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Items 1 - 20 of 219
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1:

Monitoring of gene knockouts: genome-wide profiling of conditionally essential genes.

Smith LK, Gomez MJ, Shatalin KY, Lee H, Neyfakh AA.

Genome Biol. 2007;8(5):R87.

PMID: 17519022 [PubMed - indexed for MEDLINE]

3:

Bacterial targets and antibiotics: genome-based drug discovery.

Gray CP, Keck W.

Cell Mol Life Sci. 1999 Nov 30;56(9-10):779-87. Review.

PMID: 11212338 [PubMed - indexed for MEDLINE]

4:

Rational identification of new antibacterial drug targets that are essential for viability using a genomics-based approach.

Chalker AF, Lunsford RD.

Pharmacol Ther. 2002 Jul;95(1):1-20. Review.

PMID: 12163125 [PubMed - indexed for MEDLINE]

5:

Functional genomics in antibacterial drug discovery.

Freiberg C, Brötz-Oesterhelt H.

Drug Discov Today. 2005 Jul 1;10(13):927-35. Review.

PMID: 15993812 [PubMed - indexed for MEDLINE]

6:

Streptococcus pneumoniae as a genomics platform for broad-spectrum antibiotic discovery.

Glass JI, Belanger AE, Robertson GT.

Curr Opin Microbiol. 2002 Jun;5(3):338-42. Review.

PMID: 12057692 [PubMed - indexed for MEDLINE]

7:

T-iDT : tool for identification of drug target in bacteria and validation by Mycobacterium tuberculosis.

Singh NK, Selvam SM, Chakravarthy P.

In Silico Biol. 2006;6(6):485-93.

PMID: 17518759 [PubMed - indexed for MEDLINE]

8:

Genome-wide screening of genes affecting glycogen metabolism in Escherichia coli K-12.

Eydallin G, Viale AM, Morán-Zorzano MT, Muñoz FJ, Montero M, Baroja-Fernández E, Pozueta-Romero J.

FEBS Lett. 2007 Jun 26;581(16):2947-53. Epub 2007 May 25.

PMID: 17543954 [PubMed - indexed for MEDLINE]

9:

How essential are nonessential genes?

Fang G, Rocha E, Danchin A.

Mol Biol Evol. 2005 Nov;22(11):2147-56. Epub 2005 Jul 13.

PMID: 16014871 [PubMed - indexed for MEDLINE]

10:

Use of genomics to select antibacterial targets.

Pucci MJ.

Biochem Pharmacol. 2006 Mar 30;71(7):1066-72. Epub 2006 Jan 18. Review.

PMID: 16412986 [PubMed - indexed for MEDLINE]

11:

The role of genomics in the discovery of novel targets for antibiotic therapy.

Ji Y.

Pharmacogenomics. 2002 May;3(3):315-23. Review.

PMID: 12052140 [PubMed - indexed for MEDLINE]

12:

Black holes, antivirulence genes, and gene inactivation in the evolution of bacterial pathogens.

Maurelli AT.

FEMS Microbiol Lett. 2007 Feb;267(1):1-8. Review.

PMID: 17233672 [PubMed - indexed for MEDLINE]

13:

Transposon-based approaches to identify essential bacterial genes.

Judson N, Mekalanos JJ.

Trends Microbiol. 2000 Nov;8(11):521-6. Review.

PMID: 11121763 [PubMed - indexed for MEDLINE]

14:

Novel targets for the future development of antibacterial agents.

McDevitt D, Payne DJ, Holmes DJ, Rosenberg M.

Symp Ser Soc Appl Microbiol. 2002;(31):28S-34S. Review.

PMID: 12481826 [PubMed - indexed for MEDLINE]

15:

Essential bacterial functions encoded by gene pairs.

Thomaides HB, Davison EJ, Burston L, Johnson H, Brown DR, Hunt AC, Errington J, Czaplewski L.

J Bacteriol. 2007 Jan;189(2):591-602. Epub 2006 Nov 17.

PMID: 17114254 [PubMed - indexed for MEDLINE]

16:

Transposon-based strategies for the identification of essential bacterial genes.

Reznikoff WS, Winterberg KM.

Methods Mol Biol. 2008;416:13-26. Review.

PMID: 18392958 [PubMed - indexed for MEDLINE]

17:

The impact of transcriptome and proteome analyses on antibiotic drug discovery.

Freiberg C, Brötz-Oesterhelt H, Labischinski H.

Curr Opin Microbiol. 2004 Oct;7(5):451-9. Review.

PMID: 15451499 [PubMed - indexed for MEDLINE]

18:

Bacterial genomics: potential for antimicrobial drug discovery.

Fritz B, Raczniak GA.

BioDrugs. 2002;16(5):331-7. Review.

PMID: 12408737 [PubMed - indexed for MEDLINE]

19:

Microbial fitness and genome dynamics.

Tønjum T, Seeberg E.

Trends Microbiol. 2001 Aug;9(8):356-8. Review. No abstract available.

PMID: 11519528 [PubMed - indexed for MEDLINE]

20:

Predicting function.

[No authors listed]

Nat Rev Microbiol. 2005 Apr;3(4):272. No abstract available.

PMID: 15818889 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 219
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