Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
- Clare Garvey PhD, Genome Biology
It is possible to reconstruct proportions of cell subtypes in whole blood samples by using DNA methylation data
Fuchou Tang and colleagues map 5-methylcytosine and, for the first time ever at single-base resolution, 5-hydroxymethylcytosine in the human brain
Analysis of oncogenesis-related non-coding RNAs identifies a new class of cryptic macroRNAs, which seem to regulate aggressive tumors
Drug sensitivity can be predicted in a patient using only before-treatment gene expression data from primary tumor biopsies
Steven Salzberg's new method for providing taxonomic assignments to metagenomic reads is considerably faster than existing approaches
Increasing ambient temperature raises transcript abundance by promoting faster transcription relative to decay and not vice versa in Arabidopsis
In bacteria, genes in different functional classes display unique codon usage signatures, such that gene function can be predicted
The genome and developmental transcriptome of Globodera pallida, a cyst nematode pathogen of potato, provide insights into nematode biology
An extensive comparison of genome scaffolding tools finds that the overall best perfomers are SGA, SOPRA and SSPACE
Dynamic changes in the DNA binding activity of APETALA1 and SEPELATA3 regulate chromatin accessibility and gene expression changes
A comprehensive analysis of RNA-seq, ESTs and genome sequence annotations identifies more than 19,000 lncRNAs in maize
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New methods for mapping histones at higher resolution open many new doors in epigenomics research.
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Free webinar on plant genomics:
Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.
From the blog
- 28 February 2014
- Methylating much?