Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
- Clare Garvey PhD, Genome Biology
An analysis of a breast cancer cohort reveals large methylation changes and demonstrates a prognostic value of a DNA methylation signature
Methylome analysis of Wilms tumor identifies differentially methylated biomarker regions that can be detected in cell-free circulating DNA
This study in yeast explores the molecular basis of how the R2TP complex is required for box C/D snoRNP assembly
Sequencing of VDJ rearrangements and analysis of somatic hypermutations reveals two distinct clonal evolution modes in diffuse large B-cell lymphoma
Many lung cancer-associated lncRNAs and their role in tumorigenesis are revealed in a transcriptional analysis
Bartha Knoppers and colleagues discuss the data-sharing models that can inform genomic data-sharing strategies
Michael Berger and Anna Varghese describe the difficulties we face when translating genomic cancer research into the clinical setting
A new single molecule tagging method helps identify PCR duplicates and simplifies analyses of clonal evolution and heterogeneity in cancer
A new method for tumor purity analysis and differential methylation detection in a single tumor sample
A new method for effective allele-specific expression detection when no genotype is available
Stefan Müller and Arnab Nayak review the versatile protein family of SUMO-specific proteases / isopeptidases
Featured free review
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.
Latest articles from Genome Medicine
Genome Medicine 2014, 6:59
Genome Medicine 2014, 6:60
Genome Medicine 2014, 6:58
Genome Medicine 2014, 6:56
Free webinar on plant genomics:
Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.