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Items 1 - 20 of 101
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1:

The cyclooxygenases.

Chandrasekharan NV, Simmons DL.

Genome Biol. 2004;5(9):241. Epub 2004 Aug 27. Review.

PMID: 15345041 [PubMed - indexed for MEDLINE]

2:

On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages.

Järving R, Järving I, Kurg R, Brash AR, Samel N.

J Biol Chem. 2004 Apr 2;279(14):13624-33. Epub 2004 Jan 19.

PMID: 14732711 [PubMed - indexed for MEDLINE]

3:

COX-3 the enzyme and the concept: steps towards highly specialized pathways and precision therapeutics?

Schwab JM, Schluesener HJ, Meyermann R, Serhan CN.

Prostaglandins Leukot Essent Fatty Acids. 2003 Nov;69(5):339-43. Review.

PMID: 14580368 [PubMed - indexed for MEDLINE]

4:

Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein.

Ballif BA, Mincek NV, Barratt JT, Wilson ML, Simmons DL.

Proc Natl Acad Sci U S A. 1996 May 28;93(11):5544-9.

PMID: 8643612 [PubMed - indexed for MEDLINE]

5:

Cyclooxygenase variants: the role of alternative splicing.

Roos KL, Simmons DL.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):62-9. Epub 2005 Aug 15. Review.

PMID: 16125668 [PubMed - indexed for MEDLINE]

6:

The zebrafish genome contains two inducible, functional cyclooxygenase-2 genes.

Ishikawa TO, Griffin KJ, Banerjee U, Herschman HR.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):181-7. Epub 2006 Nov 9.

PMID: 17112475 [PubMed - indexed for MEDLINE]

7:

A lipid peroxidation-derived inflammatory mediator: identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages.

Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M, Uchida K.

J Biol Chem. 2004 Nov 12;279(46):48389-96. Epub 2004 Sep 8.

PMID: 15355999 [PubMed - indexed for MEDLINE]

8:

Coupling between cyclooxygenases and terminal prostanoid synthases.

Ueno N, Takegoshi Y, Kamei D, Kudo I, Murakami M.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):70-6. Epub 2005 Aug 29. Review.

PMID: 16140261 [PubMed - indexed for MEDLINE]

9:

Nutritionally essential fatty acids and biologically indispensable cyclooxygenases.

Smith WL.

Trends Biochem Sci. 2008 Jan;33(1):27-37. Epub 2007 Dec 26. Review.

PMID: 18155912 [PubMed - indexed for MEDLINE]

10:

Anti-inflammatory drugs in the 21st century.

Rainsford KD.

Subcell Biochem. 2007;42:3-27. Review.

PMID: 17612044 [PubMed - indexed for MEDLINE]

11:

Prostaglandin E synthase: a novel drug target for inflammation and cancer.

Murakami M, Kudo I.

Curr Pharm Des. 2006;12(8):943-54. Review.

PMID: 16533161 [PubMed - indexed for MEDLINE]

12:

A critical role of non-active site residues on cyclooxygenase helices 5 and 6 in the control of prostaglandin stereochemistry at carbon 15.

Valmsen K, Boeglin WE, Järving R, Järving I, Varvas K, Brash AR, Samel N.

J Biol Chem. 2007 Sep 21;282(38):28157-63. Epub 2007 Jul 25.

PMID: 17652088 [PubMed - indexed for MEDLINE]

13:

Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo.

Johnsen JI, Lindskog M, Ponthan F, Pettersen I, Elfman L, Orrego A, Sveinbjörnsson B, Kogner P.

Cancer Res. 2004 Oct 15;64(20):7210-5.

PMID: 15492235 [PubMed - indexed for MEDLINE]

14:

Contribution of interaction between nitric oxide and cyclooxygenases to the production of prostaglandins in carrageenan-induced inflammation.

Toriyabe M, Omote K, Kawamata T, Namiki A.

Anesthesiology. 2004 Oct;101(4):983-90.

PMID: 15448533 [PubMed - indexed for MEDLINE]

15:

The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring.

Massoulié J, Bon S, Perrier N, Falasca C.

Chem Biol Interact. 2005 Dec 15;157-158:3-14. Epub 2005 Oct 28.

PMID: 16257397 [PubMed - indexed for MEDLINE]

16:

Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection.

Raaben M, Einerhand AW, Taminiau LJ, van Houdt M, Bouma J, Raatgeep RH, Büller HA, de Haan CA, Rossen JW.

Virol J. 2007 Jun 7;4:55.

PMID: 17555580 [PubMed - indexed for MEDLINE]

17:

Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms.

Chen B, Zhong D, Monteiro A.

BMC Genomics. 2006 Jun 17;7:156.

PMID: 16780600 [PubMed - indexed for MEDLINE]

18:

NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms.

Zhong H, Willard M, Simons J.

Int J Cancer. 2004 Nov 20;112(4):585-95.

PMID: 15382039 [PubMed - indexed for MEDLINE]

19:

Elucidation of the mechanism of inhibition of cyclooxygenases by acyl-coenzyme A and acylglucuronic conjugates of ketoprofen.

Levoin N, Blondeau C, Guillaume C, Grandcolas L, Chretien F, Jouzeau JY, Benoit E, Chapleur Y, Netter P, Lapicque F.

Biochem Pharmacol. 2004 Nov 15;68(10):1957-69.

PMID: 15476667 [PubMed - indexed for MEDLINE]

20:

Molecular characterization of the lipopolysaccharide/platelet activating factor- and zymosan-induced pathways leading to prostaglandin production in P388D1 macrophages.

Schaloske RH, Provins JW, Kessen UA, Dennis EA.

Biochim Biophys Acta. 2005 Feb 21;1687(1-3):64-75.

PMID: 15708354 [PubMed - indexed for MEDLINE]

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