Genome Biology aims to provide the best possible service to authors and readers of primary research articles. The refereed research section publishes peer-reviewed research in all areas of molecular, cellular, organismal and population biology that are informed by genomics. All research articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how refereed research is published in Genome Biology and for instructions for authors, see 'about refereed research'.

Research    

(3 July 2008)

Phylogenetic mapping of metagenomics data reveals the taxonomic distribution of large DNA viruses in the sea, including giant viruses of the Mimiviridae family.

Research    

(3 July 2008)

A systematic analysis of histone modifications between human segmental duplications shows that two seemingly identical genomic copies have distinct epigenomic properties.

Research    

(22 June 2008)

A high-resolution genetic linkage map of the STIB 386 strain of Trypanosoma brucei gambiense is presented.

Research    

(20 June 2008)

Profiling of gene expression changes in mice harbouring the neurodegenerative Wlds mutation shows a strong correlation between changes in cell cycle pathways and altered vulnerability of terminally differentiated neurons.

Research    

(14 June 2008)

The nascent neo-sex chromosomes of black muntjacs show that regulatory mutations could accelerate the degeneration of the Y chromosome and contribute to the further evolution of dosage compensation.

Research    

(14 June 2008)

The expression profile of different developmental stages of the murine pancreas and predictions of transcription factor interactions, provides a framework for pancreas regulatory networks and development.

Research    

(12 June 2008)

The enrichment of specific intronic splicing enhancers upstream of weak PY tracts suggests a novel mechanism for intron recognition that compensates for a weakened canonical pre-mRNA splicing motif.

Research    

(9 June 2008)

A core of widely distributed network branches biosynthesizing at least 16 out of the 20 standard amino acids is predicted using comparative genomics.