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Items 1 - 20 of 129
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1:

Cytological profiling: providing more haystacks for chemists' needles.

Lorang J, King RW.

Genome Biol. 2005;6(8):228. Epub 2005 Jul 29. Review.

PMID: 16086858 [PubMed - indexed for MEDLINE]

2:

Chemical complementation: a definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets.

Vogt A, Lazo JS.

Pharmacol Ther. 2005 Aug;107(2):212-21. Review.

PMID: 15925410 [PubMed - indexed for MEDLINE]

3:

Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats.

Seneci P, Miertus S.

Mol Divers. 2000;5(2):75-89.

PMID: 11865648 [PubMed - indexed for MEDLINE]

4:

Advances in high-throughput high-performance liquid chromatography and "purification-friendly" combinatorial library design strategies.

Schefzick S.

Adv Chromatogr. 2007;45:197-213. Review. No abstract available.

PMID: 17626560 [PubMed - indexed for MEDLINE]

5:

Fragment screening: an introduction.

Leach AR, Hann MM, Burrows JN, Griffen EJ.

Mol Biosyst. 2006 Sep;2(9):430-46.

PMID: 17153140 [PubMed - indexed for MEDLINE]

6:

An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes.

Albert JS, Blomberg N, Breeze AL, Brown AJ, Burrows JN, Edwards PD, Folmer RH, Geschwindner S, Griffen EJ, Kenny PW, Nowak T, Olsson LL, Sanganee H, Shapiro AB.

Curr Top Med Chem. 2007;7(16):1600-29. Review.

PMID: 17979771 [PubMed - indexed for MEDLINE]

7:

Recent advances in the discovery of organometallic catalysts using high-throughput screening assays.

Stambuli JP, Hartwig JF.

Curr Opin Chem Biol. 2003 Jun;7(3):420-6. Review.

PMID: 12826131 [PubMed - indexed for MEDLINE]

8:

Chemical microarray: a new tool for drug screening and discovery.

Ma H, Horiuchi KY.

Drug Discov Today. 2006 Jul;11(13-14):661-8. Review.

PMID: 16793536 [PubMed - indexed for MEDLINE]

9:

In vitro ADME medium/high-throughput screening in drug preclinical development.

Lahoz A, Gombau L, Donato MT, Castell JV, Gómez-Lechón MJ.

Mini Rev Med Chem. 2006 Sep;6(9):1053-62. Review.

PMID: 17018004 [PubMed - indexed for MEDLINE]

10:

A kinase-focused compound collection: compilation and screening strategy.

Sun D, Chuaqui C, Deng Z, Bowes S, Chin D, Singh J, Cullen P, Hankins G, Lee WC, Donnelly J, Friedman J, Josiah S.

Chem Biol Drug Des. 2006 Jun;67(6):385-94.

PMID: 16882313 [PubMed - indexed for MEDLINE]

11:

Tackling the chemogenomic space by novel screening technologies.

Mayr LM.

Ernst Schering Res Found Workshop. 2006;(58):111-73. Review.

PMID: 16709002 [PubMed - indexed for MEDLINE]

12:

Screening for ligands using a generic and high-throughput light-scattering-based assay.

Senisterra GA, Markin E, Yamazaki K, Hui R, Vedadi M, Awrey DE.

J Biomol Screen. 2006 Dec;11(8):940-8. Epub 2006 Nov 7.

PMID: 17092916 [PubMed - indexed for MEDLINE]

13:

Cell-based high-content screening of small-molecule libraries.

Korn K, Krausz E.

Curr Opin Chem Biol. 2007 Oct;11(5):503-10. Epub 2007 Oct 10. Review.

PMID: 17931958 [PubMed - indexed for MEDLINE]

14:

Complex phenotypic assays in high-throughput screening.

Clemons PA.

Curr Opin Chem Biol. 2004 Jun;8(3):334-8. Review.

PMID: 15183333 [PubMed - indexed for MEDLINE]

15:

How good is your screening library?

Irwin JJ.

Curr Opin Chem Biol. 2006 Aug;10(4):352-6. Epub 2006 Jun 21. Review.

PMID: 16797220 [PubMed - indexed for MEDLINE]

16:

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.

Holloway GA, Baell JB, Fairlamb AH, Novello PM, Parisot JP, Richardson J, Watson KG, Street IP.

Bioorg Med Chem Lett. 2007 Mar 1;17(5):1422-7. Epub 2006 Dec 3.

PMID: 17194585 [PubMed - indexed for MEDLINE]

17:

Discovery of novel targets with high throughput RNA interference screening.

Kassner PD.

Comb Chem High Throughput Screen. 2008 Mar;11(3):175-84. Review.

PMID: 18336211 [PubMed - indexed for MEDLINE]

18:

Frontal affinity chromatography for the screening of mixtures.

Chan NW, Lewis DF, Hewko S, Hindsgaul O, Schriemer DC.

Comb Chem High Throughput Screen. 2002 Aug;5(5):395-406.

PMID: 12180905 [PubMed - indexed for MEDLINE]

19:

Enhancing drug discovery through in silico screening: strategies to increase true positives retrieval rates.

Kirchmair J, Distinto S, Schuster D, Spitzer G, Langer T, Wolber G.

Curr Med Chem. 2008;15(20):2040-53. Review.

PMID: 18691055 [PubMed - indexed for MEDLINE]

20:

Combinatorial approaches to affinity chromatography.

Lowe CR.

Curr Opin Chem Biol. 2001 Jun;5(3):248-56. Review.

PMID: 11479115 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 129
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