The sequence of human chromosome 21 and implications for research into Down syndrome.

Gardiner K, Davisson M.

Genome Biol. 2000;1(2):REVIEWS0002. Epub 2000 Aug 4. Review.

PMID: 11178230 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions.

Gardiner K, Fortna A, Bechtel L, Davisson MT.

Gene. 2003 Oct 30;318:137-47.

PMID: 14585506 [PubMed - indexed for MEDLINE]

Related Articles

Chromosome 21 and down syndrome: from genomics to pathophysiology.

Antonarakis SE, Lyle R, Dermitzakis ET, Reymond A, Deutsch S.

Nat Rev Genet. 2004 Oct;5(10):725-38. Review.

PMID: 15510164 [PubMed - indexed for MEDLINE]

Related Articles

Differential gene expression studies to explore the molecular pathophysiology of Down syndrome.

Antonarakis SE, Lyle R, Chrast R, Scott HS.

Brain Res Brain Res Rev. 2001 Oct;36(2-3):265-74. Review.

PMID: 11690624 [PubMed - indexed for MEDLINE]

Related Articles

The proteins of human chromosome 21.

Gardiner K, Costa AC.

Am J Med Genet C Semin Med Genet. 2006 Aug 15;142C(3):196-205.

PMID: 17048356 [PubMed - indexed for MEDLINE]

Related Articles

Trisomy 21 and Down syndrome: a short review.

Sommer CA, Henrique-Silva F.

Braz J Biol. 2008 May;68(2):447-52. Review.

PMID: 18660978 [PubMed - indexed for MEDLINE]

Related Articles

Comparative genomic sequence analysis of the human chromosome 21 Down syndrome critical region.

Toyoda A, Noguchi H, Taylor TD, Ito T, Pletcher MT, Sakaki Y, Reeves RH, Hattori M.

Genome Res. 2002 Sep;12(9):1323-32.

PMID: 12213769 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K.

Hum Mol Genet. 2004 Jul 1;13(13):1333-40. Epub 2004 May 11.

PMID: 15138197 [PubMed - indexed for MEDLINE]

Related Articles

Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome.

Lyle R, Gehrig C, Neergaard-Henrichsen C, Deutsch S, Antonarakis SE.

Genome Res. 2004 Jul;14(7):1268-74.

PMID: 15231743 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

A gene expression map of human chromosome 21 orthologues in the mouse.

Gitton Y, Dahmane N, Baik S, Ruiz i Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML; HSA21 expression map initiative.

Nature. 2002 Dec 5;420(6915):586-90.

PMID: 12466855 [PubMed - indexed for MEDLINE]

Related Articles

Human chromosome 21 gene expression atlas in the mouse.

Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A.

Nature. 2002 Dec 5;420(6915):582-6.

PMID: 12466854 [PubMed - indexed for MEDLINE]

Related Articles

Down syndrome mouse models are looking up.

Reeves RH.

Trends Mol Med. 2006 Jun;12(6):237-40. Epub 2006 May 4.

PMID: 16677859 [PubMed - indexed for MEDLINE]

Related Articles

Genetic basis for a mouse model of Down syndrome.

Reeves RH, Gearhart JD, Littlefield JW.

Brain Res Bull. 1986 Jun;16(6):803-14. Review.

PMID: 2944567 [PubMed - indexed for MEDLINE]

Related Articles

Gene-dosage effects in Down syndrome and trisomic mouse models.

Gardiner K.

Genome Biol. 2004;5(10):244. Epub 2004 Sep 30. Review.

PMID: 15461808 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis.

Gardiner K, Slavov D, Bechtel L, Davisson M.

Genomics. 2002 Jun;79(6):833-43.

PMID: 12036298 [PubMed - indexed for MEDLINE]

Related Articles

Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome.

Akeson EC, Lambert JP, Narayanswami S, Gardiner K, Bechtel LJ, Davisson MT.

Cytogenet Cell Genet. 2001;93(3-4):270-6.

PMID: 11528125 [PubMed - indexed for MEDLINE]

Related Articles

Down syndrome and mouse models.

Kola I, Hertzog PJ.

Curr Opin Genet Dev. 1998 Jun;8(3):316-21. Review.

PMID: 9690992 [PubMed - indexed for MEDLINE]

Related Articles

Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes.

Aït Yahya-Graison E, Aubert J, Dauphinot L, Rivals I, Prieur M, Golfier G, Rossier J, Personnaz L, Creau N, Bléhaut H, Robin S, Delabar JM, Potier MC.

Am J Hum Genet. 2007 Sep;81(3):475-91. Epub 2007 Jul 19.

PMID: 17701894 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Physical and comparative mapping of distal mouse chromosome 16. 5 p5.

Cabin DE, McKee-Johnson JW, Matesic LE, Wiltshire T, Rue EE, Mjaatvedt AE, Huo YK, Korenberg JR, Reeves RH.

Genome Res. 1998 Sep;8(9):940-50.

PMID: 9750193 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Functional genomics: a time and place for every gene.

Reeves RH.

Nature. 2002 Dec 5;420(6915):518-9. No abstract available.

PMID: 12466849 [PubMed - indexed for MEDLINE]

Related Articles