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Items 1 - 20 of 108
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1:

Chemical genomics: what will it take and who gets to play?

MacBeath G.

Genome Biol. 2001;2(6):COMMENT2005. Epub 2001 Jun 6.

PMID: 11423004 [PubMed - indexed for MEDLINE]

2:

Target validation and drug discovery using genomic and protein-protein interaction technologies.

Pillutla RC, Fisher PB, Blume AJ, Goldstein NI.

Expert Opin Ther Targets. 2002 Aug;6(4):517-31. Review.

PMID: 12223066 [PubMed - indexed for MEDLINE]

3:

Forward & reverse chemical genetics using SPOS-based combinatorial chemistry.

Thorpe DS.

Comb Chem High Throughput Screen. 2003 Nov;6(7):623-47. Review.

PMID: 14683491 [PubMed - indexed for MEDLINE]

4:

Forecasting roles of combinatorial chemistry in the age of genomically derived drug discovery targets.

Thorpe DS.

Comb Chem High Throughput Screen. 2000 Oct;3(5):421-36. Review.

PMID: 11032958 [PubMed - indexed for MEDLINE]

5:

Functional genomics and cardiovascular drug discovery.

Lee RT.

Circulation. 2001 Sep 18;104(12):1441-6. Review. No abstract available.

PMID: 11560863 [PubMed - indexed for MEDLINE]

6:

1536-well assay plates: when do they make sense?

Garyantes TK.

Drug Discov Today. 2002 May 1;7(9):489-90. No abstract available.

PMID: 11983557 [PubMed - indexed for MEDLINE]

7:

Chemical genomics versus orthodox drug development.

Szymkowski DE.

Drug Discov Today. 2003 Feb 15;8(4):157-9. No abstract available.

PMID: 12581708 [PubMed - indexed for MEDLINE]

8:

Chemical dimerizers and three-hybrid systems: scanning the proteome for targets of organic small molecules.

Kley N.

Chem Biol. 2004 May;11(5):599-608. Review.

PMID: 15157871 [PubMed - indexed for MEDLINE]

9:

Strategies for facilitated forward chemical genetics.

Khersonsky SM, Chang YT.

Chembiochem. 2004 Jul 5;5(7):903-8. Review. No abstract available.

PMID: 15239045 [PubMed - indexed for MEDLINE]

10:

Inkjet dispensing technology: applications in drug discovery.

Lemmo AV, Rose DJ, Tisone TC.

Curr Opin Biotechnol. 1998 Dec;9(6):615-7. Review.

PMID: 9889139 [PubMed - indexed for MEDLINE]

11:

Molecular recognition: identifying compounds and their targets.

Fernandes PB.

J Cell Biochem Suppl. 2001;Suppl 37:1-6. Review.

PMID: 11842421 [PubMed - indexed for MEDLINE]

12:

[Development of antituberculous drugs: current status and future prospects]

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID: 17240921 [PubMed - indexed for MEDLINE]

13:

Anticancer drug discovery using chemical genomics.

Sehgal A.

Curr Med Chem. 2003 May;10(9):749-55. Review.

PMID: 12678778 [PubMed - indexed for MEDLINE]

14:

Advancing drug discovery through systems biology.

Davidov E, Holland J, Marple E, Naylor S.

Drug Discov Today. 2003 Feb 15;8(4):175-83. Review.

PMID: 12581712 [PubMed - indexed for MEDLINE]

15:

Pharmaceutical proteomics.

Steiner S, Anderson NL.

Ann N Y Acad Sci. 2000;919:48-51.

PMID: 11083096 [PubMed - indexed for MEDLINE]

16:

Gene expression profiling in the discovery, optimization and development of novel drugs: one universal screening platform.

Bol D, Ebner R.

Pharmacogenomics. 2006 Mar;7(2):227-35. Review.

PMID: 16515402 [PubMed - indexed for MEDLINE]

17:

The principle of complementarity: chemical versus biological space.

Haggarty SJ.

Curr Opin Chem Biol. 2005 Jun;9(3):296-303. Review.

PMID: 15939332 [PubMed - indexed for MEDLINE]

18:

Object-oriented approach to drug design enabled by NMR SOLVE: first real-time structural tool for characterizing protein-ligand interactions.

Sem DS, Yu L, Coutts SM, Jack R.

J Cell Biochem Suppl. 2001;Suppl 37:99-105. Review.

PMID: 11842434 [PubMed - indexed for MEDLINE]

19:

Fulfilling the promise: drug discovery in the post-genomic era.

Chanda SK, Caldwell JS.

Drug Discov Today. 2003 Feb 15;8(4):168-74. Review.

PMID: 12581711 [PubMed - indexed for MEDLINE]

20:

Drug discovery and development using chemical genomics.

Sehgal A.

Curr Opin Drug Discov Devel. 2002 Jul;5(4):526-31. Review.

PMID: 12197310 [PubMed - indexed for MEDLINE]

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