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1:

Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.

Miller LD, McPhie P, Suzuki H, Kato Y, Liu ET, Cheng SY.

Genome Biol. 2004;5(5):R31. Epub 2004 Apr 29.

PMID: 15128445 [PubMed - indexed for MEDLINE]

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2:

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.

Zhang XY, Kaneshige M, Kamiya Y, Kaneshige K, McPhie P, Cheng SY.

Mol Endocrinol. 2002 Sep;16(9):2077-92.

PMID: 12198244 [PubMed - indexed for MEDLINE]

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3:

Marked potentiation of the dominant negative action of a mutant thyroid hormone receptor beta in mice by the ablation of one wild-type beta allele.

Suzuki H, Zhang XY, Forrest D, Willingham MC, Cheng SY.

Mol Endocrinol. 2003 May;17(5):895-907. Epub 2003 Feb 6.

PMID: 12576488 [PubMed - indexed for MEDLINE]

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4:

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function.

Forrest D, Hanebuth E, Smeyne RJ, Everds N, Stewart CL, Wehner JM, Curran T.

EMBO J. 1996 Jun 17;15(12):3006-15.

PMID: 8670802 [PubMed - indexed for MEDLINE]

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5:

A tumor suppressor role for thyroid hormone beta receptor in a mouse model of thyroid carcinogenesis.

Kato Y, Ying H, Willingham MC, Cheng SY.

Endocrinology. 2004 Oct;145(10):4430-8. Epub 2004 Jul 1.

PMID: 15231697 [PubMed - indexed for MEDLINE]

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6:

Isoform-dependent actions of thyroid hormone nuclear receptors: lessons from knockin mutant mice.

Cheng SY.

Steroids. 2005 May-Jun;70(5-7):450-4. Epub 2005 Mar 16. Review.

PMID: 15862829 [PubMed - indexed for MEDLINE]

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7:

Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor.

Guigon CJ, Zhao L, Lu C, Willingham MC, Cheng SY.

Mol Cell Biol. 2008 Jul;28(14):4598-608. Epub 2008 May 12.

PMID: 18474620 [PubMed - indexed for MEDLINE]

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8:

An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.

Furumoto H, Ying H, Chandramouli GV, Zhao L, Walker RL, Meltzer PS, Willingham MC, Cheng SY.

Mol Cell Biol. 2005 Jan;25(1):124-35.

PMID: 15601836 [PubMed - indexed for MEDLINE]

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9:

Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.

Wong R, Zhu XG, Pineda MA, Cheng SY, Weintraub BD.

Mol Med. 1995 Mar;1(3):306-19.

PMID: 8529109 [PubMed - indexed for MEDLINE]

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10:

Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance.

Cheng SY.

Trends Endocrinol Metab. 2005 May-Jun;16(4):176-82. Review.

PMID: 15860414 [PubMed - indexed for MEDLINE]

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12:

Cardiac glucose utilization in mice with mutated alpha- and beta-thyroid hormone receptors.

Esaki T, Suzuki H, Cook M, Shimoji K, Cheng SY, Sokoloff L, Nunez J.

Am J Physiol Endocrinol Metab. 2004 Dec;287(6):E1149-53. Epub 2004 Aug 10.

PMID: 15304375 [PubMed - indexed for MEDLINE]

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13:

Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone.

Kaneshige M, Kaneshige K, Zhu X, Dace A, Garrett L, Carter TA, Kazlauskaite R, Pankratz DG, Wynshaw-Boris A, Refetoff S, Weintraub B, Willingham MC, Barlow C, Cheng S.

Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13209-14.

PMID: 11069286 [PubMed - indexed for MEDLINE]

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14:

A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone.

O'Shea PJ, Harvey CB, Suzuki H, Kaneshige M, Kaneshige K, Cheng SY, Williams GR.

Mol Endocrinol. 2003 Jul;17(7):1410-24. Epub 2003 Apr 3.

PMID: 12677005 [PubMed - indexed for MEDLINE]

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15:

Transgenic mice bearing a human mutant thyroid hormone beta 1 receptor manifest thyroid function anomalies, weight reduction, and hyperactivity.

Wong R, Vasilyev VV, Ting YT, Kutler DI, Willingham MC, Weintraub BD, Cheng S.

Mol Med. 1997 May;3(5):303-14.

PMID: 9205946 [PubMed - indexed for MEDLINE]

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16:

Patterns of liver gene expression governed by TRbeta.

Flores-Morales A, Gullberg H, Fernandez L, Ståhlberg N, Lee NH, Vennström B, Norstedt G.

Mol Endocrinol. 2002 Jun;16(6):1257-68.

PMID: 12040013 [PubMed - indexed for MEDLINE]

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17:

N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.

Ng L, Forrest D, Haugen BR, Wood WM, Curran T.

Mol Endocrinol. 1995 Sep;9(9):1202-13.

PMID: 7491112 [PubMed - indexed for MEDLINE]

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18:

Novel functions of thyroid hormone receptor mutants: beyond nucleus-initiated transcription.

Furuya F, Ying H, Zhao L, Cheng SY.

Steroids. 2007 Feb;72(2):171-9. Epub 2006 Dec 13. Review.

PMID: 17169389 [PubMed - indexed for MEDLINE]

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19:

Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene.

Pohlenz J, Weiss RE, Macchia PE, Pannain S, Lau IT, Ho H, Refetoff S.

J Clin Endocrinol Metab. 1999 Nov;84(11):3919-28.

PMID: 10566629 [PubMed - indexed for MEDLINE]

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20:

A novel mutation (E333D) in the thyroid hormone beta receptor causing resistance to thyroid hormone syndrome.

Maraninchi M, Bourcigaux N, Dace A, El-Yazidi C, Malezet-Desmoulins C, Krempf M, Torresani J, Margotat A.

Exp Clin Endocrinol Diabetes. 2006 Nov;114(10):569-76.

PMID: 17177139 [PubMed - indexed for MEDLINE]

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