Biology for the post-genomic era

Fully Open Access. Genome Biology covers all areas of biology and biomedicine studied from a genomic and post-genomic perspective. Content includes research, new methods and software tools, and reviews, opinions and commentaries. Areas covered include, but are not limited to: sequence analysis; bioinformatics; insights into molecular, cellular and organismal biology; functional genomics; epigenomics; population genomics; proteomics; comparative biology and evolution; systems and network biology; genomics of disease; and clinical genomics. All content is open access immediately on publication.

Editor

  • Louisa Flintoft PhD, Genome Biology

Articles

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  • Skin hypomethylation blocks

    Large blocks of DNA hypomethylation found to be associated with age and sun exposure in skin

    Genome Biology 2015, 16:80
  • Cell-free DNA methylation

    Bisulfite sequencing of cell-free circulating DNA from pregnant women is able to identify placental hypomethylated domains

    Genome Biology 2015, 16:78
  • Sperm chromosome organization

    Comparing chromosome organization in mouse sperm and fibroblasts suggests that packaging chromosomes in sperm does not result in large changes

    Genome Biology 2015, 16:77
  • NAHR identification

    New method for the identification of non-allelic homologous recombination from the low coverage sequencing data

    Genome Biology 2015, 16:72
  • Host-microbiome interaction analysis

    Microbiome and host transcriptome analysis of ulcerative colitis patients following IPAA surgery

    Genome Biology 2015, 16:67
  • Cancer therapy response

    An analysis of lung cancer cell lines gene expression in response to drug treatment reveals differential response on the single-cell level

    Genome Biology 2015, 16:66
  • Fasciola hepatica genome

    The genome of the liver fluke Fasciola hepatica is among the largest known for any pathogen, with a size of 1.3Gb

    Genome Biology 2015, 16:71
  • Prognostic perturbation signature

    Denoising perturbation signatures reveals an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine treated ER+ breast cancer

    Genome Biology 2015, 16:61
  • Colon cancer 5hmC

    Promoters 5-hydroxymethylated during normal colon differentiation are resistant to neoplastic hypermethylation

    Genome Biology 2015, 16:69
  • Network hierarchy

    A metric is devised for determining and measuring network hierarchy and then applied to the phosphorylome and regulome networks

    Genome Biology 2015, 16:63
  • Colorectal cancer immunophenotypes

    Analysis of colorectal cancer immunophenotypes reveals a tumor escape mechanism and identifies novel cancer immunotherapy candidates

    Genome Biology 2015, 16:64
3D Organisation of the nucleus
Genome Editing
Genome Biology Single Cell
Genomics of infectious diseases: special issue
Avian Genomes collection

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ISSN: 1465-6906