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Items 1 - 20 of 375
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1:

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases.

Friesen JA, Rodwell VW.

Genome Biol. 2004;5(11):248. Epub 2004 Nov 1. Review.

PMID: 15535874 [PubMed - indexed for MEDLINE]

2:

Sequence comparisons reveal two classes of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Bochar DA, Stauffacher CV, Rodwell VW.

Mol Genet Metab. 1999 Feb;66(2):122-7.

PMID: 10068515 [PubMed - indexed for MEDLINE]

3:

Investigation of the conserved lysines of Syrian hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Bochar DA, Stauffacher CV, Rodwell VW.

Biochemistry. 1999 Nov 30;38(48):15848-52.

PMID: 10625449 [PubMed - indexed for MEDLINE]

4:

Engineering of Sulfolobus solfataricus HMG-CoA reductase to a form whose activity is regulated by phosphorylation and dephosphorylation.

Kim DY, Stauffacher CV, Rodwell VW.

Biochemistry. 2000 Mar 7;39(9):2269-75.

PMID: 10694393 [PubMed - indexed for MEDLINE]

6:

Essentiality, expression, and characterization of the class II 3-hydroxy-3-methylglutaryl coenzyme A reductase of Staphylococcus aureus.

Wilding EI, Kim DY, Bryant AP, Gwynn MN, Lunsford RD, McDevitt D, Myers JE Jr, Rosenberg M, Sylvester D, Stauffacher CV, Rodwell VW.

J Bacteriol. 2000 Sep;182(18):5147-52.

PMID: 10960099 [PubMed - indexed for MEDLINE]

7:

Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity.

Theivagt AE, Amanti EN, Beresford NJ, Tabernero L, Friesen JA.

Biochemistry. 2006 Dec 5;45(48):14397-406.

PMID: 17128979 [PubMed - indexed for MEDLINE]

9:

The structure of the catalytic portion of human HMG-CoA reductase.

Istvan ES, Deisenhofer J.

Biochim Biophys Acta. 2000 Dec 15;1529(1-3):9-18. Review.

PMID: 11111074 [PubMed - indexed for MEDLINE]

10:

Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.

Ohashi K, Osuga J, Tozawa R, Kitamine T, Yagyu H, Sekiya M, Tomita S, Okazaki H, Tamura Y, Yahagi N, Iizuka Y, Harada K, Gotoda T, Shimano H, Yamada N, Ishibashi S.

J Biol Chem. 2003 Oct 31;278(44):42936-41. Epub 2003 Aug 14.

PMID: 12920113 [PubMed - indexed for MEDLINE]

11:

Enterococcus faecalis acetoacetyl-coenzyme A thiolase/3-hydroxy-3-methylglutaryl-coenzyme A reductase, a dual-function protein of isopentenyl diphosphate biosynthesis.

Hedl M, Sutherlin A, Wilding EI, Mazzulla M, McDevitt D, Lane P, Burgner JW 2nd, Lehnbeuter KR, Stauffacher CV, Gwynn MN, Rodwell VW.

J Bacteriol. 2002 Apr;184(8):2116-22.

PMID: 11914342 [PubMed - indexed for MEDLINE]

12:

Inhibition of the class II HMG-CoA reductase of Pseudomonas mevalonii.

Hedl M, Rodwell VW.

Protein Sci. 2004 Jun;13(6):1693-7.

PMID: 15152097 [PubMed - indexed for MEDLINE]

13:

Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.

Tabernero L, Bochar DA, Rodwell VW, Stauffacher CV.

Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7167-71.

PMID: 10377386 [PubMed - indexed for MEDLINE]

14:

Identification of the catalytically important histidine of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Darnay BG, Wang Y, Rodwell VW.

J Biol Chem. 1992 Jul 25;267(21):15064-70.

PMID: 1634543 [PubMed - indexed for MEDLINE]

16:

Identification of the principal catalytically important acidic residue of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Wang Y, Darnay BG, Rodwell VW.

J Biol Chem. 1990 Dec 15;265(35):21634-41.

PMID: 2123872 [PubMed - indexed for MEDLINE]

17:

The regulated degradation of a 3-hydroxy-3-methylglutaryl-coenzyme A reductase reporter construct occurs in the endoplasmic reticulum.

Lecureux LW, Wattenberg BW.

J Cell Sci. 1994 Sep;107 ( Pt 9):2635-42.

PMID: 7844177 [PubMed - indexed for MEDLINE]

18:

Catalysis by Syrian hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proposed roles of histidine 865, glutamate 558, and aspartate 766.

Frimpong K, Rodwell VW.

J Biol Chem. 1994 Apr 15;269(15):11478-83.

PMID: 7908908 [PubMed - indexed for MEDLINE]

19:

Crystal structure of Pseudomonas mevalonii HMG-CoA reductase at 3.0 angstrom resolution.

Lawrence CM, Rodwell VW, Stauffacher CV.

Science. 1995 Jun 23;268(5218):1758-62.

PMID: 7792601 [PubMed - indexed for MEDLINE]

20:

Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.

Istvan ES, Palnitkar M, Buchanan SK, Deisenhofer J.

EMBO J. 2000 Mar 1;19(5):819-30.

PMID: 10698924 [PubMed - indexed for MEDLINE]

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