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Items 1 - 20 of 100
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1:

Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).

Wishart TM, Pemberton HN, James SR, McCabe CJ, Gillingwater TH.

Genome Biol. 2008;9(6):R101. Epub 2008 Jun 20.

PMID: 18570652 [PubMed - indexed for MEDLINE]

2:

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.

Gillingwater TH, Wishart TM, Chen PE, Haley JE, Robertson K, MacDonald SH, Middleton S, Wawrowski K, Shipston MJ, Melmed S, Wyllie DJ, Skehel PA, Coleman MP, Ribchester RR.

Hum Mol Genet. 2006 Feb 15;15(4):625-35. Epub 2006 Jan 10.

PMID: 16403805 [PubMed - indexed for MEDLINE]

3:

Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene.

Wishart TM, Paterson JM, Short DM, Meredith S, Robertson KA, Sutherland C, Cousin MA, Dutia MB, Gillingwater TH.

Mol Cell Proteomics. 2007 Aug;6(8):1318-30. Epub 2007 Apr 29.

PMID: 17470424 [PubMed - indexed for MEDLINE]

4:

The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy.

Wang MS, Fang G, Culver DG, Davis AA, Rich MM, Glass JD.

Ann Neurol. 2001 Dec;50(6):773-9.

PMID: 11761475 [PubMed - indexed for MEDLINE]

5:

The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus.

Laser H, Conforti L, Morreale G, Mack TG, Heyer M, Haley JE, Wishart TM, Beirowski B, Walker SA, Haase G, Celik A, Adalbert R, Wagner D, Grumme D, Ribchester RR, Plomann M, Coleman MP.

Mol Biol Cell. 2006 Mar;17(3):1075-84. Epub 2005 Dec 21.

PMID: 16371511 [PubMed - indexed for MEDLINE]

6:

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.

Araki T, Sasaki Y, Milbrandt J.

Science. 2004 Aug 13;305(5686):1010-3.

PMID: 15310905 [PubMed - indexed for MEDLINE]

7:

Protection of vincristine-induced neuropathy by WldS expression and the independence of the activity of Nmnat1.

Watanabe M, Tsukiyama T, Hatakeyama S.

Neurosci Lett. 2007 Jan 16;411(3):228-32. Epub 2006 Nov 17.

PMID: 17113230 [PubMed - indexed for MEDLINE]

9:

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

Mack TG, Reiner M, Beirowski B, Mi W, Emanuelli M, Wagner D, Thomson D, Gillingwater T, Court F, Conforti L, Fernando FS, Tarlton A, Andressen C, Addicks K, Magni G, Ribchester RR, Perry VH, Coleman MP.

Nat Neurosci. 2001 Dec;4(12):1199-206.

PMID: 11770485 [PubMed - indexed for MEDLINE]

10:

A local mechanism mediates NAD-dependent protection of axon degeneration.

Wang J, Zhai Q, Chen Y, Lin E, Gu W, McBurney MW, He Z.

J Cell Biol. 2005 Aug 1;170(3):349-55. Epub 2005 Jul 25.

PMID: 16043516 [PubMed - indexed for MEDLINE]

11:

Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene.

Wishart TM, Macdonald SH, Chen PE, Shipston MJ, Coleman MP, Gillingwater TH, Ribchester RR.

Mol Neurodegener. 2007 Oct 30;2:21.

PMID: 17971231 [PubMed - in process]

12:

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

Mi W, Beirowski B, Gillingwater TH, Adalbert R, Wagner D, Grumme D, Osaka H, Conforti L, Arnhold S, Addicks K, Wada K, Ribchester RR, Coleman MP.

Brain. 2005 Feb;128(Pt 2):405-16. Epub 2005 Jan 11.

PMID: 15644421 [PubMed - indexed for MEDLINE]

13:

Wlds protection distinguishes axon degeneration following injury from naturally occurring developmental pruning.

Hoopfer ED, McLaughlin T, Watts RJ, Schuldiner O, O'Leary DD, Luo L.

Neuron. 2006 Jun 15;50(6):883-95.

PMID: 16772170 [PubMed - indexed for MEDLINE]

14:

Tracking in the Wlds--the hunting of the SIRT and the luring of the Draper.

Fainzilber M, Twiss JL.

Neuron. 2006 Jun 15;50(6):819-21. Review.

PMID: 16772165 [PubMed - indexed for MEDLINE]

15:

WldS mice are resistant to paclitaxel (taxol) neuropathy.

Wang MS, Davis AA, Culver DG, Glass JD.

Ann Neurol. 2002 Oct;52(4):442-7.

PMID: 12325073 [PubMed - indexed for MEDLINE]

16:

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy.

Sasaki Y, Araki T, Milbrandt J.

J Neurosci. 2006 Aug 16;26(33):8484-91.

PMID: 16914673 [PubMed - indexed for MEDLINE]

17:

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves.

Beirowski B, Adalbert R, Wagner D, Grumme DS, Addicks K, Ribchester RR, Coleman MP.

BMC Neurosci. 2005 Feb 1;6:6.

PMID: 15686598 [PubMed - indexed for MEDLINE]

18:

Programmed axon death, synaptic dysfunction and the ubiquitin proteasome system.

Coleman MP, Ribchester RR.

Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):227-38. Review.

PMID: 15180483 [PubMed - indexed for MEDLINE]

19:

A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses.

Adalbert R, Gillingwater TH, Haley JE, Bridge K, Beirowski B, Berek L, Wagner D, Grumme D, Thomson D, Celik A, Addicks K, Ribchester RR, Coleman MP.

Eur J Neurosci. 2005 Jan;21(1):271-7.

PMID: 15654865 [PubMed - indexed for MEDLINE]

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