indexed for MEDLINE]