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1:

HIV: master of the host cell.

Arendt CW, Littman DR.

Genome Biol. 2001;2(11):REVIEWS1030. Epub 2001 Oct 22. Review.

PMID: 11737949 [PubMed - indexed for MEDLINE]

2:

Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction.

Fortin JF, Barat C, Beauséjour Y, Barbeau B, Tremblay MJ.

J Biol Chem. 2004 Sep 17;279(38):39520-31. Epub 2004 Jul 16. Erratum in: J Biol Chem. 2005 Mar 11;280(10):9752.

PMID: 15258149 [PubMed - indexed for MEDLINE]

3:

Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection.

Venzke S, Michel N, Allespach I, Fackler OT, Keppler OT.

J Virol. 2006 Nov;80(22):11141-52. Epub 2006 Aug 23.

PMID: 16928758 [PubMed - indexed for MEDLINE]

4:

Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases.

Acheampong EA, Parveen Z, Muthoga LW, Kalayeh M, Mukhtar M, Pomerantz RJ.

J Virol. 2005 Apr;79(7):4257-69.

PMID: 15767427 [PubMed - indexed for MEDLINE]

5:

The multifaceted role of HIV Nef.

Mangasarian A, Trono D.

Res Virol. 1997 Jan-Feb;148(1):30-3. Review. No abstract available.

PMID: 9017830 [PubMed - indexed for MEDLINE]

6:

HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection.

Swingler S, Brichacek B, Jacque JM, Ulich C, Zhou J, Stevenson M.

Nature. 2003 Jul 10;424(6945):213-9.

PMID: 12853962 [PubMed - indexed for MEDLINE]

8:

Human immunodeficiency virus type 1 Nef activates p21-activated kinase via recruitment into lipid rafts.

Krautkrämer E, Giese SI, Gasteier JE, Muranyi W, Fackler OT.

J Virol. 2004 Apr;78(8):4085-97.

PMID: 15047825 [PubMed - indexed for MEDLINE]

9:

Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.

Hrecka K, Swigut T, Schindler M, Kirchhoff F, Skowronski J.

J Virol. 2005 Aug;79(16):10650-9.

PMID: 16051857 [PubMed - indexed for MEDLINE]

10:

Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.

Matarrese P, Malorni W.

Cell Death Differ. 2005 Aug;12 Suppl 1:932-41. Review. Erratum in: Cell Death Differ. 2006 May;13(5):876.

PMID: 15818415 [PubMed - indexed for MEDLINE]

11:

Elucidating effects of long-term expression of HIV-1 Nef on astrocytes by microarray, promoter, and literature analyses.

Kramer-Hämmerle S, Hahn A, Brack-Werner R, Werner T.

Gene. 2005 Sep 26;358:31-8.

PMID: 15958282 [PubMed - indexed for MEDLINE]

12:

Modulation of specific surface receptors and activation sensitization in primary resting CD4+ T lymphocytes by the Nef protein of HIV-1.

Keppler OT, Tibroni N, Venzke S, Rauch S, Fackler OT.

J Leukoc Biol. 2006 Mar;79(3):616-27. Epub 2005 Dec 19.

PMID: 16365153 [PubMed - indexed for MEDLINE]

13:

Effects of HIV-1 Nef on cellular gene expression profiles.

Shaheduzzaman S, Krishnan V, Petrovic A, Bittner M, Meltzer P, Trent J, Venkatesan S, Zeichner S.

J Biomed Sci. 2002 Jan-Feb;9(1):82-96.

PMID: 11810028 [PubMed - indexed for MEDLINE]

14:

Role of viral regulatory and accessory proteins in HIV-1 replication.

Seelamgari A, Maddukuri A, Berro R, de la Fuente C, Kehn K, Deng L, Dadgar S, Bottazzi ME, Ghedin E, Pumfery A, Kashanchi F.

Front Biosci. 2004 Sep 1;9:2388-413. Review.

PMID: 15353294 [PubMed - indexed for MEDLINE]

15:

HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-tagged HIV-1 reporter virus.

Brown A, Gartner S, Kawano T, Benoit N, Cheng-Mayer C.

J Leukoc Biol. 2005 Sep;78(3):675-85. Epub 2005 Jul 6.

PMID: 16000390 [PubMed - indexed for MEDLINE]

16:

Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.

Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F.

Cell. 2006 Jun 16;125(6):1055-67.

PMID: 16777597 [PubMed - indexed for MEDLINE]

17:

HIV pathogenesis: Nef loses control.

Foster JL, Garcia JV.

Cell. 2006 Jun 16;125(6):1034-5.

PMID: 16777594 [PubMed - indexed for MEDLINE]

18:

HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication.

Greenway AL, Holloway G, McPhee DA, Ellis P, Cornall A, Lidman M.

J Biosci. 2003 Apr;28(3):323-35. Review.

PMID: 12734410 [PubMed - indexed for MEDLINE]

19:

Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains.

Brügger B, Krautkrämer E, Tibroni N, Munte CE, Rauch S, Leibrecht I, Glass B, Breuer S, Geyer M, Kräusslich HG, Kalbitzer HR, Wieland FT, Fackler OT.

Retrovirology. 2007 Oct 1;4:70.

PMID: 17908312 [PubMed - indexed for MEDLINE]

20:

Herpesvirus saimiri terminal membrane proteins modulate HIV-1 replication by altering Nef and Tat functions.

Raymond AD, Hasham M, Tsygankov AY, Henderson EE.

Curr HIV Res. 2007 Jan;5(1):79-86.

PMID: 17266559 [PubMed - indexed for MEDLINE]

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